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Nonparametric Estimation from Incomplete Observations

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Nonparametric Estimation from Incomplete Observations

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A Multigene Assay to Predict Recurrence of Tamoxifen-Treated, Node-Negative Breast Cancer

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Gene-expression profiles to predict distant metastasis of lymph-node-negative primary breast cancer

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Gene Expression and Benefit of Chemotherapy in Women With Node-Negative, Estrogen Receptor–Positive Breast Cancer

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American Society of Clinical Oncology 2007 Update of Recommendations for the Use of Tumor Markers in Breast Cancer

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The MicroArray Quality Control (MAQC) project shows inter- and intraplatform reproducibility of gene expression measurements

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Gene Expression Profiling in Breast Cancer: Understanding the Molecular Basis of Histologic Grade To Improve Prognosis

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Genes that mediate breast cancer metastasis to the brain

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MicroRNA-139 suppresses proliferation in luminal type breast cancer cells by targeting Topoisomerase II alpha

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A functional in vivo screen for regulators of tumor progression identifies HOXB2 as a regulator of tumor growth in breast cancer

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TRADD contributes to tumour suppression by regulating ULF-dependent p19Arf ubiquitylation

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Functional screening implicates miR-371-3p and peroxiredoxin 6 in reversible tolerance to cancer drugs

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GPER mediates decreased chemosensitivity via regulation of ABCG2 expression and localization in tamoxifen-resistant breast cancer cells

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Bioinformatic Identification of miR-622 Key Target Genes and Experimental Validation of the miR-622-RNF8 Axis in Breast Cancer

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The disbalance of LRP1 and SIRPα by psychological stress dampens the clearance of tumor cells by macrophages

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Elevated nuclear S100P expression is associated with poor survival in early breast cancer patients.

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Global analysis of ZNF217 chromatin occupancy in the breast cancer cell genome reveals an association with ERalpha

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MEL-18 loss mediates estrogen receptor–α downregulation and hormone independence

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Small molecule inhibitor of the bone morphogenetic protein pathway DMH1 reduces ovarian cancer cell growth

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Proteomic identification of prognostic tumour biomarkers, using chemotherapy-induced cancer-associated fibroblasts

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Downregulation of histone H2A and H2B pathways is associated with anthracycline sensitivity in breast cancer

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Phospholipase Cδ1 suppresses cell migration and invasion of breast cancer cells by modulating KIF3A-mediated ERK1/2/β- catenin/MMP7 signalling

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Pathologic evaluation of tumor-associated macrophage density and vessel inflammation in invasive breast carcinomas

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HDAC2 and HDAC5 Up-Regulations Modulate Survivin and miR-125a-5p Expressions and Promote Hormone Therapy Resistance in Estrogen Receptor Positive Breast Cancer Cells

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Novel Prognostic Markers in Triple-Negative Breast Cancer Discovered by MALDI-Mass Spectrometry Imaging

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Quantifying Argonaute 2 (Ago2) expression to stratify breast cancer

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PRMT1 Is Critical for the Transcriptional Activity and the Stability of the Progesterone Receptor

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Predicting the most deleterious missense nsSNPs of the protein isoforms of the human HLA-G gene and in silico evaluation of their structural and functional consequences

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Coagulation factor V is a marker of tumor-infiltrating immune cells in breast cancer

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The tissue expression of MCT3, MCT8, and MCT9 genes in women with breast cancer

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USP22 promotes HER2-driven mammary carcinoma aggressiveness by suppressing the unfolded protein response

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CDT1 Is a Novel Prognostic and Predictive Biomarkers for Hepatocellular Carcinoma

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ZHX2 promotes HIF1α oncogenic signaling in triple-negative breast cancer

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Ubiquitin-conjugating enzyme 2C (UBE2C) is a poor prognostic biomarker in invasive breast cancer

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Identification and analysis of dysregulated fatty acid metabolism genes in breast cancer subtypes

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ESRP1-regulated isoform switching of LRRFIP2 determines metastasis of gastric cancer

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A Combined Shotgun and Targeted Mass Spectrometry Strategy for Breast Cancer Biomarker Discovery

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Low expression levels of hepsin and TMPRSS3 are associated with poor breast cancer survival

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Dichotomous roles for the orphan nuclear receptor NURR1 in breast cancer

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Bisected, complex N-glycans and galectins in mouse mammary tumor progression and human breast cancer

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Identification of vitamin D3 target genes in human breast cancer tissue

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Chemerin enhances mesenchymal features of glioblastoma by establishing autocrine and paracrine networks in a CMKLR1-dependent manner

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Expression patterns and therapeutic implications of CDK4 across multiple carcinomas: a molecular docking and MD simulation study

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Transcription factor c-Jun modulates GLUT1 in glycolysis and breast cancer metastasis

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Nicotinamide N‐methyltransferase sustains a core epigenetic program that promotes metastatic colonization in breast cancer

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Myosin 1e promotes breast cancer malignancy by enhancing tumor cell proliferation and stimulating tumor cell de-differentiation

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Phosphatidylinositol glycan anchor biosynthesis, class X containing complex promotes cancer cell proliferation through suppression of EHD2 and ZIC1, putative tumor suppressors

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The prognostic values of signal transducers activators of transcription family in ovarian cancer

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Clinicopathological and prognostic significance of SDC1 overexpression in breast cancer

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Prognostic roles of signal transducers and activators of transcription family in human breast cancer

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miR-376a inhibits breast cancer cell progression by targeting neuropilin-1 NR

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Kinesin family member-18A (KIF18A) is a predictive biomarker of poor benefit from endocrine therapy in early ER+ breast cancer

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LATS1 and LATS2 suppress breast cancer progression by maintaining cell identity and metabolic state

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Expression patterns and the prognostic value of the SMYD family members in human breast carcinoma using integrative bioinformatics analysis

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FOXA1 is Prognostic of Triple Negative Breast Cancers by Transcriptionally Suppressing SOD2 and IL6

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DAXX Suppresses Tumor-Initiating Cells in Estrogen Receptor–Positive Breast Cancer Following Endocrine Therapy

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Prognostic roles of MAGE family�members in breast cancer based on KM‑Plotter Data

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The Prognosis Of Peroxiredoxin Family In Breast Cancer

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FGF13 promotes metastasis of triple‐negative breast cancer

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UDP-glucose 6-dehydrogenase knockout impairs migration and decreases in vivo metastatic ability of breast cancer cells

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HDAC8 suppresses the epithelial phenotype and promotes EMT in chemotherapy-treated basal-like breast cancer

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Paradoxical Roles of Mineral Dust Induced Gene on Cell Proliferation and Migration/Invasion

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A Positive Feedback Loop Between TGFβ and Androgen Receptor Supports Triple-negative Breast Cancer Anoikis Resistance

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Integrated single-cell analysis reveals distinct epigenetic-regulated cancer cell states and a heterogeneity-guided core signature in tamoxifen-resistant breast cancer

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Maspin is not required for embryonic development or tumour suppression

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Increased expression of mdig predicts poorer survival of the breast cancer patients

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Naringin suppresses the development of glioblastoma by inhibiting FAK activity

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The dual role of asporin in breast cancer progression

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Synthetic lethality between HER2 and transaldolase in intrinsically resistant HER2-positive breast cancers

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Bioinformatics analysis of the prognostic value of CCT6A and associated signalling pathways in breast cancer

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MicroRNA-150-5p promotes cell motility by inhibiting c-Myb-mediated Slug suppression and is a prognostic biomarker for recurrent ovarian cancer

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mTOR/HDAC1 Crosstalk Mediated Suppression of ADH1A and ALDH2 Links Alcohol Metabolism to Hepatocellular Carcinoma Onset and Progression in silico

Zahid, K. R., Yao, S., Khan, A. R. R., Raza, U., & Gou, D. (2019) · Frontiers in Oncology · doi:10.3389/fonc.2019.01000 · Cited by 36

Epigenetic Identification of ADCY4 as a Biomarker for Breast Cancer: an Integrated Analysis of Adenylate Cyclases

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Significant association between high serum CCL5 levels and better disease‐free survival of patients with early breast cancer

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SETD3 acts as a prognostic marker in breast cancer patients and modulates the viability and invasion of breast cancer cells

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Adenocarcinoma of the Uterine Cervix Shows Impaired Recruitment of cDC1 and CD8+ T Cells and Elevated β-Catenin Activation Compared with Squamous Cell Carcinoma

Rotman, J., Heeren, A. M., Gassama, A. A., Lougheed, S. M., Pocorni, N., Stam, A. G. M., Bleeker, M. C. G., Zijlmans, H. J. M. A. A., Mom, C. H., Kenter, G. G., et al. (2020) · Clinical Cancer Research · doi:10.1158/1078-0432.ccr-19-3826 · Cited by 35

HOTAIR promotes paclitaxel resistance by regulating CHEK1 in ovarian cancer

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Activation of the Ion Channel TRPV4 Induces Epithelial to Mesenchymal Transition in Breast Cancer Cells

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Tumor-associated antigen Prame targets tumor suppressor p14/ARF for degradation as the receptor protein of CRL2Prame complex

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CST in maintaining genome stability: Beyond telomeres

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Expression status and prognostic value of the perilipin family of genes in breast cancer.

Zhang, X., Su, L., & Sun, K. (2021) · PubMed Central · Cited by 33

HMGA2 Supports Cancer Hallmarks in Triple-Negative Breast Cancer

Mansoori, B., Terp, M. G., Mohammadi, A., Pedersen, C. B., Ditzel, H. J., Baradaran, B., & Gjerstorff, M. F. (2021) · Cancers · doi:10.3390/cancers13205197 · Cited by 34

Cryptolepine Targets TOP2A and Inhibits Tumor Cell Proliferation in Breast Cancer Cells -An In vitroandIn silicoStudy

Mehraj, U., Qayoom, H., Shafi, S., Farhana, P. S., Asdaq, S. M. B., & Mir, M. A. (2022) · Anti-Cancer Agents in Medicinal Chemistry · doi:10.2174/1871520622666220419135547 · Cited by 34

HSPA8 Is a New Biomarker of Triple Negative Breast Cancer Related to Prognosis and Immune Infiltration

Ying, B., Xu, W., Nie, Y. G., & Li, Y. (2022) · Disease Markers · doi:10.1155/2022/8446857 · Cited by 34

Studies of postpartum mammary gland involution reveal novel pro-metastatic mechanisms

Wallace, T. R., Tarullo, S. E., Crump, L. S., & Lyons, T. R. (2019) · Journal of Cancer Metastasis and Treatment · doi:10.20517/2394-4722.2019.01 · Cited by 31

Interactive online consensus survival tool for esophageal squamous cell carcinoma prognosis analysis

Wang, Q., Wang, F., Lv, J., Xin, J., Xie, L., Zhu, W., Tang, Y., Li, Y., Zhao, X., Wang, Y., et al. (2019) · Oncology Letters · doi:10.3892/ol.2019.10440 · Cited by 33

cSurvival: a web resource for biomarker interactions in cancer outcomes and in cell lines

Cheng, X., Liu, Y., Wang, J., Chen, Y., Robertson, A. G., Zhang, X., Jones, S. J. M., & Taubert, S. (2022) · Briefings in Bioinformatics · doi:10.1093/bib/bbac090 · Cited by 36

Germline polymorphisms in an enhancer of PSIP1 are associated with progression-free survival in epithelial ovarian cancer

French, J. D., Australian Ovarian Cancer Study Group, Study, A. C., Johnatty, S. E., Lu, Y., Beesley, J., Gao, B., Kalimutho, M., Henderson, M. J., Russell, A. J., et al. (2016) · Oncotarget · doi:10.18632/oncotarget.7047 · Cited by 31

Blockade of extracellular NM23 or its endothelial target slows breast cancer growth and metastasis

Yokdang, N., Nordmeier, S., Speirs, K., Burkin, H. R., & Buxton, I. L. O. (2015) · Integrative Cancer Science and Therapeutics · doi:10.15761/icst.1000139 · Cited by 33

The prognostic roles of ALDH1 isoenzymes in gastric cancer

Wang, Z., Li, K., Guo, X., Li, X., Bu, Y., Bai, X., Zheng, L., & Huang, Y. (2016) · OncoTargets and Therapy · doi:10.2147/ott.s102314 · Cited by 33

Proteasome ubiquitin receptor PSMD4 is an amplification target in breast cancer and may predict sensitivity to PARPi

Fejzo, M. S., Anderson, L. A., Chen, H., Guandique, E., Kalous, O., Conklin, D. F., & Slamon, D. J. (2017) · Genes Chromosomes and Cancer · doi:10.1002/gcc.22459 · Cited by 33

BASP1 interacts with oestrogen receptor α and modifies the tamoxifen response

Marsh, L. A., Carrera, S., Shandilya, J., Heesom, K. J., Davidson, A. D., Medler, K. F., & Roberts, S. G. E. (2017) · Cell Death and Disease · doi:10.1038/cddis.2017.179 · Cited by 32

RNA binding protein RALY promotes Protein Arginine Methyltransferase 1 alternatively spliced isoform v2 relative expression and metastatic potential in breast cancer cells

Bondy‐Chorney, E., Baldwin, R. M., Didillon, A., Chabot, B., Jasmin, B. J., & Côté, J. (2017) · The International Journal of Biochemistry & Cell Biology · doi:10.1016/j.biocel.2017.07.008 · Cited by 33

Identification of Breast Cancer Stem Cell Related Genes Using Functional Cellular Assays Combined With Single-Cell RNA Sequencing in MDA-MB-231 Cells

Jonasson, E., Ghannoum, S., Persson, E., Karlsson, J. W., Kroneis, T., Larsson, E., Landberg, G., & Ståhlberg, A. (2019) · Frontiers in Genetics · doi:10.3389/fgene.2019.00500 · Cited by 33

Unraveling FATP1, regulated by ER-β, as a targeted breast cancer innovative therapy

Mendes, C., Lopes‐Coelho, F., Ramos, C., Martins, F., Santos, I. P., Rodrigues, A., SILVA, F. A. B. N. D., André, S., & Serpa, J. (2019) · Scientific Reports · doi:10.1038/s41598-019-50531-3 · Cited by 35

CDK7 Inhibition Is Effective in all the Subtypes of Breast Cancer: Determinants of Response and Synergy with EGFR Inhibition

McDermott, M. S. J., Sharko, A. C., Munie, J., Kassler, S., Melendez, T., Lim, C., & Broude, E. V. (2020) · Cells · doi:10.3390/cells9030638 · Cited by 33

Mechanoactivation of NOX2-generated ROS elicits persistent TRPM8 Ca 2+ signals that are inhibited by oncogenic KRas

Pratt, S. J. P., Lee, R., Chang, K. T., Hernández‐Ochoa, E. O., Annis, D. A., Ory, E. C., Thompson, K. N., Bailey, P. C., Mathias, T. J., Ju, J. A., et al. (2020) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2009495117 · Cited by 33

The epithelial sodium channel has a role in breast cancer cell proliferation

Ware, A., Harris, J. J., Slatter, T. L., Cunliffe, H. E., & McDonald, F. J. (2021) · Breast Cancer Research and Treatment · doi:10.1007/s10549-021-06133-7 · Cited by 33

Short term starvation potentiates the efficacy of chemotherapy in triple negative breast cancer via metabolic reprogramming

Pateras, I. S., Williams, C., Gianniou, D. D., Margetis, A. T., Avgeris, M., Rousakis, P., Legaki, A., Mirtschink, P., Zhang, W., Panoutsopoulou, K., et al. (2023) · Journal of Translational Medicine · doi:10.1186/s12967-023-03935-9 · Cited by 33

Hierarchical Clustering of Breast Cancer Methylomes Revealed Differentially Methylated and Expressed Breast Cancer Genes

Lin, I., Chen, D.-T., Chang, Y.-F., Lee, Y.-L., Su, C.-H., Cheng, C., Tsai, Y.-C., Ng, S.-C., Chen, H.-T., Lee, M., et al. (2015) · PLoS ONE · doi:10.1371/journal.pone.0118453 · Cited by 33

OCT1 Is a Poor Prognostic Factor for Breast Cancer Patients and Promotes Cell Proliferation via Inducing NCAPH

Ogura, T., Azuma, K., Sato, J., Kinowaki, K., Takayama, K., Takeiwa, T., Kawabata, H., & Inoue, S. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms222111505 · Cited by 32

Antitumoral Activity of a CDK9 PROTAC Compound in HER2-Positive Breast Cancer

Noblejas‐López, M. D. M., Gandullo‐Sánchez, L., Galán‐Moya, E. M., López‐Rosa, R., Tébar-García, D., Nieto‐Jiménez, C., Sango, M. G., Burgos, M., Pandiella, A., & Ocaña, A. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23105476 · Cited by 35

Loss of Dickkopf 3 Promotes the Tumorigenesis of Basal Breast Cancer

Lorsy, E., Topuz, A. S., Geisler, C., Stahl, S., Garczyk, S., von Stillfried, S. F., Hoß, M., Gluz, O., Hartmann, A., Knüchel, R., et al. (2016) · PLoS ONE · doi:10.1371/journal.pone.0160077 · Cited by 32

Interleukin enhancer-binding factor 3 and HOXC8 co-activate cadherin 11 transcription to promote breast cancer cells proliferation and migration

Zhang, Y., Yang, C., Zhang, M., Liu, H., Gong, C., Zhang, J., Xu, S., Zou, J., Kai, Y., & Li, Y. (2017) · Oncotarget · doi:10.18632/oncotarget.22491 · Cited by 32

Prognostic Roles of mRNA Expression of S100 in Non-Small-Cell Lung Cancer

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Trimodal distribution of arylamine N-acetyltransferase 1 mRNA in breast cancer tumors: association with overall survival and drug resistance

Minchin, R. F., & Butcher, N. J. (2018) · BMC Genomics · doi:10.1186/s12864-018-4894-4 · Cited by 30

P1-07-18: Expanding an Online Tool for Genome-Wide Validation of Survival-Associated Biomarkers in Breast and Ovarian Cancer Using Microarray Data of 3,862 Patients.

Győrffy, B., Lánczky, A., & Szállási, Z. (2011) · Cancer Research · doi:10.1158/0008-5472.sabcs11-p1-07-18 · Cited by 70

Online biomarker validation of survival-associated biomarkers in breast and ovarian cancer using microarray data of 3,862 patients.

Győrffy, B., Lánczky, A., & Szállási, Z. (2012) · Journal of Clinical Oncology · doi:10.1200/jco.2012.30.15_suppl.10571

Breast cancer classification and prognosis based on gene expression profiles from a population-based study

Sotiriou, C. P., Neo, S.-Y., McShane, L. M., Korn, E. L., Long, P. M., Jazaeri, A. A., Martiat, P., Fox, S. B., Harris, A. L., & Liu, E. T. (2003) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1732912100 · Cited by 2,024

Design and Multiseries Validation of a Web-Based Gene Expression Assay for Predicting Breast Cancer Recurrence and Patient Survival

van Laar, R. K. (2011) · Journal of Molecular Diagnostics · doi:10.1016/j.jmoldx.2010.12.003 · Cited by 12

bc-GenExMiner: an easy-to-use online platform for gene prognostic analyses in breast cancer

Jézéquel, P., Campone, M., Gouraud, W., Guérin‐Charbonnel, C., Leux, C., Ricolleau, G., & Campion, L. (2011) · Breast Cancer Research and Treatment · doi:10.1007/s10549-011-1457-7 · Cited by 410