The DOI matches its Crossref record; 332 of the 332 references it cites were found in a registry or an index.
Consensus guidelines for the definition, detection and interpretation of immunogenic cell death
Open accessAbstract
Cells succumbing to stress via regulated cell death (RCD) can initiate an adaptive immune response associated with immunological memory, provided they display sufficient antigenicity and adjuvanticity. Moreover, multiple intracellular and microenvironmental features determine the propensity of RCD to drive adaptive immunity. Here, we provide an updated operational definition of immunogenic cell death (ICD), discuss the key factors that dictate the ability of dying cells to drive an adaptive immune response, summarize experimental assays that are currently available for the assessment of ICD in vitro and in vivo, and formulate guidelines for their interpretation.
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Metadata
- Authors
- Galluzzi, L., Vitale, I., Warren, S., Adjemian, S., Agostinis, P., Martinez, A. B., Chan, T. A., Coukos, G., Demaria, S., Deutsch, E., Draganov, D., Edelson, R. L., Formenti, S. C., Fucikova, J., Gabriele, L., Gaipl, U. S., Gameiro, S. R., Garg, A. D., Golden, E., Han, J., Harrington, K. J., Hemminki, A., Hodge, J. W., Hossain, D. M. S., Illidge, T., Karin, M., Kaufman, H. L., Kepp, O., Kroemer, G., Lasarte, J. J., Loi, S., Lotze, M. T., Manic, G., Merghoub, T., Melcher, A. A., Mossman, K. L., Prosper, F., Rekdal, Ø., Rescigno, M., Riganti, C., Sistigu, A., Smyth, M. J., Spisek, R., Stagg, J., Strauss, B. E., Tang, D., Tatsuno, K., van Gool, S. W., Vandenabeele, P., Yamazaki, T., Zamarin, D., Zitvogel, L., Cesano, A., & Marincola, F. M.
- Venue
- Journal for ImmunoTherapy of Cancer
- Publisher
- BMJ
- Published
- 2020-03
- Volume
- 8
- Issue
- 1
- Pages
- e000337
- ISSN
- 2051-1426 (ISSN-L)
- OpenAlex
- W3011642937
- Cited by
- 1,119
- References
- 332
- FWCI
- 45.59
- Type
- journal article
- Language
- en
- Open access
- gold
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- Galluzzi, L., Vitale, I., Warren, S., Adjemian, S., Agostinis, P., Martinez, A. B., Chan, T. A., Coukos, G., Demaria, S., Deutsch, E., Draganov, D., Edelson, R. L., Formenti, S. C., Fucikova, J., Gabriele, L., Gaipl, U. S., Gameiro, S. R., Garg, A. D., Golden, E., . . . Marincola, F. M. (2020). Consensus guidelines for the definition, detection and interpretation of immunogenic cell death. Journal for ImmunoTherapy of Cancer. https://doi.org/10.1136/jitc-2019-000337
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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