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Antiulcerogenic activity of chlorogenic acid in different models of gastric ulcer
Shimoyama, André T., Santin, José Roberto, Machado, Isabel D., de Oliveira e Silva, Ana Mara, de Melo, Illana L. Pereira, Mancini-Filho, Jorge, Farsky, Sandra H. P.·2013·Naunyn-Schmiedeberg's Archives of Pharmacology
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Crossref · 10.1007/s00210-012-0807-2
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4 of 4 references verified0 citation errors · 0 not checkable
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“Chlorogenic acids do not modify gastric acid secretion but inhibit the migration of the neutrophils involved in the immune response and stimulate the protective action of the enzymes of the anti-oxidative cascade.”
From Effects of Coffee on the Gastro-Intestinal Tract: A Narrative Review and Literature Update (2022) · cites this paper as [81]
In the citing paper
“The authors suggest that the presence of a high level of chlorogenic acids in coffee could explain the lack of effect of coffee on stomach ulcers [81].”
From Effects of Coffee on the Gastro-Intestinal Tract: A Narrative Review and Literature Update (2022) · cites this paper as [81]
In the citing paper
“According to a study in mice, chlorogenic acids could display protective action on gastric mucosa by reducing the surface of the mucosa injured in an experimental ulcer model.”
From Effects of Coffee on the Gastro-Intestinal Tract: A Narrative Review and Literature Update (2022) · cites this paper as [81]
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Citations
Cites
Chlorogenic Acid and Caffeic Acid Are Absorbed in Humans
Olthof, M. R., Katan, M. B., & Hollman, P. C. H. (2001) · The Journal of Nutrition · doi:10.1093/jn/131.1.66 · Cited by 975
Chlorogenic Acids from Green Coffee Extract Are Highly Bioavailable in Humans
Farah, A., Monteiro, M., Donangelo, C. M., & Lafay, S. (2008) · The Journal of Nutrition · doi:10.3945/jn.108.095554 · Cited by 578 · cited 1×
“Although CGA is ingested by the oral route and absorbed by gastric and intestinal cells (Farah et al. 2008; Stalmach et al. 2010) and acts as a cytoprotective agent in several disease models (Krakauer 2002; Dos Santos et al.”
BackgroundKempf, K., Herder, C., Erlund, I., Kolb, H., Martin, S., Carstensen, M., Koenig, W., Sundvall, J., Bidel, S., Kuha, S., et al. (2010) · The American Journal of Clinical Nutrition · doi:10.3945/ajcn.2009.28548 · Cited by 364 · cited 1×
“2010) and acts as a cytoprotective agent in several disease models (Krakauer 2002; Dos Santos et al. 2006; Olmos et al. 2007; Zhang et al. 2010; Yonathan et al. 2006; Kempf et al. 2010), no information is currently available on its effects on gastric ulcer.”
BackgroundZhao, Z., Shin, H. S., Satsu, H., Totsuka, M., & Shimizu, M. (2008) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf073168d · Cited by 77 · cited 1×
“…Hoelzl et al. 2010), and the proposed mechanism of action involves its reductive and direct radical scavenger activity, in addition to activation of antioxidant enzymes and suppression of the transcription factors induced by reactive by reactive oxygen species (Zhao et al. 2008; Xu et al. 2010).”
Background
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Metadata
- Authors
- Shimoyama, A. T., Santin, J. R., Machado, I. D., de Oliveira e Silva, A. M., de Melo, I. L. P., Mancini-Filho, J., & Farsky, S. H. P.
- Venue
- Naunyn-Schmiedeberg's Archives of Pharmacology
- Published
- 2012-11-06
- Volume
- 386
- Issue
- 1
- Pages
- 5-14
- ISSN
- 0028-1298
- 1432-1912
- Cited by
- 90
- References
- 4
- Language
- en
- Licence
- www.springer.com/tdm (tdm)
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