Effect of Spinacia oleraceae L. and Perilla frutescens L. on Antioxidants and Lipid Peroxidation in an Intervention Study in Healthy Individuals
Abstract
Daily consumption of fruits and vegetables is frequently recommended to prevent several diseases. This health-promoting effect is considered to be in part due to the antioxidant content of fruits and vegetables and their ability to decrease oxidative stress. To investigate whether the ingestion of preparations from spinach or perilla, two carotenoid-rich leafy vegetables, is followed by an increase in carotenoid concentration and/or affects parameters of oxidative stress in human blood plasma. 12 healthy volunteers ingested a perilla- or spinach preparation for 10 days (5 mg lutein/d). We quantified antioxidant levels in plasma, kinetics of lipid peroxidation, MDA concentration, and total antioxidative capacity of plasma. We observed a significant increase in lutein content and a moderate increase (n.s.) in beta-carotene content in human blood plasma after consumption of spinach or perilla. The markers of lipid peroxidation tended to decrease, but no influence on antioxidative capacity of plasma could be detected. The high lutein content of perilla caused a more pronounced increase of lutein compared to spinach. Both vegetables seem to be able to influence lipid peroxidation in a beneficial manner.
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Consumption of spinach is not associated with adverse effects.
“Furthermore, the consumption of spinach is not associated with adverse effects [162,171,172,173,174,175,176,177,178].”
From Ecdysterone and Turkesterone—Compounds with Prominent Potential in Sport and Healthy Nutrition (2024) · cites this paper as [176]
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“[176] Calcium possibility to affect bioavailability of carotenoids from a vegetable matrix—spinach.”
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- Authors
- Schirrmacher, G., Skurk, T., Hauner, H., & Graßmann, J.
- Affiliations
- Technical University of Munich (DE)
- Else Kröner Fresenius Zentrum für Ernährungsmedizin (DE)
- Corresponding author
- Graßmann, Johanna
- Venue
- Plant Foods for Human Nutrition
- Published
- 2010-01-06
- Volume
- 65
- Issue
- 1
- Pages
- 71-76
- ISSN
- 0033-5134 (ISSN-L)
- 0921-9668
- 1573-9104
- OpenAlex
- W1982928548
- Cited by
- 32
- References
- 32
- Citations by year
- 2026: 1 · 2024: 2 · 2023: 1 · 2021: 1 · 2020: 4 · 2019: 5 · 2018: 1 · 2016: 4 · 2015: 2 · 2014: 1 · 2013: 3 · 2012: 1
- FWCI
- 2.08
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- www.springer.com/tdm (tdm)
- Locations
- Plant Foods for Human Nutrition (publishedVersion)
- PubMed (publishedVersion)
- mediaTUM – the media and publications repository of the Technical University Munich (Technical University Munich) (submittedVersion)
- Topics
- Health Sciences › Medicine › Biochemistry › Antioxidant Activity and Oxidative Stress
- Health Sciences › Medicine › Biochemistry › Phytochemicals and Antioxidant Activities
- Health Sciences › Medicine › Rehabilitation › Exercise and Physiological Responses
- Keywords
- spinach, Perilla frutescens, lutein, beta-carotene, carotenoids, lipid peroxidation, oxidative stress, antioxidant capacity, malondialdehyde, plasma carotenoid concentrations, dietary supplementation, leafy vegetables
- MeSH terms
- Adult, Antioxidants, Carotenoids, Humans, Malondialdehyde, Pilot Projects, Reference Values, Lutein, Lipid Peroxidation, Single-Blind Method, Oxidative Stress, Spinacia oleracea, beta Carotene, Plant Preparations, Perilla, Young Adult
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