The role of dopamine oxidation in mitochondrial dysfunction: implications for Parkinson’s disease

Parkin is recruited selectively to impaired mitochondria and promotes their autophagy

Narendra, D., Tanaka, A., Suen, D.-F., & Youle, R. J. (2008) · The Journal of Cell Biology · doi:10.1083/jcb.200809125 · Cited by 4,026 · see citing works

Chronic systemic pesticide exposure reproduces features of Parkinson's disease

Betarbet, R., Sherer, T., Mackenzie, G., Garcia-Osuna, M., Panov, A., & Greenamyre, J. (2000) · Nature Neuroscience · doi:10.1038/81834 · Cited by 3,797 · see citing works

Autoxidation versus Covalent Binding of Quinones as the Mechanism of Toxicity of Dopamine, 6-Hydroxydopamine, and Related Compounds toward C1300 Neuroblastoma Cells in Vitro

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Parkinson's disease: from monogenic forms to genetic susceptibility factors

Lesage, S., & Brice, A. (2009) · Human Molecular Genetics · doi:10.1093/hmg/ddp012 · Cited by 946 · see citing works

A highly reproducible rotenone model of Parkinson's disease

Cannon, J. R., Tapias, V., Na, H. M., Honick, A. S., Drolet, R. E., & Greenamyre, J. T. (2009) · Neurobiology of Disease · doi:10.1016/j.nbd.2009.01.016 · Cited by 802 · see citing works

Dopamine covalently modifies and functionally inactivates parkin

LaVoie, M. J., Ostaszewski, B. L., Weihofen, A., Schlossmacher, M. G., & Selkoe, D. J. (2005) · Nature Medicine · doi:10.1038/nm1314 · Cited by 722 · see citing works

Dopamine Oxidation Alters Mitochondrial Respiration and Induces Permeability Transition in Brain Mitochondria

Berman, S. B., & Hastings, T. G. (1999) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.1999.0731127.x · Cited by 664 · see citing works

Dopamine-modified α-synuclein blocks chaperone-mediated autophagy

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Multiple hit hypotheses for dopamine neuron loss in Parkinson's disease

Sulzer, D. (2007) · Trends in Neurosciences · doi:10.1016/j.tins.2007.03.009 · Cited by 583 · see citing works

Role of oxidation in the neurotoxic effects of intrastriatal dopamine injections.

Hastings, T. G., Lewis, D. A., & Zigmond, M. J. (1996) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.93.5.1956 · Cited by 547 · see citing works

The Mitochondrial Inner Membrane Protein Mitofilin Controls Cristae Morphology

John, G. B., Shang, Y., Li, L., Renken, C. W., Mannella, C. A., Selker, J. M. L., Rangell, L. K., Bennett, M. J., & Zha, J. (2005) · Molecular Biology of the Cell · doi:10.1091/mbc.e04-08-0697 · Cited by 459 · see citing works

Parkinson's--Divergent Causes, Convergent Mechanisms

Greenamyre, J. T., & Hastings, T. G. (2004) · Science · doi:10.1126/science.1098966 · Cited by 453 · see citing works

Reduced Vesicular Storage of Dopamine Causes Progressive Nigrostriatal Neurodegeneration

Caudle, W. M., Richardson, J. R., Wang, M. Z., Taylor, T. N., Guillot, T. S., McCormack, A. L., Colebrooke, R. E., Monte, D. A. D., Emson, P. C., & Miller, G. W. (2007) · Journal of Neuroscience · doi:10.1523/jneurosci.0319-07.2007 · Cited by 389 · see citing works

Structural and functional link between the mitochondrial network and the endoplasmic reticulum

Giorgi, C., Stefani, D. D., Bononi, A., Rizzuto, R., & Pinton, P. (2009) · The International Journal of Biochemistry & Cell Biology · doi:10.1016/j.biocel.2009.04.010 · Cited by 375 · see citing works

Conjugates of Catecholamines with Cysteine and GSH in Parkinson's Disease: Possible Mechanisms of Formation Involving Reactive Oxygen Species

Spencer, J. P. E., Jenner, P., Daniel, S. E., Lees, A. J., Marsden, D. C., & Halliwell, B. (1998) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.1998.71052112.x · Cited by 373 · see citing works

Enzymatic Oxidation of Dopamine: The Role of Prostaglandin H Synthase

Hastings, T. G. (1995) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.1995.64020919.x · Cited by 359 · see citing works

Intersecting pathways to neurodegeneration in Parkinson's disease: Effects of the pesticide rotenone on DJ-1, α-synuclein, and the ubiquitin–proteasome system

Betarbet, R. S., Canet-Aviles, R., Sherer, T., Mastroberardino, P. G., McLendon, C., Kim, J.-H., Lund, S. A., Na, H. M., Taylor, G., Bence, N., et al. (2006) · Neurobiology of Disease · doi:10.1016/j.nbd.2005.12.003 · Cited by 342 · see citing works

Impaired mitochondrial dynamics and function in the pathogenesis of Parkinson's disease

Büeler, H. (2009) · Experimental Neurology · doi:10.1016/j.expneurol.2009.03.006 · Cited by 326 · see citing works

Glutathione—a review on its role and significance in Parkinson's disease

Martin, H. L., & Teismann, P. (2009) · The FASEB Journal · doi:10.1096/fj.08-125443 · Cited by 314 · see citing works

Dopamine neurons release transmitter via a flickering fusion pore

Staal, R. G. W., Mosharov, E. V., & Sulzer, D. L. (2004) · Nature Neuroscience · doi:10.1038/nn1205 · Cited by 308 · see citing works

Neuromelanin of the substantia nigra: a neuronal black hole with protective and toxic characteristics

Zecca, L., Zucca, F. A., Wilms, H., & Sulzer, D. L. (2003) · Trends in Neurosciences · doi:10.1016/j.tins.2003.08.009 · Cited by 265 · see citing works

Mitochondrial dysfunction in the limelight of Parkinson's disease pathogenesis

Banerjee, R., Starkov, A. A., Beal, M. F., & Thomas, B. (2008) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/j.bbadis.2008.11.007 · Cited by 256 · see citing works

Unregulated Cytosolic Dopamine Causes Neurodegeneration Associated with Oxidative Stress in Mice

Chen, L., Ding, Y., Cagniard, B., Laar, A. D. V., Mortimer, A. D., Chi, W., Hastings, T. G., Kang, U. J., & Zhuang, X. (2008) · Journal of Neuroscience · doi:10.1523/jneurosci.3602-07.2008 · Cited by 238 · see citing works

The mitochondrial inner membrane protein Mitofilin exists as a complex with SAM50, metaxins 1 and 2, coiled‐coil‐helix coiled‐coil‐helix domain‐containing protein 3 and 6 and DnaJC11

Xie, J., Marusich, M. F., Souda, P., Whitelegge, J. P., & Capaldi, R. (2007) · FEBS Letters · doi:10.1016/j.febslet.2007.06.052 · Cited by 223 · see citing works

Accelerated Oligomerization by Parkinson's Disease Linked α‐Synuclein Mutants

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Interactions Among α-Synuclein, Dopamine, and Biomembranes: Some Clues for Understanding Neurodegeneration in Parkinson's Disease

Rochet, J., Outeiro, T. F., Conway, K. A., Ding, T. T., Volles, M. J., Lashuel, H. A., Bieganski, R. M., Lindquist, S. L., & Lansbury, P. T. (2004) · Journal of Molecular Neuroscience · doi:10.1385/jmn:23:1-2:023 · Cited by 191 · see citing works

Nitric oxide induces coupling of mitochondrial signalling with the endoplasmic reticulum stress response

Xu, W., Liu, L., Charles, I. G., & Moncada, S. (2004) · Nature Cell Biology · doi:10.1038/ncb1188 · Cited by 182 · see citing works

Identification of Catechol‐Protein Conjugates in Neostriatal Slices Incubated with [3H]Dopamine: Impact of Ascorbic Acid and Glutathione

Hastings, T. G., & Zigmond, M. J. (1994) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.1994.63031126.x · Cited by 168 · see citing works

Mendelian forms of Parkinson's disease

Gasser, T. (2009) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/j.bbadis.2008.12.007 · Cited by 161 · see citing works

Proteomic identification of dopamine-conjugated proteins from isolated rat brain mitochondria and SH-SY5Y cells

Laar, V. S. V., Mishizen-Eberz, A. J., Cascio, M., & Hastings, T. G. (2009) · Neurobiology of Disease · doi:10.1016/j.nbd.2009.03.004 · Cited by 151 · see citing works

Oxidative stress‐triggered unfolded protein response is upstream of intrinsic cell death evoked by parkinsonian mimetics

Holtz, W. A., Turetzky, J. M., Jong, Y.-J. I., & O’Malley, K. L. (2006) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2006.04025.x · Cited by 126 · see citing works

Sequence requirements for formation of conformational variants of tau similar to those found in Alzheimer's disease

Jicha, G. A., Berenfeld, B., & Davies, P. (1999) · Journal of Neuroscience Research · doi:10.1002/(sici)1097-4547(19990315)55:6 · Cited by 123 · see citing works

Altered vesicular dopamine storage in Parkinson's disease: a premature demise

Caudle, W. M., Colebrooke, R. E., Emson, P. C., & Miller, G. W. (2008) · Trends in Neurosciences · doi:10.1016/j.tins.2008.02.010 · Cited by 119 · see citing works

Role of oxidative changes in the degeneration of dopamine terminals after injection of neurotoxic levels of dopamine

Rabinovic, A. D., Lewis, D. A., & Hastings, T. G. (2000) · Neuroscience · doi:10.1016/s0306-4522(00)00293-1 · Cited by 117 · see citing works

Quantitative Biochemical and Ultrastructural Comparison of Mitochondrial Permeability Transition in Isolated Brain and Liver Mitochondria: Evidence for Reduced Sensitivity of Brain Mitochondria

Berman, S. B., Watkins, S. C., & Hastings, T. G. (2000) · Experimental Neurology · doi:10.1006/exnr.2000.7438 · Cited by 115 · see citing works

Differential effects of PINK1 nonsense and missense mutations on mitochondrial function and morphology

Grünewald, A., Gegg, M. E., Taanman, J., King, R. H. M., Kock, N., Klein, C., & Schapira, A. H. V. (2009) · Experimental Neurology · doi:10.1016/j.expneurol.2009.05.027 · Cited by 110 · see citing works

Proteomic analysis of rat brain mitochondria following exposure to dopamine quinone: Implications for Parkinson disease

Laar, V. S. V., Dukes, A. A., Cascio, M., & Hastings, T. G. (2007) · Neurobiology of Disease · doi:10.1016/j.nbd.2007.11.007 · Cited by 109 · see citing works

Changes in endoplasmic reticulum stress proteins and aldolase A in cells exposed to dopamine

Dukes, A. A., Laar, V. S. V., Cascio, M., & Hastings, T. G. (2008) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2008.05392.x · Cited by 70 · see citing works

Reactive Oxygen Species, Toxicity, Oxidative Stress, and Antioxidants: Chronic Diseases and Aging

Jomova, K., Raptova, R., Alomar, S. Y., Alwasel, S. H., Nepovimova, E., Kuca, K., & Valko, M. (2023) · Archives of Toxicology · doi:10.1007/s00204-023-03562-9 · Cited by 2,638 · see citing works

The Role of Oxidative Stress in Parkinson's Disease

Dias, V., Junn, E., & Mouradian, M. M. (2013) · Journal of Parkinson’s Disease · doi:10.3233/jpd-130230 · Cited by 1,845 · see citing works

Insulin resistance in brain alters dopamine turnover and causes behavioral disorders

Kleinridders, A., Cai, W., Cappellucci, L., Ghazarian, A., Collins, W. R., Vienberg, S. G., Pothos, E. N., & Kahn, C. R. (2015) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1500877112 · Cited by 486 · see citing works

Clinical trials of N-acetylcysteine in psychiatry and neurology: A systematic review

Deepmala, Slattery, J., Kumar, N., Delhey, L., Berk, M., Dean, O., Spielholz, C., & Frye, R. (2015) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2015.04.015 · Cited by 463 · see citing works

The promise of N-acetylcysteine in neuropsychiatry

Berk, M., Malhi, G. S., Gray, L. J., & Dean, O. M. (2013) · Trends in Pharmacological Sciences · doi:10.1016/j.tips.2013.01.001 · Cited by 434 · see citing works

Associations of ozone and PM2. 5 concentrations with Parkinson's disease among participants in the agricultural health study

Kirrane, E. F., Bowman, C., Davis, J. A., Hoppin, J. A., Blair, A., Chen, H., Patel, M. M., Sandler, D. P., Tanner, C. M., Vinikoor-Imler, L., et al. (2015) · Journal of Occupational & Environmental Medicine · doi:10.1097/jom.0000000000000451 · Cited by 100 · see citing works

Metallobiology of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine neurotoxicity

Hare, D. J., Adlard, P. A., Doble, P. A., & Finkelstein, D. I. (2013) · Metallomics · doi:10.1039/c2mt20164j · Cited by 78 · see citing works

Morphological parameters of the heterogeneity of the substantia nigra in elderly men and women

Николаевич, С. В., Худоерков, Р. М., Воронков, Д. Н., et al. (2015) · Russian Journal of Archive of Pathology · doi:10.17116/patol201577451-54 · Cited by 3 · see citing works

Quantitative research on FA value of substantia nigra pars compacta in early Parkinson′s disease

Yan-shen, C. (2014) · Radiologic Practice

Detecting parkinsonian degeneration in lateroventral tier of substantia nigra pars compacta with MRI

Langley, J. A., Huddleston, D. E., & Hu, X. P. (2020) · Elsevier eBooks · doi:10.1016/b978-0-12-815950-7.00020-5 · Cited by 2 · see citing works

Age and Parkinson’s Disease-Related Neuronal Death in the Substantia Nigra Pars Compacta

Eriksen, N., Stark, A. K., & Pakkenberg, B. (2009) · Springer eBooks · doi:10.1007/978-3-211-92660-4_16 · Cited by 37 · see citing works

Threedimensional reconstruction of substantia nigra pars compacta of human brain

Воронков, Д. Н., Николаевич, С. В., & Худоерков, Р. М. (2018) · I P Pavlov Russian Medical Biological Herald · doi:10.23888/pavlovj20182175-183