Polymeric Micelles of PEG-PLA Copolymer as a Carrier for Salinomycin Against Gemcitabine-Resistant Pancreatic Cancer

Cancer statistics, 2012

Siegel, R., Naishadham, D., & Jemal, A. (2012) · CA: A Cancer Journal for Clinicians · doi:10.3322/caac.20138 · Cited by 10,679 · see citing works

Relative expression software tool (REST(C)) for group-wise comparison and statistical analysis of relative expression results in real-time PCR

Pfaffl, M. W. (2002) · Nucleic Acids Research · doi:10.1093/nar/30.9.e36 · Cited by 7,377 · see citing works

A novel assay for apoptosis Flow cytometric detection of phosphatidylserine expression on early apoptotic cells using fluorescein labelled Annexin V

Vermes, I., Haanen, C., Steffens-Nakken, H. M., & Reutellingsperger, C. (1995) · Journal of Immunological Methods · doi:10.1016/0022-1759(95)00072-i · Cited by 5,437 · see citing works

The transcription factor Snail is a repressor of E-cadherin gene expression in epithelial tumour cells

Batlle, E., Sancho, E., Francı́, C., Dominguez-Sola, D., Monfar, M., Baulida, J., & de Herreros, A. G. (2000) · Nature Cell Biology · doi:10.1038/35000034 · Cited by 2,671 · see citing works

EMT, cancer stem cells and drug resistance: an emerging axis of evil in the war on cancer

Singh, A., & Settleman, J. (2010) · Oncogene · doi:10.1038/onc.2010.215 · Cited by 2,545 · see citing works

Identification of Selective Inhibitors of Cancer Stem Cells by High-Throughput Screening

Gupta, P. B., Önder, T. T., Jiang, G., Tao, K. X., Kuperwasser, C., Weinberg, R. A., & Lander, E. S. (2009) · Cell · doi:10.1016/j.cell.2009.06.034 · Cited by 2,386 · see citing works

Micellar Nanocarriers: Pharmaceutical Perspectives

Torchilin, V. P. (2006) · Pharmaceutical Research · doi:10.1007/s11095-006-9132-0 · Cited by 1,910 · see citing works

The two-handed E box binding zinc finger protein SIP1 downregulates E-cadherin and induces invasion.

Comijn, J., Berx, G., Vermassen, P., Verschueren, K., van Grunsven, L. V., Bruyneel, E., Mareel, M., Huylebroeck, D., & van Roy, F. (2001) · Molecules and Cells · doi:10.1016/s1097-2765(01)00260-x · Cited by 1,464 · see citing works

Heterogeneity in Cancer: Cancer Stem Cells versus Clonal Evolution

Shackleton, M. J., Quintana, E., Fearon, E. R., & Morrison, S. J. (2009) · Cell · doi:10.1016/j.cell.2009.08.017 · Cited by 1,152 · see citing works

The transcription factor Slug represses E-cadherin expression and induces epithelial to mesenchymal transitions: a comparison with Snail and E47 repressors

Bolós, V., Peinado, H., Pérez‐Moreno, M., Fraga, M. F., Esteller, M., & Cano, A. (2002) · Journal of Cell Science · doi:10.1242/jcs.00224 · Cited by 1,100 · see citing works

Epithelial to Mesenchymal Transition Contributes to Drug Resistance in Pancreatic Cancer

Arumugam, T., Ramachandran, V., Fournier, K. F., Wang, H., Marquis, L., Abbruzzese, J. L., Gallick, G. E., Logsdon, C. D., McConkey, D. J., & Choi, W. (2009) · Cancer Research · doi:10.1158/0008-5472.can-08-2819 · Cited by 866 · see citing works

Enhanced Permeability and Retention (EPR) Effect for Anticancer Nanomedicine Drug Targeting

Greish, K. (2010) · Methods in Molecular Biology · doi:10.1007/978-1-60761-609-2_3 · Cited by 841 · see citing works

DeltaEF1 is a transcriptional repressor of E-cadherin and regulates epithelial plasticity in breast cancer cells

Eger, A., Aigner, K., Sonderegger, S., Dampier, B., Oehler, S., Schreiber, M., Berx, G., Cano, A., Beug, H., & Foisner, R. (2005) · Oncogene · doi:10.1038/sj.onc.1208429 · Cited by 808 · see citing works

Advanced pancreatic carcinoma: current treatment and future challenges

Stathis, A., & Moore, M. J. (2010) · Nature Reviews Clinical Oncology · doi:10.1038/nrclinonc.2009.236 · Cited by 791 · see citing works

Novel functions of vimentin in cell adhesion, migration, and signaling

Ivaska, J., Pallari, H., Nevo, J., & Eriksson, J. (2007) · Experimental Cell Research · doi:10.1016/j.yexcr.2007.03.040 · Cited by 786 · see citing works

In vivo evaluation of polymeric micellar paclitaxel formulation: toxicity and efficacy

Kim, S. C., Kim, D. W., Shim, Y. H., Bang, J. S., Oh, H. S., Kim, S. W., & Seo, M. H. (2001) · Journal of Controlled Release · doi:10.1016/s0168-3659(01)00275-9 · Cited by 734 · see citing works

Multicenter phase II trial of Genexol-PM, a Cremophor-free, polymeric micelle formulation of paclitaxel, in patients with metastatic breast cancer

Lee, K. S., Chung, H. C., Im, S. A., Park, Y. H., Kim, C. S., Kim, S.-B., Rha, S. Y., Lee, M. Y., & Ro, J. (2008) · Breast Cancer Research and Treatment · doi:10.1007/s10549-007-9591-y · Cited by 541 · see citing works

Genetic programs of epithelial cell plasticity directed by transforming growth factor-β

Zavadil, J., Bitzer, M., Liang, D., Yang, Y.-C., Massimi, A. B., Kneitz, S., Piek, E., & Böttinger, E. P. (2001) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.111614398 · Cited by 534 · see citing works

Triggered destabilisation of polymeric micelles and vesicles by changing polymers polarity: An attractive tool for drug delivery

Rijcken, C. J. F., Soga, O., Hennink, W. E., & van Nostrum, C. F. (2007) · Journal of Controlled Release · doi:10.1016/j.jconrel.2007.03.023 · Cited by 487 · see citing works

Impaired wound healing in embryonic and adult mice lacking vimentin

Eckes, B., Colucci‐Guyon, E., Smola, H., Nodder, S., Babinet, C., Krieg, T. M., & Martin, P. B. (2000) · Journal of Cell Science · doi:10.1242/jcs.113.13.2455 · Cited by 397 · see citing works

Salinomycin as a Drug for Targeting Human Cancer Stem Cells

Naujokat, C., & Steinhart, R. (2012) · BioMed Research International · doi:10.1155/2012/950658 · Cited by 355 · see citing works

The eradication of breast cancer and cancer stem cells using octreotide modified paclitaxel active targeting micelles and salinomycin passive targeting micelles

Zhang, Y., Zhang, H., Wang, X., Wang, J., Zhang, X., & Zhang, Q. (2011) · Biomaterials · doi:10.1016/j.biomaterials.2011.09.072 · Cited by 193 · see citing works

Tumor stroma as targets for cancer therapy

Zhang, J., & Liu, J. (2012) · Pharmacology & Therapeutics · doi:10.1016/j.pharmthera.2012.10.003 · Cited by 185 · see citing works

Detection of tumor stem cell markers in pancreatic carcinoma cell lines.

Olempska, M., Eisenach, P. A., Ammerpohl, O., Ungefroren, H., Fändrich, F., & Kalthoff, H. (2007) · PubMed · Cited by 183 · see citing works

Gemcitabine: Progress in the Treatment of Pancreatic Cancer

Heinemann, V. (2000) · Oncology · doi:10.1159/000055290 · Cited by 166 · see citing works

Epithelial-Mesenchymal Transition (EMT) and Activated Extracellular Signal-regulated Kinase (p-Erk) in Surgically Resected Pancreatic Cancer

Javle, M. M., Gibbs, J. F., Iwata, K. K., Pak, Y., Rutledge, P., Yu, J., Black, J. D., Tan, D., & Khoury, T. (2007) · Annals of Surgical Oncology · doi:10.1245/s10434-007-9540-3 · Cited by 154 · see citing works

Signs and symptoms of pancreatic cancer: a population-based case-control study in the San Francisco Bay area

Holly, E. A., Chaliha, I., Bracci, P. M., & Gautam, M. (2004) · Clinical Gastroenterology and Hepatology · doi:10.1016/s1542-3565(04)00171-5 · Cited by 133 · see citing works

Pancreatic cancer stem cells: Emerging target for designing novel therapy

Li, Y., Kong, D., Ahmad, A., et al. (2012) · Cancer Letters · doi:10.1016/j.canlet.2012.03.018 · Cited by 131 · see citing works

Combination of salinomycin and gemcitabine eliminates pancreatic cancer cells

Zhang, G.-N., Liang, Y., Zhou, L.-J., et al. (2011) · Cancer Letters · doi:10.1016/j.canlet.2011.05.030 · Cited by 129 · see citing works

Pancreatic Cancer Cells Resistant to Chemoradiotherapy Rich in “Stem-Cell-Like” Tumor Cells

Du, Z., Qin, R., Wei, C., Wang, M., Shi, C., Tian, R., & Peng, C. (2010) · Digestive Diseases and Sciences · doi:10.1007/s10620-010-1340-0 · Cited by 127 · see citing works

Expression of Pluripotent Stem Cell Reprogramming Factors by Prostate Tumor Initiating Cells

Bae, K., Su, Z. Z., Frye, C., McClellan, S., Allan, R. W., Andrejewski, J. T., Kelley, V., Jorgensen, M., Steindler, D. A., Vieweg, J., et al. (2010) · The Journal of Urology · doi:10.1016/j.juro.2009.12.092 · Cited by 126 · see citing works

Salinomycin Selectively Targets ‘CD133+’ Cell Subpopulations and Decreases Malignant Traits in Colorectal Cancer Lines

Dong, T., Zhou, H., Wang, L., Feng, B., Lv, B., & Zheng, M.-H. (2011) · Annals of Surgical Oncology · doi:10.1245/s10434-011-1561-2 · Cited by 123 · see citing works

Overcoming nucleoside analog chemoresistance of pancreatic cancer: A therapeutic challenge

Hung, S. W., Mody, H. R., & Govindarajan, R. (2012) · Cancer Letters · doi:10.1016/j.canlet.2012.03.007 · Cited by 79 · see citing works

Salinomycin induces cell death and differentiation in head and neck squamous cell carcinoma stem cells despite activation of epithelial-mesenchymal transition and Akt

Kuo, S. Z., Blair, K. J., Rahimy, E., Kiang, A., Abhold, E. L., Fan, J., Wang‐Rodriguez, J., Altuna, X., & Ongkeko, W. M. (2012) · BMC Cancer · doi:10.1186/1471-2407-12-556 · Cited by 72 · see citing works

Antitumor activity and pharmacokinetics of liposomes containing lipophilic gemcitabine prodrugs.

Brusa, P., Immordino, M. L., Rocco, F., & Cattel, L. (2007) · PubMed · Cited by 68 · see citing works

Preparation, optimization and in vitro characterization of stearoyl-gemcitabine polymeric micelles: A comparison with its self-assembled nanoparticles

Daman, Z., Ostad, S. N., Amini, M., & Gilani, K. (2014) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2014.04.021 · Cited by 65 · see citing works

Clinical significance of vimentin-positive gastric cancer cells.

Fuyuhiro, Y., Yashiro, M., Noda, S., Kashiwagi, S., Matsuoka, J., Doi, Y., Kato, Y., Kubo, N., Ohira, M., & Hirakawa, K. (2010) · PubMed · Cited by 60 · see citing works

Liquid chromatography with ultraviolet detection of lasalocid, monensin, salinomycin and narasin in poultry feeds using pre-column derivatization

Dusi, G., & Gamba, V. (1999) · Journal of Chromatography A · doi:10.1016/s0021-9673(99)00044-8 · Cited by 55 · see citing works

iTEP Nanoparticle-Delivered Salinomycin Displays an Enhanced Toxicity to Cancer Stem Cells in Orthotopic Breast Tumors

Zhao, P., Dong, S., Bhattacharyya, J., & Chen, M. (2014) · Molecular Pharmaceutics · doi:10.1021/mp5002312 · Cited by 50 · see citing works

Mechanism of action of salinomycin on growth and migration in pancreatic cancer cell lines

He, L., Wang, F., Dai, W., et al. (2013) · Pancreatology · doi:10.1016/j.pan.2012.11.314 · Cited by 41 · see citing works

Nucleolin-Targeting AS1411 Aptamer-Modified Micelle for the Co-Delivery of Doxorubicin and miR-519c to Improve the Therapeutic Efficacy in Hepatocellular Carcinoma Treatment

Liang, X., Wang, Y., Shi, H., Dong, M., Han, H., & Li, Q. (2021) · International Journal of Nanomedicine · doi:10.2147/ijn.s304526 · Cited by 41 · see citing works

Gemcitabine Resistance is Associated with Epithelial-Mesenchymal Transition and Induction of HIF-1α in Pancreatic Cancer Cells

Wang, R., Cheng, L., Xia, J., Wang, Z., Wu, Q., & Wang, Z. (2014) · Current Cancer Drug Targets · doi:10.2174/1568009614666140226114015 · Cited by 56 · see citing works

Selenium Induces Pancreatic Cancer Cell Death Alone and in Combination with Gemcitabine

Wooten, D. J., Sinha, I., & Sinha, R. (2022) · Biomedicines · doi:10.3390/biomedicines10010149 · Cited by 11 · see citing works

Aberrant expression of circulating microRNAs in pancreatic cancer patients and in patients with gemcitabine resistance

Wang, S., Zhou, F., & Wang, L. (2014) · 国际外科学杂志 · doi:10.3760/cma.j.issn.1673-4203.2014.05.014

Natural Anti-Cancer Agents: Implications in Gemcitabine-Resistant Pancreatic Cancer Treatment

Marasini, B., & Sahu, R. P. (2017) · Mini-Reviews in Medicinal Chemistry · doi:10.2174/1389557517666170315124438 · Cited by 28 · see citing works

USP9X inhibition improves gemcitabine sensitivity in pancreatic cancer by inhibiting autophagy

Ma, T., Chen, W., Zhi, X., et al. (2018) · Cancer Letters · doi:10.1016/j.canlet.2018.08.010 · Cited by 69 · see citing works