Cited by 307Palliative Care and End-of-Life IssuesPalliative and Oncologic CareReligion, Spirituality, and Psychology

The DOI matches its Crossref record; 72 of the 73 references it cites were found in a registry or an index.

Symptom Burden, Depression, and Spiritual Well-Being: A Comparison of Heart Failure and Advanced Cancer Patients

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Abstract

Background A lower proportion of patients with chronic heart failure receive palliative care compared to patients with advanced cancer.Objective We examined the relative need for palliative care in the two conditions by comparing symptom burden, psychological well-being, and spiritual well-being in heart failure and cancer patients.Design This was a cross-sectional study.Participants Sixty outpatients with symptomatic heart failure and 30 outpatients with advanced lung or pancreatic cancer.Measurements Symptom burden (Memorial Symptom Assessment Scale-Short Form), depression symptoms (Geriatric Depression Scale-Short Form), and spiritual well-being (Functional Assessment of Chronic Illness Therapy-Spiritual Well-Being scale).Main results Overall, the heart failure patients and the cancer patients had similar numbers of physical symptoms (9.1 vs. 8.6, p = 0.79), depression scores (3.9 vs. 3.2, p = 0.53), and spiritual well-being (35.9 vs. 39.0, p = 0.31) after adjustment for age, gender, marital status, education, and income. Symptom burden, depression symptoms, and spiritual well-being were also similar among heart failure patients with ejection fraction < or =30, ejection fraction >30, and cancer patients. Heart failure patients with worse heart failure-related health status had a greater number of physical symptoms (13.2 vs. 8.6, p = 0.03), higher depression scores (6.7 vs. 3.2, p = 0.001), and lower spiritual well-being (29.0 vs. 38.9, p < 0.01) than patients with advanced cancer.Conclusions Patients with symptomatic heart failure and advanced cancer have similar needs for palliative care as assessed by symptom burden, depression, and spiritual well-being. This implies that heart failure patients, particularly those with more severe heart failure, need the option of palliative care just as cancer patients do.

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  1. Yesavage JA. Geriatric Depression Scale. Psychopharmacol Bull. 1988;24(4):709–11.

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Authors
Bekelman, D. B., Rumsfeld, J. S., Havranek, E. P., Yamashita, T. E., Hutt, E., Gottlieb, S. H., Dy, S. M., & Kutner, J. S.
Affiliations
  • University of Colorado Anschutz (US)
  • VA Eastern Colorado Health Care System (US)
  • Denver Health Medical Center (US)
  • Johns Hopkins Bayview Medical Center (US)
  • Johns Hopkins University (US)
Corresponding author
Bekelman, David B.
Venue
Journal of General Internal Medicine
Published
2009-03-14
Volume
24
Issue
5
Pages
592-598
ISSN
  • 0884-8734 (ISSN-L)
  • 1525-1497
OpenAlex
W2064454083
Cited by
306
References
73
Citations by year
2026: 12 · 2025: 11 · 2024: 17 · 2023: 20 · 2022: 21 · 2021: 18 · 2020: 20 · 2019: 21 · 2018: 24 · 2017: 20 · 2016: 20 · 2015: 23 · 2014: 26 · 2013: 15 · 2012: 18
FWCI
12.77
Type
journal article
Language
en
Open access
Locations
  • Journal of General Internal Medicine (publishedVersion)
  • PubMed Central (publishedVersion)
  • PubMed (publishedVersion)
Funders
  • American Heart Association
  • Johns Hopkins University
  • National Institutes of Health
Topics
  • Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Palliative Care and End-of-Life Issues
  • Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Palliative and Oncologic Care
  • Social Sciences › Health › Religion, Spirituality, and Psychology
Keywords
heart failure, advanced cancer, palliative care, symptom burden, depression, spiritual well-being, psychological well-being, ejection fraction, lung cancer, pancreatic cancer
MeSH terms
Aged, Aged, 80 and over, Cross-Sectional Studies, Depression, Female, Heart Failure, Humans, Male, Middle Aged, Neoplasms, Palliative Care, Quality of Life, Spirituality

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