Cited by 99Probiotics and Fermented FoodsEssential Oils and Antimicrobial ActivityAntimicrobial Peptides and Activities

Current state of purification, isolation and analysis of bacteriocins produced by lactic acid bacteria

Kaškonienė, Vilma, Stankevičius, Mantas, Bimbiraitė-Survilienė, Kristina, Naujokaitytė, Gintarė, Šernienė, Loreta, Mulkytė, Kristina, Malakauskas, Mindaugas, Maruška, Audrius·2017·Applied Microbiology and Biotechnology

Abstract

The scientific interest for the search of natural means of microbial inhibitors has not faded for several years. A search of natural antibiotics, so-called bacteriocins which are produced by lactic acid bacteria (LAB), gains a huge attention of the scientists in the last century, in order to reduce the usage of synthetic food additives. Pure bacteriocins with wide spectra of antibacterial activity are promising among the natural biopreservatives. The usage of bacteriocin(s) producing LAB as starter culture for the fermentation of some food products, in order to increase their shelf-life, when synthetic preservatives are not allowable, is also possible. There are a lot of studies focusing on the isolation of new bacteriocins from traditional fermented food, dairy products and other foods or sometimes even from unusual non-food matrices. Bacteriocins producing bacteria have been isolated from different sources with the different antibacterial activity against food-borne microorganisms. This review covers the classification of bacteriocins, diversity of sources of bacteriocin(s) producing LAB, antibacterial spectra of isolated bacteriocins and analytical methods for the bacteriocin purification and analysis within the last 15 years.

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Crossref · 10.1007/s00253-017-8088-9

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125 of 125 references verified0 citation errors · 0 not checkable

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  • Bacteriocins are peptides with antimicrobial activity, synthesized by bacteria in ribosomes; these peptides often exhibit a narrow inhibitory spectrum and inhibit taxonomically-close bacteria.

    “Bacteriocins are peptides with antimicrobial activity, synthesized by bacteria in ribosomes. These peptides often exhibit a narrow inhibitory spectrum and inhibit taxonomically-close bacteria [143,183,184,185].”
  • Nisin A and pediocin are the only bacteriocins commercially available at present.

    “The only bacteriocins commercially available at present are nisin A, produced by Lc. lactis, and pediocin, produced by P. acidilactici [51,185].”

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Authors
Kaškonienė, V., Stankevičius, M., Bimbiraitė-Survilienė, K., Naujokaitytė, G., Šernienė, L., Mulkytė, K., Malakauskas, M., & Maruška, A.
Affiliations
  • Vytautas Magnus University (LT)
  • Lithuanian University of Health Sciences (LT)
Corresponding author
Kaškonienė, Vilma
Venue
Applied Microbiology and Biotechnology
Published
2017-01-09
Volume
101
Issue
4
Pages
1323-1335
ISSN
  • 0175-7598 (ISSN-L)
  • 1432-0614
OpenAlex
W2570650478
Cited by
99
References
126
Citations by year
2026: 3 · 2025: 5 · 2024: 15 · 2023: 8 · 2022: 12 · 2021: 20 · 2020: 9 · 2019: 5 · 2018: 15 · 2017: 7
FWCI
1.07
Type
journal article
Language
en
Open access
closed
Locations
  • Applied Microbiology and Biotechnology (publishedVersion)
  • PubMed (publishedVersion)
  • Lithuanian University of Health Sciences (submittedVersion)
  • Vytautas Magnus University (submittedVersion)
Funders
Research Council of Lithuania (MIP-063/2015 (BIOLACTIS))
Topics
  • Life Sciences › Agricultural and Biological Sciences › Food Science › Probiotics and Fermented Foods
  • Life Sciences › Agricultural and Biological Sciences › Food Science › Essential Oils and Antimicrobial Activity
  • Life Sciences › Immunology and Microbiology › Microbiology › Antimicrobial Peptides and Activities
Keywords
bacteriocins, lactic acid bacteria, bacteriocin purification, antibacterial activity, biopreservatives, starter cultures, fermented foods, dairy products, foodborne pathogens, natural antimicrobials, bacteriocin classification
MeSH terms
Bacteria, Bacteriocins, Food Microbiology, Lactic Acid

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