Oral administration of Anabaena-expressed VP28 for both drug and food against white spot syndrome virus in shrimp
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Anabaena-expressed VP28 has been used for oral administration against white spot syndrome virus in shrimp, and transgenic Synechococcus elongatus PCC 7942 has been developed to express a VP28-mOrange fusion protein for traceable oral delivery studies.
“Cyanobacteria have also been investigated for vaccine-related protein delivery, with Anabaena-expressed VP28 used for oral administration against white spot syndrome virus in shrimp, and transgenic Synechococcus elongatus PCC 7942 further developed to express a VP28–mOrange fusion protein for traceable oral delivery studies [189,190].”
From Cyanobacteria as a Photosynthetic Chassis for Metabolic Pathway Engineering with Heterologous Gene Expression (2026) · cites this paper as [190]
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- Authors
- Jia, X.-H., Zhang, C.-L., Shi, D.-J., Zhuang, M.-M., Wang, X., Jia, R., Zhang, Z.-Y., Huang, J., Sun, Y.-H., Qian, W.-Y., Peng, G.-H., & He, P.-M.
- Affiliations
- Shanghai Ocean University (CN)
- Max Planck Institute of Biophysics (DE)
- Yellow Sea Fisheries Research Institute (CN)
- Corresponding author
- Jia, Rui
- Venue
- Journal of Applied Phycology
- Published
- 2015-05-15
- Volume
- 28
- Issue
- 2
- Pages
- 1001-1009
- ISSN
- 0921-8971 (ISSN-L)
- 1573-5176
- OpenAlex
- W2187710323
- Cited by
- 37
- References
- 52
- Citations by year
- 2026: 5 · 2025: 7 · 2024: 5 · 2023: 5 · 2022: 4 · 2021: 3 · 2020: 5 · 2019: 2 · 2018: 1
- FWCI
- 0.16
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- www.springer.com/tdm (tdm)
- Locations
- Journal of Applied Phycology (publishedVersion)
- Institute of Botany, CAS Institutional Repository (submittedVersion)
- MPG.PuRe (Max Planck Society) (submittedVersion)
- Funders
- Ministry of Science and Technology of the People's Republic of China
- Science and Technology Commission of Shanghai Municipality
- Topics
- Life Sciences › Immunology and Microbiology › Immunology › Aquaculture disease management and microbiota
- Life Sciences › Agricultural and Biological Sciences › Aquatic Science › Aquaculture Nutrition and Growth
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Biotechnology › Transgenic Plants and Applications
- Keywords
- white spot syndrome virus, VP28, oral vaccine, Anabaena sp. PCC 7120, transgenic cyanobacteria, Litopenaeus vannamei, post-larval shrimp, heterologous expression, edible vaccines, photosynthesis
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