Cited by 32Cardiovascular Syncope and Autonomic DisordersSpaceflight effects on biologyHeart Rate Variability and Autonomic Control

Orthostatic heart rate responses after prolonged space flights

Tank, Jens, Baevsky, Roman M., Funtova, Irina I., Diedrich, André, Slepchenkova, Irina N., Jordan, Jens·2011·Clinical Autonomic Research

Abstract

Orthostatic tachycardia (POTS) can occur after space flights. We determined orthostatic heart rate responses in 18 cosmonauts before and 3-5 days after long-term space missions. Cosmonauts undergoing a cardiovascular training program in space experienced only moderate POTS after their return to earth. Cardiovascular countermeasures may have attenuated POTS. Another possible interpretation is that cardiovascular deconditioning is not sufficient to elicit full blown POTS in the absence of additional genetic or environmental factors.

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Registry

Crossref · 10.1007/s10286-010-0106-2

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14 of 14 references verified0 citation errors · 0 not checkable

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  • In 18 cosmonauts who had spent several months on a space station, previously healthy individuals experienced moderate hemodynamic changes that almost meet some POTS criteria (average orthostatic heart rate increase by 26 bpm in absence of orthostatic hypotension), with one individual meeting the orthostatic tachycardia criterion (heart rate increase by 31 bpm), despite regular cardiovascular exer

    “Another study in 18 cosmonauts, who had spent several months on a space station, demonstrated that previously healthy individuals can experience moderate hemodynamic changes that almost meet some POTS criteria (average orthostatic heart rate increase by 26 bpm in the absence of orthostatic hypotension), with one individual meeting the orthostatic tachycardia criterion (heart rate increase by 31 b”
  • In POTS, the physiological reactions to orthostatic stress are similar to those seen in deconditioning from prolonged bed rest or space flight, including tachycardia, exercise intolerance, and lower left ventricular mass, stroke volume, and blood volume.

    “The physiological responses to orthostatic stress in POTS often resemble the clinical phenotype of patients with deconditioning from prolonged bed rest or space flight (e.g.tachycardia, exercise intolerance, and reductions in left ventricular mass, stroke volume, blood volume) (Fu et al., 2010a;Levine et al., 1997;Tank et al., 2011).”

    From Postural tachycardia syndrome – Diagnosis, physiology, and prognosis (2018) · cites this paper as Tank et al., 2011

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Authors
Tank, J., Baevsky, R. M., Funtova, I. I., Diedrich, A., Slepchenkova, I. N., & Jordan, J.
Affiliations
  • Medizinische Hochschule Hannover (DE)
  • Institute of Biomedical Problems (RU)
  • Vanderbilt University (US)
Corresponding author
Tank, Jens
Venue
Clinical Autonomic Research
Published
2010-12-25
Volume
21
Issue
2
Pages
121-124
ISSN
  • 0959-9851 (ISSN-L)
  • 1619-1560
OpenAlex
W1975129549
Cited by
32
References
14
Citations by year
2026: 1 · 2025: 2 · 2024: 2 · 2023: 1 · 2022: 4 · 2021: 1 · 2020: 4 · 2019: 4 · 2018: 2 · 2016: 3 · 2015: 2 · 2014: 2 · 2013: 3 · 2012: 1
FWCI
1.35
Type
journal article
Language
en
Open access
closed
Locations
  • Clinical Autonomic Research (publishedVersion)
  • PubMed (publishedVersion)
Funders
  • Deutsches Zentrum für Luft- und Raumfahrt
  • National Heart, Lung, and Blood Institute (P01HL056693)
Topics
  • Health Sciences › Medicine › Surgery › Cardiovascular Syncope and Autonomic Disorders
  • Health Sciences › Medicine › Physiology › Spaceflight effects on biology
  • Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Heart Rate Variability and Autonomic Control
Keywords
orthostatic tachycardia, postural orthostatic tachycardia syndrome, cosmonauts, cardiovascular deconditioning, autonomic dysfunction
MeSH terms
Adult, Heart Rate, Humans, Male, Space Flight, Weightlessness, Exercise, Cardiovascular Deconditioning, Postural Orthostatic Tachycardia Syndrome

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