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Structure, substrate specificity, and catalytic mechanism of human D-2-HGDH and insights into pathogenicity of disease-associated mutations

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NADP+-dependent IDH1R132 mutation and its relevance for glioma patient survival

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Isocitrate dehydrogenase 1/2 mutational analyses and 2‐hydroxyglutarate measurements in Wilms tumors

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Differential Activity of NADPH-Producing Dehydrogenases Renders Rodents Unsuitable Models to Study IDH1 R132 Mutation Effects in Human Glioblastoma

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Pheochromocytomas and Paragangliomas: Bypassing Cellular Respiration

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Genetic alterations in chondrosarcomas – keys to targeted therapies?

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Wilms Tumor in a Child with L-2-hydroxyglutaric Aciduria

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Plants Possess a Cyclic Mitochondrial Metabolic Pathway similar to the Mammalian Metabolic Repair Mechanism Involving Malate Dehydrogenase and l-2-Hydroxyglutarate Dehydrogenase

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In Vivo Modeling of Malignant Glioma

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Experimental Evidence that In Vivo Intracerebral Administration of L-2-Hydroxyglutaric Acid to Neonatal Rats Provokes Disruption of Redox Status and Histopathological Abnormalities in the Brain

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Characterization of cancer-associated IDH2 mutations that differ in tumorigenicity, chemosensitivity and 2-hydroxyglutarate production

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The role of mutation of metabolism-related genes in genomic hypermethylation

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IDH1 mutant structures reveal a mechanism of dominant inhibition

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Isocitrate dehydrogenase mutations may be a protective mechanism in glioma patients

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IDH2 mutation in gliomas including novel mutation

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Prognostic Markers in Gliomas

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Molecular Pathogenesis of Malignant Glial Tumors

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IDH1 mutation, a genetic alteration associated with adult gliomatosis cerebri

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Expression of R132H Mutational IDH1 in Human U87 Glioblastoma Cells Affects the SREBP1a Pathway and Induces Cellular Proliferation

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Glioma-derived mutations in isocitrate dehydrogenase 2 beneficial to traditional chemotherapy

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Targeting Metabolic Reprogramming of T-Cells for Enhanced Anti-Tumor Response

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Molecular Pathogenesis and Emerging Treatment for Glioblastoma

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Metabolomics in renal cell carcinoma: From biomarker identification to pathomechanism insights

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Metabolism of glioblastoma: a review of metabolic adaptations and metabolic therapeutic interventions

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A lymphoblast model for IDH2 gain-of-function activity in d-2-hydroxyglutaric aciduria type II: Novel avenues for biochemical and therapeutic studies

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Another small molecule in the oncometabolite mix: L-2-Hydroxyglutarate in kidney cancer

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Structure and biochemical characterization of l-2-hydroxyglutarate dehydrogenase and its role in the pathogenesis of l-2-hydroxyglutaric aciduria

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Degradation of D-2-hydroxyglutarate in the presence of isocitrate dehydrogenase mutations

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L-2-hydroxyglutaric aciduria and brain malignant tumors: A predisposing condition?

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L -2-Hydroxyglutaric Aciduria and Brain Tumors in Children with Mutations in the L2HGDH Gene: Neuroimaging Findings

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Successive distinct high‐grade gliomas in L‐2‐hydroxyglutaric aciduria

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L-2 Hydroxyglutaric Aciduria and Anaplastic Oligodendroglioma: a Rare Association

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Cerebral neoplasm in L-2-hydroxyglutaric aciduria: two different presentations

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