Adaptation rate of 6-sulfatoxymelatonin and cognitive performance in offshore fleet shift workers: a field study
Abstract
Purpose To determine the total phase delay and adaptation rate of 6-sulfatoxymelatonin (aMT6s) on subjective and objective sleep quality and cognitive performance after 7 days of working night shifts (1800-0600 hours). The subjects studied were offshore fleet workers (N = 7).Methods Seven days of urine samples were collected to determine the total phase delay and adaptation rate of aMT6s. Subjective and objective sleep quality was registered with sleep diaries and actigraphy on a daily basis. Cognitive performance, as measured by vigilance and reaction time, was measured with the Vienna test system on days 1 and 7. Light exposure was measured in the vessel compartments daily.Results The rhythm of aMT6s shifted significantly from 4.78 +/- 0.94 h on day 1 to 8.84 +/- 1.76 h on day 7. Rate of adaptation was 0.84 h per day. Subjective sleep quality showed significant time effects on four variables, but objective sleep quality did not show any significant time effects. Vigilance and reaction time improved significantly from days 1 to 7. Light exposure intensities varied between 3 and 243 lux.Conclusions This field study showed that offshore fleet workers are able to adapt to the imposed regimen of 12-h night shifts. The adaptation is slower compared to other branches of the offshore industry, which most likely is due to lower light exposure. Subjective sleep quality improved to some extent, but the results were not conclusive. No significant effects were observed in the objective measures. Cognitive performance improved significantly, which was likely to be caused by the extended working hours on day 1 and an entrainment of the suprachiasmatic nuclei (SCN).
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Previous studies in simulated and real-world shift work show that rhythms of circadian markers are resistant to phase shifting, indicating the endogenous SCN rhythm is slow to adapt to shift work schedules.
“Previous studies in both simulated (10, 11) and real-world (12, 13) shift work have shown that the rhythms of these circadian markers are resistant to phase shifting, indicating that the endogenous SCN rhythm is slow to adapt to shift work schedules.”
From Separation of circadian- and behavior-driven metabolite rhythms in humans provides a window on peripheral oscillators and metabolism (2018) · cites this paper as [12]
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- Authors
- Hansen, J. H., Geving, I. H., & Reinertsen, R. E.
- Affiliations
- SINTEF (NO)
- Corresponding author
- Hansen, Jakob H.
- ORCID
- Reinertsen, Randi E.
- Venue
- International Archives of Occupational and Environmental Health
- Published
- 2010-05-25
- Volume
- 83
- Issue
- 6
- Pages
- 607-615
- ISSN
- 0340-0131 (ISSN-L)
- 1432-1246
- OpenAlex
- W2093021663
- Cited by
- 29
- References
- 60
- Citations by year
- 2026: 1 · 2025: 1 · 2024: 2 · 2023: 3 · 2022: 2 · 2021: 3 · 2020: 2 · 2019: 2 · 2018: 5 · 2016: 2 · 2015: 2 · 2013: 1 · 2012: 1
- FWCI
- 1.67
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- www.springer.com/tdm (tdm)
- Locations
- International Archives of Occupational and Environmental Health (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Norges Forskningsråd
- Topics
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Sleep and Work-Related Fatigue
- Life Sciences › Neuroscience › Endocrine and Autonomic Systems › Circadian rhythm and melatonin
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Sleep and related disorders
- Keywords
- 6-sulfatoxymelatonin, circadian rhythm, shift work, night shift work, offshore workers, speed of adjustment, sleep quality, cognitive performance, sustained attention, reaction time, light exposure, suprachiasmatic nucleus, melatonin
- MeSH terms
- Adult, Circadian Rhythm, Female, Humans, Male, Melatonin, Middle Aged, Psychomotor Performance, Surveys and Questionnaires, Sleep, Wakefulness, Work Schedule Tolerance, Young Adult, Actigraphy
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