The DOI matches its Crossref record; 72 of the 73 references it cites were found in a registry or an index.
Symptom Burden, Depression, and Spiritual Well-Being: A Comparison of Heart Failure and Advanced Cancer Patients
Open accessAbstract
Background A lower proportion of patients with chronic heart failure receive palliative care compared to patients with advanced cancer.Objective We examined the relative need for palliative care in the two conditions by comparing symptom burden, psychological well-being, and spiritual well-being in heart failure and cancer patients.Design This was a cross-sectional study.Participants Sixty outpatients with symptomatic heart failure and 30 outpatients with advanced lung or pancreatic cancer.Measurements Symptom burden (Memorial Symptom Assessment Scale-Short Form), depression symptoms (Geriatric Depression Scale-Short Form), and spiritual well-being (Functional Assessment of Chronic Illness Therapy-Spiritual Well-Being scale).Main results Overall, the heart failure patients and the cancer patients had similar numbers of physical symptoms (9.1 vs. 8.6, p = 0.79), depression scores (3.9 vs. 3.2, p = 0.53), and spiritual well-being (35.9 vs. 39.0, p = 0.31) after adjustment for age, gender, marital status, education, and income. Symptom burden, depression symptoms, and spiritual well-being were also similar among heart failure patients with ejection fraction < or =30, ejection fraction >30, and cancer patients. Heart failure patients with worse heart failure-related health status had a greater number of physical symptoms (13.2 vs. 8.6, p = 0.03), higher depression scores (6.7 vs. 3.2, p = 0.001), and lower spiritual well-being (29.0 vs. 38.9, p < 0.01) than patients with advanced cancer.Conclusions Patients with symptomatic heart failure and advanced cancer have similar needs for palliative care as assessed by symptom burden, depression, and spiritual well-being. This implies that heart failure patients, particularly those with more severe heart failure, need the option of palliative care just as cancer patients do.
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“As symptoms worsen, many CHF patients become dependent on carers, which adversely affects their sense of identity and will to live. 6 , 15”
From Prioritizing symptom management in the treatment of chronic heart failure (2020) · cites this paper as [6]
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“The symptom burden for CHF patients has been likened to those with advanced cancer or acquired immune deficiency syndrome, 6 , 12”
From Prioritizing symptom management in the treatment of chronic heart failure (2020) · cites this paper as [6]
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“Despite optimal medical management and device therapy, patients often have persistent symptoms and long‐term reductions in quality of life (QoL)”
From Prioritizing symptom management in the treatment of chronic heart failure (2020) · cites this paper as [6]
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The Effect of Cardiac Resynchronization on Morbidity and Mortality in Heart Failure
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“Heart failure patients often have persistent prototypical symptoms, such as shortness of breath and fatigue, despite optimal medical management and device therapy.(51,52) Many also have concurrent symptoms such as pain, constipation, and dry mouth that contribute to diminished quality of life.”
BackgroundACC/AHA 2005 Guideline Update for the Diagnosis and Management of Chronic Heart Failure in the Adult
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Update on Prevalence of Pain in Patients With Cancer: Systematic Review and Meta-Analysis
Everdingen, M. H. J. V. D. B.-V., Hochstenbach, L. M. J., Joosten, E. A. J., Tjan‐Heijnen, V. C. G., & Janssen, D. J. A. (2016) · Journal of Pain and Symptom Management · doi:10.1016/j.jpainsymman.2015.12.340 · Cited by 1,671
Rangaswami, J., Bhalla, V., Blair, J. E., Chang, T. I., Costa, S. P., Lentine, K. L., Lerma, E. V., Mezue, K. N., Molitch, M. E., Müllens, W., et al. (2019) · Circulation · doi:10.1161/cir.0000000000000664 · Cited by 1,535
Palliative Care in Heart Failure
Rogers, J. G., Patel, C. B., Mentz, R. J., Granger, B. B., Steinhauser, K. E., Fiuzat, M., Adams, P. A., Speck, A., Johnson, K. S., Krishnamoorthy, A., et al. (2017) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2017.05.030 · Cited by 603
Miaskowski, C. A., Barsevick, A. M., Berger, A. M., Casagrande, R. J., Grady, P. A., Jacobsen, P. B., Kutner, J. S., Patrick, D. L., Zimmerman, L. M., Xiao, C., et al. (2016) · JNCI Journal of the National Cancer Institute · doi:10.1093/jnci/djw253 · Cited by 507
Self-citationDunbar, S. B., Khavjou, O., Bakas, T., Hunt, G. G., Kirch, R., Leib, A. R., Morrison, R. S., Poehler, D. C., Roger, V. L., & Whitsel, L. P. (2018) · Circulation · doi:10.1161/cir.0000000000000570 · Cited by 344
Metadata
- Authors
- Bekelman, D. B., Rumsfeld, J. S., Havranek, E. P., Yamashita, T. E., Hutt, E., Gottlieb, S. H., Dy, S. M., & Kutner, J. S.
- Affiliations
- University of Colorado Anschutz (US)
- VA Eastern Colorado Health Care System (US)
- Denver Health Medical Center (US)
- Johns Hopkins Bayview Medical Center (US)
- Johns Hopkins University (US)
- Corresponding author
- Bekelman, David B.
- Venue
- Journal of General Internal Medicine
- Published
- 2009-03-14
- Volume
- 24
- Issue
- 5
- Pages
- 592-598
- ISSN
- 0884-8734 (ISSN-L)
- 1525-1497
- PMC
- PMC2669863
- OpenAlex
- W2064454083
- Cited by
- 306
- References
- 73
- Citations by year
- 2026: 12 · 2025: 11 · 2024: 17 · 2023: 20 · 2022: 21 · 2021: 18 · 2020: 20 · 2019: 21 · 2018: 24 · 2017: 20 · 2016: 20 · 2015: 23 · 2014: 26 · 2013: 15 · 2012: 18
- FWCI
- 12.77
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- www.springer.com/tdm (tdm)
- Locations
- Journal of General Internal Medicine (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Funders
- American Heart Association
- Johns Hopkins University
- National Institutes of Health
- Topics
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Palliative Care and End-of-Life Issues
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Palliative and Oncologic Care
- Social Sciences › Health › Religion, Spirituality, and Psychology
- Keywords
- heart failure, advanced cancer, palliative care, symptom burden, depression, spiritual well-being, psychological well-being, ejection fraction, lung cancer, pancreatic cancer
- MeSH terms
- Aged, Aged, 80 and over, Cross-Sectional Studies, Depression, Female, Heart Failure, Humans, Male, Middle Aged, Neoplasms, Palliative Care, Quality of Life, Spirituality
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