CoChat
Sign Up
Cited by 245

The DOI matches its Crossref record; 4 of the 4 references it cites were found in a registry or an index.

Transplacental exposure of neonates to perfluorooctanesulfonate and perfluorooctanoate: a pilot study

Midasch, O., Drexler, H., Hart, N., Beckmann, M. W., Angerer, J.·2007·International Archives of Occupational and Environmental Health
DOI 10.1007/s00420-006-0165-9
Open this paper in CoChat — free account

Abstract

Objectives Perfluorooctanesulfonate (PFOS) and perfluorooctanoate (PFOA) can be released of perfluorinated compounds by biotic and/or metabolic decomposition. Due to their ubiquitous occurrence, persistence and bioaccumulative properties they can be found in blood of the general population all over the world. In animal studies PFOS and PFOA provoked cancer and showed developmental toxic potential besides other adverse health effects. On the basis of the comparison of maternal and umbilical cord plasma sample pairs we wanted to examine whether infants are exposed to PFOS and PFOA via their mothers' blood. Methods We determined PFOS and PFOA in 11 plasma samples of mothers and the 11 corresponding cord plasma samples of neonates. An analytical method based on plasma protein precipitation followed by HPLC with MS/MS-detection was employed. As internal standards we used 1,2,3,4-(13)C(4)-PFOS and 1,2-(13)C(2)-PFOA. Results We found PFOS and PFOA in every plasma sample analysed. In maternal plasma samples PFOS concentrations were consistently higher compared to those of the related cord plasma samples (median: 13.0 microg/l vs. 7.3 microg/l). In the case of PFOA we observed only minor differences between PFOA concentrations within the analysed sample pairs (median: 2.6 microg/l vs. 3.4 microg/l for maternal and cord plasma samples, respectively). Discussion For both substances a crossing of the placental barrier could be shown. For PFOS we observed a decrease from maternal to cord…

Overview

Integrity signals

Registry

Crossref · 10.1007/s00420-006-0165-9

Cites

4 of 4 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Verification

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Citations

Cites

Research works printed but not linked: 36

  1. Butenhoff JL, Kennedy GL Jr, Frame SR, O’Connor JC, York RG (2004) The reproductive toxicology of ammonium perfluorooctanoate (APFO) in the rat. Toxicology 196(1–2):95–116 · DOI · Paper page
  2. Butenhoff JL, York R, Seacat A, Luebker D (2002) Perfluorooctanesulfonate induced perinatal mortality in rat pups is associated with a steep dose-response. Toxicologist 66:25
  3. Calafat AM, Needham LL, Kuklenyik Z, Reidy JA, Tully JS, Aguilar-Villalobos M, Naeher LP (2005) Perfluorinated chemicals in selected residents of the American continent. Chemosphere 63(3):490–496 · DOI
  4. Cochran TE, Good W (1974) The distribution of immunoglobulins and albumin between maternal and cord serum at delivery. J Obstet Gynaecol Br Commonw 81:980–987 · DOI
  5. Fromme H, Midasch O, Twardella D, Angerer J, Boehmer S, Liebl B (2006) Occurrence of perfluorinated substances in an adult German population in southern Bavaria. Int Arch Occup Environ Health (in press) · DOI
  6. Gauthier SA, Mabury SA (2005) Aqueous photolysis of 8:2 fluorotelomer alcohol. Environ Toxicol Chem 24(8):1837–1846 · DOI
  7. Giesy JP, Kannan K (2002) Perfluorochemical surfactants in the environment. Environ Sci Technol 36(7):146A–152A · DOI
  8. Grasty RC, Bjork JA, Wallace KB, Lau CS, Rogers JM (2005) Effects of prenatal perfluorooctane sulfonate (PFOS) exposure on lung maturation in the perinatal rat. Birth Defects Res B Dev Reprod Toxicol 74(5):405–416 · DOI
  9. Grasty RC, Grey BE, Lau CS, Rogers JM (2003) Prenatal window of susceptibility to perfluorooctane sulfonate-induced neonatal mortality in the Sprague-Dawley rat. Birth Defects Res B Dev Reprod Toxicol 68(6):465–471 · DOI
  10. Guruge KS, Taniyasu S, Yamashita N, Wijeratna S, Mohotti KM, Seneviratne HR, Kannan K, Yamanaka N, Miyazaki S (2005) Perfluorinated organic compounds in human blood serum and seminal plasma: a study of urban and rural tea worker populations in Sri Lanka. J Environ Monit 7(4):371–377 · DOI
  11. Han X, Snow TA, Kemper RA, Jepson GW (2003) Binding of perfluorooctanoic acid to rat and human plasma proteins. Chem Res Toxicol 16(6):775–781 · DOI
  12. Harada K, Saito N, Inoue K, Yoshinaga T, Watanabe T, Sasaki S, Kamiyama S, Koizumi A (2004) The influence of time, sex and geographic factors on levels of perfluorooctane sulfonate and perfluorooctanoate in human serum over the last 25 years. J Occup Health 46(2):141–147 · DOI
  13. Hill MD, Abramson FP (1988) The significance of plasma protein binding on the fetal/maternal distribution of drugs at steady-state. Clin Pharmacokinet 14(3):156–170 · DOI
  14. Hinderliter PM, Mylchreest E, Gannon SA, Butenhoff JL, Kennedy GL Jr (2005) Perfluorooctanoate: placental and lactational transport pharmacokinetics in rats. Toxicology 211(1–2):139–148 · DOI
  15. Inoue K, Okada F, Ito R, Kato S, Sasaki S, Nakajima S, Uno A, Saijo Y, Sata F, Yoshimura Y, Kishi R, Nakazawa H (2004) Perfluorooctane sulfonate (PFOS) and related perfluorinated compounds in human maternal and cord blood samples: assessment of PFOS exposure in a susceptible population during pregnancy. Environ Health Perspect 112(11):1204–1207 · DOI
  16. Jin Y, Liu X, Li T, Qin H (2004) Status of perfluorochemicals in adult serum and umbilical blood in Shenyang. Wei Sheng Yan Jiu 33(4):481–483
  17. Kannan K, Koistinen J, Beckmen K, Evans T, Gorzelany JF, Hansen KJ, Jones PD, Helle E, Nyman M, Giesy JP (2001) Accumulation of perfluorooctane sulfonate in marine mammals. Environ Sci Technol 35(8):1593–1598 · DOI
  18. Kärrman A (2004) Perfluoroalkylated compounds in whole blood and plasma from the Swedish population. Organohalogen Compd 66:4058–4062
  19. Krauer B, Dayer P, Anner R (1984) Changes in serum albumin and alpha 1-acid glycoprotein concentrations during pregnancy: an analysis of fetal-maternal pairs. Br J Obstet Gynaecol 91(9):875–881 · DOI
  20. Kubwabo C, Vais N, Benoit FM (2004) A pilot study on the determination of perfluorooctanesulfonate and other perfluorinated compounds in blood of Canadians. J Environ Monit 6(6):540–545 · DOI
  21. Kuklenyik Z, Reich JA, Tully JS, Needham LL, Calafat AM (2004) Automated solid-phase extraction and measurement of perfluorinated organic acids and amides in human serum and milk. Environ Sci Technol 38(13):3698–3704 · DOI
  22. Lau C, Butenhoff JL, Rogers JM (2004) The developmental toxicity of perfluoroalkyl acids and their derivatives. Toxicol Appl Pharmacol 198(2):231–241 · DOI · Paper page
  23. Lau C, Thibodeaux JR, Hanson RG, Narotsky MG, Rogers JM, Lindstrom AB, Strynar MJ (2006) Effects of perfluorooctanoic acid exposure during pregnancy in the mouse. Toxicol Sci 90(2):510–518 · DOI
  24. Lau C, Thibodeaux JR, Hanson RG, Rogers JM, Grey BE, Stanton ME, Butenhoff JL, Stevenson LA (2003) Exposure to perfluorooctane sulfonate during pregnancy in rat and mouse. II: postnatal evaluation. Toxicol Sci 74(2):382–392 · DOI · Paper page
  25. Luebker DJ, Case MT, York RG, Moore JA, Hansen KJ, Butenhoff JL (2005a) Two-generation reproduction and cross-foster studies of perfluorooctanesulfonate (PFOS) in rats. Toxicology 215(1–2):126–148 · DOI
  26. Luebker DJ, York RG, Hansen KJ, Moore JA, Butenhoff JL (2005b) Neonatal mortality from in utero exposure to perfluorooctanesulfonate (PFOS) in Sprague-Dawley rats: dose-response, and biochemical and pharamacokinetic parameters. Toxicology 215(1–2):149–169 · DOI
  27. Martin JW, Mabury SA, O’Brien PJ (2005) Metabolic products and pathways of fluorotelomer alcohols in isolated rat hepatocytes. Chem Biol Interact 155(3):165–180 · DOI
  28. Midasch O, Schettgen T, Angerer J (2006) Pilot study on the perfluorooctanesulfonate and perfluorooctanoate exposure of the German general population. Int J Hyg Environ Health 209(6):489–496 · DOI
  29. Olsen G, Ehresman D, Froehlich J, Burris J, Butenhoff J (2005) Evaluation of the half-life (t1/2) of elimination of perfluorooctanesulfonate (PFOS), perfluorohexanesulfonate (PFHS) and perfluorooctanoate (PFOA) from human serum. Presentation at the 9th FLUOROS, International symposium on fluorinated alkyl organics in the environment, Toronto, Canada, Abstract book available at: http://www.chem.utoronto.ca/symposium/fluoros/Flourosabstractbook.pdf
  30. Olsen GW, Church TR, Larson EB, van Belle G, Lundberg JK, Hansen KJ, Burris JM, Mandel JH, Zobel LR (2004) Serum concentrations of perfluorooctanesulfonate and other fluorochemicals in an elderly population from Seattle, Washington. Chemosphere 54(11):1599–1611 · DOI
  31. Olsen GW, Church TR, Miller JP, Burris JM, Hansen KJ, Lundberg JK, Armitage JB, Herron RM, Medhdizadehkashi Z, Nobiletti JB, O’Neill EM, Mandel JH, Zobel LR (2003a) Perfluorooctanesulfonate and other fluorochemicals in the serum of American red cross adult blood donors. Environ Health Perspect 111(16):1892–1901 · DOI
  32. Olsen GW, Hansen KJ, Stevenson LA, Burris JM, Mandel JH (2003b) Human donor liver and serum concentrations of perfluorooctanesulfonate and other perfluorochemicals. Environ Sci Technol 37(5):888–891 · DOI
  33. Thibodeaux JR, Hanson RG, Rogers JM, Grey BE, Barbee BD, Richards JH, Butenhoff JL, Stevenson LA, Lau C (2003) Exposure to perfluorooctane sulfonate during pregnancy in rat and mouse. I: maternal and prenatal evaluations. Toxicol Sci 74(2):369–381 · DOI · Paper page
  34. Wallington TJ, Hurley MD, Xia J, Wuebbles DJ, Sillman S, Ito A, Penner JE, Ellis DA, Martin J, Mabury SA, Nielsen OJ, Sulbaek Andersen MP (2006) Formation of C7F15COOH (PFOA) and other perfluorocarboxylic acids during the atmospheric oxidation of 8:2 fluorotelomer alcohol. Environ Sci Technol 40(3):924–930 · DOI
  35. Xu L, Krenitsky DM, Seacat AM, Butenhoff JL, Anders MW (2004) Biotransformation of N-ethyl-N-(2-hydroxyethyl) perfluorooctanesulfonamide by rat liver microsomes, cytosol, and slices and by expressed rat and human cytochromes P450. Chem Res Toxicol 17(6):767–775 · DOI
  36. Yeung LW, So MK, Jiang G, Taniyasu S, Yamashita N, Song M, Wu Y, Li J, Giesy JP, Guruge KS, Lam PK (2006) Perfluorooctanesulfonate and related fluorochemicals in human blood samples from China. Environ Sci Technol 40(3):715–720 · DOI

Cited by

Sorted by citations

See all 245

Metadata

Authors
Midasch, O., Drexler, H., Hart, N., Beckmann, M. W., & Angerer, J.
Venue
International Archives of Occupational and Environmental Health
Publisher
Springer Science and Business Media LLC
Published
2007-01-12
Volume
80
Issue
7
Pages
643-648
ISSN
  • 0340-0131
  • 1432-1246
DOI
10.1007/s00420-006-0165-9
Cited by
245
References
4
Language
en
Licence

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review