Prevalence and patterns of antidepressant drug use during pregnancy
Open accessAbstract
Objective The aim of this study was to determine the extent and patterns of antidepressant use before, during and after pregnancy in a large population in The Netherlands.Methods Health care records and prescription data from one of the largest Dutch health insurance companies were analysed. The study cohort consisted of 29,005 women who had live births in the period between January 2000 and July 2003. Antidepressant drug use during a specified period was defined as there being a record of a prescription during that period.Results During the first trimester of pregnancy 2% of all pregnant women of the study cohort were found to have taken antidepressants; in the second and third trimesters, this figure had dropped to 1.8% of all pregnancies. Antidepressant use before as well as during pregnancy was almost twofold higher in women over 35 years of age than in those under 35 years. Almost 60% of the women who used antidepressants before pregnancy stopped taking them in the first trimester, and a smaller number stopped thereafter. Of all women using antidepressants during pregnancy, one third started this medication during gestation. In the 3 months following delivery, the prevalence of antidepressant use was the same as before pregnancy (2.9%). There was no shift to benzodiazepines in the group of women who stopped taking antidepressants during pregnancy. Although paroxetine and fluoxetine were the most frequently used antidepressants among the study group, all modern antidepressants were used.Conclusion A considerable number of women are being exposed to antidepressants throughout pregnancy up until delivery. One consequence of this is that their newborns need special care and supervision during the first days of life. However, women who stop taking the medication may risk a relapse of their illness, and this may also have a negative effect on the child.
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Only 2-8% of pregnant women are currently estimated to use antidepressants.
“Although pharmacological treatment is effective and can be safely utilized during pregnancy under medical supervision, only 2–8% of pregnant women are currently estimated to use antidepressants (23–26).”
From Acceptance, experiences, and needs of hospitalized pregnant women toward an electronic mindfulness-based intervention: A pilot mixed-methods study (2022) · cites this paper as [24]
Cites
Selective Serotonin-Reuptake Inhibitors and Risk of Persistent Pulmonary Hypertension of the Newborn
Chambers, C., Hernández–Dı́az, S., Marter, L. J. V., Werler, M. M., Louik, C., Jones, K. L., & Mitchell, A. A. (2006) · New England Journal of Medicine · doi:10.1056/nejmoa052744 · Cited by 877 · see citing works
Prescription drug use in pregnancy
Andrade, S. E., Gurwitz, J. H., Davis, R. L., Chan, K. A., Finkelstein, J. A., Fortman, K. K., McPhillips, H. A., Raebel, M. A., Roblin, D. W., Smith, D. H., et al. (2004) · American Journal of Obstetrics and Gynecology · doi:10.1016/j.ajog.2004.04.025 · Cited by 562 · see citing works
Nulman, I., ROVET, J. F., Stewart, D. E., Wolpin, J., Pace‐Asciak, P., Shuhaiber, S., & Koren, G. (2002) · American Journal of Psychiatry · doi:10.1176/appi.ajp.159.11.1889 · Cited by 440 · see citing works
Casper, R. C., Fleisher, B. E., Lee-Ancajas, J. C., Gilles, A. A., GAYLOR, E. E., DeBattista, A. M., & Hoyme, H. E. (2003) · The Journal of Pediatrics · doi:10.1067/mpd.2003.139 · Cited by 407 · see citing works
Sanz, E. J., Cuevas, C. D. L., Kiuru, A., Bate, A., & Edwards, R. (2005) · The Lancet · doi:10.1016/s0140-6736(05)17865-9 · Cited by 379 · see citing works
Maternal Selective Serotonin Reuptake Inhibitor Use During Pregnancy and Newborn Neurobehavior
Zeskind, P. S., & Stephens, L. E. (2004) · PEDIATRICS · doi:10.1542/peds.113.2.368 · Cited by 279 · see citing works
Validation studies of drug exposures in pregnant women
Czeizel, A. E., Petik, D., & Vargha, P. (2003) · Pharmacoepidemiology and Drug Safety · doi:10.1002/pds.766 · Cited by 155 · see citing works
Antidepressant drugs during pregnancy and infant congenital heart defect
Källén, B. A. J., & Olausson, P. O. (2006) · Reproductive Toxicology · doi:10.1016/j.reprotox.2005.11.006 · Cited by 143 · see citing works
Medication use during pregnancy: data from the Avon Longitudinal Study of Parents and Children
Headley, J., Northstone, K., Simmons, H., Golding, J., & and the ALSPAC Study Team (2004) · European Journal of Clinical Pharmacology · doi:10.1007/s00228-004-0775-7 · Cited by 142 · see citing works
Drug prescription in pregnancy: analysis of a large statutory sickness fund population
Egen‐Lappe, V., & Hasford, J. (2004) · European Journal of Clinical Pharmacology · doi:10.1007/s00228-004-0817-1 · Cited by 121 · see citing works
Assessment and treatment of depression during pregnancy: an update
Nonacs, R. M., & Cohen, L. S. (2003) · Psychiatric Clinics of North America · doi:10.1016/s0193-953x(03)00046-7 · Cited by 104 · see citing works
SSRIs in Pregnancy and Lactation
Gentile, S. (2005) · CNS Drugs · doi:10.2165/00023210-200519070-00004 · Cited by 94 · see citing works
Schirm, E., Meijer, W. M., Tobi, H., & den Berg, L. T. W. D. J. (2004) · European Journal of Obstetrics & Gynecology and Reproductive Biology · doi:10.1016/j.ejogrb.2003.10.024 · Cited by 73 · see citing works
Treatment with Selective Serotonin Reuptake Inhibitors in the Third Trimester of Pregnancy
Nordeng, H., & Spigset, O. (2005) · Drug Safety · doi:10.2165/00002018-200528070-00002 · Cited by 70 · see citing works
Olesen, C., Sørensen, H. T., den Berg, L. D. J., Olsen, J., Steffensen, F. H., & The Euromap Group (1999) · Acta Obstetricia Et Gynecologica Scandinavica · doi:10.1034/j.1600-0412.1999.780805.x · Cited by 61 · see citing works
Prescription of Drugs to Pregnant Women in France: the HIMAGE Study
Beyens, M., Guy, C., Ratrema, M., & Ollagnier, M. (2003) · Therapies · doi:10.2515/therapie:2003082 · Cited by 60 · see citing works
Paroxetine (Paxil) and congenital malformations
Williams, M. T. (2005) · Canadian Medical Association Journal · doi:10.1503/cmaj.051421 · Cited by 59 · see citing works
The length of uncomplicated human gestation.
Mittendorf, R., Williams, M. A., Berkey, C. S., & Cotter, P. F. (1990) · PubMed · Cited by 51 · see citing works
Hansen, D. G., Søndergaard, J., Vach, W., Gram, L. F., Rosholm, J., & Kragstrup, J. (2003) · European Journal of Clinical Pharmacology · doi:10.1007/s00228-003-0593-3 · Cited by 42 · see citing works
Schirm, E., Tobi, H., & den Berg, L. T. W. D. J. (2004) · Journal of Clinical Epidemiology · doi:10.1016/j.jclinepi.2002.12.001 · Cited by 42 · see citing works
AUSTRALIAN DRUG EVALUATION COMMITTEE
(1963) · The Medical Journal of Australia · doi:10.5694/j.1326-5377.1963.tb23502.x · Cited by 40 · see citing works
NTP‐CERHR Expert Panel Report on the reproductive and developmental toxicity of fluoxetine
Hines, R. N., Adams, J., Louis, G. M. B., Faber, W. D., Holson, J. F., Jacobson, S. W., Keszler, M., McMartin, K. E., Segraves, R. T., Singer, L. T., et al. (2004) · Birth Defects Research Part B Developmental and Reproductive Toxicology · doi:10.1002/bdrb.20014 · Cited by 33 · see citing works
Cohen, L. S., Altshuler, L. L., Stowe, Z. N., & Faraone, S. V. (2004) · Psychotherapy and Psychosomatics · doi:10.1159/000077745 · Cited by 31 · see citing works
Paroxetine withdrawal in a neonate with historical and laboratory confirmation
Jaiswal, S., Coombs, R. C., & Isbister, G. K. (2003) · European Journal of Pediatrics · doi:10.1007/s00431-003-1293-9 · Cited by 27 · see citing works
Fluoxetine use in early pregnancy
Källén, B. A. J. (2004) · Birth Defects Research Part B Developmental and Reproductive Toxicology · doi:10.1002/bdrb.20025 · Cited by 23 · see citing works
Do therapeutic indications of antidepressants change from one year to another?
Cuevas, C. D. L., & Sanz, E. J. (2003) · Pharmacoepidemiology and Drug Safety · doi:10.1002/pds.891 · Cited by 15 · see citing works
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New perspectives on the neurodevelopmental effects of SSRIs
Homberg, J. R., Schubert, D., & Gaspar, P. (2009) · Trends in Pharmacological Sciences · doi:10.1016/j.tips.2009.11.003 · Cited by 266 · see citing works
Antidepressant Exposure During Pregnancy and Congenital Malformations: Is There an Association?
Grigoriadis, S., VonderPorten, E. H., Mamisashvili, L., Roerecke, M., Rehm, J. T., Dennis, C., Koren, G., Steiner, M. S., Mousmanis, P., Cheung, A., et al. (2013) · The Journal of Clinical Psychiatry · doi:10.4088/jcp.12r07966 · Cited by 182 · see citing works
Rayen, I., van den Hove, D., Prickaerts, J., Steinbusch, H. W. M., & Pawluski, J. L. (2011) · PLoS ONE · doi:10.1371/journal.pone.0024003 · Cited by 175 · see citing works
Maternal psychological distress and fetal growth trajectories: The Generation R Study
Henrichs, J., Schenk, J. J., Roza, S. J., van den Berg, M. P., Schmidt, H. G., Steegers, E. A. P., Hofman, A., Jaddoe, V. W. V., Verhulst, F. C., & Tiemeier, H. (2010) · Psychological Medicine · doi:10.1017/s0033291709990894 · Cited by 165 · see citing works
Bakker, M. K., Kölling, P., Van Den Berg, P. B., De Walle, H. E. K., & De Jong van den Berg, L. T. W. (2008) · British Journal of Clinical Pharmacology · doi:10.1111/j.1365-2125.2007.03048.x · Cited by 158 · see citing works
Patterns of antidepressant medication use among pregnant women in a United States population
Alwan, S., Reefhuis, J., Rasmussen, S. A., Friedman, J. M., & Study, N. B. D. P. (2011) · The Journal of Clinical Pharmacology · doi:10.1177/0091270010373928 · Cited by 149 · see citing works
Fluoxetine administration to pregnant rats increases anxiety-related behavior in the offspring
Olivier, J. D. A., Vallès, A., van Heesch, F., Afrasiab-Middelman, A., Roelofs, J. J. P. M., Jonkers, M., Peeters, E. J., Korte-Bouws, G. A. H., Dederen, J., Kiliaan, A. J., et al. (2011) · Psychopharmacology · doi:10.1007/s00213-011-2299-z · Cited by 148 · see citing works
Jimenez‐Solem, E., Andersen, J. T., Petersen, M. A., Broedbaek, K., Jensen, J. K., Afzal, S., Gislason, G., Torp-Pedersen, C. T., & Poulsen, H. E. (2012) · BMJ Open · doi:10.1136/bmjopen-2012-001148 · Cited by 140 · see citing works
Ibañez, G. E., Charles, M.-A. A., Forhan, A., Magnin, G., Thiébaugeorges, O., Kaminski, M., & Saurel‐Cubizolles, M. (2012) · Early Human Development · doi:10.1016/j.earlhumdev.2012.01.014 · Cited by 131 · see citing works
The age-dependent effects of selective serotonin reuptake inhibitors in humans and rodents: a review
Olivier, J. D. A., Blom, T., Arentsen, T., & Homberg, J. R. (2011) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2010.09.013 · Cited by 131 · see citing works
Charlton, R., Jordan, S., Pierini, A., Garne, E., Neville, A., Hansen, A., Gini, R., Thayer, D., Tingay, K., Puccini, A., et al. (2015) · BJOG: An International Journal of Obstetrics & Gynaecology · doi:10.1111/1471-0528.13143 · Cited by 121 · see citing works
Prevalence of Antidepressant Use during Pregnancy in Denmark, a Nation-Wide Cohort Study
Jimenez-Solem, E., Andersen, J. T., Petersen, M., Broedbaek, K., Andersen, N. L., Torp-Pedersen, C., & Poulsen, H. E. (2013) · PLoS ONE · doi:10.1371/journal.pone.0063034 · Cited by 119 · see citing works
Calderon-Margalit, R., Qiu, C., Ornoy, A., Siscovick, D. S., & Williams, M. A. (2009) · American Journal of Obstetrics and Gynecology · doi:10.1016/j.ajog.2009.06.061 · Cited by 115 · see citing works
Perinatal depression: treatment options and dilemmas
Pearlstein, T. B. (2008) · Journal of Psychiatry and Neuroscience · doi:10.1139/jpn.0829 · Cited by 113 · see citing works
Kornum (2010) · Clinical Epidemiology · doi:10.2147/clep.s9256 · Cited by 112 · see citing works
Olivier, J. D. A., Åkerud, H., Kaihola, H., Pawluski, J. L., Skalkidou, A., Högberg, U., & Poromaa, I. S. (2013) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2013.00073 · Cited by 108 · see citing works
Zoëga, H., Kieler, H., Nørgaard, M., Furu, K., Valdimarsdóttir, U. A., Brandt, L., & Haglund, B. (2015) · PLoS ONE · doi:10.1371/journal.pone.0144474 · Cited by 108 · see citing works
The neurodevelopmental effects of serotonin: A behavioural perspective
Kepser, L.-J., & Homberg, J. R. (2014) · Behavioural Brain Research · doi:10.1016/j.bbr.2014.05.022 · Cited by 103 · see citing works
Bérard, A., Iessa, N., Chaabane, S., Muanda, F., Boukhris, T., & Zhao, J.-P. (2016) · British Journal of Clinical Pharmacology · doi:10.1111/bcp.12849 · Cited by 86 · see citing works
Lee, L. (2009) · Neurotoxicity Research · doi:10.1007/s12640-009-9022-4 · Cited by 100 · see citing works
Placental Transfer of Antidepressant Medications: Implications for Postnatal Adaptation Syndrome
Ewing, G., Tatarchuk, Y., Appleby, D. H., Schwartz, N., & Kim, D. (2015) · Clinical Pharmacokinetics · doi:10.1007/s40262-014-0233-3 · Cited by 97 · see citing works
Pawluski, J. L., Rayen, I., Niessen, N., Kristensen, S., van Donkelaar, E. L., Balthazart, J., Steinbusch, H. W. M., & Charlier, T. D. (2012) · Neuroscience · doi:10.1016/j.neuroscience.2012.06.034 · Cited by 97 · see citing works
Selective Serotonin Reuptake Inhibitors Affect Neurobehavioral Development in the Human Fetus
Mulder, E. J. H., Ververs, T. F., de Heus, R., & Visser, G. H. A. (2011) · Neuropsychopharmacology · doi:10.1038/npp.2011.67 · Cited by 96 · see citing works
Self-citationEl Marroun, H., White, T., Verhulst, F. C., & Tiemeier, H. (2014) · European Child & Adolescent Psychiatry · doi:10.1007/s00787-014-0558-3 · Cited by 92 · see citing works
Tuccori, M., Testi, A., Antonioli, L., Fornai, M., Montagnani, S., Ghisu, N., Colucci, R., Corona, T., Blandizzi, C., & Tacca, M. D. (2009) · Clinical Therapeutics · doi:10.1016/j.clinthera.2009.07.009 · Cited by 95 · see citing works
Effect of Cytochrome P450 2D6 Genotype on Maternal Paroxetine Plasma Concentrations during Pregnancy
Ververs, T. F., Voorbij, H. A. M., Zwarts, P., Belitser, S. V., Egberts, T. C. G., Visser, G. H. A., & Schobben, A. F. A. M. (2009) · Clinical Pharmacokinetics · doi:10.2165/11318050-000000000-00000 · Cited by 95 · see citing works
Self-citationColvin, L., Slack-Smith, L. M., Stanley, F. J., & Bower, C. I. (2011) · Birth Defects Research Part A Clinical and Molecular Teratology · doi:10.1002/bdra.20773 · Cited by 93 · see citing works
Maternal use of SSRIs, SNRIs and NaSSAs: practical recommendations during pregnancy and lactation
Sie, S. D., WENNINK, J. M. B., van Driel, J. J., Winkel, A. T., Boer, K., Casteelen, G., & van Weissenbruch, M. M. (2012) · Archives of Disease in Childhood Fetal & Neonatal · doi:10.1136/archdischild-2011-214239 · Cited by 88 · see citing works
Wemakor, A., Casson, K., Garne, E., Bakker, M., Addor, M., Arriola, L., Gatt, M., Khoshnood, B., Klungsøyr, K., Nelen, V., et al. (2015) · European Journal of Epidemiology · doi:10.1007/s10654-015-0065-y · Cited by 73 · see citing works
Pawluski, J. L., Brain, U. M., Underhill, C., Hammond, G. L., & Oberlander, T. F. (2011) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2011.11.011 · Cited by 81 · see citing works
Neurodevelopmental effects of prenatal exposure to psychotropic medications
Gentile, S. (2010) · Depression and Anxiety · doi:10.1002/da.20706 · Cited by 76 · see citing works
Behavioural effects of fetal antidepressant exposure in a Norwegian cohort of discordant siblings
Brandlistuen, R. E., Ystrøm, E., Eberhard‐Gran, M., Nulman, I., Koren, G., & Nordeng, H. (2015) · International Journal of Epidemiology · doi:10.1093/ije/dyv030 · Cited by 72 · see citing works
Edvinsson, Å., Bränn, E., Hellgren, C., Freyhult, E., White, R. A., Kamali‐Moghaddam, M., Olivier, J., Bergquist, J., Boström, A. E. D., Schiöth, H. B., et al. (2017) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2017.02.027 · Cited by 62 · see citing works
Complex Challenges in Treating Depression During Pregnancy
Chaudron, L. H. (2013) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2012.12040440 · Cited by 60 · see citing works
Eryılmaz, G., Hızlısayar, G., Özten, E., Gogcegoz-Gul, I., Yorbik, O., Işiten, N., & Bağcı, E. (2015) · Neuromodulation (Malden, Mass.) · doi:10.1111/ner.12231 · Cited by 49 · see citing works
Kinast, K., Peeters, D., Kolk, S. M., Schubert, D., & Homberg, J. R. (2013) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2013.00072 · Cited by 57 · see citing works
Does Paroxetine Cause Cardiac Malformations?
O’Brien, L., Einarson, T. R., Sarkar, M., Einarson, A., & Koren, G. (2008) · Journal of Obstetrics and Gynaecology Canada · doi:10.1016/s1701-2163(16)32918-8 · Cited by 56 · see citing works
Gemmel, M., Rayen, I., van Donkelaar, E. L., Loftus, T., Steinbusch, H. W. M., Kokras, N., Dalla, C., & Pawluski, J. L. (2016) · Neuroscience · doi:10.1016/j.neuroscience.2016.03.068 · Cited by 56 · see citing works
Margulis, A. V., Kang, E. M., & Hammad, T. A. (2013) · Maternal and Child Health Journal · doi:10.1007/s10995-013-1419-2 · Cited by 55 · see citing works
Knaepen, L., Rayen, I., Charlier, T. D., Fillet, M., Houbart, V., van Kleef, M., Steinbusch, H. W. M., Patijn, J., Tibboel, D., Joosten, E. A. J., et al. (2013) · PLoS ONE · doi:10.1371/journal.pone.0057608 · Cited by 55 · see citing works
Kingston, D. E., McDonald, S., Tough, S., Austin, M., Hegadoren, K., & Lasiuk, G. C. (2014) · BMC Pregnancy and Childbirth · doi:10.1186/1471-2393-14-67 · Cited by 54 · see citing works
Nationwide register‐based surveillance system on drugs and pregnancy in Finland 1996–2006
Artama, M., Gissler, M., Malm, H. T., & Ritvanen, A. (2011) · Pharmacoepidemiology and Drug Safety · doi:10.1002/pds.2159 · Cited by 53 · see citing works
Gentile, S. (2010) · CNS Spectrums · doi:10.1017/s1092852900027449 · Cited by 53 · see citing works
Women with bipolar disorder and pregnancy: factors influencing their decision-making
Dolman, C., Jones, I. R., & Howard, L. M. (2016) · BJPsych Open · doi:10.1192/bjpo.bp.116.003079 · Cited by 51 · see citing works
de Vries, N. K. S., van der Veere, C. N., Reijneveld, S. A., & Bos, A. F. (2013) · PLoS ONE · doi:10.1371/journal.pone.0064654 · Cited by 51 · see citing works
Weng, S.-C., Chang, J., Yeh, M., Wang, S.-M., & Chen, Y. (2016) · Scientific Reports · doi:10.1038/srep25770 · Cited by 50 · see citing works
Munk‐Olsen, T., Gasse, C., & Laursen, T. M. (2011) · Acta Psychiatrica Scandinavica · doi:10.1111/j.1600-0447.2011.01784.x · Cited by 48 · see citing works
Gemmel, M., Rayen, I., Lotus, T., van Donkelaar, E. L., Steinbusch, H. W. M., Lacalle, S. D., Kokras, N., Dalla, C., & Pawluski, J. L. (2015) · Developmental Psychobiology · doi:10.1002/dev.21372 · Cited by 48 · see citing works
Shen, Z., Gao, S., Li, S. X., Zhang, T., Liu, C., Lv, H., Zhang, Y., Gong, T., Xu, X., Ji, C., et al. (2016) · British Journal of Clinical Pharmacology · doi:10.1111/bcp.13161 · Cited by 48 · see citing works
Gentile, S., & Bellantuono, C. (2009) · The Journal of Clinical Psychiatry · doi:10.4088/jcp.08r04468 · Cited by 46 · see citing works
Lindqvist, P. G., Nasiell, J., Gustafsson, L. L., & Nordström, L. (2014) · Journal of Thrombosis and Haemostasis · doi:10.1111/jth.12757 · Cited by 45 · see citing works
Prenatal Antidepressant Exposure and Offspring Brain Morphologic Trajectory
Koc, D., Tiemeier, H., Stricker, B. H., Muetzel, R. L., Hillegers, M., & El Marroun, H. (2023) · JAMA Psychiatry · doi:10.1001/jamapsychiatry.2023.3161 · Cited by 44 · see citing works
The use of antidepressant medication in pregnancy
Ray, S. L., & Stowe, Z. N. (2013) · Best Practice & Research Clinical Obstetrics & Gynaecology · doi:10.1016/j.bpobgyn.2013.09.005 · Cited by 44 · see citing works
Serotonin reuptake inhibitors in pregnancy and the risk of major malformations: a systematic review
Bellantuono, C., Migliarese, G., & Gentile, S. (2007) · Human Psychopharmacology Clinical and Experimental · doi:10.1002/hup.836 · Cited by 44 · see citing works
Different patterns of depressive symptoms during pregnancy
Truijens, S. E. M., Spek, V., van Son, M. J. M., Guid Oei, S., & Pop, V. J. M. (2017) · Archives of Women's Mental Health · doi:10.1007/s00737-017-0738-5 · Cited by 43 · see citing works
Prady, S. L., Pickett, K. E., Gilbody, S. M., Petherick, E., Mason, D., Sheldon, T., & Wright, J. (2016) · BMC Psychiatry · doi:10.1186/s12888-016-0805-x · Cited by 42 · see citing works
Psychotherapeutic Treatments for Depression During Pregnancy
Genovez, M., Vanderkruik, R. C., Lemon, E. L., & Dimidjian, S. (2018) · Clinical Obstetrics & Gynecology · doi:10.1097/grf.0000000000000388 · Cited by 40 · see citing works
Andersen, S. L., & Navalta, C. P. (2011) · Journal of Child Psychology and Psychiatry · doi:10.1111/j.1469-7610.2011.02376.x · Cited by 38 · see citing works
Cantarutti, A., Merlino, L. G., Giaquinto, C., & Corrao, G. (2017) · Pharmacoepidemiology and Drug Safety · doi:10.1002/pds.4242 · Cited by 37 · see citing works
Medication Errors in Obstetrics
Kfuri, T. A., Morlock, L., Hicks, R. W., & Shore, A. D. (2008) · Clinics in Perinatology · doi:10.1016/j.clp.2007.11.015 · Cited by 37 · see citing works
Hannerfors, A.-K., Hellgren, C., Schijven, D., Iliadis, S. I., Comasco, E., Skalkidou, A., Olivier, J. D. A., & Poromaa, I. S. (2015) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2015.04.009 · Cited by 36 · see citing works
Prenatal Antidepressant Exposure: Clinical and Preclinical Findings
Bourke, C. H., Stowe, Z. N., & Owens, M. J. (2014) · Pharmacological Reviews · doi:10.1124/pr.111.005207 · Cited by 36 · see citing works
Zhang, T., Gao, S., Shen, Z., Li, D., Liu, C., Lv, H., Zhang, Y., Gong, T., Xu, X. P., Ji, C., et al. (2017) · Scientific Reports · doi:10.1038/srep43085 · Cited by 32 · see citing works
Molenaar, N. M., Lambregtse-van den Berg, M. P., & Bonsel, G. J. (2020) · Archives of Women's Mental Health · doi:10.1007/s00737-019-0951-5 · Cited by 30 · see citing works
Tuccori, M., Montagnani, S., Testi, A., Ruggiero, E., Mantarro, S., Scollo, C., Pergola, A., Fornai, M., Antonioli, L., Colucci, R., et al. (2010) · Postgraduate Medicine · doi:10.3810/pgm.2010.07.2175 · Cited by 31 · see citing works
Antidepressants during pregnancy and postpartum hemorrhage: a systematic review
Bruning, A. H. L., Heller, H. M., Kieviet, N., Bakker, P., de Groot, C. J. M., Dolman, K. M., & Honig, A. (2015) · European Journal of Obstetrics & Gynecology and Reproductive Biology · doi:10.1016/j.ejogrb.2015.03.022 · Cited by 31 · see citing works
Wald, J., Henningsson, A., Hanze, E., Hoffmann, E. C., Li, H., Colquhoun, H., & Deligiannidis, K. M. (2022) · Clinical Pharmacokinetics · doi:10.1007/s40262-022-01155-w · Cited by 31 · see citing works
Psychotropic prescription practices in east Asia: looking back and peering ahead
Tan, C., Shinfuku, N., & Sim, K. (2008) · Current Opinion in Psychiatry · doi:10.1097/yco.0b013e32830e6dc4 · Cited by 30 · see citing works
Ververs, T. F., van Dijk, L., Yousofi, S., Schobben, F., & Visser, G. H. A. (2009) · BMC Health Services Research · doi:10.1186/1472-6963-9-119 · Cited by 30 · see citing works
Self-citationCocaine use during pregnancy assessed by hair analysis in a Canary Islands cohort
Joya, X., Gómez‐Culebras, M., Callejón, A. C., Fríguls, B., Puig, C., Gómez, S. O., Morini, L., García‐Algar, Ó., & Vall, O. (2012) · BMC Pregnancy and Childbirth · doi:10.1186/1471-2393-12-2 · Cited by 29 · see citing works
Bais, B., Kamperman, A. M., van der Zwaag, M. D., Dieleman, G. C., Harmsen van der Vliet-Torij, H. W., Bijma, H. H., Lieverse, R., Hoogendijk, W. J. G., & Lambregtse-van den Berg, M. P. (2016) · BMC Psychiatry · doi:10.1186/s12888-016-1092-2 · Cited by 28 · see citing works
Liao, C., & Lee, L. (2011) · Toxicology Letters · doi:10.1016/j.toxlet.2011.09.028 · Cited by 28 · see citing works
de Oliveira, W. M., de Sá, I. R., de Torres, S. M., de Morais, R. N., Martino‐Andrade, A. J., Maia, F. C. L., Tenório, B. M., & da Silva, V. A. (2013) · Systems Biology in Reproductive Medicine · doi:10.3109/19396368.2013.796021 · Cited by 28 · see citing works
Molenaar, N. M., Brouwer, M. E., Bockting, C., Bonsel, G. J., van der Veere, C. N., Torij, H. W., Hoogendijk, W. J. G., Duvekot, J. J., Burger, H., & den Berg, M. P. L. (2016) · BMC Psychiatry · doi:10.1186/s12888-016-0752-6 · Cited by 27 · see citing works
Galbally, M., Ryan, J. L., van IJzendoorn, M. H., Watson, S., Spigset, O., Lappas, M., Saffery, R., de Kloet, E. R., & Lewis, A. J. (2018) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2018.01.004 · Cited by 27 · see citing works
Child developmental outcomes in preschool children following antidepressant exposure in pregnancy
Galbally, M., Lewis, A. J., & Buist, A. (2015) · Australian & New Zealand Journal of Psychiatry · doi:10.1177/0004867415569800 · Cited by 27 · see citing works
Obstetric outcomes in pregnant women with and without depression: population-based comparison
Huang, H., Sung, F.-C., Chen, P., Chang, C. Y.-Y., Muo, C., Shiue, H.-S., Huang, J.-P., Li, T., Tzeng, Y., & Wu, S. (2017) · Scientific Reports · doi:10.1038/s41598-017-14266-3 · Cited by 26 · see citing works
Should Antidepressants be Avoided in Pregnancy?
Besag, F., & Vasey, M. J. (2022) · Drug Safety · doi:10.1007/s40264-022-01257-1 · Cited by 25 · see citing works
Houwing, D. J., Heijkoop, R., Olivier, J. D. A., & Snoeren, E. M. S. (2019) · Neuropharmacology · doi:10.1016/j.neuropharm.2019.03.037 · Cited by 25 · see citing works
Zakiyah, N., ter Heijne, L. F., Bos, J., Hak, E., Postma, M. J., & Schuiling‐Veninga, C. C. M. (2018) · BMC Pregnancy and Childbirth · doi:10.1186/s12884-018-1825-y · Cited by 24 · see citing works
Trevizol, A., & Blumberger, D. (2019) · Clinical pharmacology and therapy · doi:10.1002/cpt.1550 · Cited by 22 · see citing works
Pregnancy Exposure to Serotonin Reuptake Inhibitors and the Risk of Spontaneous Abortions
Gentile, S. (2008) · CNS Spectrums · doi:10.1017/s1092852900014012 · Cited by 24 · see citing works
Bais, B., Kamperman, A. M., Bijma, H. H., Hoogendijk, W. J., Souman, J. L., Knijff, E., & Lambregtse-van den Berg, M. P. (2020) · BMJ Open · doi:10.1136/bmjopen-2020-038030 · Cited by 24 · see citing works
Davis, K., & Dimidjian, S. (2012) · Clinical Psychology Science and Practice · doi:10.1111/j.1468-2850.2012.01273.x · Cited by 24 · see citing works
Nijenhuis, C. M., ter Horst, P. G. J., den Berg, L. T. W. D. J., & Wilffert, B. (2011) · British Journal of Clinical Pharmacology · doi:10.1111/j.1365-2125.2011.04075.x · Cited by 24 · see citing works
Galbally, M., Watson, S., Teti, D. M., & Lewis, A. J. (2018) · Journal of Affective Disorders · doi:10.1016/j.jad.2018.05.025 · Cited by 23 · see citing works
Treatment of nonpsychotic major depression during pregnancy: patient safety and challenges
EPSTEIN, R. A., Moore, K. M., & Bobo, W. V. (2014) · Drug Healthcare and Patient Safety · doi:10.2147/dhps.s43308 · Cited by 22 · see citing works
Perinatal maternal stress and serotonin signaling: Effects on pain sensitivity in offspring
Knaepen, L., Pawluski, J. L., Patijn, J., van Kleef, M., Tibboel, D., & Joosten, E. A. J. (2013) · Developmental Psychobiology · doi:10.1002/dev.21184 · Cited by 23 · see citing works
van der Veere, C. N., de Vries, N. K. S., Braeckel, K. N. J. A. V., & Bos, A. F. (2020) · Early Human Development · doi:10.1016/j.earlhumdev.2020.105075 · Cited by 21 · see citing works
Different patterns of attentional bias in antenatal and postpartum depression
Edvinsson, Å., Skalkidou, A., Hellgren, C., Gingnell, M., Ekselius, L., Willebrand, M., & Poromaa, I. S. (2017) · Brain and Behavior · doi:10.1002/brb3.844 · Cited by 21 · see citing works
Grieb, Z. A., & Ragan, C. M. (2019) · European Neuropsychopharmacology · doi:10.1016/j.euroneuro.2019.07.239 · Cited by 21 · see citing works
LC–MS-MS Method for the Determination of Antidepressants and Benzodiazepines in Meconium
López-Rabuñal, Á., Lendoiro, E., Concheiro, M., López‐Rivadulla, M., Cruz, A., & de-Castro-Ríos, A. (2020) · Journal of Analytical Toxicology · doi:10.1093/jat/bkaa012 · Cited by 21 · see citing works
Neonatal Outcomes in Maternal Depression in Relation to Intrauterine Drug Exposure
Corti, S., Pileri, P., Mazzocco, M. I., Mandò, C., Moscatiello, A. F., Cattaneo, D., Cheli, S., Baldelli, S., Pogliani, L., Clementi, E., et al. (2019) · Frontiers in Pediatrics · doi:10.3389/fped.2019.00309 · Cited by 21 · see citing works
Gur, T., Kim, D. R., & Epperson, C. N. (2013) · Psychopharmacology · doi:10.1007/s00213-013-3115-8 · Cited by 20 · see citing works
Sousa-Ferreira, L., Aveleira, C. A., Botelho, M., Álvaro, A. R., de Almeida, L. P., & Cavadas, C. (2014) · PLoS ONE · doi:10.1371/journal.pone.0088917 · Cited by 19 · see citing works
Bellissima, V., Visser, G. H. A., Ververs, T. F., van Bel, F., Termote, J. U. M., van der Heide, M., Florio, P., Volti, G. L., & Gazzolo, D. (2011) · The Journal of Maternal-Fetal & Neonatal Medicine · doi:10.3109/14767058.2011.604931 · Cited by 19 · see citing works
Self-citationBreastfeeding, Antidepressants, and Depression in the Mercy Pregnancy and Emotional Well-Being Study
Galbally, M., Watson, S., Ball, H. L., & Lewis, A. J. (2018) · Journal of Human Lactation · doi:10.1177/0890334418758658 · Cited by 19 · see citing works
Intermittent theta burst stimulation for major depression during pregnancy
Trevizol, A. P., Vigod, S. N., Daskalakis, Z. J., Vila‐Rodriguez, F., Downar, J. H., & Blumberger, D. M. (2019) · Brain stimulation · doi:10.1016/j.brs.2019.01.003 · Cited by 19 · see citing works
Trajectories of antidepressant drugs during pregnancy: A cohort study from a community‐based sample
Cabaillot, A., Bourset, A. C., Mulliez, A., Delorme, J., Orri, M., Vicard‐Olagne, M., Zénut, M., Tournier, M., Gallot, D., Authier, N., et al. (2020) · British Journal of Clinical Pharmacology · doi:10.1111/bcp.14449 · Cited by 19 · see citing works
Lack of Tryptophan Hydroxylase-1 in Mice Results in Gait Abnormalities
Suidan, G. L., Duerschmied, D., Dillon, G. M., VanderHorst, V., Hampton, T., Wong, S. L., Voorhees, J. R., & Wagner, D. D. (2013) · PLoS ONE · doi:10.1371/journal.pone.0059032 · Cited by 18 · see citing works
- Authors
- Ververs, T., Kaasenbrood, H., Visser, G., Schobben, F., de Jong-van den Berg, L., & Egberts, T.
- Affiliations
- University Medical Center Utrecht (NL)
- Corresponding author
- Egberts, Toine
- Venue
- European Journal of Clinical Pharmacology
- Published
- 2006-08-08
- Volume
- 62
- Issue
- 10
- Pages
- 863-870
- ISSN
- 0031-6970 (ISSN-L)
- 1432-1041
- OpenAlex
- W2166028098
- Cited by
- 174
- References
- 26
- Citations by year
- 2026: 1 · 2025: 2 · 2024: 3 · 2023: 4 · 2022: 8 · 2021: 3 · 2020: 9 · 2019: 10 · 2018: 8 · 2017: 8 · 2016: 11 · 2015: 11 · 2014: 15 · 2013: 23 · 2012: 10
- FWCI
- 8.33
- Type
- journal article
- Language
- en
- Open access
- green
- dspace.library.uu.nl
- Licence
- other-oa
- www.springer.com/tdm (tdm)
- Locations
- European Journal of Clinical Pharmacology (publishedVersion)
- PubMed (publishedVersion)
- Utrecht University Repository (Utrecht University) (submittedVersion, other-oa)
- University of Groningen research database (University of Groningen / Centre for Information Technology) (submittedVersion)
- Topics
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Pregnancy and Medication Impact
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Maternal Mental Health During Pregnancy and Postpartum
- Health Sciences › Medicine › Pediatrics, Perinatology and Child Health › Prenatal Substance Exposure Effects
- Keywords
- antidepressant use, pregnancy, maternal mental health, antidepressant discontinuation, first trimester, postpartum depression, paroxetine, fluoxetine, benzodiazepines, maternal age, prescribing patterns, neonatal care
- MeSH terms
- Adolescent, Adult, Age Factors, Antidepressive Agents, Benzodiazepines, Depressive Disorder, Drug Therapy, Combination, Female, Fluoxetine, Humans, Insurance, Pharmaceutical Services, Netherlands, Pregnancy, Pregnancy Complications, Pregnancy Trimesters, Drug Prescriptions, Time Factors, Prevalence, Databases, Factual, Paroxetine, Drug Utilization Review
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