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Loop-mediated isothermal amplification (LAMP): a rapid, accurate, and cost-effective diagnostic method for infectious diseases
Open accessAbstract
Loop-mediated isothermal amplification (LAMP) is an established nucleic acid amplification method offering rapid, accurate, and cost-effective diagnosis of infectious diseases. This technology has been developed into commercially available detection kits for a variety of pathogens including bacteria and viruses. The current focus on LAMP methodology is as a diagnostic system to be employed in resource-limited laboratories in developing countries, where many fatal tropical diseases are endemic. The combination of LAMP and novel microfluidic technologies such as Lab-on-a-chip may facilitate the realization of genetic point-of-care testing systems to be used by both developed and developing countries in the near future. This review will describe the historical, current, and future developments of such technologies.
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Citations
Cites
The origins and the future of microfluidics
Whitesides, G. M. (2006) · Nature · doi:10.1038/nature05058 · Cited by 9,687
The Pathology of Influenza Virus Infections
Taubenberger, J. K., & Morens, D. M. (2008) · Annual Review of Pathology: Mechanisms of Disease · doi:10.1146/annurev.pathmechdis.3.121806.154316 · Cited by 1,111
Cited by
Diagnosis and epidemiology of leptospirosis
Picardeau, M. (2013) · Médecine et Maladies Infectieuses · doi:10.1016/j.medmal.2012.11.005 · Cited by 398
Circulating miRNAs: Roles in cancer diagnosis, prognosis and therapy
Cheng, G. (2015) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2014.09.001 · Cited by 334
Loop-mediated isothermal amplification methods for diagnosis of bacterial meningitis
Seki, M., Kilgore, P. E., Kim, E. J., Ohnishi, M., Hayakawa, S., & Kim, D. W. (2018) · Frontiers in Pediatrics · doi:10.3389/fped.2018.00057 · Cited by 60
Kim, D. W., Kilgore, P. E., Kim, E. J., Kim, S. A., Anh, D. D., & Seki, M. (2011) · Journal of Clinical Microbiology · doi:10.1128/jcm.00515-11 · Cited by 50
Kim, D. W., Kilgore, P. E., Kim, E. J., Kim, S. A., Anh, D. D., Dong, B. Q., Kim, J. S., & Seki, M. (2012) · PLoS ONE · doi:10.1371/journal.pone.0042954 · Cited by 50
Metadata
- Authors
- Mori, Y., & Notomi, T.
- Venue
- Journal of Infection and Chemotherapy
- Publisher
- Elsevier BV
- Published
- 2009
- Volume
- 15
- Issue
- 2
- Pages
- 62-69
- ISSN
- 1341-321X (ISSN-L)
- OpenAlex
- W2057876450
- Cited by
- 1,015
- References
- 2
- FWCI
- 21.16
- Type
- journal article
- Language
- en
- Open access
- green
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- Mori, Y., & Notomi, T. (2009). Loop-mediated isothermal amplification (LAMP): a rapid, accurate, and cost-effective diagnostic method for infectious diseases. Journal of Infection and Chemotherapy. https://doi.org/10.1007/s10156-009-0669-9
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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