An online survival analysis tool to rapidly assess the effect of 22,277 genes on breast cancer prognosis using microarray data of 1,809 patients

Nonparametric Estimation from Incomplete Observations

Kaplan, E. L., & Meier, P. (1992) · Springer series in statistics · doi:10.1007/978-1-4612-4380-9_25 · Cited by 45,239

Nonparametric Estimation from Incomplete Observations

Kaplan, E. L., & Meier, P. (1958) · Journal of the American Statistical Association · doi:10.1080/01621459.1958.10501452 · Cited by 39,158

A Multigene Assay to Predict Recurrence of Tamoxifen-Treated, Node-Negative Breast Cancer

Paik, S., Shak, S., Tang, G., Kim, C., Baker, J. B., Cronin, M. T., Baehner, F. L., Walker, M. G., Watson, D., Park, T., et al. (2004) · New England Journal of Medicine · doi:10.1056/nejmoa041588 · Cited by 6,321

affy—analysis of Affymetrix GeneChip data at the probe level

Gautier, L., Cope, L., Bolstad, B. M., & Irizarry, R. A. (2004) · Bioinformatics · doi:10.1093/bioinformatics/btg405 · Cited by 5,221

Gene-expression profiles to predict distant metastasis of lymph-node-negative primary breast cancer

Wang, Y., Klijn, J. G. M., Zhang, Y., Sieuwerts, A. M., Look, M. P., Yang, F., Talantov, D., Timmermans, M. A. M., Gelder, M. E. M., Yu, J. X., et al. (2005) · The Lancet · doi:10.1016/s0140-6736(05)17947-1 · Cited by 2,831

Gene Expression and Benefit of Chemotherapy in Women With Node-Negative, Estrogen Receptor–Positive Breast Cancer

Paik, S., Tang, G., Shak, S., Kim, C., Baker, J. B., Kim, W., Cronin, M. T., Baehner, F. L., Watson, D., Bryant, J., et al. (2006) · Journal of Clinical Oncology · doi:10.1200/jco.2005.04.7985 · Cited by 2,597

American Society of Clinical Oncology 2007 Update of Recommendations for the Use of Tumor Markers in Breast Cancer

Harris, L. N., Fritsche, H. A., Mennel, R. G., Norton, L., Ravdin, P. M., Taube, S. E., Somerfield, M. R., Hayes, D. F., & Bast, R. C. (2007) · Journal of Clinical Oncology · doi:10.1200/jco.2007.14.2364 · Cited by 2,234

The MicroArray Quality Control (MAQC) project shows inter- and intraplatform reproducibility of gene expression measurements

MAQC Consortium, Shi, L., Shi, L., Reid, L. H., Jones, W. D., Shippy, R., Warrington, J. A., Baker, S. C., Collins, P. J., de Longueville, F., et al. (2006) · Nature Biotechnology · doi:10.1038/nbt1239 · Cited by 2,126

Gene Expression Profiling in Breast Cancer: Understanding the Molecular Basis of Histologic Grade To Improve Prognosis

Sotiriou, C. P., Wirapati, P., Loi, S., Harris, A. L., Fox, S., Smeds, J., Nordgren, H., Farmer, P. J., Praz, V., Haibe‐Kains, B., et al. (2006) · JNCI Journal of the National Cancer Institute · doi:10.1093/jnci/djj052 · Cited by 2,050

Genes that mediate breast cancer metastasis to the brain

Bos, P. D., Zhang, X. H.-F., Nadal, C., Shu, W., Gomis, R. R., Nguyen, D. X., Minn, A. J., van de Vijver, M. J., Gerald, W. L., Foekens, J. A., et al. (2009) · Nature · doi:10.1038/nature08021 · Cited by 1,863

Proteomic Analysis of Urine to Identify Breast Cancer Biomarker Candidates Using a Label-Free LC-MS/MS Approach

Beretov, J., Wasinger, V. C., Millar, E. K. A., Schwartz, P. E., Graham, P., & Li, Y. (2015) · PLoS ONE · doi:10.1371/journal.pone.0141876 · Cited by 110

UTX inhibits EMT‐induced breast CSC properties by epigenetic repression of EMT genes in cooperation with LSD1 and HDAC1

Choi, H., Park, J., Park, M., Won, H., Joo, H.-S., Lee, C. H., Lee, J., & Kong, G. (2015) · EMBO Reports · doi:10.15252/embr.201540244 · Cited by 113

MCM2, MCM4, and MCM6 in Breast Cancer: Clinical Utility in Diagnosis and Prognosis

Issac, M. S. M., Yousef, E. M., Tahir, M. R., & Gaboury, L. A. (2019) · Neoplasia · doi:10.1016/j.neo.2019.07.011 · Cited by 113

Transglutaminase-2 facilitates extracellular vesicle-mediated establishment of the metastatic niche

Shinde, A. B., Paez, S. J., Libring, S., Hopkins, K., Solorio, L., & Wendt, M. K. (2020) · Oncogenesis · doi:10.1038/s41389-020-0204-5 · Cited by 115

Deregulation of UBE2C-mediated autophagy repression aggravates NSCLC progression

Guo, J., Wu, Y., Du, J., Yang, L., Chen, W., Gong, K., Dai, J., Miao, S., Jin, D., & Xi, S. (2018) · Oncogenesis · doi:10.1038/s41389-018-0054-6 · Cited by 115

Chemerin and Cancer

Treeck, O., Buechler, C., & Ortmann, O. (2019) · International Journal of Molecular Sciences · doi:10.3390/ijms20153750 · Cited by 112

Grhl2 Determines the Epithelial Phenotype of Breast Cancers and Promotes Tumor Progression

Xiang, X., Deng, Z., Zhuang, X., Ju, S., Mu, J., Jiang, H., Zhang, L., Yan, J., Miller, D., & Zhang, H. (2012) · PLoS ONE · doi:10.1371/journal.pone.0050781 · Cited by 111

MicroRNAs in the Imprinted DLK1-DIO3 Region Repress the Epithelial-to-Mesenchymal Transition by Targeting the TWIST1 Protein Signaling Network

Haga, C. L., & Phinney, D. G. (2012) · Journal of Biological Chemistry · doi:10.1074/jbc.m112.387761 · Cited by 120

LIMT is a novel metastasis inhibiting lncRNA suppressed by EGF and downregulated in aggressive breast cancer

Sas‐Chen, A., Aure, M. R. R., Leibovich, L., Carvalho, S., Enuka, Y., Körner, C., Polycarpou‐Schwarz, M., Lavi, S., Nevo, N., Kuznetsov, Y., et al. (2016) · EMBO Molecular Medicine · doi:10.15252/emmm.201606198 · Cited by 109

TFIIIC Binding to Alu Elements Controls Gene Expression via Chromatin Looping and Histone Acetylation

Ferrari, R., de Llobet, L., Vona, C. D., Dilly, F. L., Vidal, E., Lioutas, A., Quilez, J., Jochem, L., Cutts, E., Dieci, G., et al. (2019) · Molecular Cell · doi:10.1016/j.molcel.2019.10.020 · Cited by 111

The RNA-binding protein AKAP8 suppresses tumor metastasis by antagonizing EMT-associated alternative splicing

Hu, X., Harvey, S. E., Zheng, R., Lyu, J., Grzeskowiak, C. L., Powell, E., Piwnica-Worms, H. M., Scott, K. L., & Cheng, C. (2020) · Nature Communications · doi:10.1038/s41467-020-14304-1 · Cited by 109

Ligand-dependent genomic function of glucocorticoid receptor in triple-negative breast cancer

Chen, Z., Lan, X., Wu, D., Sunkel, B. D., Ye, Z., Huang, J., Liu, Z., Clinton, S. K., Jin, V. X., & Wang, Q. (2015) · Nature Communications · doi:10.1038/ncomms9323 · Cited by 110

Bulk and single-cell transcriptome profiling reveal the metabolic heterogeneity in human breast cancers

Yu, T., Ma, D., Liu, Y., Xiao, Y., Gong, Y., Jiang, Y., Shao, Z.-M., Hu, X., & Di, G. (2021) · Molecular Therapy · doi:10.1016/j.ymthe.2021.03.003 · Cited by 113

Androgen and AR contribute to breast cancer development and metastasis: an insight of mechanisms

Feng, J., Li, L., Zhang, N., Liu, J., Zhang, L., Gao, H., Wang, G., Li, Y., Zhang, Y., Li, X., et al. (2016) · Oncogene · doi:10.1038/onc.2016.432 · Cited by 109

Epigenetic and breast cancer therapy: Promising diagnostic and therapeutic applications

Sher, G., Salman, N. A., Khan, A. Q., Prabhu, K. S., Raza, A., Kuliński, M., Dermime, S., Haris, M., Junejo, K., & Shahab Uddin, M. S. (2020) · Seminars in Cancer Biology · doi:10.1016/j.semcancer.2020.08.009 · Cited by 114

Effect of CCL5 expression in the recruitment of immune cells in triple negative breast cancer

Araujo, J. M., Gomez, A. C., Aguilar, A., Salgado, R., Balko, J. M., Bravo, L., Doimi, F., Bretel, D., Morante, Z., Flores, C., et al. (2018) · Scientific Reports · doi:10.1038/s41598-018-23099-7 · Cited by 108

Long non-coding RNA metastasis associated in lung adenocarcinoma transcript 1 (MALAT1) interacts with estrogen receptor and predicted poor survival in breast cancer

Huang, N., Chi, Y., Xue, J., Liu, M.-Y., Huang, S., Mo, M., Zhou, S., & Wu, J. (2016) · Oncotarget · doi:10.18632/oncotarget.9364 · Cited by 108

CaMKK2 in myeloid cells is a key regulator of the immune-suppressive microenvironment in breast cancer

Racioppi, L., Nelson, E. R., Huang, W., Mukherjee, D., Lawrence, S. A., Lento, W. E., Masci, A. M., Jiao, Y., Park, S. H., York, B., et al. (2019) · Nature Communications · doi:10.1038/s41467-019-10424-5 · Cited by 104

Gene signatures and potential therapeutic targets of amino acid metabolism in estrogen receptor-positive breast cancer.

Wang, C., Chiao, C.-C., Phan, N. N., Li, C.-Y., Sun, Z., Jiang, J., Hung, J., Chen, Y., Yen, M., Weng, T.-Y., et al. (2020) · PubMed Central · Cited by 107

ACE2 correlated with immune infiltration serves as a prognostic biomarker in endometrial carcinoma and renal papillary cell carcinoma: implication for COVID-19

Yang, H. J., Li, H., Hu, S., & Zhou, Y. (2020) · Aging · doi:10.18632/aging.103100 · Cited by 108

miR-200a inhibits migration of triple-negative breast cancer cells through direct repression of the EPHA2 oncogene

Tsouko, E., Wang, J., Frigo, D. E., Aydoğdu, E., & Williams, C. (2015) · Carcinogenesis · doi:10.1093/carcin/bgv087 · Cited by 107

Meta-analysis of the global gene expression profile of triple-negative breast cancer identifies genes for the prognostication and treatment of aggressive breast cancer

Al-Ejeh, F., Simpson, P. T., Sanus, J. M., Klein, K., Kalimutho, M., Shi, W., Miranda, M., Kutasovic, J., Raghavendra, A., Madore, J., et al. (2014) · Oncogenesis · doi:10.1038/oncsis.2014.14 · Cited by 107

miR‐10b expression in breast cancer stem cells supports self‐renewal through negative PTEN regulation and sustained AKT activation

Bahena, I., Espinosa, M., Ceballos‐Cancino, G., Lizárraga, F., Campos‐Arroyo, D., Schwarz, A., Maldonado, V., & Meléndez-Zajgla, J. (2016) · EMBO Reports · doi:10.15252/embr.201540678 · Cited by 106

A high-resolution transcriptome map of cell cycle reveals novel connections between periodic genes and cancer

Dominguez, D., Tsai, Y., Gomez, N. C., Jha, D. K., Davis, I. J., & Wang, Z. (2016) · Cell Research · doi:10.1038/cr.2016.84 · Cited by 104

ZEB 1‐regulated inflammatory phenotype in breast cancer cells

Katsura, A., Tamura, Y., Hokari, S., Harada, M., Morikawa, M., Sakurai, T., Takahashi, K., Mizutani, A., Nishida, J., Yokoyama, Y., et al. (2017) · Molecular Oncology · doi:10.1002/1878-0261.12098 · Cited by 114

High expression of WTAP leads to poor prognosis of gastric cancer by influencing tumour‐associated T lymphocyte infiltration

Li, H., Su, Q., Li, B., Lan, L., Wang, C., Li, W., Wang, G., Chen, W., He, Y., & Zhang, C. (2020) · Journal of Cellular and Molecular Medicine · doi:10.1111/jcmm.15104 · Cited by 106

Loss of ELF5–FBXW7 stabilizes IFNGR1 to promote the growth and metastasis of triple-negative breast cancer through interferon-γ signalling

Singh, S., Kumar, S., Srivastava, R. K., Nandi, A., Thacker, G., Murali, H., Kim, S., Baldeon, M. A., Tobias, J. W., Blanco, M. A., et al. (2020) · Nature Cell Biology · doi:10.1038/s41556-020-0495-y · Cited by 106

Adenylate Kinase 4 Modulates the Resistance of Breast Cancer Cells to Tamoxifen through an m6A-Based Epitranscriptomic Mechanism

Liu, X., Gonzalez, G. M., Dai, X., Miao, W., Yuan, J. J., Huang, M., Bade, D., Li, L., Sun, Y., & Wang, Y. (2020) · Molecular Therapy · doi:10.1016/j.ymthe.2020.09.007 · Cited by 105

Inhibition of BMP signaling suppresses metastasis in mammary cancer

Owens, P., Pickup, M. W., Novitskiy, S. V., Giltnane, J. M., Gorska, A. E., Hopkins, C. R., Hong, C. C., & Moses, H. L. (2014) · Oncogene · doi:10.1038/onc.2014.189 · Cited by 106

GALNT14 promotes lung-specific breast cancer metastasis by modulating self-renewal and interaction with the lung microenvironment

Song, K.-H., Park, M. S., Nandu, T. S., Gadad, S. S., Kim, S.-C., & Kim, M. (2016) · Nature Communications · doi:10.1038/ncomms13796 · Cited by 106

Stress granule-associated protein G3BP2 regulates breast tumor initiation

Gupta, N., Badeaux, M. D., Liu, Y., Naxerova, K., Sgroi, D. C., Munn, L. L., Jain, R. K., & Garkavtsev, I. (2017) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1525387114 · Cited by 106

Protein kinase C as a tumor suppressor

Newton, A. C. (2017) · Seminars in Cancer Biology · doi:10.1016/j.semcancer.2017.04.017 · Cited by 106

miR‐200/375 control epithelial plasticity‐associated alternative splicing by repressing the RNA‐binding protein Quaking

Pillman, K. A., Phillips, C. A., Roslan, S., Toubia, J., Dredge, B. K., Bert, A. G., Lumb, R., Neumann, D., Li, X., Conn, S. J., et al. (2018) · The EMBO Journal · doi:10.15252/embj.201899016 · Cited by 107

Notch Signaling Regulates Mitochondrial Metabolism and NF-κB Activity in Triple-Negative Breast Cancer Cells via IKKα-Dependent Non-canonical Pathways

Hossain, F. M., Sorrentino, C., Uçar, D. A., Peng, Y., Matossian, M. D., Wyczechowska, D. D., Crabtree, J. S., Zabaleta, J., Morello, S., Valle, L. D., et al. (2018) · Frontiers in Oncology · doi:10.3389/fonc.2018.00575 · Cited by 106

A Gene Expression Signature from Human Breast Cancer Cells with Acquired Hormone Independence Identifies MYC as a Mediator of Antiestrogen Resistance

Miller, T. W., Balko, J. M., Ghazoui, Z. F., Dunbier, A. K., Anderson, H., Dowsett, M., Gonzalez-Angulo, A. M., Mills, G. B., Miller, W. R., Wu, H., et al. (2011) · Clinical Cancer Research · doi:10.1158/1078-0432.ccr-10-2567 · Cited by 104

The receptor tyrosine kinase EphA2 promotes glutamine metabolism in tumors by activating the transcriptional coactivators YAP and TAZ

Edwards, D. N., Ngwa, V. M., Wang, S., Shiuan, E. F., Brantley‐Sieders, D. M., Kim, L. C., Reynolds, A. B., & Chen, J. (2017) · Science Signaling · doi:10.1126/scisignal.aan4667 · Cited by 109

Membrane associated collagen XIII promotes cancer metastasis and enhances anoikis resistance

Zhang, H., Fredericks, T. I., Xiong, G., Qi, Y., Rychahou, P. G., Li, J., Pihlajaniemi, T. A., Xu, W., & Xu, R. (2018) · Breast Cancer Research · doi:10.1186/s13058-018-1030-y · Cited by 105

HNRNPA2/B1 is upregulated in endocrine-resistant LCC9 breast cancer cells and alters the miRNA transcriptome when overexpressed in MCF-7 cells

Klinge, C. M., Piell, K. M., Tooley, C. E. S., & Rouchka, E. C. (2019) · Scientific Reports · doi:10.1038/s41598-019-45636-8 · Cited by 105

Inhibition of 6-phosphofructo-2-kinase (PFKFB3) suppresses glucose metabolism and the growth of HER2+ breast cancer

O’Neal, J., Clem, A. L., Reynolds, L., Dougherty, S. M., Imbert-Fernandez, Y., Telang, S., Chesney, J. A., & Clem, B. F. (2016) · Breast Cancer Research and Treatment · doi:10.1007/s10549-016-3968-8 · Cited by 105

Normal and cancerous mammary stem cells evade interferon-induced constraint through the miR-199a–LCOR axis

Celià-Terrassa, T., Liu, D. D., Choudhury, A., Hang, X., Wei, Y., Zamalloa, J., Alfaro‐Aco, R., Chakrabarti, R., Jiang, Y., Koh, B. I., et al. (2017) · Nature Cell Biology · doi:10.1038/ncb3533 · Cited by 105

The expression profile and prognostic significance of eukaryotic translation elongation factors in different cancers

Hassan, M. K., Kumar, D., Naik, M., & Dixit, M. (2018) · PLoS ONE · doi:10.1371/journal.pone.0191377 · Cited by 104

Phosphoglycerate mutase 1 promotes cancer cell migration independent of its metabolic activity

Zhang, D., Jin, N., Sun, W., Li, X., Liu, B., Xie, Z., Qu, J., Xu, J., Yang, X., Su, Y., et al. (2016) · Oncogene · doi:10.1038/onc.2016.446 · Cited by 103

NDRG1 regulates neutral lipid metabolism in breast cancer cells

Sevinsky, C. J., Khan, F., Kokabee, L., Darehshouri, A., Maddipati, K. R., & Conklin, D. S. (2018) · Breast Cancer Research · doi:10.1186/s13058-018-0980-4 · Cited by 103

Comprehensive Review of Web Servers and Bioinformatics Tools for Cancer Prognosis Analysis

Zheng, H., Zhang, G., Zhang, L., Wang, Q., Li, H., Han, Y., Xie, L., Yan, Z., Li, Y., An, Y., et al. (2020) · Frontiers in Oncology · doi:10.3389/fonc.2020.00068 · Cited by 103

The aryl hydrocarbon receptor mediates raloxifene-induced apoptosis in estrogen receptor-negative hepatoma and breast cancer cells

O’Donnell, E. F., Koch, D. C., Bisson, W. H., Jang, H. S., & Kolluri, S. K. (2014) · Cell Death and Disease · doi:10.1038/cddis.2013.549 · Cited by 105

Oncogenic Kinase–Induced PKM2 Tyrosine 105 Phosphorylation Converts Nononcogenic PKM2 to a Tumor Promoter and Induces Cancer Stem–like Cells

Zhou, Z., Li, M., Zhang, L., Zhao, H., Şahin, Ö., Chen, J., Zhao, J. J., Songyang, Z., & Yu, D. (2018) · Cancer Research · doi:10.1158/0008-5472.can-17-2726 · Cited by 102

NOTCH-mediated non-cell autonomous regulation of chromatin structure during senescence

Parry, A. J., Hoare, M., Bihary, D., Hänsel-Hertsch, R., Smith, S., Tomimatsu, K., Mannion, E., Smith, A., D’Santos, P., Russell, I. A., et al. (2018) · Nature Communications · doi:10.1038/s41467-018-04283-9 · Cited by 102

Treatment of Triple-Negative Breast Cancer with TORC1/2 Inhibitors Sustains a Drug-Resistant and Notch-Dependent Cancer Stem Cell Population

Bhola, N. E., Jansen, V. M., Koch, J. P., Li, H., Formisano, L., Williams, J. A., Grandis, J. R., & Arteaga, C. L. (2015) · Cancer Research · doi:10.1158/0008-5472.can-15-1640-t · Cited by 103

Thermal proteome profiling of breast cancer cells reveals proteasomal activation by CDK4/6 inhibitor palbociclib

Miettinen, T. P., Peltier, J., Härtlová, A., Gierliński, M., Jansen, V. M., Trost, M., & Björklund, M. (2018) · The EMBO Journal · doi:10.15252/embj.201798359 · Cited by 106

Overexpression of ASPM, CDC20, and TTK Confer a Poorer Prognosis in Breast Cancer Identified by Gene Co-expression Network Analysis

Tang, J., Lü, M., Cui, Q., Zhang, D., Kong, D., Liao, X. H., Ren, J., Gong, Y. Q., & Wu, G. (2019) · Frontiers in Oncology · doi:10.3389/fonc.2019.00310 · Cited by 101

Activation of the IFN Signaling Pathway is Associated with Resistance to CDK4/6 Inhibitors and Immune Checkpoint Activation in ER-Positive Breast Cancer

Angelis, C. D., Fu, X., Cataldo, M. L., Nardone, A., Pereira, R., Veeraraghavan, J., Nanda, S., Qin, L., Sethunath, V., Wang, T., et al. (2021) · Clinical Cancer Research · doi:10.1158/1078-0432.ccr-19-4191 · Cited by 105

Activation of KRAS promotes the mesenchymal features of basal-type breast cancer

Kim, R.-K., Suh, Y., Yoo, K.-C., Cui, Y., Kim, H., Kim, M.-J., Kim, I. G., & Lee, S.-J. (2015) · Experimental & Molecular Medicine · doi:10.1038/emm.2014.99 · Cited by 97

Distinct expression of CDCA3, CDCA5, and CDCA8 leads to shorter relapse free survival in breast cancer patient

Phan, N. N., Wang, C., Li, K.-L., Chen, C., Chiao, C.-C., Yu, H.-G., Huang, P.-L., & Lin, Y.-C. (2018) · Oncotarget · doi:10.18632/oncotarget.24059 · Cited by 100

Tumor-Infiltrating B Lymphocyte Profiling Identifies IgG-Biased, Clonally Expanded Prognostic Phenotypes in Triple-Negative Breast Cancer

Harris, R. J. C., Cheung, A., Ng, J. C.-F., Laddach, R., Chenoweth, A. M., Crescioli, S., Fittall, M. W., Dominguez-Rodriguez, D., Roberts, J., Levi, D., et al. (2021) · Cancer Research · doi:10.1158/0008-5472.can-20-3773 · Cited by 100

The atypical ubiquitin ligase RNF31 stabilizes estrogen receptor α and modulates estrogen-stimulated breast cancer cell proliferation

Zhu, J., Zhao, C., Razavirad, A., Zhuang, T., Jonsson, P., Liang, N., Williams, C., Lin, C.-Y., Qiao, Y., Zendehdel, K., et al. (2014) · Oncogene · doi:10.1038/onc.2013.573 · Cited by 99

CEP55 is a determinant of cell fate during perturbed mitosis in breast cancer

Kalimutho, M., Sinha, D., Jeffery, J., Nones, K., Srihari, S., Fernando, W., Duijf, P. H. G., Vennin, C., Raninga, P. V., Nanayakkara, D. M., et al. (2018) · EMBO Molecular Medicine · doi:10.15252/emmm.201708566 · Cited by 100

Homeostatic membrane tension constrains cancer cell dissemination by counteracting BAR protein assembly

Tsujita, K., Satow, R., Asada, S., Nakamura, Y., Arnes, L., Sako, K., Fujita, Y., Fukami, K., & Itoh, T. (2021) · Nature Communications · doi:10.1038/s41467-021-26156-4 · Cited by 101

UCP2 inhibition sensitizes breast cancer cells to therapeutic agents by increasing oxidative stress

Pons, D. G., Nadal‐Serrano, M., Torrens‐Mas, M., Valle, A., Oliver, J., & Roca, P. (2015) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2015.04.032 · Cited by 104

Targeting EphA2 impairs cell cycle progression and growth of basal-like/triple-negative breast cancers

Song, W., Hwang, Y., Youngblood, V., Cook, R. S., Balko, J. M., Chen, J., & Brantley‐Sieders, D. M. (2017) · Oncogene · doi:10.1038/onc.2017.170 · Cited by 98

Mesenchymal Stem/Stromal Cell Engulfment Reveals Metastatic Advantage in Breast Cancer

Chen, Y., González, M. E., Burman, B., Zhao, X., Anwar, T., Tran, M., Medhora, N., Hiziroglu, A. B., Lee, W., Cheng, Y.-H., et al. (2019) · Cell Reports · doi:10.1016/j.celrep.2019.05.084 · Cited by 97

Significant prognostic values of differentially expressed-aberrantly methylated hub genes in breast cancer

Qi, L., Zhou, B., Chen, J., Hu, W., Bai, R., Ye, C., Weng, X., & Zheng, S. S. (2019) · Journal of Cancer · doi:10.7150/jca.33433 · Cited by 98

MaTAR25 lncRNA regulates the Tensin1 gene to impact breast cancer progression

Chang, K.-C., Diermeier, S. D., Yu, A. T., Brine, L., Russo, S., Bhatia, S., Alsudani, H., Kostroff, K. M., Bhuiya, T. A., Brogi, E., et al. (2020) · Nature Communications · doi:10.1038/s41467-020-20207-y · Cited by 98

Sialic Acid Metabolism: A Key Player in Breast Cancer Metastasis Revealed by Metabolomics

Teoh, S. T., Ogrodzinski, M. P., Ross, C. R., Hunter, K. W., & Lunt, S. Y. (2018) · Frontiers in Oncology · doi:10.3389/fonc.2018.00174 · Cited by 100

Cell cycle and aging, morphogenesis, and response to stimuli genes are individualized biomarkers of glioblastoma progression and survival

Serão, N. V. L., Delfino, K. R., Southey, B. R., Beever, J. E., & Rodriguez‐Zas, S. L. (2011) · BMC Medical Genomics · doi:10.1186/1755-8794-4-49 · Cited by 97

Autocrine HBEGF expression promotes breast cancer intravasation, metastasis and macrophage-independent invasion in vivo

Zhou, Z., Sharma, V. P., Beaty, B. T., Roh‐Johnson, M., Peterson, E. A., van Rooijen, N., Kenny, P. A., Wiley, H. S., Condeelis, J. S., & Segall, J. E. (2013) · Oncogene · doi:10.1038/onc.2013.363 · Cited by 101

Tumor cell expression of MMP3 as a prognostic factor for poor survival in pancreatic, pulmonary, and mammary carcinoma

Mehner, C., Miller, E. E., Nassar, A., Bamlet, W. R., Radisky, E. S., & Radisky, D. C. (2015) · Genes & Cancer · doi:10.18632/genesandcancer.90 · Cited by 99

TRPC1 is a differential regulator of hypoxia-mediated events and Akt signalling in PTEN-deficient breast cancer cells

Azimi, I., Milevskiy, M. J. G., Kaemmerer, E., Turner, D., Yapa, K. T. D. S., Brown, M. A., Thompson, E. W., Roberts‐Thomson, S. J., & Monteith, G. R. (2017) · Journal of Cell Science · doi:10.1242/jcs.196659 · Cited by 97

LncRNA H19 is a major mediator of doxorubicin chemoresistance in breast cancer cells through a cullin4A-MDR1 pathway

Zhu, Q.-N., Wang, G., Guo, Y., Peng, Y., Zhang, R., Deng, J., Li, Z., & Zhu, Y. (2017) · Oncotarget · doi:10.18632/oncotarget.21121 · Cited by 97

Molecular Portrait of Hypoxia in Breast Cancer: A Prognostic Signature and Novel HIF-Regulated Genes

Ye, I. C., Fertig, E. J., DiGiacomo, J. W., Considine, M., Godet, I., & Gilkes, D. M. (2018) · Molecular Cancer Research · doi:10.1158/1541-7786.mcr-18-0345 · Cited by 96

CXCL17-derived CD11b+Gr-1+ myeloid-derived suppressor cells contribute to lung metastasis of breast cancer through platelet-derived growth factor-BB

Hsu, Y., Yen, M., Chang, W., Tsai, P.-H., Pan, Y., Liao, S., & Kuo, P. (2019) · Breast Cancer Research · doi:10.1186/s13058-019-1114-3 · Cited by 97

Identification of microRNA biomarkers in the blood of breast cancer patients based on microRNA profiling

Zhang, K., Wang, Y., Wang, Y., Song, Y. M., Zhu, J., Si, P., & Ma, R. (2017) · Gene · doi:10.1016/j.gene.2017.03.038 · Cited by 96

Mechano-Signal Transduction in Mesenchymal Stem Cells Induces Prosaposin Secretion to Drive the Proliferation of Breast Cancer Cells

Ishihara, S., Inman, D. R., Li, W., Ponik, S. M., & Keely, P. J. (2017) · Cancer Research · doi:10.1158/0008-5472.can-17-0569 · Cited by 95

Estrogen-dependent DLL1-mediated Notch signaling promotes luminal breast cancer

Kumar, S., Srivastav, R. K., Wilkes, D. W., Ross, T., Kim, S., Kowalski, J., Chatla, S., Zhang, Q. H., Nayak, A., Guha, M., et al. (2018) · Oncogene · doi:10.1038/s41388-018-0562-z · Cited by 96

Prognostic characterization of OAS1/OAS2/OAS3/OASL in breast cancer

Zhang, Y., & Yu, C. (2020) · BMC Cancer · doi:10.1186/s12885-020-07034-6 · Cited by 96

Global secretome analysis identifies novel mediators of bone metastasis

Blanco, M. A., LeRoy, G., Khan, Z., Alečković, M., Zee, B. M., Garcia, B. A., & Kang, Y. (2012) · Cell Research · doi:10.1038/cr.2012.89 · Cited by 93

Deubiquitinase USP20 promotes breast cancer metastasis by stabilizing SNAI2Preprint

Li, W., Shen, M., Jiang, Y., Zhang, R., Zheng, H., Wei, Y., Shao, Z., & Kang, Y. (2020) · Genes & Development · doi:10.1101/gad.339804.120 · Cited by 93

RecurrenceOnline: an online analysis tool to determine breast cancer recurrence and hormone receptor status using microarray data

Győrffy, B., Benke, Z., Lánczky, A., Balázs, B., Szállási, Z., Tı́már, J., & Schäfer, R. (2011) · Breast Cancer Research and Treatment · doi:10.1007/s10549-011-1676-y · Cited by 98

SMYD3 promotes the epithelial–mesenchymal transition in breast cancer

Fenizia, C., Bottino, C., Corbetta, S., Fittipaldi, R., Floris, P., Gaudenzi, G., Carra, S., Cotelli, F., Vitale, G., & Caretti, G. (2018) · Nucleic Acids Research · doi:10.1093/nar/gky1221 · Cited by 92

Mitohormesis Primes Tumor Invasion and Metastasis

Kenny, T. C., Craig, A. J., Villanueva, A., & Germain, D. (2019) · Cell Reports · doi:10.1016/j.celrep.2019.04.095 · Cited by 102

Estrogen receptor signaling is reprogrammed during breast tumorigenesis

Chi, D., Singhal, H., Li, L., Xiao, T., Liu, W., Pun, M. J., Jeselsohn, R. M., He, H., Lim, E., Vadhi, R., et al. (2019) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1819155116 · Cited by 94

Insulin-like growth factor binding protein-3 (IGFBP-3): Novel ligands mediate unexpected functions

Baxter, R. C. (2013) · Journal of Cell Communication and Signaling · doi:10.1007/s12079-013-0203-9 · Cited by 95

Vangl1 and Vangl2: planar cell polarity components with a developing role in cancer

Hatakeyama, J., Wald, J. H., Printsev, I., Ho, H. H., & Carraway, K. L. (2014) · Endocrine Related Cancer · doi:10.1530/erc-14-0141 · Cited by 96

Mitochondrial markers predict recurrence, metastasis and tamoxifen-resistance in breast cancer patients: Early detection of treatment failure with companion diagnostics

Sotgia, F., Fiorillo, M., & Lisanti, M. P. (2017) · Oncotarget · doi:10.18632/oncotarget.19612 · Cited by 96

Development and validation of serum exosomal microRNAs as diagnostic and prognostic biomarkers for hepatocellular carcinoma

Xue, X., Zhao, Y., Wang, X., Qin, L., & Hu, R. (2018) · Journal of Cellular Biochemistry · doi:10.1002/jcb.27165 · Cited by 95

TRIM59 promotes breast cancer motility by suppressing p62-selective autophagic degradation of PDCD10

Tan, P., Ye, Y., He, L., Xie, J., Ji, J., Ma, G., Pan, H., Han, L., Han, W., & Zhou, Y. (2018) · PLoS Biology · doi:10.1371/journal.pbio.3000051 · Cited by 96

Immunotherapy of triple-negative breast cancer with cathepsin D-targeting antibodies

Ashraf, Y., Mansouri, H., Laurent‐Matha, V., Alcaraz, L. B., Roger, P., Guiu, S., Derocq, D., Robin, G., Michaud, H., Delpech, H., et al. (2019) · Journal for ImmunoTherapy of Cancer · doi:10.1186/s40425-019-0498-z · Cited by 94

Breast Cancer Classification Based on Proteotypes Obtained by SWATH Mass Spectrometry

Bouchal, P., Schubert, O. T., Faktor, J., Capkova, L., Imrichova, H., Zoufalova, K., Paralova, V., Hrstka, R., Liu, Y., Ebhardt, H. A., et al. (2019) · Cell Reports · doi:10.1016/j.celrep.2019.06.046 · Cited by 94

Adipocyte-derived exosomes may promote breast cancer progression in type 2 diabetes

Jafari, N., Kolla, M., Meshulam, T., Shafran, J. S., Qiu, Y., Casey, A. N., Pompa, I. R., Ennis, C. S., Mazzeo, C., Rabhi, N., et al. (2021) · Science Signaling · doi:10.1126/scisignal.abj2807 · Cited by 94

Regulatory role of resveratrol, a microRNA-controlling compound, in HNRNPA1 expression, which is associated with poor prognosis in breast cancer

Otsuka, K., Yamamoto, Y., & Ochiya, T. (2018) · Oncotarget · doi:10.18632/oncotarget.25339 · Cited by 96

Heat shock proteins create a signature to predict the clinical outcome in breast cancer

Klimczak, M., Biecek, P., Żylicz, M., & Żylicz, M. (2019) · Scientific Reports · doi:10.1038/s41598-019-43556-1 · Cited by 93

Cyclin-dependent kinases in breast cancer: expression pattern and therapeutic implications

Sofi, S., Mehraj, U., Qayoom, H., Aisha, S., Asdaq, S. M. B., Almilaibary, A., & Mir, M. A. (2022) · Medical Oncology · doi:10.1007/s12032-022-01731-x · Cited by 93

The GRHL2/ZEB Feedback Loop-A Key Axis in the Regulation of EMT in Breast Cancer

Mooney, S. M., Talebian, V., Jolly, M. K., Jia, D., Gromala, M., Levine, H., & McConkey, B. J. (2017) · Journal of Cellular Biochemistry · doi:10.1002/jcb.25974 · Cited by 92

Interferon-Stimulated Genes Are Involved in Cross-resistance to Radiotherapy in Tamoxifen-Resistant Breast Cancer

Post, A. E. M., Smid, M., Nagelkerke, A., Martens, J. W. M., Bussink, J., Sweep, F. C. G. J., & Span, P. N. (2018) · Clinical Cancer Research · doi:10.1158/1078-0432.ccr-17-2551 · Cited by 92

Hypoxia promotes breast cancer cell invasion through HIF-1α-mediated up-regulation of the invadopodial actin bundling protein CSRP2

Hoffmann, C., Mao, X., Brown-Clay, J. D., Moreau, F., Absi, A. A., Wurzer, H., Sousa, B., Schmitt, F. C., Berchem, G., Janji, B., et al. (2018) · Scientific Reports · doi:10.1038/s41598-018-28637-x · Cited by 92

Targeting the Immunomodulatory CD73/Adenosine System to Improve the Therapeutic Gain of Radiotherapy

de Leve, S., Wirsdörfer, F., & Jendrossek, V. (2019) · Frontiers in Immunology · doi:10.3389/fimmu.2019.00698 · Cited by 93

Correlations of Differentially Expressed Gap Junction Connexins Cx26, Cx30, Cx32, Cx43 and Cx46 with Breast Cancer Progression and Prognosis

Teleki, I., Szász, A. M., Maros, M. E., Győrffy, B., Kulka, J., Meggyesházi, N., Kiszner, G., Balla, P., Aliz, S., & Krenács, T. (2014) · PLoS ONE · doi:10.1371/journal.pone.0112541 · Cited by 91

Inhibition of histone methyltransferase DOT1L silences ERα gene and blocks proliferation of antiestrogen-resistant breast cancer cells

Nassa, G., Salvati, A., Tarallo, R., Gigantino, V., Alexandrova, E., Memoli, D., Sellitto, A., Rizzo, F. M., Malanga, D., Mirante, T., et al. (2019) · Science Advances · doi:10.1126/sciadv.aav5590 · Cited by 93

Ablation of miR-10b Suppresses Oncogene-Induced Mammary Tumorigenesis and Metastasis and Reactivates Tumor-Suppressive Pathways

Kim, J., Siverly, A. N., Chen, D., Wang, M., Yuan, Y., Wang, Y., Lee, H., Zhang, J., Muller, W. J., Liang, H., et al. (2016) · Cancer Research · doi:10.1158/0008-5472.can-16-1571 · Cited by 96

Distinct prognostic values of S100 mRNA expression in breast cancer

Zhang, S., Wang, Z., Liu, W., Lei, R., Shan, J., Li, L., & Wang, X. (2017) · Scientific Reports · doi:10.1038/srep39786 · Cited by 90

MicroRNA-34 family in breast cancer: from research to therapeutic potential

İmani, S., Wu, R., & Fu, J. (2018) · Journal of Cancer · doi:10.7150/jca.25576 · Cited by 92

P1-07-18: Expanding an Online Tool for Genome-Wide Validation of Survival-Associated Biomarkers in Breast and Ovarian Cancer Using Microarray Data of 3,862 Patients.

Győrffy, B., Lánczky, A., & Szállási, Z. (2011) · Cancer Research · doi:10.1158/0008-5472.sabcs11-p1-07-18 · Cited by 70

Online biomarker validation of survival-associated biomarkers in breast and ovarian cancer using microarray data of 3,862 patients.

Győrffy, B., Lánczky, A., & Szállási, Z. (2012) · Journal of Clinical Oncology · doi:10.1200/jco.2012.30.15_suppl.10571

Breast cancer classification and prognosis based on gene expression profiles from a population-based study

Sotiriou, C. P., Neo, S.-Y., McShane, L. M., Korn, E. L., Long, P. M., Jazaeri, A. A., Martiat, P., Fox, S. B., Harris, A. L., & Liu, E. T. (2003) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1732912100 · Cited by 2,024

Design and Multiseries Validation of a Web-Based Gene Expression Assay for Predicting Breast Cancer Recurrence and Patient Survival

van Laar, R. K. (2011) · Journal of Molecular Diagnostics · doi:10.1016/j.jmoldx.2010.12.003 · Cited by 12

bc-GenExMiner: an easy-to-use online platform for gene prognostic analyses in breast cancer

Jézéquel, P., Campone, M., Gouraud, W., Guérin‐Charbonnel, C., Leux, C., Ricolleau, G., & Campion, L. (2011) · Breast Cancer Research and Treatment · doi:10.1007/s10549-011-1457-7 · Cited by 410