Total correction of tetralogy of Fallot in the first year of life: late results.
Open accessAbstract
Background Correction of tetralogy of Fallot in patients less than 1 year of age offers the advantage of a more normal development; but in the majority of cases exposes the patient to the possibly of a higher mortality with one-stage primary repair, and to the long-term effects of a transannular patch, which is often necessary.Methods A retrospective review of total correction of tetralogy of Fallot performed in 63 consecutive patients at less than 1 year of age was made. Risk factors for operative mortality and functional status at follow-up were analyzed. Follow-up was obtained from clinic appointments and telephone questionnaires.Results The operative mortality was 6%, with three late deaths. Aortic cross-clamp time more than 60 minutes (p = 0.023), cardiopulmonary bypass time more than 90 minutes (p = 0.016), and frequent preoperative respiratory tract infection symptoms (p = 0.008) affected operative survival; whereas age less than 3.0 months or weight less than 6.0 kg did not. Mean follow-up is 11.6 years (+/- 0.6 years, standard error). Actuarial survival is 89% (+/- 4%) and freedom from reoperation is 96% (+/- 4%) at up to 20 years after correction. Eighty-seven percent of patients have normal echocardiographic right ventricular function. Only 4 patients have greater than moderate pulmonary regurgitation by echocardiography. Three of these four patients are asymptomatic. At more than 15 years postoperatively, 88% of patients have good-to-excellent functional status.Conclusions Early correction of tetralogy of Fallot at less than 1 year of age can have a low operative mortality and provide excellent asymptomatic long-term survival.
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Atrial Flutter in a Repaired Tetralogy of Fallot Patient With Unusual Venous Anatomy
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- Authors
- Cobanoglu, A., & Schultz, J. M.
- Affiliations
- Oregon Health & Science University (US)
- Corresponding author
- Cobanoglu, Adnan
- Venue
- The Annals of Thoracic Surgery
- Publisher
- Elsevier BV
- Published
- 2002-07
- Volume
- 74
- Issue
- 1
- Pages
- 133-138
- ISSN
- 0003-4975 (ISSN-L)
- OpenAlex
- W2086950464
- Cited by
- 70
- References
- 29
- Citations by year
- 2026: 1 · 2025: 1 · 2024: 2 · 2023: 2 · 2022: 1 · 2021: 3 · 2020: 1 · 2019: 6 · 2018: 2 · 2017: 2 · 2016: 3 · 2015: 3 · 2014: 2 · 2013: 3 · 2012: 5
- FWCI
- 2.01
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- The Annals of Thoracic Surgery (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Epidemiology › Congenital Heart Disease Studies
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Congenital heart defects research
- Health Sciences › Medicine › Radiology, Nuclear Medicine and Imaging › Cardiovascular Conditions and Treatments
- Keywords
- tetralogy of Fallot, total correction, infants, postoperative mortality, transannular patch, right ventricular function, pulmonary regurgitation, long-term survival, risk factors, cardiopulmonary bypass time, aortic cross-clamp time, functional status
- MeSH terms
- Cardiopulmonary Bypass, Child, Child, Preschool, Female, Cardiac Surgical Procedures, Humans, Infant, Infant, Newborn, Male, Reoperation, Retrospective Studies, Risk Factors, Tetralogy of Fallot, Treatment Outcome, Age Distribution
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