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Cited by 206Advanced Glycation End Products researchPotato Plant ResearchFood Nutrient Composition and Product Development

The DOI matches its Crossref record; 50 of the 50 references it cites were found in a registry or an index.

Determination of N ɛ-(carboxymethyl)lysine in food systems by ultra performance liquid chromatography-mass spectrometry

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Assar, Shima H., Moloney, Catherine, Lima, Maria, Magee, Ronald, Ames, Jennifer M.·2009·Amino Acids
DOI 10.1007/s00726-008-0071-4
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Abstract

We report the use of ultra pressure liquid chromatography (UPLC), coupled to a tandem mass spectrometer operated in multiple reaction monitoring mode to determine the advanced glycation endproduct, Nepsilon-(carboxymethyl)lysine (CML). The procedure was applied to acid hydrolyzates of protein isolated from a range of foods (milks processed at different temperatures, butter, cheese, infant formulae, bread, raw and cooked minced beef and olive oil). Highest levels of CML were determined in white bread crust (15.2 +/- 0.63 mmol/mol Lys), wholemeal bread crust (13.1 +/- 0.61 mmol/mol Lys) and evaporated full-fat milk (4.86 +/- 0.77 mmol/mol Lys). Lowest levels of CML were measured in raw minced beef beef (0.03 +/- 002 mmol/mol Lys), raw full-fat cow's milk (0.08 +/- 0.03 mmol/mol Lys) and pasteurized skimmed cow's milk (0.09 +/- 0.002 mmol/mol Lys). CML could not be detected in olive oil.

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  1. Food Standards Agency (2002) McCance and Widdowson’s the composition of foods, 6th summary edn. Royal Society of Chemistry, Cambridge

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Metadata

Authors
Assar, S. H., Moloney, C., Lima, M., Magee, R., & Ames, J. M.
Affiliations
Queen's University Belfast (GB)
Corresponding author
Ames, Jennifer M.
ORCID
Venue
Amino Acids
Publisher
Springer Science and Business Media LLC
Published
2008-04-04
Volume
36
Issue
2
Pages
317-326
ISSN
  • 0939-4451 (ISSN-L)
  • 1438-2199
DOI
10.1007/s00726-008-0071-4
OpenAlex
W1999234525
Cited by
206
References
50
Citations by year
2026: 3 · 2025: 9 · 2024: 9 · 2023: 14 · 2022: 9 · 2021: 21 · 2020: 14 · 2019: 10 · 2018: 9 · 2017: 13 · 2016: 12 · 2015: 20 · 2014: 14 · 2013: 17 · 2012: 3
FWCI
6.42
Type
journal article
Language
en
Open access
Licence
Locations
  • Amino Acids (publishedVersion)
  • PubMed (publishedVersion)
  • UWE Research Repository (UWE Bristol) (submittedVersion, cc-by)
Funders
Food Standards Agency
Topics
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Clinical Biochemistry › Advanced Glycation End Products research
  • Life Sciences › Agricultural and Biological Sciences › Food Science › Potato Plant Research
  • Life Sciences › Agricultural and Biological Sciences › Food Science › Food Nutrient Composition and Product Development
Keywords
carboxymethyllysine, advanced glycation end products, food proteins, milk, bread, cheese, infant formula, beef, olive oil, thermal processing, UPLC-MS/MS
MeSH terms
Animals, Bread, Chromatography, High Pressure Liquid, Food Analysis, Lysine, Meat, Milk, Tandem Mass Spectrometry

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