Cited by 97HIV/AIDS Research and InterventionsHIV, Drug Use, Sexual RiskSubstance Abuse Treatment and Outcomes

Level of Alcohol Use Associated with HIV Care Continuum Targets in a National U.S. Sample of Persons Living with HIV Receiving Healthcare

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Williams, Emily C., McGinnis, Kathleen A., Edelman, E. Jennifer, Matson, Theresa E., Gordon, Adam J., Marshall, Brandon D. L., Bryant, Kendall J., Rubinsky, Anna D. +7 more·2019·AIDS and Behavior

Abstract

We evaluated associations between levels of alcohol use and HIV care continuum components using national Veterans Aging Cohort Study data for all patients with HIV and AUDIT-C screening (2/1/2008-9/30/2014). Poisson regression models evaluated associations between alcohol use levels (non-drinking, low-, medium-, high-, and very high-level drinking) and: (1) engagement with care (documented CD4 cells/µl or viral load copies/ml labs), (2) ART treatment (≥ 1 prescription), and (3) viral suppression (HIV RNA < 500 copies/ml) within one year. Among 33,224 patients, alcohol use level was inversely associated with all care continuum outcomes (all p < 0.001). Adjusted prevalence of care engagement ranged from 77.8% (95% CI 77.1-78.4%) for non-drinking to 69.1% (66.6-71.6%) for high-level drinking. The corresponding range for ART treatment was 74.0% (73.3-74.7%) to 60.1% (57.3-62.9%) and for viral suppression was 57.3% (56.5-58.1%) to 38.3% (35.6-41.1%). Greater alcohol use is associated with suboptimal HIV treatment across the HIV care continuum.

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  • Unhealthy alcohol use among people with HIV is associated with significant health-related consequences, including mortality, lack of viral suppression, less ART utilization, and sub-optimal adherence to ART.

    “Unhealthy alcohol use is prevalent among people with HIV (PWH) and associated with significant health-related consequences.”

    From A Randomized Feasibility/Acceptability Trial of Acceptance and Commitment Therapy for People with HIV Who Drink at Unhealthy Levels. (2026) · cites this paper as [8]

    The Discussion (page unavailable) reports that higher alcohol use was associated with lower ART treatment and viral suppression, and describes an association with ART adherence. The paper does not report a mortality finding, so it supports the citing sentence’s general point about health-related consequences but not every consequence listed in the supplied paraphrase. (LLM, conf=0.84)

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  1. [56]Williams EC, Lapham GT, Shortreed SM, Among patients with unhealthy alcohol use, those with HIV are less likely than those without to receive evidence-based alcohol-related care: A national VA study. Drug Alcohol Depend. 5 01 2017; 174: 113– 120. 28324813 PMC5444382

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Authors
Williams, E. C., McGinnis, K. A., Edelman, E. J., Matson, T. E., Gordon, A. J., Marshall, B. D. L., Bryant, K. J., Rubinsky, A. D., Lapham, G. T., Satre, D. D., Richards, J. E., Catz, S. L., Fiellin, D. A., Justice, A. C., & Bradley, K. A.
Affiliations
  • University of Washington (US)
  • VA Connecticut Healthcare System (US)
  • Yale University (US)
  • Kaiser Permanente Washington Health Research Institute (US)
  • University of Pittsburgh (US)
  • Brown University (US)
  • National Institute on Alcohol Abuse and Alcoholism (US)
  • University of California, San Francisco (US)
  • Kaiser Permanente (US)
  • University of California, Davis (US)
Corresponding author
Williams, Emily C.
Venue
AIDS and Behavior
Published
2018-07-09
Volume
23
Issue
1
Pages
140-151
ISSN
  • 1090-7165 (ISSN-L)
  • 1573-3254
OpenAlex
W2836518291
Cited by
97
References
64
Citations by year
2026: 5 · 2025: 10 · 2024: 15 · 2023: 15 · 2022: 13 · 2021: 16 · 2020: 14 · 2019: 8 · 2018: 1
FWCI
7.38
Type
journal article
Language
en
Open access
Locations
  • AIDS and Behavior (publishedVersion)
  • PubMed (publishedVersion)
  • Europe PMC (PubMed Central) (acceptedVersion)
  • PubMed Central (acceptedVersion)
  • eScholarship (California Digital Library) (submittedVersion)
Funders
  • National Institute on Alcohol Abuse and Alcoholism (R21AA022866-01, K24-AA022128)
  • COMpAAAS/Veterans Aging Cohort Study (U24-AA020794, U01-AA020790, U01-AA020795, U01-AA020799, U10 AA013566)
  • VA Health Services Research & Development (CDA 12-276)
Topics
  • Health Sciences › Medicine › Infectious Diseases › HIV/AIDS Research and Interventions
  • Health Sciences › Medicine › Epidemiology › HIV, Drug Use, Sexual Risk
  • Health Sciences › Medicine › Epidemiology › Substance Abuse Treatment and Outcomes
Keywords
alcohol consumption, HIV care continuum, HIV care engagement, antiretroviral therapy, viral suppression, CD4 count, veterans
MeSH terms
Assessment of Medication Adherence, Alcohol Drinking, Continuity of Patient Care, Female, Humans, Male, Middle Aged, Retrospective Studies, United States, Veterans, Health Behavior, HIV Infections, Drug Monitoring, Anti-HIV Agents, Viral Load, Medication Adherence

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