The impact of diabetes mellitus on pelvic organ prolapse recurrence after robotic sacrocolpopexy
Abstract
Introduction and hypothesis Data examining the effect of diabetes mellitus (DM) on prolapse recurrence after sacrocolpopexy (SCP) is limited. The primary objective of this study was to determine if DM affects prolapse recurrence after robotic SCP. Methods This was a retrospective cohort study of women who underwent robotic SCP between 2012 and 2019 at Kaiser Permanente Southern California. The cohort was divided into women with and without DM at the time of SCP. The primary outcome was composite failure. Secondary outcomes included recurrent compartment-specific prolapse, reoperation rates, and surgical complications. Results Of 547 patients included, 100 had DM. Women with DM were older, had higher BMI, higher parity, and were more likely to be nonwhite. Women with DM had more advanced prolapse at baseline but were not more likely to undergo concomitant procedures at the time of SCP. Over a median follow-up of 2.1 years (IQR 1.3, 3.4), women with DM had significantly increased risk of anterior vaginal prolapse (AVP) recurrence (13% vs 3%, p<0.01), but not composite failure (21% vs 14%, p=0.14). On multivariate regression, women with DM were almost 4 times as likely to experience AVP recurrence over time (AVP hazard ratio (HR) 3.93, 95% CI 1.29-12.03, p=0.02). Conclusion In our cohort, DM was a risk factor for AVP recurrence but not composite failure after robotic SCP.
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A recent retrospective study revealed that anterior vaginal recurrence after SCP was significantly affected by diabetes, whereas CF was not significantly different between patients with and without diabetes.
“A recent retrospective study revealed that anterior vaginal recurrence after SCP was significantly affected by diabetes, whereas CF was not significantly different between patients with and without diabetes [24].”
From Composite Failure Associated With Sacrohysteropexy and Sacrocolpopexy With Supracervical Hysterectomy for Advanced Pelvic Organ Prolapse (2025) · cites this paper as [24]
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- Authors
- Eckhardt, S., Laus, K., DeAndrade, S., Lee, J., & Nguyen, J.
- Affiliations
- Kaiser Permanente (US)
- Corresponding author
- Eckhardt, Sarah
- Venue
- International Urogynecology Journal
- Published
- 2023-02-13
- Volume
- 34
- Issue
- 8
- Pages
- 1859-1866
- ISSN
- 0937-3462 (ISSN-L)
- 1433-3023
- OpenAlex
- W4320489737
- Cited by
- 12
- References
- 20
- Citations by year
- 2026: 5 · 2025: 4 · 2024: 2 · 2023: 1
- FWCI
- 2.52
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- Locations
- International Urogynecology Journal (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Rheumatology › Pelvic floor disorders treatments
- Health Sciences › Medicine › Obstetrics and Gynecology › Uterine Myomas and Treatments
- Health Sciences › Medicine › Psychiatry and Mental health › Sexual function and dysfunction studies
- Keywords
- diabetes mellitus, pelvic organ prolapse, sacrocolpopexy, robotic surgery, prolapse recurrence, cystocele, composite failure, risk factors, reoperation, surgical complications
- MeSH terms
- Diabetes Mellitus, Female, Humans, Recurrence, Retrospective Studies, Robotics, Gynecologic Surgical Procedures, Treatment Outcome, Pelvic Organ Prolapse, Robotic Surgical Procedures
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