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Predicting Developmental Status from 12 to 24 Months in Infants at Risk for Autism Spectrum Disorder: A Preliminary Report

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Macari, Suzanne L., Campbell, Daniel, Gengoux, Grace W., Saulnier, Celine A., Klin, Ami J., Chawarska, Katarzyna·2012·Journal of Autism and Developmental Disorders

DOI 10.1007/s10803-012-1521-0PMC PMC3565427

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Abstract

The study examined whether performance profiles on individual items of the Toddler Module of the Autism Diagnostic Observation Schedule at 12 months are associated with developmental status at 24 months in infants at high and low risk for developing Autism Spectrum Disorder (ASD). A nonparametric decision-tree learning algorithm identified sets of 12-month predictors of developmental status at 24 months. Results suggest that identification of infants who are likely to exhibit symptoms of ASD at 24 months is complicated by variable patterns of symptom emergence. Fine-grained analyses linking specific profiles of strengths and deficits with specific patterns of symptom emergence will be necessary for further refinement of screening and diagnostic instruments for ASD in infancy.

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Peer Reviewed Title: Investigation of Early Symptom Presentation in Children Under Age Three with Risk for Autism
Catherine, E. (2014)

Authors: Macari, S. L., Campbell, D., Gengoux, G. W., Saulnier, C. A., Klin, A. J., & Chawarska, K.
Affiliations: Yale University (US)
Emory University (US)
Corresponding author: Macari, Suzanne L.
ORCID: Macari, Suzanne L.
Gengoux, Grace W.
Saulnier, Celine A.
Chawarska, Katarzyna
Venue: Journal of Autism and Developmental Disorders
Publisher: Springer Science and Business Media LLC
Published: 2012-04-07
Volume: 42
Issue: 12
Pages: 2636-2647
ISSN: 0162-3257 (ISSN-L)
1573-3432
DOI: 10.1007/s10803-012-1521-0
PMC: PMC3565427
OpenAlex: W2030278404
Cited by: 116
References: 57
Citations by year: 2025: 1 · 2024: 3 · 2023: 1 · 2022: 5 · 2021: 4 · 2020: 43 · 2019: 3 · 2018: 15 · 2017: 11 · 2016: 9 · 2015: 4 · 2014: 10 · 2013: 7
FWCI: 3.44
Type: journal article
Language: en
Open access: green
www.ncbi.nlm.nih.gov
Licence: www.springer.com/tdm (tdm)
Locations: Journal of Autism and Developmental Disorders (publishedVersion)
PubMed (publishedVersion)
Europe PMC (PubMed Central) (acceptedVersion)
PubMed Central (acceptedVersion)
Funders: Simons Foundation
National Institute of Mental Health (R01MH087554)
Eunice Kennedy Shriver National Institute of Child Health and Human Development (P01HD003008)
Topics: Life Sciences › Neuroscience › Cognitive Neuroscience › Autism Spectrum Disorder Research
Health Sciences › Medicine › Psychiatry and Mental health › Child Nutrition and Feeding Issues
Social Sciences › Psychology › Developmental and Educational Psychology › Child and Animal Learning Development
Keywords: autism spectrum disorder, Autism Diagnostic Observation Schedule, early screening, decision tree induction
MeSH terms: Algorithms, Child Development, Child Development Disorders, Pervasive, Child, Preschool, Female, Humans, Infant, Male, Predictive Value of Tests, Prospective Studies, Risk Factors

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Predicting Developmental Status from 12 to 24 Months in Infants at Risk for Autism Spectrum Disorder: A Preliminary Report

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