The DOI matches its Crossref record; 129 of the 129 references it cites were found in a registry or an index.
Neurological symptoms, manifestations, and complications associated with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and coronavirus disease 19 (COVID-19)
Open accessAbstract
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), a novel coronavirus, is responsible for the outbreak of coronavirus disease 19 (COVID-19) and was first identified in Wuhan, China in December 2019. It is evident that the COVID-19 pandemic has become a challenging world issue. Although most COVID-19 patients primarily develop respiratory symptoms, an increasing number of neurological symptoms and manifestations associated with COVID-19 have been observed. In this narrative review, we elaborate on proposed neurotropic mechanisms and various neurological symptoms, manifestations, and complications of COVID-19 reported in the present literature. For this purpose, a review of all current published literature (studies, case reports, case series, reviews, editorials, and other articles) was conducted and neurological sequelae of COVID-19 were summarized. Essential and common neurological symptoms including gustatory and olfactory dysfunctions, myalgia, headache, altered mental status, confusion, delirium, and dizziness are presented separately in sections. Moreover, neurological manifestations and complications that are of great concern such as stroke, cerebral (sinus) venous thrombosis, seizures, meningoencephalitis, Guillain–Barré syndrome, Miller Fisher syndrome, acute myelitis, and posterior reversible encephalopathy syndrome (PRES) are also addressed systematically. Future studies that examine the impact of neurological symptoms and manifestations on the course of the disease are needed to further clarify and assess the link between neurological complications and the clinical outcome of patients with COVID-19. To limit long-term consequences, it is crucial that healthcare professionals can early detect possible neurological symptoms and are well versed in the increasingly common neurological manifestations and complications of COVID-19.
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Cites
Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China
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Cited by
Wu, X., Yang, H., He, S., Xia, T., Chen, D., Zhou, Y., Liu, J., Liu, M., & Sun, Z. (2022) · Frontiers in Immunology · doi:10.3389/fimmu.2022.872542 · Cited by 73
Viral sepsis: diagnosis, clinical features, pathogenesis, and clinical considerations
Xu, J.-Q., Zhang, W.-Y., Fu, J.-J., Fang, X.-Z., Gao, C.-G., Li, C., Yao, L., Li, Q.-L., Yang, X.-B., Ren, L.-H., et al. (2024) · Military Medical Research · doi:10.1186/s40779-024-00581-0 · Cited by 37
Could the fibromyalgia syndrome be triggered or enhanced by COVID-19?
Fialho, M. F. P., Brum, E. S., & Oliveira, S. M. (2023) · Inflammopharmacology · doi:10.1007/s10787-023-01160-w · Cited by 33
Post-COVID-19 Parkinsonism and Parkinson’s Disease Pathogenesis: The Exosomal Cargo Hypothesis
Mysiris, D. S., Vavougios, G. D., Karamichali, E., Papoutsopoulou, S., Stavrou, V. T., Papayianni, E., Boutlas, S., Mavridis, T., Foka, P., Zarogiannis, S. G., et al. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23179739 · Cited by 25
How viral infections cause neuronal dysfunction: a focus on the role of microglia and astrocytes
Hosseini, S., & Korte, M. (2023) · Biochemical Society Transactions · doi:10.1042/bst20220771 · Cited by 17
Metadata
- Authors
- Harapan, B. N., & Yoo, H. J.
- Venue
- Journal of Neurology
- Published
- 2021-01-23
- Volume
- 268
- Issue
- 9
- Pages
- 3059-3071
- ISSN
- 0012-1037 (ISSN-L)
- 0340-5354
- 1432-1459
- OpenAlex
- W3122166825
- Cited by
- 359
- References
- 129
- FWCI
- 33.49
- Type
- journal article
- Language
- en
- Open access
- hybrid
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- Harapan, B. N., & Yoo, H. J. (2021). Neurological symptoms, manifestations, and complications associated with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and coronavirus disease 19 (COVID-19). Journal of Neurology. https://doi.org/10.1007/s00415-021-10406-y
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