The DOI matches its Crossref record; 149 of the 149 references it cites were found in a registry or an index.
Colorectal cancer: a comprehensive review of carcinogenesis, diagnosis, and novel strategies for classified treatments
Open accessAbstract
Colorectal cancer is the third most common and the second deadliest cancer worldwide. To date, colorectal cancer becomes one of the most important challenges of the health system in many countries. Since the clinical symptoms of this cancer appear in the final stages of the disease and there is a significant golden time between the formation of polyps and the onset of cancer, early diagnosis can play a significant role in reducing mortality. Today, in addition to colonoscopy, minimally invasive methods such as liquid biopsy have received much attention. The treatment of this complex disease has been mostly based on traditional treatments including surgery, radiotherapy, and chemotherapy; the high mortality rate indicates a lack of success for current treatment methods. Moreover, disease recurrence is another problem of traditional treatments. Recently, new approaches such as targeted therapy, immunotherapy, and nanomedicine have opened new doors for cancer treatment, some of which have already entered the market, and many methods have shown promising results in clinical trials. The success of immunotherapy in the treatment of refractory disease, the introduction of these methods into neoadjuvant therapy, and the successful results in tumor shrinkage without surgery have made immunotherapy a tough competitor for conventional treatments. It seems that the combination of those methods with such targeted therapies will go through promising changes in the future of colorectal cancer treatment.
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1 retracted
RETRACTED: CAR-NK Cell: A New Paradigm in Tumor Immunotherapy
Marofi, F., Al-Awad, A. S., Rahman, H. S., Markov, A. A., Abdelbasset, W. K., Enina, Y. I., Mahmoodi, M., Hassanzadeh, A., Yazdanifar, M., Chartrand, M. S., et al. (2021) · Frontiers in Oncology · doi:10.3389/fonc.2021.673276 · Cited by 96
RetractedImmunotherapy in colorectal cancer: Rationale, challenges and potential
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Consensus guidelines for the definition, detection and interpretation of immunogenic cell death
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Cited by
An updated landscape on nanopharmaceutical delivery for mitigation of colon cancer
Shahzad, M., Hameed, H., Amjad, A., Khan, M. A., Qureshi, I. S., Hameed, A., Saeed, A., & Munir, R. (2025) · Naunyn-Schmiedeberg's Archives of Pharmacology · doi:10.1007/s00210-024-03482-0 · Cited by 7
Metadata
- Authors
- Abedizadeh, R., Majidi, F., Khorasani, H. R., Abedi, H., & Sabour, D.
- Venue
- Cancer and Metastasis Reviews
- Published
- 2023-12-19
- Volume
- 43
- Issue
- 2
- Pages
- 729-753
- ISSN
- 0167-7659 (ISSN-L)
- 1573-7233
- OpenAlex
- W4389977077
- Cited by
- 293
- References
- 149
- FWCI
- 14.09
- Type
- journal article
- Language
- en
- Open access
- hybrid
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- CoChat. (2026). Citation check: Colorectal cancer: a comprehensive review of carcinogenesis, diagnosis, and novel strategies for classified treatments. https://app.cochat.ai/papers/10.1007/s10555-023-10158-3
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- Abedizadeh, R., Majidi, F., Khorasani, H. R., Abedi, H., & Sabour, D. (2024). Colorectal cancer: a comprehensive review of carcinogenesis, diagnosis, and novel strategies for classified treatments. Cancer and Metastasis Reviews. https://doi.org/10.1007/s10555-023-10158-3
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
