The DOI matches its Crossref record; 6 of the 6 references it cites were found in a registry or an index.
Apigenin: A Promising Molecule for Cancer Prevention
Open accessAbstract
ABSTRACTApigenin, a naturally occurring plant flavone, abundantly present in common fruits and vegetables, is recognized as a bioactive flavonoid shown to possess anti-inflammatory, antioxidant and anticancer properties. Epidemiologic studies suggest that a diet rich in flavones is related to a decreased risk of certain cancers, particularly cancers of the breast, digestive tract, skin, prostate and certain hematological malignancies. It has been suggested that apigenin may be protective in other diseases that are affected by oxidative process, such as cardiovascular and neurological disorders, although more research needs to be conducted in this regard. Human clinical trials examining the effect of supplementation of apigenin on disease prevention have not been conducted, although there is considerable potential for apigenin to be developed as a cancer chemopreventive agent.
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Cites
Cancer chemoprevention with dietary phytochemicals
Surh, Y.-J. (2003) · Nature reviews. Cancer · doi:10.1038/nrc1189 · Cited by 2,955
Flavonoids: antioxidants or signalling molecules?
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I NHIBITION OF C ARCINOGENESIS BY D IETARY P OLYPHENOLIC C OMPOUNDS
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PKC-mediated survival signaling in breast carcinoma cells: A role for MEK1-AP1 signaling
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Cited by
The Therapeutic Potential of Apigenin
Salehi, B., Venditti, A., Sharifi-Rad, M., Kręgiel, D., Sharifi-Rad, J., Durazzo, A., Lucarini, M., Santini, A., Souto, E. B., Novellino, E., et al. (2019) · International Journal of Molecular Sciences · doi:10.3390/ijms20061305 · Cited by 1,238
Apigenin: A dietary flavonoid with diverse anticancer properties
Madunić, J., Madunić, I. V., Gajski, G., Popić, J., & Garaj-Vrhovac, V. (2018) · Cancer Letters · doi:10.1016/j.canlet.2017.10.041 · Cited by 357
Hasan, N., Nadaf, A., Imran, M., Jiba, U., Sheikh, A., Almalki, W. H., Almujri, S. S., Mohammed, Y. H., Kesharwani, P., & Ahmad, F. J. (2023) · Molecular Cancer · doi:10.1186/s12943-023-01854-3 · Cited by 322
Review of Natural Compounds for Potential Skin Cancer Treatment
Chinembiri, T., Du Plessis, L., Gerber, M., Hamman, J., & Du Plessis, J. (2014) · Molecules · doi:10.3390/molecules190811679 · Cited by 270
Xu, L., Zhang, Y., Tian, K., Chen, X., Zhang, R., Mu, X., Wu, Y., Wang, D., Wang, S., Liu, F., et al. (2018) · Journal of Experimental & Clinical Cancer Research · doi:10.1186/s13046-018-0929-6 · Cited by 177
Metadata
- Authors
- Shukla, S., & Gupta, S.
- Venue
- Pharmaceutical Research
- Published
- 2010-03-20
- Volume
- 27
- Issue
- 6
- Pages
- 962-978
- ISSN
- 0724-8741 (ISSN-L)
- 1573-904X
- OpenAlex
- W2074951329
- Cited by
- 820
- References
- 6
- FWCI
- 19.47
- Type
- journal article
- Language
- en
- Open access
- green
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
