Cited by 73Reproductive tract infections researchAntifungal resistance and susceptibilitySexual function and dysfunction studies

Influence of recurrent vulvovaginal candidiasis on quality of life issues

Fukazawa, Eiko I., Witkin, Steven S., Robial, Renata, Vinagre, João G., Baracat, Edmund C., Linhares, Iara M.·2019·Archives of Gynecology and Obstetrics

Abstract

Purpose More than 370 million women will experience recurrent vulvovaginal candidiasis (RVVC) during their lifetime. However, RVVC is often trivialized as clinically insignificant and not worthy of research funding. We evaluated the influence of RVVC on the quality of life in affected women.Methods The validated World Health Organization Quality of Life Abbreviated Assessment (WHOQOL-Bref) questionnaire was administered to 100 women with RVVC and to 101 epidemiologically matched women with no history of vulvovaginal candidiasis. RVVC was defined as at least four episodes of clinical and culture-positive vaginal candidiasis within a 1 year period. Data were analyzed by Chi square, Student t test and analysis of variance. Internal consistency of responses to questions was evaluated by Cronbach alpha.Results The Cronbach alpha coefficient was > 0.80 for responses to generalized questions and > 0.65 for answers to more specific questions, indicating substantial internal consistency. Perception of quality of life and satisfaction with their health was greatly reduced in the RVVC group (p < 0.001). Diminished responses to physical and psychological well-being were also reported by women with RVVC (p < 0.001). Various aspects of social relations including sexual activity were similarly reduced (p < 0.001) as were satisfaction with issues such as home environment, financial resources and employment (p < 0.001).Conclusion RVVC affects multiple aspects of a woman's well-being. Women with this condition deserve serious attention from clinicians and research into susceptibility, prevention and treatment of this infection deserves much greater emphasis.

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Crossref · 10.1007/s00404-019-05228-3

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Authors
Fukazawa, E. I., Witkin, S. S., Robial, R., Vinagre, J. G., Baracat, E. C., & Linhares, I. M.
Affiliations
Universidade de São Paulo (BR)
Corresponding author
Witkin, Steven S.
Venue
Archives of Gynecology and Obstetrics
Published
2019-07-03
Volume
300
Issue
3
Pages
647-650
ISSN
  • 0003-9128 (ISSN-L)
  • 0932-0067
  • 1432-0711
OpenAlex
W2955194836
Cited by
69
References
15
Citations by year
2026: 5 · 2025: 9 · 2024: 10 · 2023: 9 · 2022: 10 · 2021: 19 · 2020: 6 · 2019: 1
FWCI
6.66
Type
journal article
Language
en
Open access
closed
Locations
  • Archives of Gynecology and Obstetrics (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Life Sciences › Immunology and Microbiology › Microbiology › Reproductive tract infections research
  • Health Sciences › Medicine › Infectious Diseases › Antifungal resistance and susceptibility
  • Health Sciences › Medicine › Psychiatry and Mental health › Sexual function and dysfunction studies
Keywords
recurrent vulvovaginal candidiasis, quality of life, WHOQOL-BREF, physical well-being, psychological well-being, interpersonal relationships, sexual activity, health satisfaction, women's health
MeSH terms
Adult, Candida, Candidiasis, Vulvovaginal, Female, Health Status, Humans, Quality of Life, Surveys and Questionnaires, Recurrence, Sexual Behavior, Case-Control Studies

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