An overview of apoptosis assays detecting DNA fragmentation

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A simple technique for quantitation of low levels of DNA damage in individual cells

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Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation.

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A novel assay for apoptosis Flow cytometric detection of phosphatidylserine expression on early apoptotic cells using fluorescein labelled Annexin V

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Glucocorticoid-induced thymocyte apoptosis is associated with endogenous endonuclease activation

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miR-15 and miR-16 induce apoptosis by targeting BCL2

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A caspase-activated DNase that degrades DNA during apoptosis, and its inhibitor ICAD

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Neurogenesis in the dentate gyrus of the adult rat: age-related decrease of neuronal progenitor proliferation

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The Comet Assay for DNA Damage and Repair: Principles, Applications, and Limitations

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Apoptosis in cancer: from pathogenesis to treatment

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Caspase Functions in Cell Death and DiseasePreprint

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Caspase-3 Is Required for DNA Fragmentation and Morphological Changes Associated with Apoptosis

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The comet assay: a method to measure DNA damage in individual cells

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DFF, a Heterodimeric Protein That Functions Downstream of Caspase-3 to Trigger DNA Fragmentation during Apoptosis

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Microelectrophoretic study of radiation-induced DNA damages in individual mammalian cells

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The comet assay: a comprehensive review

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Apoptosis in neurodegenerative disorders

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Morphologic and biochemical hallmarks of apoptosis

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In situ detection of fragmented dna (tunel assay) fails to discriminate among apoptosis, necrosis, and autolytic cell death: A cautionary note

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Inhibition of VEGF receptors causes lung cell apoptosis and emphysema

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Caspases in apoptosis and beyond

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Apoptosis is induced by beta-amyloid in cultured central nervous system neurons.

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Apoptotic DNA Fragmentation

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The morphology of apoptosis

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The role of phosphatidylserine in recognition of apoptotic cells by phagocytes

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A cross-platform public domain PC image-analysis program for the comet assay

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The kinetics of repair of oxidative DNA damage (strand breaks and oxidised pyrimidines) in human cells

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Key morphological features of apoptosis may occur in the absence of internucleosomal DNA fragmentation

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A Selective Procedure for DNA Extraction from Apoptotic Cells Applicable for Gel Electrophoresis and Flow Cytometry

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A rapid and simple method for the isolation of apoptotic DNA fragments

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In situ end‐labelling detects DNA strand breaks in apoptosis and other physiological and pathological states

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Detection of Apoptosis by TUNEL Assay

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Analysis of cycloheximide-induced apoptosis in human leukocytes: Fluorescence microscopy using annexin V/propidium iodide versus acridin orange/ethidium bromide

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Degradation of chromosomal DNA during apoptosis

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Evidence that ultrafine titanium dioxide induces micronuclei and apoptosis in Syrian hamster embryo fibroblasts.

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Comparison of Chromatin Assays for DNA Fragmentation Evaluation in Human Sperm

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Caspase-3 Activation is a Critical Determinant of Genotoxic Stress-Induced Apoptosis

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The Comet Assay (Single-Cell Gel Test): A Sensitive Genotoxicity Test for the Detection of DNA Damage and Repair

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The protein phosphatase inhibitor okadaic acid induces morphological changes typical of apoptosis in mammalian cells

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Significance of Myocytes With Positive DNA In Situ Nick End-Labeling (TUNEL) in Hearts With Dilated Cardiomyopathy

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Discontinuous fragmentation of nuclear DNA during apoptosis revealed by discrete “sub‐G 1 ” peaks on DNA content histograms

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EdU, a new thymidine analogue for labelling proliferating cells in the nervous system

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Detection of S-phase Cell Cycle Progression using 5-ethynyl-2′-deoxyuridine Incorporation with Click Chemistry, an Alternative to using 5-bromo-2′-deoxyuridine Antibodies

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Detection of DNA fragmentation in apoptosis: application of in situ nick translation to cell culture systems and tissue sections.

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Radiation-Induced Apoptosis Measured in TK6 Human B Lymphoblast Cells Using the Comet Assay

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DNA labeling in living cells

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Imatinib (STI571)-Mediated Changes in Glucose Metabolism in Human Leukemia BCR-ABL-Positive Cells

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Caspase-3 Activation Is a Critical Determinant of Genotoxic Stress-Induced Apoptosis

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DNA STRAND BREAKS OCCURRING DURING APOPTOSIS - THEIR EARLY INSITU DETECTION BY THE TERMINAL DEOXYNUCLEOTIDYL TRANSFERASE AND NICK TRANSLATION ASSAYS AND PREVENTION BY SERINE PROTEASE INHIBITORS

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Analysis of apoptosis by cytometry using TUNEL assay

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The BCL-2 family of proteins and mitochondrial outer membrane permeabilisation

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Evaluation of DNA damage using single-cell gel electrophoresis (Comet Assay)

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Labelling DNA strand breaks with BrdUTP. Detection of apoptosis and cell proliferation

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Screening and Detection of Apoptosis

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Measuring apoptosis by microscopy and flow cytometry

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A novel method to determine specificity and sensitivity of the TUNEL reaction in the quantitation of apoptosis

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Cleavage Preferences of the Apoptotic Endonuclease DFF40 (Caspase-activated DNase or Nuclease) on Naked DNA and Chromatin Substrates

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Identification of necrotic cell death by the TUNEL assay in the hypoxic-ischemic neonatal rat brain

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Comparison of Comet Assay, Electron Microscopy, and Flow Cytometry for Detection of Apoptosis

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Prolonged cell survival enhances peritoneal dissemination of gastric cancer cells

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Discrimination between primary necrosis and apoptosis by necrostatin-1 in Annexin V-positive/propidium iodide-negative cells

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Apoptosis induced by mild hyperthermia in human and murine tumour cell lines: A study using electron microscopy and DNA gel electrophoresis

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Comet assay and early apoptosis

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An update to DNA ladder assay for apoptosis detection

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Endurance exercise results in DNA damage as detected by the comet assay

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Kaempferol sensitizes colon cancer cells to TRAIL-induced apoptosis

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Binding of 4',6-diamidino-2-phenylindole (DAPI) to AT regions of DNA: Evidence for an allosteric conformational change

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DNA in chromatin of irradiated lymphoid tissues degrades in vivo into regular fragments

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Apoptosis and necrosis of human breast cancer cells by an aqueous extract of garden cress (Lepidium sativum) seeds

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Melatonin sensitizes human cervical cancer H e L a cells to cisplatin‐induced cytotoxicity and apoptosis: effects on oxidative stress and DNA fragmentation

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Se-Methylselenocysteine induces apoptosis through caspase activation in HL-60 cells

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The DFF40/CAD endonuclease and its role in apoptosis.

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Atomic Force Microscopy Study of Early Morphological Changes during Apoptosis

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ESTIMATION OF DNA STRAND BREAKS IN SINGLE MAMMALIAN CELLS

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Analysis of radiation‐induced apoptosis in human lymphocytes: Flow cytometry using Annexin V and propidium iodide versus the neutral comet assay

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Silver-Stained Comet Assay for Detection of Apoptosis

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An improved non-enzymatic “DNA ladder assay” for more sensitive and early detection of apoptosis

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Concentration‐dependent induction of reactive oxygen species, cell cycle arrest and apoptosis in human liver cells after nickel nanoparticles exposure

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Cellular responses to etoposide: cell death despite cell cycle arrest and repair of DNA damage

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Apoptosis in mouse primordial germ cells: a study by transmission and scanning electron microscope

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On the search for an intelligible comet assay descriptor

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Analysis of Cell Death by Electron Microscopy

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D-Pinitol Promotes Apoptosis in MCF-7 Cells via Induction of p53 and Bax and Inhibition of Bcl-2 and NF-κB

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Inter‐ and intra‐laboratory standardization of TUNEL assay for assessment of sperm DNA fragmentation

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Elongation factor-2 kinase acts downstream of p38 MAPK to regulate proliferation, apoptosis and autophagy in human lung fibroblasts

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Erratum: correction: A caspase-activated DNase that degrades DNA during apoptosis and its inhibitor ICAD

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Two-Tailed Comet Assay (2T-Comet): Simultaneous Detection of DNA Single and Double Strand Breaks

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Ganoderma lucidum total triterpenes induce apoptosis in MCF-7 cells and attenuate DMBA induced mammary and skin carcinomas in experimental animals

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