Can ECAP measures be used for totally objective programming of cochlear implants?
Open accessAbstract
An experiment was conducted with eight cochlear implant subjects to investigate the feasibility of using electrically evoked compound action potential (ECAP) measures other than ECAP thresholds to predict the way that behavioral thresholds change with rate of stimulation, and hence, whether they can be used without combination with behavioral measures to determine program stimulus levels for cochlear implants. Loudness models indicate that two peripheral neural response characteristics contribute to the slope of the threshold versus rate function: the way that neural activity to each stimulus pulse decreases as rate increases and the slope of the neural response versus stimulus current function. ECAP measures related to these two characteristics were measured: the way that ECAP amplitude decreases with stimulus rate and the ECAP amplitude growth function, respectively. A loudness model (incorporating temporal integration and the two neural response characteristics) and regression analyses were used to evaluate whether the ECAP measures could predict the average slope of the behavioral threshold versus current function and whether individual variation in the measures could predict individual variation in the slope of the threshold function. The average change of behavioral threshold with increasing rate was well predicted by the model when using the average ECAP data. However, the individual variations in the slope of the thresholds versus rate functions were not well predicted by individual variations in ECAP data. It was concluded that these ECAP measures are not useful for fully objective programming, possibly because they do not accurately reflect the neural response characteristics assumed by the model, or are measured at current levels much higher than threshold currents.
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Other measures like ECAP, EABR, and CAEPs have been studied to automatically fit cochlear implants, but none of them reached a clinical application.
“Other measures like ECAP (McKay et al., 2013), electrically evocated auditory brainstem response (EABR) (Guenser et al., 2015), cortical auditory evoked potentials (CAEPs) (Visram et al., 2015) have been studied to automatically fit cochlear implants, but none of them reached a clinical application.”
From Toward a personalized closed-loop stimulation of the visual cortex: Advances and challenges (2022) · cites this paper as McKay et al., 2013
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Self-citationToward a personalized closed-loop stimulation of the visual cortex: Advances and challenges
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- Authors
- McKay, C. M., Chandan, K., Akhoun, I., Siciliano, C., & Kluk, K.
- Affiliations
- Bionics Institute (AU)
- University of Manchester (GB)
- Corresponding author
- McKay, Colette M.
- Venue
- Journal of the Association for Research in Otolaryngology
- Published
- 2013-09-19
- Volume
- 14
- Issue
- 6
- Pages
- 879-890
- ISSN
- 1438-7573 (ISSN-L)
- 1525-3961
- PMC
- PMC3825020
- OpenAlex
- W1991315097
- Cited by
- 81
- References
- 28
- Citations by year
- 2026: 5 · 2025: 10 · 2024: 6 · 2023: 5 · 2022: 8 · 2021: 7 · 2020: 3 · 2019: 4 · 2018: 4 · 2017: 11 · 2016: 9 · 2015: 5 · 2014: 4
- FWCI
- 3.29
- Type
- journal article
- Language
- en
- Open access
- hybrid
- doi.org
- Locations
- Journal of the Association for Research in Otolaryngology (publishedVersion, cc-by)
- Europe PMC (PubMed Central) (publishedVersion, cc-by-nc)
- PubMed Central (publishedVersion, cc-by-nc)
- PubMed (publishedVersion)
- Research Explorer (The University of Manchester) (publishedVersion)
- Minerva Access (University of Melbourne) (submittedVersion, cc-by-nc)
- Funders
- State Government of Victoria
- Medical Research Council
- Topics
- Life Sciences › Neuroscience › Cognitive Neuroscience › Hearing Loss and Rehabilitation
- Life Sciences › Neuroscience › Sensory Systems › Hearing, Cochlea, Tinnitus, Genetics
- Social Sciences › Psychology › Developmental and Educational Psychology › Hearing Impairment and Communication
- Keywords
- cochlear implants, electrically evoked compound action potential, loudness model, temporal integration, behavioral thresholds, interindividual variability
- MeSH terms
- Action Potentials, Auditory Threshold, Cochlea, Cochlear Implants, Evoked Potentials, Auditory, Humans
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