The DOI matches its Crossref record; 69 of the 70 references it cites were found in a registry or an index.
Cue-elicited heart rate variability and attentional bias predict alcohol relapse following treatment
Open accessAbstract
Rationale Identification of malleable neurocognitive predictors of relapse among alcohol-dependent individuals is important for the optimization of health care delivery and clinical services. Objectives Given that alcohol cue-reactivity can predict relapse, we evaluated cue-elicited high-frequency heart rate variability (HFHRV) and alcohol attentional bias (AB) as potential relapse risk indices. Method Alcohol-dependent patients in long-term residential treatment who had participated in mindfulness-oriented therapy or an addiction support group completed a spatial cueing task as a measure of alcohol AB and an affect-modulated alcohol cue-reactivity protocol while HFHRV was assessed. Results Post-treatment HFHRV cue-reactivity and alcohol AB significantly predicted the occurrence and timing of relapse by 6-month follow-up, independent of treatment condition and after controlling for alcohol dependence severity. Alcohol-dependent patients who relapsed exhibited a significantly greater HFHRV reactivity to stress-primed alcohol cues than patients who did not relapse. Conclusions Cue-elicited HFHRV and alcohol AB can presage relapse and may therefore hold promise as prognostic indicators in clinical settings.
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“Contrary to their hypotheses, MORE did not significantly increase self-reported mindfulness, nor did it result in significant decrements in craving, but significantly reduced symptoms associated with chronic pain and prescription opioid misuse.”
From Mindfulness-Based Interventions for the Treatment of Substance and Behavioral Addictions: A Systematic Review (2018) · cites this paper as [30]
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“Two important candidate variables are alcohol cue-reactivity and alcohol attentional bias (Carter and Tiffany 1999; Fadardi and Cox 2006; Field and Cox 2008; Glautier and Drummond 1994; Stritzke et al. 2004; Townshend and Duka 2007).”
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Alcohol use disorder relapse factors: A systematic review.
Sliedrecht, W., de Waart, R., Witkiewitz, K., & Roozen, H. G. (2019) · Psychiatry Research · doi:10.1016/j.psychres.2019.05.038 · Cited by 358
Garland, E. L., Froeliger, B., Zeidan, F., Partin, K., & Howard, M. O. (2013) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2013.08.006 · Cited by 277
Self-citationSancho, M., De Gracia, M., Rodríguez, R. C., Mallorquí-Bagué, N., Sánchez-González, J., Trujols, J., Sánchez, I., Jiménez-Murcia, S., & Menchón, J. M. (2018) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2018.00095 · Cited by 224
“However, several trials showed other or different inclusion criteria: (1) residency at the treatment center or therapeutic community (20, 30, 37); (2) to be able to speak and read Persian (53); (3) to be 18–29 (40, 50), 18–20 (42), 14 or older (48), 18–40”
BackgroundMethodInfluentialWeiss, N. H., Sullivan, T. P., & Tull, M. T. (2015) · Current Opinion in Psychology · doi:10.1016/j.copsyc.2015.01.013 · Cited by 239
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Metadata
- Authors
- Garland, E. L., Franken, I. H. A., & Howard, M. O.
- Affiliations
- Florida State University (US)
- Erasmus University Rotterdam (NL)
- University of North Carolina at Chapel Hill (US)
- Corresponding author
- Garland, Eric L.
- Venue
- Psychopharmacology
- Published
- 2011-12-28
- Volume
- 222
- Issue
- 1
- Pages
- 17-26
- ISSN
- 0033-3158 (ISSN-L)
- 1432-2072
- PMC
- PMC3346884
- OpenAlex
- W2107603646
- Cited by
- 170
- References
- 70
- Citations by year
- 2026: 7 · 2025: 9 · 2024: 5 · 2023: 8 · 2022: 9 · 2021: 9 · 2020: 18 · 2019: 20 · 2018: 19 · 2017: 10 · 2016: 12 · 2015: 16 · 2014: 9 · 2013: 13 · 2012: 6
- FWCI
- 6.75
- Type
- journal article
- Language
- en
- Open access
- green
- europepmc.org
- Licence
- www.springer.com/tdm (tdm)
- Locations
- Psychopharmacology (publishedVersion)
- PubMed (publishedVersion)
- EUR Research Repository (Erasmus University Rotterdam) (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- EUR Research Repository (Erasmus University Rotterdam) (submittedVersion)
- Funders
- National Institute on Drug Abuse (R03DA032517)
- National Center for Complementary and Integrative Health (T32AT003378)
- Topics
- Health Sciences › Medicine › Epidemiology › Substance Abuse Treatment and Outcomes
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Heart Rate Variability and Autonomic Control
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neurotransmitter Receptor Influence on Behavior
- Keywords
- alcohol relapse, alcoholism, heart rate variability, attentional bias, alcohol cue reactivity, relapse risk prediction, addiction support groups, residential treatment, prognostic factors
- MeSH terms
- Adult, Alcoholism, Attention, Cues, Female, Follow-Up Studies, Heart Rate, Humans, Male, Recurrence, Self-Help Groups, Severity of Illness Index, Cognitive Behavioral Therapy, Treatment Outcome
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