Thiamine supplementation mood and cognitive functioning
Abstract
One hundred and twenty young adult females took either a placebo or 50 mg thiamine, each day for 2 months. Before and after taking the tablets, mood, memory and reaction times were monitored. An improvement in thiamine status was associated with reports of being more clearheaded, composed and energetic. The taking of thiamine had no influence on memory but reaction times were faster following supplementation. These influences took place in subjects whose thiamine status, according to the traditional criterion, was adequate.
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In an earlier study, high-dose thiamine (50 mg daily for 2 months) or placebo in 120 young adult women with adequate thiamine status improved thiamine status in treated subjects, associated with improved attention and a trend toward improved mood.
“An earlier study had assessed the effects of a high dose (50 mg daily for 2 months) of thiamine or placebo on 120 young adult women with adequate thiamine status at the study outset. Thiamine status, assessed via transketolase activation, was improved in treated subjects and this was associated with improved attention and a trend toward improved mood [197].”
From Vitamins and Minerals for Energy, Fatigue and Cognition: A Narrative Review of the Biochemical and Clinical Evidence (2020) · cites this paper as [197]
Cites
Concreteness, imagery, and meaningfulness values for 925 nouns.
Paivio, A., Yuille, J. C., & Madigan, S. A. (1968) · Journal of Experimental Psychology · doi:10.1037/h0025327 · Cited by 2,855 · see citing works
McNair, D. M. (1992) · Medical Entomology and Zoology · Cited by 2,527 · see citing works
The incidence of Wernicke's encephalopathy in Australia--a neuropathological study of 131 cases.
Harper, C. (1983) · Journal of Neurology Neurosurgery & Psychiatry · doi:10.1136/jnnp.46.7.593 · Cited by 337 · see citing works
EFFECT OF VITAMIN AND MINERAL SUPPLEMENTATION ON INTELLIGENCE OF A SAMPLE OF SCHOOLCHILDREN
Benton, D., & Roberts, G. (1988) · The Lancet · doi:10.1016/s0140-6736(88)92720-1 · Cited by 256 · see citing works
Self-citationCEREBRAL BERIBERI (WERNICKE'S ENCEPHALOPATHY)
de Wardener, H. E., & Lennox, B. (1947) · The Lancet · doi:10.1016/s0140-6736(47)91272-5 · Cited by 164 · see citing works
Smidt, L. J., Cremin, F. M., Grivetti, L. E., & Clifford, A. J. (1991) · Journal of Gerontology · doi:10.1093/geronj/46.1.m16 · Cited by 104 · see citing works
Controlled trial of vitamin-mineral supplementation: Effects of intelligence and performance
Schoenthaler, S. J., Amos, S. P., Eysenck, H. J., et al. (1991) · Personality and Individual Differences · doi:10.1016/0191-8869(91)90287-l · Cited by 101 · see citing works
Wernicke Encephalopathy Following Prolonged Intravenous Therapy
Nadel, A. M. (1976) · JAMA · doi:10.1001/jama.1976.03260480023023 · Cited by 74 · see citing works
The impact of long-term vitamin supplementation on cognitive functioning
Benton, D., Fordy, J., & Haller, J. (1995) · Psychopharmacology · doi:10.1007/bf02246104 · Cited by 66 · see citing works
Self-citationVitamin/mineral supplementation and intelligence
Crombie, I. K., Todman, J., McNeill, G., Florey, C. D., & Benton, D. (1990) · The Lancet · doi:10.1016/0140-6736(90)91694-6 · Cited by 56 · see citing works
Self-citationBenton, D., & Cook, R. (1991) · Personality and Individual Differences · doi:10.1016/0191-8869(91)90079-q · Cited by 56 · see citing works
Self-citationThe vitamin status of young British adults.
Benton, D., Haller, J., & Fordy, J. (1997) · PubMed · Cited by 53 · see citing works
Self-citationJp, V., Keller, H. E., Rettenmaier, R., et al. (1983) · PubMed · Cited by 50 · see citing works
Controlled trial of vitamin-mineral supplementation on intelligence and brain function
Schoenthaler, S. J., Amos, S. P., Doraz, W. E., Kelly, M. A., & Wakefield, J. (1991) · Personality and Individual Differences · doi:10.1016/0191-8869(91)90286-k · Cited by 37 · see citing works
The Wechsler subtests in mild organic brain damage associated with folate deficiency
Botez, M. I., Botez, T., & Maag, U. R. (1984) · Psychological Medicine · doi:10.1017/s0033291700003688 · Cited by 35 · see citing works
Vitamin-mineral supplements and intelligence
Benton, D. (1992) · Proceedings of The Nutrition Society · doi:10.1079/pns19920043 · Cited by 33 · see citing works
Self-citationFunctional Evaluation of Nutritional Status: Thiamine
Brin, M. (1967) · Elsevier eBooks · doi:10.1016/b978-0-12-048003-6.50015-2 · Cited by 16 · see citing works
Influence of Various Levels of Thiamine Intake on Physiologic Response . III. Reaction Time
Tuttle, W. W., Wilson, M., Daum, K., et al. (1949) · Journal of the American Dietetic Association · doi:10.1016/s0002-8223(21)29593-x · Cited by 12 · see citing works
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Kennedy, D. (2016) · Nutrients · doi:10.3390/nu8020068 · Cited by 1,055 · see citing works
Tardy, A.-L., Pouteau, E., Marquez, D., Yilmaz, C., & Scholey, A. (2020) · Nutrients · doi:10.3390/nu12010228 · Cited by 541 · see citing works
Effects of diet on behaviour and cognition in children
Bellisle, F. (2004) · British Journal of Nutrition · doi:10.1079/bjn20041171 · Cited by 301 · see citing works
Long, S.-J., & Benton, D. (2013) · Psychosomatic Medicine · doi:10.1097/psy.0b013e31827d5fbd · Cited by 110 · see citing works
- Authors
- Benton, D., Griffiths, R., & Haller, J.
- Affiliations
- Swansea University (GB)
- ORCID
- Benton, D.
- Venue
- Psychopharmacology
- Published
- 1997-01-13
- Volume
- 129
- Issue
- 1
- Pages
- 66-71
- ISSN
- 0033-3158 (ISSN-L)
- 1432-2072
- OpenAlex
- W1970131603
- Cited by
- 105
- References
- 18
- Citations by year
- 2025: 4 · 2024: 2 · 2023: 3 · 2022: 3 · 2021: 4 · 2020: 3 · 2019: 3 · 2018: 3 · 2017: 3 · 2016: 3 · 2015: 7 · 2014: 4 · 2013: 4 · 2012: 6
- FWCI
- 1.41
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- www.springer.com/tdm (tdm)
- Locations
- Psychopharmacology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Neurology › Alcoholism and Thiamine Deficiency
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Biochemistry › Biochemical Acid Research Studies
- Health Sciences › Medicine › Rheumatology › Folate and B Vitamins Research
- Keywords
- thiamine supplementation, mood, cognitive function, memory, reaction time, thiamine status, young adult women, thiamine
- MeSH terms
- Adult, Affect, Female, Humans, Memory, Reaction Time, Thiamine
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