The DOI matches its Crossref record; 26 of the 26 references it cites were found in a registry or an index.
The effect of continuous positive airway pressure on glucose control in diabetic patients with severe obstructive sleep apnea
Abstract
Obstructive sleep apnea (OSA) is independently associated with glucose intolerance and insulin resistance, and recent studies have shown that continuous positive airway pressure (CPAP) improves insulin sensitivity. The objective of this study was to describe the change in glycosylated hemoglobin (HbA1c) after treatment with CPAP in patients with type 2 diabetes mellitus and OSA. To test this hypothesis, we performed a retrospective analysis of 38 patients seen in the sleep clinic of an urban public teaching hospital. All patients had OSA and type 2 diabetes mellitus, and their diabetic medication regimen had remained unchanged during the period of CPAP therapy. Sixty-one percent were men, body mass index was 42+/-9.5 kg/m(2), and the Apnea-Hypopnea Index was 53+/-36 per hour. HbA1c before therapy with CPAP was 7.8+/-1.4% and decreased to 7.3+/-1.3% after 134+/-119 days of therapy (p<0.001). Treatment with CPAP leads to a clinically significant drop in HbA1c in patients with type 2 diabetes mellitus and severe OSA.
Overview
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“Improvement in glycemic control has been demonstrated after 3 months of CPAP use, with improvement related to number of hours of nightly CPAP use(107, 108).”
From Sleep: important considerations for the prevention of cardiovascular disease (2016) · cites this paper as [107]
Citations
Cites
Rechtschaffen, A. (1968) · Medical Entomology and Zoology · Cited by 11,772
Glucose clamp technique: a method for quantifying insulin secretion and resistance.
DeFronzo, R. A., Tobin, J. D., & Andres, R. (1979) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.1979.237.3.e214 · Cited by 7,425
McNicholas, W. T., Strohl, K. P., White, D. P., Levy, P. A., Schmidt, W., Wheatley, J. R., Redline, S. S., Carley, D. W., Buysse, D. J., Young, T. B., et al. (1999) · PubMed · Cited by 3,665
Boulé, N. G., Haddad, E., Kenny, G. P., Wells, G. A., & Sigal, R. J. (2001) · JAMA · doi:10.1001/jama.286.10.1218 · Cited by 1,889
Yki-Järvinen, H. (2004) · New England Journal of Medicine · doi:10.1056/nejmra041001 · Cited by 1,830
Obstructive Sleep Apnea Is Independently Associated with Insulin Resistance
Ip, M. S. M., Lam, B., Ng, M. M. T., Lam, W. K., Tsang, K. W. T., & Lam, K. S. L. (2002) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/ajrccm.165.5.2103001 · Cited by 1,300
Vgontzas, A. N., Papanicolaou, D. A., Bixler, E. O., Hopper, K. D., Lotsikas, A. J., LIN, H., Kales, A., & Chrousos, G. P. (2000) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.85.3.6484 · Cited by 1,209
Punjabi, N. M. (2004) · American Journal of Epidemiology · doi:10.1093/aje/kwh261 · Cited by 1,107
Sleep-disordered Breathing and Insulin Resistance in Middle-aged and Overweight Men
Punjabi, N. M., Sorkin, J. D., Katzel, L. I., Goldberg, A. P., Schwartz, A. R., & SMITH, P. L. (2002) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/ajrccm.165.5.2104087 · Cited by 961
Harsch, I. A., Schahin, S. P., Radespiel-Tröger, M., Weintz, O., Jahreiß, H., Fuchs, F. S., Wiest, G. H., Hahn, E. G., Lohmann, T., Konturek, P. C., et al. (2004) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.200302-206oc · Cited by 583
Babu, A. R., Herdegen, J., Fogelfeld, L., Shott, S., & Mazzone, T. (2005) · Archives of Internal Medicine · doi:10.1001/archinte.165.4.447 · Cited by 453 · cited 3×
“Our findings are consistent with a recent prospective study which demonstrated the effectiveness of CPAP therapy in improving postprandial glucose levels and HbA1c in type 2 diabetics with OSA [16].”
BackgroundMethodResultInfluentialSelf-citationSnoring and sleep apnoea in men: association with central obesity and hypertension.
Grunstein, R. R., Wilcox, I., Yang, T. S., Gould, Y., & Hedner, J. A. (1993) · PubMed · Cited by 331
Snoring as a Risk Factor for Type II Diabetes Mellitus: A Prospective Study
Al‐Delaimy, W. K., Manson, J. E., Willett, W. C., Stampfer, M. J., & Hu, F. B. (2002) · American Journal of Epidemiology · doi:10.1093/aje/155.5.387 · Cited by 328
Brooks, B. (1994) · Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.79.6.1681 · Cited by 295
Sleep‐disordered breathing and glucose metabolism in hypertensive men: a population‐based study
Elmasry, A., Lindberg, E., Berne, C., Janson, C., Gíslason, Þ., Tageldin, M. A., & Boman, G. (2001) · Journal of Internal Medicine · doi:10.1046/j.1365-2796.2001.00787.x · Cited by 286
Harsch, I. A., Schahin, S. P., Brückner, K., Radespiel-Tröger, M., Fuchs, F. S., Hahn, E. G., Konturek, P. C., Lohmann, T., & Ficker, J. H. (2004) · Respiration · doi:10.1159/000077423 · Cited by 219
Elmasry, A., Janson, C., Lindberg, E., Gíslason, Þ., Tageldin, M. A., & Boman, G. (2000) · Journal of Internal Medicine · doi:10.1046/j.1365-2796.2000.00683.x · Cited by 196
Insulin Resistance and Sleep-Disordered Breathing in Healthy Humans
Stoohs, R. A., Facchini, F., & Guilleminault, C. (1996) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/ajrccm.154.1.8680675 · Cited by 173
CPAP treatment does not affect glucose–insulin metabolism in sleep apneic patients
Smurra, M. V., Philip, P., Taillard, J., Guilleminault, C., Bioulac, B. H., & Gin, H. (2001) · Sleep Medicine · doi:10.1016/s1389-9457(00)00079-4 · Cited by 116
The severity of obstructive sleep apnoea is associated with insulin resistance
Tiihonen, M., Partinen, M., & Närvänen, S. (1993) · Journal of Sleep Research · doi:10.1111/j.1365-2869.1993.tb00062.x · Cited by 113
Soluble leptin receptor and insulin resistance as determinant of sleep apnea
Manzella, D., Parillo, M., Razzino, T., Gnasso, P., BUONANNO, S., Gargiulo, A. M., Caputi, M., & Paolisso, G. (2002) · International Journal of Obesity · doi:10.1038/sj.ijo.0801939 · Cited by 75
Molyneaux, L. M., Constantino, M., McGill, M. J., Zilkens, R., & Yue, D. K. (1998) · Diabetes Research and Clinical Practice · doi:10.1016/s0168-8227(98)00095-3 · Cited by 50
Snoring, sympathetic activity and cardiovascular risk factors in a 70 year old population
Jennum, P., Schultz‐Larsen, K., & Christensen, N. J. (1993) · European Journal of Epidemiology · doi:10.1007/bf00209524 · Cited by 43
Flagged first, then by citations
Cited by
Sorted by citations
McNicholas, W. T., Bonsignore, M. R., & the Management Committee of EU COST ACTION B26 (2007) · European Respiratory Journal · doi:10.1183/09031936.00027406 · Cited by 911
Effects of poor and short sleep on glucose metabolism and obesity risk
Spiegel, K., Tasali, E., Leproult, R., & Van Cauter, E. (2009) · Nature Reviews Endocrinology · doi:10.1038/nrendo.2009.23 · Cited by 857
Handelsman, Y., Bloomgarden, Z. T., Grunberger, G., Umpierrez, G. E., Zimmerman, R. S., Bailey, T. S., Blonde, L., Bray, G. A., Cohen, A. J., Dagogo-Jack, S. E., et al. (2015) · Endocrine Practice · doi:10.4158/ep15672.gl · Cited by 646
Handelsman, Y., Bloomgarden, Z. T., Grunberger, G., Umpierrez, G., Zimmerman, R. S., Bailey, T. S., Blonde, L., Bray, G. A., Cohen, A. J., Dagogo-Jack, S., et al. (2015) · Endocrine Practice · doi:10.4158/ep15672.glsuppl · Cited by 559
Handelsman, Y., Mechanick, J. I., Blonde, L., Grunberger, G., Bloomgarden, Z. T., Bray, G. A., Dagogo-Jack, S., Davidson, J. A., Einhorn, D., Ganda, O., et al. (2011) · Endocrine Practice · doi:10.4158/ep.17.s2.1 · Cited by 513
Metadata
- Authors
- Hassaballa, H. A., Tulaimat, A., Herdegen, J. J., & Mokhlesi, B.
- Affiliations
- Rush University Medical Center (US)
- John H. Stroger, Jr. Hospital of Cook County (US)
- Corresponding author
- Tulaimat, Aiman
- Venue
- Sleep And Breathing
- Published
- 2005-11-08
- Volume
- 9
- Issue
- 4
- Pages
- 176-180
- ISSN
- 1520-9512 (ISSN-L)
- 1522-1709
- OpenAlex
- W2091933728
- Cited by
- 142
- References
- 26
- Citations by year
- 2026: 3 · 2025: 2 · 2023: 2 · 2022: 4 · 2021: 2 · 2020: 3 · 2019: 3 · 2018: 5 · 2017: 5 · 2016: 11 · 2015: 17 · 2014: 10 · 2013: 8 · 2012: 14
- FWCI
- 4.59
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- www.springer.com/tdm (tdm)
- Locations
- Sleep And Breathing (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Physiology (medical) › Obstructive Sleep Apnea Research
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Sleep and related disorders
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Treatment and Management
- Keywords
- continuous positive airway pressure, obstructive sleep apnea, type 2 diabetes, glycemic control, HbA1c, insulin resistance, impaired glucose tolerance, CPAP therapy
- MeSH terms
- Blood Glucose, Diabetes Mellitus, Female, Humans, Male, Middle Aged, Retrospective Studies, Severity of Illness Index, Body Mass Index, Sleep Apnea, Obstructive, Continuous Positive Airway Pressure
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
