Molecular Mechanisms of Vitamin D Action

Toll-Like Receptor Triggering of a Vitamin D-Mediated Human Antimicrobial Response

Liu, P. T., Stenger, S., Li, H., Wenzel, L., Tan, B. H., Krutzik, S. R., Ochoa, M. T., Schauber, J., Wu, K., Meinken, C., et al. (2006) · Science · doi:10.1126/science.1123933 · Cited by 3,924 · see citing works

Vitamin D

Norman, A. W. (1979) · Cited by 3,770 · see citing works

Endocrine regulation of energy metabolism by the skeleton

Lee, N. K., Sowa, H., Hinoi, E., Ferron, M., Ahn, J. D., Confavreux, C., Dacquin, R., Mee, P. J., McKee, M. D., Jung, D. Y., et al. (2007) · Cell · doi:10.1016/j.cell.2007.05.047 · Cited by 2,554 · see citing works

Nuclear Receptors and Lipid Physiology: Opening the X-Files

Chawla, A., Repa, J. J., Evans, R. M., & Mangelsdorf, D. J. (2001) · Science · doi:10.1126/science.294.5548.1866 · Cited by 2,085 · see citing works

FGF-23 Is a Potent Regulator of Vitamin D Metabolism and Phosphate Homeostasis

Shimada, T., Hasegawa, H., Yamazaki, Y., Muto, T., Hino, R., Takeuchi, Y., Fujita, T., Nakahara, K., Fukumoto, S., & Yamashita, T. (2004) · Journal of Bone and Mineral Research · doi:10.1359/jbmr.0301264 · Cited by 1,883 · see citing works

Vitamin effects on the immune system: Vitamins A and D take centre stage

Mora, J. R., Iwata, M., & von Andrian, U. H. (2008) · Nature Reviews Immunology · doi:10.1038/nri2378 · Cited by 1,559 · see citing works

Targeted ablation of Fgf23 demonstrates an essential physiological role of FGF23 in phosphate and vitamin D metabolism.

Shimada, T., Kakitani, M., Yamazaki, Y., Hasegawa, H., Takeuchi, Y., Fujita, T., Fukumoto, S., Tomizuka, K., & Yamashita, T. (2004) · Journal of Clinical Investigation · doi:10.1172/jci19081 · Cited by 1,503 · see citing works

Targeted ablation of Fgf23 demonstrates an essential physiological role of FGF23 in phosphate and vitamin D metabolism

Shimada, T., Kakitani, M., Yamazaki, Y., et al. (2004) · Journal of Clinical Investigation · doi:10.1172/jci200419081 · Cited by 1,368 · see citing works

β-Catenin Controls Hair Follicle Morphogenesis and Stem Cell Differentiation in the Skin

Huelsken, J., Vogel, R., Erdmann, B., Cotsarelis, G., & Birchmeier, W. (2001) · Cell · doi:10.1016/s0092-8674(01)00336-1 · Cited by 1,352 · see citing works

Vitamin D Receptor As an Intestinal Bile Acid Sensor

Makishima, M., Lu, T. T., Xie, W., Whitfield, G. K., Domoto, H., Evans, R. M., Haussler, M. R., & Mangelsdorf, D. J. (2002) · Science · doi:10.1126/science.1070477 · Cited by 1,176 · see citing works

The crystal structure of the nuclear receptor for vitamin D bound to its natural ligand

Rochel, N., Wurtz, J. M., Mitschler, A., Klaholz, B., & Moras, D. (2000) · Molecular Cell · doi:10.1016/s1097-2765(00)80413-x · Cited by 842 · see citing works

Regulation of Phosphate Homeostasis by PTH, Vitamin D, and FGF23

Bergwitz, C., & Jüppner, H. (2010) · Annual Review of Medicine · doi:10.1146/annurev.med.051308.111339 · Cited by 741 · see citing works

Vitamin D receptor (VDR)-mediated actions of 1α,25(OH)2vitamin D3: Genomic and non-genomic mechanisms

Haussler, M. R., Jurutka, P. W., Mizwicki, M. T., & Norman, A. W. (2011) · Best Practice & Research Clinical Endocrinology & Metabolism · doi:10.1016/j.beem.2011.05.010 · Cited by 688 · see citing works

Mutations inCYP24A1and Idiopathic Infantile Hypercalcemia

Schlingmann, K. P., Kaufmann, M., Weber, S., Irwin, A., Goos, C., John, U., Misselwitz, J., Klaus, G., Kuwertz-Bröking, E., Fehrenbach, H., et al. (2011) · New England Journal of Medicine · doi:10.1056/nejmoa1103864 · Cited by 682 · see citing works

Endocrine Regulation of Male Fertility by the Skeleton

Oury, F., Sumara, G., Sumara, O., Ferron, M., Chang, H., Smith, C. E., Hermo, L., Suarez, S., Roth, B. L., Ducy, P., et al. (2011) · Cell · doi:10.1016/j.cell.2011.02.004 · Cited by 628 · see citing works

The ß-Glucuronidase Klotho Hydrolyzes and Activates the TRPV5 Channel

Chang, Q., Hoefs, S. J. G., van der Kemp, A. W., Topala, C. N., Bindels, R. J. M., & Hoenderop, J. G. J. (2005) · Science · doi:10.1126/science.1114245 · Cited by 615 · see citing works

Duodenal calcium absorption in vitamin D receptor–knockout mice: Functional and molecular aspects

Cromphaut, S. J. V., Dewerchin, M. A., Hoenderop, J. G. J., Stockmans, I., Herck, E. V., Kato, S., Bindels, R. J. M., Collen, D., Carmeliet, P., Bouillon, R., et al. (2001) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.231474698 · Cited by 590 · see citing works

Cardiac hypertrophy in vitamin D receptor knockout mice: role of the systemic and cardiac renin-angiotensin systems

Xiang, W., Kong, J., Chen, S., Cao, L., Qiao, G., Zheng, W., Liu, W., Li, X., Gardner, D. G., & Li, Y. C. (2004) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00224.2004 · Cited by 570 · see citing works

Vitamin D Is Required for IFN-γ–Mediated Antimicrobial Activity of Human Macrophages

Fabri, M., Stenger, S., Shin, D., Yuk, J., Liu, P. T., Realegeno, S., Lee, H.-M., Krutzik, S., Schenk, M., Sieling, P., et al. (2011) · Science Translational Medicine · doi:10.1126/scitranslmed.3003045 · Cited by 520 · see citing works

1,25-Dihydroxyvitamin D3-induced differentiation in a human promyelocytic leukemia cell line (HL-60): receptor-mediated maturation to macrophage-like cells.

Mangelsdorf, D. J., Koeffler, H. P., Donaldson, C. A., Pike, J. W., & Haussler, M. R. (1984) · The Journal of Cell Biology · doi:10.1083/jcb.98.2.391 · Cited by 456 · see citing works

1,25-Dihydroxyvitamin D3 Ameliorates Th17 Autoimmunity via Transcriptional Modulation of Interleukin-17A

Joshi, S. S., Pantalena, L. C., Liu, X.-K., Gaffen, S., Liu, H., Rohowsky-Kochan, C., Ichiyama, K., Yoshimura, A., Steinman, L., Christakos, S., et al. (2011) · Molecular and Cellular Biology · doi:10.1128/mcb.05020-11 · Cited by 450 · see citing works

The FGF23–Klotho axis: endocrine regulation of phosphate homeostasis

Razzaque, M. S. (2009) · Nature Reviews Endocrinology · doi:10.1038/nrendo.2009.196 · Cited by 435 · see citing works

1α,25-Dihydroxyvitamin D3upregulates FGF23 gene expression in bone: the final link in a renal-gastrointestinal-skeletal axis that controls phosphate transport

Kolek, O. I., Hines, E. R., Jones, M. D., LeSueur, L., Lipko, M. A., Kiela, P. R., Collins, J. F., Haussler, M. R., & Ghishan, F. K. (2005) · American Journal of Physiology-Gastrointestinal and Liver Physiology · doi:10.1152/ajpgi.00243.2005 · Cited by 408 · see citing works

Targeted Inactivation of the 25-Hydroxyvitamin D3-1α-Hydroxylase Gene (CYP27B1) Creates an Animal Model of Pseudovitamin D-Deficiency Rickets*

Dardenne, O., Prud’homme, J., Arabian, A., Glorieux, F. H., & St‐Arnaud, R. (2001) · Endocrinology · doi:10.1210/endo.142.7.8281 · Cited by 404 · see citing works

Sequences in the human parathyroid hormone gene that bind the 1,25-dihydroxyvitamin D3 receptor and mediate transcriptional repression in response to 1,25-dihydroxyvitamin D3.

Demay, M. B., Kiernan, M. S., DeLuca, H. F., & Kronenberg, H. M. (1992) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.89.17.8097 · Cited by 403 · see citing works

The Vitamin D Receptor and the Syndrome of Hereditary 1,25-Dihydroxyvitamin D-Resistant Rickets

Malloy, P. J., Pike, J. W., & Feldman, D. (1999) · Endocrine Reviews · doi:10.1210/edrv.20.2.0359 · Cited by 393 · see citing works

Pregnane X Receptor (PXR), Constitutive Androstane Receptor (CAR), and Benzoate X Receptor (BXR) Define Three Pharmacologically Distinct Classes of Nuclear Receptors

Moore, L. B., Maglich, J. M., McKee, D. D., Wisely, B., Willson, T. M., Kliewer, S. A., Lambert, M. H., & Moore, J. T. (2002) · Molecular Endocrinology · doi:10.1210/mend.16.5.0828 · Cited by 356 · see citing works

Expression of CYP3A4, CYP2B6, andCYP2C9 Is Regulated by the Vitamin D Receptor Pathway in Primary Human Hepatocytes

Drocourt, L., Ourlin, J.-C., Pascussi, J., Maurel, P., & Vilarem, M. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m201323200 · Cited by 356 · see citing works

Vitamin D receptor: molecular signaling and actions of nutritional ligands in disease prevention

Haussler, M. R., Haussler, C. A., Bartik, L., Whitfield, G. K., Hsieh, J., Slater, S. A., & Jurutka, P. W. (2008) · Nutrition Reviews · doi:10.1111/j.1753-4887.2008.00093.x · Cited by 323 · see citing works

Vitamin D: Chemical, Biochemical and Clinical Endocrinology of Calcium Metabolism

Colston, K. W. (1983) · Biochemical Society Transactions · doi:10.1042/bst0110606a · Cited by 305 · see citing works

Skin abnormalities generated by temporally controlled RXRα mutations in mouse epidermis

Li, M., Indra, A. K., Warot, X. M., Brocard, J., Messaddeq, N., Kato, S., METZGER, D., & Chambon, P. (2000) · Nature · doi:10.1038/35036595 · Cited by 301 · see citing works

Positive and Negative Regulations of the Renal 25-Hydroxyvitamin D3 1α-Hydroxylase Gene by Parathyroid Hormone, Calcitonin, and 1α,25(OH)2D3 in Intact Animals*

Murayama, A., Takeyama, K., Kitanaka, S., Kodera, Y., Kawaguchi, Y., Hosoya, T., & Kato, S. (1999) · Endocrinology · doi:10.1210/endo.140.5.6691 · Cited by 296 · see citing works

Vitamin D decreases NFκB activity by increasing IκBα levels

Cohen, M., Shany, S., Tobvin, D., Chaimovitz, C., & Douvdevani, A. (2006) · Nephrology Dialysis Transplantation · doi:10.1093/ndt/gfi254 · Cited by 290 · see citing works

Vitamin D inhibits proliferation and profibrotic marker expression in hepatic stellate cells and decreases thioacetamide-induced liver fibrosis in rats

Abramovitch, S., Dahan-Bachar, L., Sharvit, E., Weisman, Y., Tov, A. B., Brazowski, E., & Reif, S. (2011) · Gut · doi:10.1136/gut.2010.234666 · Cited by 286 · see citing works

1,25(OH)2Vitamin D3 Stimulates Myogenic Differentiation by Inhibiting Cell Proliferation and Modulating the Expression of Promyogenic Growth Factors and Myostatin in C2C12 Skeletal Muscle Cells

Garcia, L. A., King, K. K., Ferrini, M. G., Norris, K. C., & Artaza, J. N. (2011) · Endocrinology · doi:10.1210/en.2011-0159 · Cited by 262 · see citing works

Active Intestinal Calcium Transport in the Absence of Transient Receptor Potential Vanilloid Type 6 and Calbindin-D9k

Benn, B. S., Ajibade, D. V., Porta, A., Dhawan, P., Hediger, M. A., Peng, J., Jiang, Y., Oh, G. T., Jeung, E., Lieben, L., et al. (2008) · Endocrinology · doi:10.1210/en.2007-1655 · Cited by 240 · see citing works

Regulation of Prostaglandin Metabolism by Calcitriol Attenuates Growth Stimulation in Prostate Cancer Cells

Moreno, J., Krishnan, A. V., Swami, S., Nonn, L., Peehl, D. M., & Feldman, D. (2005) · Cancer Research · doi:10.1158/0008-5472.can-05-1435 · Cited by 237 · see citing works

Vitamin D. Gene Regulation, Structure-Function Analysis and Clinical Application

Norman, A. W., Bouillon, R., & THOMASSET, M. (1991) · Cited by 234 · see citing works

Identification of a vitamin D-responsive element in the 5'-flanking region of the rat 25-hydroxyvitamin D3 24-hydroxylase gene.

Ohyama, Y., Ozono, K., Uchida, M., Shinki, T., Kato, S., Suda, T., Yamamoto, O., Noshiro, M., & Kato, Y. (1994) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(17)34094-2 · Cited by 231 · see citing works

CHROMOSOMAL RECEPTOR FOR A VITAMIN D METABOLITE

Haussler, M. R., & Norman, A. W. (1969) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.62.1.155 · Cited by 231 · see citing works

Novel Molecular Signaling and Classification of Human Clinically Nonfunctional Pituitary Adenomas Identified by Gene Expression Profiling and Proteomic Analyses

Moreno, C. S., Evans, C.-O., Zhan, X., Okor, M., Desiderio, D. M., & Oyesiku, N. M. (2005) · Cancer Research · doi:10.1158/0008-5472.can-05-0884 · Cited by 229 · see citing works

Induction of Intestinal Brush Border Alkaline Phosphatase by Vitamin D and Identity with Ca-ATPase

Haussler, M. R., Nagode, L. A., & Rasmussen, H. (1970) · Nature · doi:10.1038/2281199a0 · Cited by 226 · see citing works

The Human Transient Receptor Potential Vanilloid Type 6 Distal Promoter Contains Multiple Vitamin D Receptor Binding Sites that Mediate Activation by 1,25-Dihydroxyvitamin D3 in Intestinal Cells

Meyer, M. B., Watanuki, M., Kim, S., Shevde, N. K., & Pike, J. W. (2006) · Molecular Endocrinology · doi:10.1210/me.2006-0031 · Cited by 224 · see citing works

Activation of Receptor Activator of NF-κB Ligand Gene Expression by 1,25-Dihydroxyvitamin D3 Is Mediated through Multiple Long-Range Enhancers

Kim, S., Yamazaki, M., Zella, L. A., Shevde, N. K., & Pike, J. W. (2006) · Molecular and Cellular Biology · doi:10.1128/mcb.00353-06 · Cited by 223 · see citing works

Physical and Functional Interaction between the Vitamin D Receptor and Hairless Corepressor, Two Proteins Required for Hair Cycling

Hsieh, J., Sisk, J. M., Jurutka, P. W., Haussler, C. A., Slater, S. A., Haussler, M. R., & Thompson, C. C. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m304886200 · Cited by 213 · see citing works

DNA binding alters coactivator interaction surfaces of the intact VDR–RXR complex

Zhang, J., Chalmers, M. J., Stayrook, K. R., Burris, L. L., Wang, Y.-J., Busby, S. A., Pascal, B. D., Garcia-Ordoñez, R. D., Bruning, J. B., Istrate, M. A., et al. (2011) · Nature Structural & Molecular Biology · doi:10.1038/nsmb.2046 · Cited by 203 · see citing works

VDR/RXR and TCF4/β-Catenin Cistromes in Colonic Cells of Colorectal Tumor Origin: Impact on c-FOS and c-MYC Gene Expression

Meyer, M. B., Goetsch, P. D., & Pike, J. W. (2011) · Molecular Endocrinology · doi:10.1210/me.2011-1109 · Cited by 201 · see citing works

Vitamin D3 receptor ablation sensitizes skin to chemically induced tumorigenesis

Zinser, G. M. (2002) · Carcinogenesis · doi:10.1093/carcin/23.12.2103 · Cited by 199 · see citing works

Accelerated Fat Absorption in Intestinal Alkaline Phosphatase Knockout Mice

Narisawa, S., Huang, L., Iwasaki, A., Hasegawa, H., Alpers, D., & Millán, J. L. (2003) · Molecular and Cellular Biology · doi:10.1128/mcb.23.21.7525-7530.2003 · Cited by 199 · see citing works

Regulation of intestinal Na+-dependent phosphate co-transporters by a low-phosphate diet and 1,25-dihydroxyvitamin D3

Katai, K., Miyamoto, K., KISHIDA, S., Segawa, H., Nii, T., TANAKA, H., Tani, Y., Arai, H., Tatsumi, S., Morita, K., et al. (1999) · Biochemical Journal · doi:10.1042/bj3430705 · Cited by 194 · see citing works

Common architecture of nuclear receptor heterodimers on DNA direct repeat elements with different spacings

Rochel, N., Ciesielski, F., Godet, J., Momán, E., Roessle, M. W., Peluso‐Iltis, C., Moulin, M., Haertlein, M., Callow, P., Mély, Y., et al. (2011) · Nature Structural & Molecular Biology · doi:10.1038/nsmb.2054 · Cited by 193 · see citing works

Cytoplasmic and nuclear binding components for 1alpha25-dihydroxyvitamin D3 in chick parathyroid glands.

Brumbaugh, P. F., Hughes, M., & Haussler, M. R. (1975) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.72.12.4871 · Cited by 184 · see citing works

Klotho Gene Delivery Prevents the Progression of Spontaneous Hypertension and Renal Damage

Wang, Y., & Sun, Z. (2009) · Hypertension · doi:10.1161/hypertensionaha.109.134320 · Cited by 183 · see citing works

Altered Pharmacokinetics of 1α,25-Dihydroxyvitamin D3and 25-Hydroxyvitamin D3in the Blood and Tissues of the 25-Hydroxyvitamin D-24-Hydroxylase (Cyp24a1) Null Mouse

増田, 園., Byford, V., Arabian, A., Sakai, Y., Demay, M. B., St‐Arnaud, R., & Jones, G. (2004) · Endocrinology · doi:10.1210/en.2004-1116 · Cited by 182 · see citing works

The Vitamin D Receptor and the Syndrome of Hereditary 1,25-Dihydroxyvitamin D-Resistant Rickets

Malloy, P. J. (1999) · Endocrine Reviews · doi:10.1210/er.20.2.156 · Cited by 182 · see citing works

Drug-activated nuclear receptors CAR and PXR

Honkakoski, P., Sueyoshi, T., & Negishi, M. (2003) · Annals of Medicine · doi:10.1080/07853890310008224 · Cited by 180 · see citing works

1,25-Dihydroxyvitamin D3/VDR-mediated induction of FGF23 as well as transcriptional control of other bone anabolic and catabolic genes that orchestrate the regulation of phosphate and calcium mineral metabolism

Barthel, T. K., Mathern, D. R., Whitfield, G. K., Haussler, C. A., Hopper, H. A., Hsieh, J., Slater, S. A., Hsieh, G., Kaczmarska, M. J., Jurutka, P. W., et al. (2007) · The Journal of Steroid Biochemistry and Molecular Biology · doi:10.1016/j.jsbmb.2006.12.054 · Cited by 180 · see citing works

Filter assay for 1α,25-dihydroxyvitamin D3. Utilization of the hormone's target tissue chromatin receptor

Brumbaugh, P. F., Haussler, D. H., Bursac, K. M., & Haussler, M. R. (1974) · Biochemistry · doi:10.1021/bi00717a005 · Cited by 177 · see citing works

Characterization of a vitamin D receptor knockout mouse as a model of colorectal hyperproliferation and DNA damage

Kállay, E. (2001) · Carcinogenesis · doi:10.1093/carcin/22.9.1429 · Cited by 176 · see citing works

Vitamin D receptor controls expression of the anti-aging klotho gene in mouse and human renal cells

Forster, R. E., Jurutka, P. W., Hsieh, J., Haussler, C. A., Lowmiller, C. L., Kaneko, I., Haussler, M. R., & Whitfield, G. K. (2011) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2011.09.117 · Cited by 172 · see citing works

The nuclear vitamin D receptor controls the expression of genes encoding factors which feed the “Fountain of Youth” to mediate healthful aging

Haussler, M. R., Haussler, C. A., Whitfield, G. K., Hsieh, J., Thompson, P. D., Barthel, T. K., Bartik, L., Egan, J. B., Wu, Y., Kubicek, J. L., et al. (2010) · The Journal of Steroid Biochemistry and Molecular Biology · doi:10.1016/j.jsbmb.2010.03.019 · Cited by 171 · see citing works

Increased formation and decreased resorption of bone in mice with elevated vitamin D receptor in mature cells of the osteoblastic lineage

Gardiner, E. M., Baldock, P. A. J., Thomas, G. P., Sims, N. A., Briffa, K., Hollis, B. W., White, C., Sunn, K. L., Morrison, N. A., Walsh, W. R., et al. (2000) · The FASEB Journal · doi:10.1096/fj.99-1075com · Cited by 170 · see citing works

1,25-Dihydroxyvitamin D3Receptors and Hormonal Responses in Cloned Human Skeletal Muscle Cells*

Costa, E. M., Blau, H. M., & Feldman, D. I. (1986) · Endocrinology · doi:10.1210/endo-119-5-2214 · Cited by 166 · see citing works

Parathyroid Hormone Bone Anabolic Action Requires Cbfa1/Runx2-Dependent Signaling

Krishnan, V., Moore, T. L., Li, Y., Helvering, L. M., Frolik, C. A., Valasek, K. M., Ducy, P. F., & Geiser, A. G. (2003) · Molecular Endocrinology · doi:10.1210/me.2002-0225 · Cited by 162 · see citing works

Vitamin D3 receptor ablation alters mammary gland morphogenesis

Zinser, G. M., Packman, K. E., & Welsh, J. (2002) · Development · doi:10.1242/dev.129.13.3067 · Cited by 161 · see citing works

Inactivation of the vitamin D receptor enhances susceptibility of murine skin to UV-induced tumorigenesis

Ellison, T. I., Smith, M. K., Gilliam, A. C., & MacDonald, P. N. (2008) · Journal of Investigative Dermatology · doi:10.1038/jid.2008.131 · Cited by 159 · see citing works

Dehydroepiandrosterone Sulfotransferase Is a Target for Transcriptional Induction by the Vitamin D Receptor

Echchgadda, I., Song, C. S., Roy, A. K., & Chatterjee, B. (2004) · Molecular Pharmacology · doi:10.1124/mol.65.3.720 · Cited by 156 · see citing works

The role of vitamin D in the FGF23, klotho, and phosphate bone-kidney endocrine axis

Haussler, M. R., Whitfield, G. K., Kaneko, I., Forster, R. E., Saini, R. K., Hsieh, J., Haussler, C. A., & Jurutka, P. W. (2011) · Reviews in Endocrine and Metabolic Disorders · doi:10.1007/s11154-011-9199-8 · Cited by 151 · see citing works

Hairless triggers reactivation of hair growth by promoting Wnt signaling

Beaudoin, G. M. J., Sisk, J. M., Coulombe, P. A., & Thompson, C. C. (2005) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0507609102 · Cited by 149 · see citing works

Vitamin D Receptor: Key Roles in Bone Mineral Pathophysiology, Molecular Mechanism of Action, and Novel Nutritional Ligands

Jurutka, P. W., Bartik, L., Whitfield, G. K., Mathern, D. R., Barthel, T. K., Gurevich, M., Hsieh, J., Kaczmarska, M. J., Haussler, C. A., & Haussler, M. R. (2007) · Journal of Bone and Mineral Research · doi:10.1359/jbmr.07s216 · Cited by 148 · see citing works

Vitamin D receptor is essential for normal keratinocyte stem cell function

Cianferotti, L., Cox, M. K., Skorija, K., & Demay, M. B. (2007) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0702884104 · Cited by 148 · see citing works

Influence of 1,25-dihydroxyvitamin D3 on cultured osteogenic sarcoma cells: correlation with the 1,25-dihydroxyvitamin D3 receptor.

Dokoh, S., Donaldson, C. A., & Haussler, C. A. (1984) · PubMed · Cited by 144 · see citing works

Regulation of Type II Renal Na+-dependent Inorganic Phosphate Transporters by 1,25-Dihydroxyvitamin D3

Taketani, Y., Segawa, H., Chikamori, M., Morita, K., Tanaka, K., Kido, S., Yamamoto, H., Iemori, Y., Tatsumi, S., Tsugawa, N., et al. (1998) · Journal of Biological Chemistry · doi:10.1074/jbc.273.23.14575 · Cited by 138 · see citing works

KL1 Internal Repeat Mediates Klotho Tumor Suppressor Activities and Inhibits bFGF and IGF-I Signaling in Pancreatic Cancer

Abramovitz, L., Rubinek, T., Ligumsky, H., Bose, S., Barshack, I., Avivi, C., Kaufman, B., & Wolf, I. (2011) · Clinical Cancer Research · doi:10.1158/1078-0432.ccr-10-2749 · Cited by 134 · see citing works

Premature aging in vitamin D receptor mutant mice

Keisala, T., Minasyan, A., Lou, Y., Zou, J., Kalueff, A. V., Pyykkö, I. V., & Tuohimaa, P. (2009) · The Journal of Steroid Biochemistry and Molecular Biology · doi:10.1016/j.jsbmb.2009.03.007 · Cited by 132 · see citing works

Vitamin D and Prevention of Cancer — Ready for Prime Time?

Manson, J. E., Mayne, S. T., & Clinton, S. K. (2011) · New England Journal of Medicine · doi:10.1056/nejmp1102022 · Cited by 132 · see citing works

Liganded VDR induces CYP3A4 in small intestinal and colon cancer cells via DR3 and ER6 vitamin D responsive elements

Thompson, P. D., Jurutka, P. W., Whitfield, G. K., Myskowski, S., Eichhorst, K. R., Dominguez, C. E., Haussler, C. A., & Haussler, M. R. (2002) · Biochemical and Biophysical Research Communications · doi:10.1016/s0006-291x(02)02742-0 · Cited by 132 · see citing works

Characterization of Wise Protein and Its Molecular Mechanism to Interact with both Wnt and BMP Signals

Lintern, K., Guidato, S., Rowe, A., Saldanha, J. W., & Itasaki, N. (2009) · Journal of Biological Chemistry · doi:10.1074/jbc.m109.025478 · Cited by 122 · see citing works

Curcumin: a novel nutritionally derived ligand of the vitamin D receptor with implications for colon cancer chemoprevention

Bartik, L., Whitfield, G. K., Kaczmarska, M. J., Lowmiller, C. L., Moffet, E. W., Furmick, J. K., Hernandez, Z., Haussler, C. A., Haussler, M. R., & Jurutka, P. W. (2010) · The Journal of Nutritional Biochemistry · doi:10.1016/j.jnutbio.2009.09.012 · Cited by 121 · see citing works

Is Wnt signalling the final common pathway leading to bone formation?

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Cloning of a Functional Vitamin D Receptor from the Lamprey (Petromyzon marinus), an Ancient Vertebrate Lacking a Calcified Skeleton and Teeth

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Critical roles of intestinal epithelial vitamin D receptor signaling in controlling gut mucosal inflammation

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The Impact of Vitamin D on Skin Aging

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Vitamin D Actions on CD4+ T Cells in Autoimmune Disease

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Vitamin D in cancer chemoprevention

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Gut Epithelial Vitamin D Receptor Regulates Microbiota-Dependent Mucosal Inflammation by Suppressing Intestinal Epithelial Cell Apoptosis

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Vitamin D: do we get enough?

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MicroRNA-346 Mediates Tumor Necrosis Factor α–Induced Downregulation of Gut Epithelial Vitamin D Receptor in Inflammatory Bowel Diseases

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Benefits of Vitamins in the Treatment of Parkinson’s Disease

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Primary Vitamin D Target Genes of Human Monocytes

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Role of vitamin D and vitamin D receptor (VDR) in oral cancer

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Vitamin D Receptor Influences Intestinal Barriers in Health and Disease

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Vitamin D: Link between Osteoporosis, Obesity, and Diabetes?

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Vitamin D and Its Relationship with Obesity and Muscle

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Dairy intake and bone health across the lifespan: a systematic review and expert narrative

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Mineral Metabolism and Cortical Volumetric Bone Mineral Density in Childhood Chronic Kidney Disease

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Health Risks of Hypovitaminosis D: A Review of New Molecular Insights

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Serum 25-hydroxyvitamin D concentration is inversely associated with mucosal inflammation in patients with ulcerative colitis,

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Vitamin D Receptor Genotype, Vitamin D3 Supplementation, and Risk of Colorectal Adenomas

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Vitamin D treatment attenuates cardiac FGF23/FGFR4 signaling and hypertrophy in uremic rats

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Relationships between hyperinsulinaemia, magnesium, vitamin D, thrombosis and COVID-19: rationale for clinical management

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PTH, FGF-23, Klotho and Vitamin D as regulators of calcium and phosphorus: Genetics, epigenetics and beyond

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Vitamin D and lumisterol derivatives can act on liver X receptors (LXRs)

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Tumor Autonomous Effects of Vitamin D Deficiency Promote Breast Cancer Metastasis

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Vitamin D and Bone: A Story of Endocrine and Auto/Paracrine Action in Osteoblasts

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Probiotics in inflammatory bowel disease: microbial modulation and therapeutic prospects

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25-Hydroxyvitamin D and Total Cancer Incidence and Mortality: A Meta-Analysis of Prospective Cohort Studies

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Vitamin D Up-Regulates the Vitamin D Receptor by Protecting It from Proteasomal Degradation in Human CD4+ T Cells

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Vitamin D Receptor Gene Expression and Function in a South African Population: Ethnicity, Vitamin D and FokI

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SMURF2 regulates bone homeostasis by disrupting SMAD3 interaction with vitamin D receptor in osteoblasts

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Vitamin D and Its Receptor from a Structural Perspective

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Role of vitamin D receptor in the regulation of CYP3A gene expression

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Molecular Basis Underlying the Therapeutic Potential of Vitamin D for the Treatment of Depression and Anxiety

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Vitamin D in Neurological Diseases

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Vitamin D and estrogen synergy in Vdr-expressing CD4+ T cells is essential to induce Helios+FoxP3+ T cells and prevent autoimmune demyelinating disease

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Hip bone loss is attenuated with 1000 IU but not 400 IU daily vitamin D3: A 1-year double-blind RCT in postmenopausal women

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Clinical practice recommendations for treatment with active vitamin D analogues in children with chronic kidney disease Stages 2–5 and on dialysis

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Genomic Effects of the Vitamin D Receptor: Potentially the Link between Vitamin D, Immune Cells, and Multiple Sclerosis

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Lithocholic Acid Is a Vitamin D Receptor Ligand That Acts Preferentially in the Ileum

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Vitamin D, DNA methylation, and breast cancer

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Vitamin D insufficiency and insulin resistance in obese adolescents

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Obesity is associated with vitamin D deficiency in Danish children and adolescents

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The vitamin D receptor regulates mitochondrial function in C2C12 myoblasts

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Vitamin D receptor signaling improves Hutchinson-Gilford progeria syndrome cellular phenotypes

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Emphasizing the Health Benefits of Vitamin D for Those with Neurodevelopmental Disorders and Intellectual Disabilities

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Fine tuning of vitamin D receptor (VDR) activity by post-transcriptional and post-translational modifications

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Mobilising vitamin D from adipose tissue: The potential impact of exercise

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The role and mechanism of vitamin D‐mediated regulation of Treg/Th17 balance in recurrent pregnancy loss

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Vitamins: Key Role Players in Boosting Up Immune Response-A Mini Review

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Inhibition of Mouse Breast Tumor-Initiating Cells by Calcitriol and Dietary Vitamin D

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Urinary BPA and Phthalate Metabolite Concentrations and Plasma Vitamin D Levels in Pregnant Women: A Repeated Measures Analysis

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Role of Hypovitaminosis D in the Pathogenesis of Obesity-Induced Insulin Resistance

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Renal effects of growth hormone in health and in kidney disease

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Vitamin D in atherosclerosis and cardiovascular events.

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The fibroblast Tiam1-osteopontin pathway modulates breast cancer invasion and metastasis

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“Let there be light”: the role of vitamin D in the immune response to vaccines

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Vitamin D receptor mutations in patients with hereditary 1,25-dihydroxyvitamin D-resistant rickets

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Spotlight on vitamin D receptor, lipid metabolism and mitochondria: Some preliminary emerging issues

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Prevention of antipsychotic-induced hyperglycaemia by vitamin D: a data mining prediction followed by experimental exploration of the molecular mechanism

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Intranasal administration of vitamin D attenuates blood–brain barrier disruption through endogenous upregulation of osteopontin and activation of CD44/P-gp glycosylation signaling after subarachnoid hemorrhage in rats

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Vitamin D and MicroRNAs in Bone

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Vitamin D/vitamin D receptor axis regulates DNA repair during oncogene-induced senescence

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