Reduced Sensory Habituation in Autism and Its Correlation with Behavioral Measures
Open accessAbstract
Autism is strongly associated with sensory processing difficulties. We investigate sensory habituation, given its relevance for understanding important phenotypic traits like hyper- and hypo-sensitivities. We collected electroencephalography data from 22 neuro-typical(NT) and 13 autistic(ASD) children during the presentation of visual and auditory sequences of repeated stimuli. Our data show that the ASD children have significantly reduced habituation relative to the NT children for both auditory and visual stimuli. These results point to impaired habituation as a modality-general phenomenon in ASD. Additionally, the rates of habituation are correlated with several clinical scores associated with competence along diverse phenotypic dimensions. These data suggest that the sensory difficulties in autism are likely to be associated with reduced habituation and are related to clinical symptomology.
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For neurotypical subjects, P1 is stronger in the initial section of stimuli sequence, showing a gradual reduction in ERP amplitude over time (habituation).
“For neurotypical subjects, P1 is stronger in the initial section of stimuli sequence, showing a gradual reduction in ERP amplitude over time (habituation) (Jamal et al. 2020).”
From Autism Spectrum Disorder and auditory sensory alterations: a systematic review on the integrity of cognitive and neuronal functions related to auditory processing (2023) · cites this paper as Jamal et al. 2020
Pronounced habituation slopes have been observed for neurotypical subjects, with greatest difference at channel Fp1 and in the frontal and fronto-central electrodes.
“Pronounced habituation slopes have been observed for neurotypical subjects, with greatest difference at channel Fp1 and in the frontal and fronto-central electrodes (Jamal et al. 2020).”
From Autism Spectrum Disorder and auditory sensory alterations: a systematic review on the integrity of cognitive and neuronal functions related to auditory processing (2023) · cites this paper as Jamal et al. 2020
The ASD group shows absence of reduction between the first and last ERP, or even a positive slope toward the end of the experiment (reduced habituation).
“On the other hand, the ASD group shows absence of reduction between the first and last ERP, or even a positive slope toward the end of the experiment (reduced habituation) (Jamal et al. 2020).”
From Autism Spectrum Disorder and auditory sensory alterations: a systematic review on the integrity of cognitive and neuronal functions related to auditory processing (2023) · cites this paper as Jamal et al. 2020
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Gonçalves, A. M., & Monteiro, P. (2023) · Journal of Neural Transmission · doi:10.1007/s00702-023-02595-9 · Cited by 88 · see citing works
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- Authors
- Jamal, W., Cardinaux, A., Haskins, A. J., Kjelgaard, M., & Sinha, P.
- Affiliations
- Massachusetts Institute of Technology (US)
- Dartmouth College (US)
- MGH Institute of Health Professions (US)
- Corresponding author
- Jamal, Wasifa
- Venue
- Journal of Autism and Developmental Disorders
- Published
- 2020-11-11
- Volume
- 51
- Issue
- 9
- Pages
- 3153-3164
- ISSN
- 0162-3257 (ISSN-L)
- 1573-3432
- OpenAlex
- W3102438495
- Cited by
- 69
- References
- 11
- Citations by year
- 2026: 17 · 2025: 10 · 2024: 14 · 2023: 17 · 2022: 8 · 2021: 3
- FWCI
- 3.74
- Type
- journal article
- Language
- en
- Open access
- green
- hdl.handle.net
- Licence
- Locations
- Journal of Autism and Developmental Disorders (publishedVersion)
- PubMed (publishedVersion)
- DSpace@MIT (Massachusetts Institute of Technology) (submittedVersion, cc-by-nc-sa)
- Funders
- Simons Foundation Autism Research Initiative
- Topics
- Life Sciences › Neuroscience › Cognitive Neuroscience › Autism Spectrum Disorder Research
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Genetics and Neurodevelopmental Disorders
- Health Sciences › Medicine › Psychiatry and Mental health › Child Nutrition and Feeding Issues
- Keywords
- autism spectrum disorder, sensory habituation, sensory processing difficulties, auditory stimuli, visual stimuli, EEG, children, clinical symptom score
- MeSH terms
- Autism Spectrum Disorder, Autistic Disorder, Child, Cognition, Electroencephalography, Habituation, Psychophysiologic, Humans
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