Preliminary evidence suggesting caution in the use of psychiatric self-report measures with adolescents with high-functioning autism spectrum disorders
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This study investigated the utility of self-report measures to screen for psychiatric comorbidities in autism spectrum disorders (ASDs). Thirty-eight 10-17 year olds with an ASD and without mental retardation completed: the Children's Depression Inventory-Short version (CDI-S), Revised Children's Manifest Anxiety Scale (RCMAS), Conners-Wells Adolescent Self-report Scale-Short edition (CASS-S), and Short Leyton Obsessional Inventory-Child Version (SLOI-CV). Their parents were interviewed with the Autism Comorbidity Interview-Present and Lifetime (ACI-PL) to establish psychiatric diagnoses. Sensitivity, specificity, positive and negative predictive values, and reliability coefficients were calculated for each self-report and compared to values from literature. The CDI-S and CASS-S yielded a high number of false negatives, with lower sensitivities and specificities in the sample than the literature. There was a nearly significant difference in total mean RCMAS scores between participants with and without anxiety, though again the means for both groups were below the threshold of concern. The SLOI-CV yielded a high false positive rate. All four instruments had reliability coefficients comparable to literature values. Results must be considered preliminary due to sample size. However, the findings suggest that although self-report instruments may provide useful information in the diagnosis of psychiatric comorbidities in ASD, caution must be exercised in their interpretation.
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Consequently, researchers have often avoided attending to first-person testimony, preferring to privilege reports from parents, teachers or other informants, or laboratory-based observation over considering the perspectives of the person themselves.
“Consequently, researchers have often avoided attending to first‐person testimony, preferring to privilege reports from parents, teachers or other informants, or laboratory‐based observation over considering the perspectives of the person themselves (Jaswal & Akhtar, 2018; Mazefsky, Kao, & Oswald, 2011; McGeer, 2004; Milton, 2012).”
From Annual Research Review: Shifting from ‘normal science’ to neurodiversity in autism science (2022) · cites this paper as Mazefsky, Kao, & Oswald, 2011
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Experimental — accuracy not yet measuredAlexithymia has been well-documented in autism spectrum disorder.
“First, alexithymia, or difficulty identifying, distinguishing, and describing emotions, has been well-documented in ASD.17,18,19”
From Emotion Regulation (2014) · cites this paper as [18]
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- Authors
- Mazefsky, C. A., Kao, J., & Oswald, D. P.
- Affiliations
- University of Pittsburgh (US)
- Virginia Commonwealth University (US)
- Corresponding author
- Mazefsky, C.A.
- Venue
- Research in Autism Spectrum Disorders
- Publisher
- Elsevier BV
- Published
- 2011-01
- Volume
- 5
- Issue
- 1
- Pages
- 164-174
- ISSN
- 1878-0237 (ISSN-L)
- 1750-9467
- PMC
- PMC3762501
- OpenAlex
- W2077644735
- Cited by
- 325
- References
- 41
- Citations by year
- 2026: 10 · 2025: 19 · 2024: 30 · 2023: 11 · 2022: 24 · 2021: 28 · 2020: 30 · 2019: 20 · 2018: 17 · 2017: 26 · 2016: 14 · 2015: 25 · 2014: 23 · 2013: 23 · 2012: 10
- FWCI
- 9.28
- Type
- journal article
- Language
- en
- Open access
- green
- europepmc.org
- Locations
- Research in Autism (publishedVersion)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- Funders
- Organization for Autism Research
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (K23HD060601, L40 HD051318)
- Topics
- Life Sciences › Neuroscience › Cognitive Neuroscience › Autism Spectrum Disorder Research
- Social Sciences › Psychology › Clinical Psychology › Child and Adolescent Psychosocial and Emotional Development
- Health Sciences › Medicine › Psychiatry and Mental health › Child Nutrition and Feeding Issues
- Keywords
- autism spectrum disorder, high-functioning autism, adolescents, psychiatric comorbidity, self-report measures, depression screening, anxiety screening, obsessive-compulsive symptoms, Revised Children's Manifest Anxiety Scale, screening sensitivity and specificity, false positives and false negatives
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