Cited by 44Seed and Plant BiochemistryPhytochemicals and Antioxidant ActivitiesFood Science and Nutritional Studies

Plants of the genus Spinacia: From Bioactive Molecules to Food and Phytopharmacological Applications

Salehi, Bahare, Tumer, Tugba Boyunegmez, Ozleyen, Adem, Peron, Gregorio, Dall’Acqua, Stefano, Rajkovic, Jovana, Naz, Rabia, Nosheen, Asia +9 more·2019·Trends in Food Science & Technology

Abstract

Spinacia plants, including the most recognized species of the genus Spinacia oleacea L. (spinach), have high nutritional value and high content in phytochemicals, such as flavonoids, polyphenols, carotenoids, and ascorbic acid. However, the amount of these phytochemicals depends on several factors, such as genotype, climatic conditions, and agronomic practices, harvesting, storage temperature and time.This review focus on the therapeutic role of Spinacia genus as well as its contribution as food in industry. A special emphasis is also given to its biological activities including antioxidant and antimicrobial effects. Finally, the clinical efficacy of Spinacia plants, the respective roles, and mechanisms of bioactive compounds on human health are covered.Spinacia plants are rich in nitrate, thylakoids, glycoglycerolipids and their natural antioxidant mixture (NAO) shows renowned antioxidant, antiproliferative, anti-inflammatory, antimicrobial, anticancer and cardioprotective effects. Thus, the nutritional value and phytochemical composition of Spinacia plants make them an excellent matrix to be used in traditional medicine as also as a natural preservative ingredient in food.

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Crossref · 10.1016/j.tifs.2019.03.028

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  • Spinacia oleracea has a wide variety of potential functionalities, mainly antioxidant, antimicrobial, anticancer, anti-obesity, hypoglycemic, and hypolipidemic.

    “Due to the wide variety of bioactive and phytochemical compounds, S. oleracea has a wide variety of potential functionalities, mainly antioxidant, antimicrobial, anticancer, anti-obesity, hypoglycemic, and hypolipidemic [146,149,151].”

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Authors
Salehi, B., Tumer, T. B., Ozleyen, A., Peron, G., Dall’Acqua, S., Rajkovic, J., Naz, R., Nosheen, A., Mudau, F. N., Labanca, F., Milella, L., de Tommasi, N., Coutinho, H. D., Sharifi-Rad, J., Verma, D. R., Martorell, M., & Martins, N.
Affiliations
  • Bam University of Medical Sciences (IR)
  • Çanakkale Onsekiz Mart Üniversitesi (TR)
  • University of Padua (IT)
  • COMSATS University Islamabad (PK)
  • University of South Africa (ZA)
  • University of Basilicata (IT)
  • Universidade Regional do Cariri (BR)
  • University of Concepción (CL)
  • Universidade do Porto (PT)
Corresponding author
  • Martorell, Miquel
  • Martins, Natália
Venue
Trends in Food Science & Technology
Publisher
Elsevier BV
Published
2019-06
Volume
88
Pages
260-273
ISSN
0924-2244 (ISSN-L)
OpenAlex
W2927733189
Cited by
44
References
113
Citations by year
2026: 5 · 2025: 9 · 2024: 6 · 2023: 6 · 2022: 5 · 2021: 5 · 2020: 6 · 2019: 2
FWCI
3.47
Type
journal article
Language
en
Open access
closed
Locations
  • Trends in Food Science & Technology (publishedVersion)
  • Çanakkale Onsekiz Mart University AVESIS (submittedVersion)
  • CINECA IRIS Institutional Research Information System (University of Basilicata) (submittedVersion)
  • Institutional Research Information System (Università degli Studi di Brescia) (submittedVersion)
  • Padua Research Archive (University of Padova) (submittedVersion)
Funders
  • CONICYT PIA/APOYO CCTE (AFB170007)
  • Portuguese Foundation for Science and Technology (UID/BIM/04293/2013)
  • NORTE2020—Programa Operacional Regional do Norte (NORTE-01-0145-FEDER-000012)
Topics
  • Life Sciences › Agricultural and Biological Sciences › Food Science › Seed and Plant Biochemistry
  • Health Sciences › Medicine › Biochemistry › Phytochemicals and Antioxidant Activities
  • Health Sciences › Nursing › Nutrition and Dietetics › Food Science and Nutritional Studies
Keywords
Spinacia, spinach, phytochemicals, flavonoids, polyphenols, carotenoids, vitamin C, antioxidant activity, antimicrobial activity, nitrate, thylakoids, glycoglycerolipids, anticancer effects, cardioprotection, anti-inflammatory activity, antiproliferative activity, traditional medicine, natural food preservatives, food industry applications

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