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Cited by 16Congenital Heart Disease StudiesCardiovascular Conditions and TreatmentsCongenital heart defects research

Do the Age of Patients with Tetralogy of Fallot at the Time of Surgery and the Applied Surgical Technique Influence the Reoperation Rate?: A Single-Center Experience

Gerling, Christoph, Rukosujew, Andreas, Kehl, Hans-Gerd, Tjan, Tonny D. T., Hoffmeier, Andreas, Vogt, Johannes, Scheld, Hans-Heinrich, Krasemann, Thomas·2009·Herz Kardiovaskuläre Erkrankungen
DOI 10.1007/s00059-009-3169-x
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Abstract

Background and purpose Primary repair of tetralogy of Fallot (TOF) has been favored in many centers for years now and results and advantages of this management seem to verify this procedure. The authors wanted to know, if the age at the time of surgery and the surgical techniques had an influence on the long-term results. Patients and methods Between 1992 and 2003, 124 patients underwent complete repair of TOF at the University Hospital Münster, Germany. Patients were subdivided into two groups based on their age (< 1 year and > 1 year of age). Patients in whom a transannular patch (TAP) was used were compared with those without (NTAP), or in whom a conduit was used. Results Overall mortality was 8%, with an average age of death of 9.53 years (range 0.06-19.77 years). The patients' age at the time of surgery affected their survival as only two cases of death were reported among the group of children < 1 year of age (3.2%) whereas eight patients were older (12.9%; p = 0.0483). Six patients died within the first 30 days post surgery. Reoperation had to be performed in 21 cases, 13 (61.9%) of these patients were < 1 year of age at the time of surgery, eight were older (38.1%). A TAP, NTAP or conduit treatment did not show significant differences in long-term survival or freedom from reoperation. Conclusion Early repair of TOF within the 1st year of life can be recommended, because mortality is lower than in patients treated at a higher age. There seems no significant difference in the reintervention rate between patients treated within the 1st year of life or later.

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Authors
Gerling, C., Rukosujew, A., Kehl, H.-G., Tjan, T. D. T., Hoffmeier, A., Vogt, J., Scheld, H.-H., & Krasemann, T.
Affiliations
  • University of Münster (DE)
  • University Hospital Münster (DE)
  • Guy's Hospital (GB)
Corresponding author
Krasemann, Thomas
ORCID
Venue
Herz Kardiovaskuläre Erkrankungen
Publisher
Springer Science and Business Media LLC
Published
2009-03
Volume
34
Issue
2
Pages
155-160
ISSN
  • 0340-9937 (ISSN-L)
  • 1615-6692
DOI
10.1007/s00059-009-3169-x
OpenAlex
W1491548613
Cited by
15
References
22
Citations by year
2025: 1 · 2024: 2 · 2021: 1 · 2020: 2 · 2019: 2 · 2018: 2 · 2016: 1 · 2013: 1 · 2012: 1
FWCI
0.67
Type
journal article
Language
en
Open access
closed
Licence
www.springer.com/tdm (tdm)
Locations
  • Herz (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Epidemiology › Congenital Heart Disease Studies
  • Health Sciences › Medicine › Radiology, Nuclear Medicine and Imaging › Cardiovascular Conditions and Treatments
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Congenital heart defects research
Keywords
tetralogy of Fallot, primary repair, age at surgery, early repair, transannular patch, conduits, reoperation rate, long-term survival, postoperative mortality, pediatric cardiac surgery
MeSH terms
Adolescent, Child, Child, Preschool, Female, Germany, Humans, Infant, Infant, Newborn, Longitudinal Studies, Male, Reoperation, Risk Factors, Cardiovascular Surgical Procedures, Tetralogy of Fallot, Survival Rate, Survival Analysis, Treatment Outcome, Age Distribution, Risk Assessment, Patient Selection, Plastic Surgery Procedures, Young Adult

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