Mouse models of neurodegenerative disease: preclinical imaging and neurovascular component

A multifunctional therapeutic approach to disease modification in multiple familial mouse models and a novel sporadic model of Alzheimer’s disease

Luo, J., Lee, S., VandeVrede, L. A., Qin, Z., Aissa, M. B., Larson, J., Teich, A. F., Arancio, O., D’Souza, Y., Elharram, A., et al. (2016) · Molecular Neurodegeneration · doi:10.1186/s13024-016-0103-6 · Cited by 37

T 2 -Weighted MRI Detects Presymptomatic Pathology in the SOD1 Mouse Model of ALS

Evans, M. C., Serres, S., Khrapitchev, A. A., Stolp, H. B., Anthony, D. C., Talbot, K., Turner, M. R., & Sibson, N. R. (2014) · Journal of Cerebral Blood Flow & Metabolism · doi:10.1038/jcbfm.2014.19 · Cited by 37

Comparison of [18F]FDOPA, [18F]FMT and [18F]FECNT for imaging dopaminergic neurotransmission in mice

Honer, M., Hengerer, B., Blagoev, M., Hintermann, S., Waldmeier, P. C., Schubiger, P. A., & Ametamey, S. M. (2006) · Nuclear Medicine and Biology · doi:10.1016/j.nucmedbio.2006.04.005 · Cited by 37

Head and neck veins of the mouse. A magnetic resonance, micro computed tomography and high frequency color Doppler ultrasound study

Mancini, M., Greco, A., Tedeschi, E., Palma, G., Ragucci, M., Bruzzone, M. G., Coda, A. R. D., Torino, E., Scotti, A., Zucca, I., et al. (2015) · PLoS ONE · doi:10.1371/journal.pone.0129912 · Cited by 36

Behavioral testing strategies in a localized animal model of multiple sclerosis

Buddeberg, B. S., Kerschensteiner, M., Merkler, D., Stadelmann, C., & Schwab, M. E. (2004) · Journal of Neuroimmunology · doi:10.1016/j.jneuroim.2004.05.006 · Cited by 36

The effects of paraquat on regional brain neurotransmitter activity, hippocampal BDNF and behavioural function in female mice

Litteljohn, D., Nelson, E., Bethune, C., & Hayley, S. P. (2011) · Neuroscience Letters · doi:10.1016/j.neulet.2011.07.041 · Cited by 36

Riluzole prolongs survival and delays muscle strength deterioration in mice with progressive motor neuronopathy (pmn)

Kennel, P., Revah, F., Böhme, G. A., Bejuit, R., Gallix, P., Stutzmann, J. M., Impérato, A., & Pratt, J. (2000) · Journal of the Neurological Sciences · doi:10.1016/s0022-510x(00)00423-8 · Cited by 36

Histological–MRI correlation in the primary motor cortex of patients with amyotrophic lateral sclerosis

Meadowcroft, M. D., Mutic, N. J., Bigler, D. C., Wang, J., Simmons, Z., Connor, J. R., & Yang, Q. X. (2014) · Journal of Magnetic Resonance Imaging · doi:10.1002/jmri.24582 · Cited by 36

High‐resolution in vivo imaging of microglia using a versatile nongenetically encoded marker

Schwendele, B., Brawek, B., Hermes, M., & Garaschuk, O. (2012) · European Journal of Immunology · doi:10.1002/eji.201242436 · Cited by 35

Longitudinal Tracking of Human Fetal Cells Labeled with Super Paramagnetic Iron Oxide Nanoparticles in the Brain of Mice with Motor Neuron Disease

Bigini, P., Diana, V., Barbera, S., Fumagalli, E. R., Micotti, E., Sitia, L., Paladini, A., Bisighini, C., Grada, L. D., Coloca, L., et al. (2012) · PLoS ONE · doi:10.1371/journal.pone.0032326 · Cited by 35

Anatomical and Functional Phenotyping of Mice Models of Alzheimer's Disease by MR Microscopy

Benveniste, H., Ma, Y., Dhawan, J., Gifford, A. J., Smith, S. D. B., Feinstein, I., Du, C., Grant, S. C., & Hof, P. R. (2007) · Annals of the New York Academy of Sciences · doi:10.1196/annals.1379.006 · Cited by 34

Movies of dopamine transporter occupancy with ultra-high resolution focusing pinhole SPECT

Vastenhouw, B., van der Have, F., van der Linden, A. J. A., von Oerthel, L., Booij, J., Burbach, J. P. H., Smidt, M. P., & Beekman, F. J. (2007) · Molecular Psychiatry · doi:10.1038/sj.mp.4002028 · Cited by 34

Cerebral Amyloid Angiopathy Increases Susceptibility to Infarction After Focal Cerebral Ischemia in Tg2576 Mice

Milner, E., Zhou, M., Johnson, A. W., Vellimana, A. K., Greenberg, J. K., Holtzman, D. M., Han, B. H., & Zipfel, G. J. (2014) · Stroke · doi:10.1161/strokeaha.114.006078 · Cited by 33

FDG–PET imaging, EEG and sleep phenotypes as translational biomarkers for research in Alzheimer's disease

Platt, B., Welch, A., & Riedel, G. (2011) · Biochemical Society Transactions · doi:10.1042/bst0390874 · Cited by 33

Precision Medicine in Multiple Sclerosis: Future of PET Imaging of Inflammation and Reactive Astrocytes

Poutiainen, P., Jaronen, M., Quintana, F. J., & Brownell, A. (2016) · Frontiers in Molecular Neuroscience · doi:10.3389/fnmol.2016.00085 · Cited by 33

Animal models of Huntington's disease: implications in uncovering pathogenic mechanisms and developing therapies

Wang, L., & Qin, Z. (2006) · Acta Pharmacologica Sinica · doi:10.1111/j.1745-7254.2006.00410.x · Cited by 32

Development of Alzheimer-disease neuroimaging-biomarkers using mouse models with amyloid-precursor protein-transgene expression

Teipel, S. J., Buchert, R., Thome, J., Hampel, H. J., & Pahnke, J. (2011) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2011.05.004 · Cited by 31

Gelsolin decreases actin toxicity and inflammation in murine multiple sclerosis

Li-ChunHsieh, K., Schob, S., Zeller, M. W. G., Pulli, B., Ali, M. Y. J., Wang, C., Chiou, T. T.-Y., Tsang, Y., Lee, P., Stossel, T. P., et al. (2015) · Journal of Neuroimmunology · doi:10.1016/j.jneuroim.2015.08.006 · Cited by 31

The isotropic fractionator provides evidence for differential loss of hippocampal neurons in two mouse models of Alzheimer’s disease

Brautigam, H., Steele, J. W., Westaway, D., Fraser, P. E., George-Hyslop, P. H. S., Gandy, S., Hof, P. R., & Dickstein, D. L. (2012) · Molecular Neurodegeneration · doi:10.1186/1750-1326-7-58 · Cited by 31

Quantitative evaluation of MRI and histological characteristics of the 5xFAD Alzheimer mouse brain

Spencer, N. G., Bridges, L., Elderfield, K., Amir, K., Austen, B., & Howe, F. A. (2013) · NeuroImage · doi:10.1016/j.neuroimage.2013.02.071 · Cited by 30

Neurovascular Changes in Acute, sub-Acute and Chronic Mouse Models of Parkinson’s Disease

Sarkar, S., Raymick, J. B., Mann, D., Bowyer, J. F., Hanig, J. P., Schmued, L. C., Paule, M. G., & Chigurupati, S. (2014) · Current Neurovascular Research · doi:10.2174/1567202610666131124234506 · Cited by 30

Rotarod motor performance and advanced spinal cord lesion image analysis refine assessment of neurodegeneration in experimental autoimmune encephalomyelitis

van den Berg, R., Laman, J. D., van Meurs, M., Hintzen, R. Q., & Hoogenraad, C. C. (2016) · Journal of Neuroscience Methods · doi:10.1016/j.jneumeth.2016.01.013 · Cited by 30

Longitudinal in vivo MRI in a Huntington’s disease mouse model: Global atrophy in the absence of white matter microstructural damage

Steventon, J. J., Trueman, R. C., Ma, D., Yhnell, E., Bayram-Weston, Z., Marc Modat, A., Cardoso, M. J., Sebastien Ourselin, A., Lythgoe, M. F., Stewart, A., et al. (2016) · Scientific Reports · doi:10.1038/srep32423 · Cited by 30

Evidence that small molecule enhancement of β-hexosaminidase activity corrects the behavioral phenotype in Dutch APPE693Q mice through reduction of ganglioside-bound Aβ

Knight, E. M., Williams, H. N., Stevens, A. C., Kim, S. H., Kottwitz, J., Morant, A., Steele, J., Klein, W. L., Yanagisawa, K., BOYD, R. E., et al. (2014) · Molecular Psychiatry · doi:10.1038/mp.2014.135 · Cited by 29

Spatiotemporal mapping of brain atrophy in mouse models of Huntington's disease using longitudinal in vivo magnetic resonance imaging

Aggarwal, M., Duan, W., Hou, Z., Rakesh, N., Peng, Q., Ross, C. A., Miller, M. I., Mori, S., & Zhang, J. (2012) · NeuroImage · doi:10.1016/j.neuroimage.2012.01.141 · Cited by 28

Three dimensional magnetic resonance microangiography of rat neurovasculature

Mellin, A. F., Cofer, G. P., Smith, B. R., Suddarth, S. A., Hedlund, L. W., & Johnson, G. A. (1994) · Magnetic Resonance in Medicine · doi:10.1002/mrm.1910320208 · Cited by 27

Magnetization transfer ratio does not correlate to myelin content in the brain in the MOG-EAE mouse model

Fjær, S., Bø, L., Myhr, K., Torkildsen, Ø., & Wergeland, S. (2015) · Neurochemistry International · doi:10.1016/j.neuint.2015.02.006 · Cited by 27

The olfactory tubing maze: a new apparatus for studying learning and memory processes in mice

Roman, F. S., Marchetti, E., Bouquerel, A., & Soumireu-Mourat, B. (2002) · Journal of Neuroscience Methods · doi:10.1016/s0165-0270(02)00094-8 · Cited by 27

Tg-SwDI Transgenic Mice Exhibit Novel Alterations in AβPP Processing, Aβ Degradation, and Resilient Amyloid Angiopathy

Vickle, G. D. V., Esh, C. L., Daugs, I. D., Kokjohn, T. A., Kalback, W. M., Patton, R., Luehrs, D. C., Walker, D. G., Lue, L., Beach, T. G., et al. (2008) · American Journal Of Pathology · doi:10.2353/ajpath.2008.071191 · Cited by 27

Predictive value of dopamine transporter SPECT imaging with [123I]PE2I in patients with subtle parkinsonian symptoms

Ziebell, M., Andersen, B. B., Thomsen, G. K., Pinborg, L. H., Karlsborg, M., Hasselbalch, S. G., & Knudsen, G. M. (2011) · European Journal of Nuclear Medicine and Molecular Imaging · doi:10.1007/s00259-011-1976-9 · Cited by 27

Optical tomographic imaging of near infrared imaging agents quantifies disease severity and immunomodulation of experimental autoimmune encephalomyelitis in vivo

Eaton, V. L., Vasquez, K. O., Goings, G. E., Hunter, Z. N., Peterson, J. D., & Miller, S. D. (2013) · Journal of Neuroinflammation · doi:10.1186/1742-2094-10-138 · Cited by 27

Regional vulnerability in Huntington's disease: fMRI-guided molecular analysis in patients and a mouse model of disease

Lewandowski, N. M., Bordelon, Y. M., Brickman, A. M., Angulo, S. L., Khan, U., Muraskin, J., Griffith, E. Y., Wasserman, P., Menalled, L., Vonsattel, J. P., et al. (2012) · Neurobiology of Disease · doi:10.1016/j.nbd.2012.11.014 · Cited by 26

Magnetization transfer contrast imaging reveals amyloid pathology in Alzheimer's disease transgenic mice

Bigot, C., Vanhoutte, G., Verhoye, M., & der Linden, A. V. (2013) · NeuroImage · doi:10.1016/j.neuroimage.2013.10.056 · Cited by 26

Pharmacokinetics and Amyloid Plaque Targeting Ability of a Novel Peptide-Based Magnetic Resonance Contrast Agent in Wild-Type and Alzheimer’s Disease Transgenic Mice

Kandimalla, K. K., Wengenack, T. M., Curran, G. L., Gilles, E. J., & Poduslo, J. F. (2007) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1124/jpet.107.119883 · Cited by 26

The Wobbler Mouse Model of Amyotrophic Lateral Sclerosis (ALS) Displays Hippocampal Hyperexcitability, and Reduced Number of Interneurons, but No Presynaptic Vesicle Release Impairments

Thielsen, K. D., Moser, J., Schmitt‐John, T., Jensen, M. S., Jensen, K., & Holm, M. M. (2013) · PLoS ONE · doi:10.1371/journal.pone.0082767 · Cited by 25

In vivo PET imaging of beta-amyloid deposition in mouse models of Alzheimer's disease with a high specific activity PET imaging agent [18F]flutemetamol

Snellman, A., Rokka, J., Lopez‐Picon, F. R., Eskola, O., Salmona, M., Forloni, G., Scheinin, M., Solin, O. H., Rinne, J. O., & Haaparanta‐Solin, M. (2014) · EJNMMI Research · doi:10.1186/s13550-014-0037-3 · Cited by 25

Characterization of immunologic and neuropathologic abnormalities in wasted mice.

Woloschak, G. E., Rodriguez, M., & Krco, C. J. (1987) · The Journal of Immunology · doi:10.4049/jimmunol.138.8.2493 · Cited by 25

Abnormalities in whisking behaviour are associated with lesions in brain stem nuclei in a mouse model of amyotrophic lateral sclerosis

Grant, R. A., Sharp, P. S., Kennerley, A. J., Berwick, J., Grierson, A. J., Ramesh, T., & Prescott, T. J. (2013) · Behavioural Brain Research · doi:10.1016/j.bbr.2013.11.002 · Cited by 25

Intravascular contrast agent improves magnetic resonance angiography of carotid arteries in minipigs

Lin, W., Abendschein, D. R., Çelik, A., Dolan, R. P., Lauffer, R. B., Walovitch, R. C., & Haacke, E. M. (1997) · Journal of Magnetic Resonance Imaging · doi:10.1002/jmri.1880070605 · Cited by 24

Non-invasive characterization of β-amyloid1-40 vasoactivity by functional magnetic resonance imaging in mice

Luo, F., Seifert, T. R., Edalji, R. P., Loebbert, R. W., Hradil, V. P., Harlan, J. E., Schmidt, M. U., Nimmrich, V., Cox, B. F., & Fox, G. B. (2008) · Neuroscience · doi:10.1016/j.neuroscience.2008.04.021 · Cited by 23

Cuprizone Model as a Tool for Preclinical Studies of the Efficacy of Multiple Sclerosis Diagnosis and Therapy

Abakumova, T. O., Kuzkina, A., Zharova, M. V., Pozdeeva, D. A., Gubskiy, I. L., Shepeleva, I. I., Antonova, O. M., Nukolova, N. V., Kekelidze, Z. I., & Chekhonin, V. P. (2015) · Bulletin of Experimental Biology and Medicine · doi:10.1007/s10517-015-2903-z · Cited by 23

Lesion of the subiculum reduces the spread of amyloid beta pathology to interconnected brain regions in a mouse model of Alzheimer’s disease

George, S., Rönnbäck, A., Gouras, G. K., Petit, G. H., Grueninger, F., Winblad, B., Graff, C., & Brundin, P. (2014) · Acta Neuropathologica Communications · doi:10.1186/2051-5960-2-17 · Cited by 23

In Vivo Magnetic Resonance Imaging of Amyloid-β Plaques in Mice

Wadghiri, Y. Z., Hoang, D. M., Wısnıewskı, T., & Sigurdsson, E. M. (2012) · Methods in molecular biology · doi:10.1007/978-1-61779-551-0_30 · Cited by 22

Early impairment in a water-finding test in a longitudinal study of the Tg2576 mouse model of Alzheimer's disease

Kishimoto, Y., Higashihara, E., Fukuta, A., Nagao, A., & Kirino, Y. (2012) · Brain Research · doi:10.1016/j.brainres.2012.10.066 · Cited by 21

Altered Hippocampal Synaptic Physiology in Aged Parkin-Deficient Mice

Hanson, J. E., Orr, A., & Madison, D. V. (2010) · NeuroMolecular Medicine · doi:10.1007/s12017-010-8113-y · Cited by 21

Implementation of a manual for working with wobbler mice and criteria for discontinuation of the experiment

Ott, B., Dahlke, C., Meller, K., Napirei, M., Schmitt‐John, T., Brand‐Saberi, B., Theiß, C., & Saberi, D. (2015) · Annals of Anatomy - Anatomischer Anzeiger · doi:10.1016/j.aanat.2015.03.007 · Cited by 21

Ligation of the Jugular Veins Does Not Result in Brain Inflammation or Demyelination in Mice

Atkinson, W. L., Forghani, R., Wojtkiewicz, G. R., Pulli, B., Iwamoto, Y., Ueno, T., Waterman, P. R., Truelove, J. J., Öklü, R., & Chen, J. W. (2012) · PLoS ONE · doi:10.1371/journal.pone.0033671 · Cited by 21

Clinical Testing and Spinal Cord Removal in a Mouse Model for Amyotrophic Lateral Sclerosis (ALS)

Günther, R., Suhr, M., Koch, J. C., Bähr, M., Lingor, P., & Tönges, L. (2012) · Journal of Visualized Experiments · doi:10.3791/3936 · Cited by 21

Positron Emission Tomography Imaging of Fibrillar Parenchymal and Vascular Amyloid-β in TgCRND8 Mice

McLean, D., Cooke, M. J., Albay, R., Glabe, C. G., & Shoichet, M. S. (2013) · ACS Chemical Neuroscience · doi:10.1021/cn300226q · Cited by 21

Angiogenesis is Regulated by Angiopoietins During Experimental Autoimmune Encephalomyelitis and is Indirectly Related to Vascular Permeability

MacMillan, C. J., Starkey, R. J., & Easton, A. S. (2011) · Journal of Neuropathology & Experimental Neurology · doi:10.1097/nen.0b013e31823a8b6a · Cited by 21

NMDA Receptors and Huntington’s Disease

Fernandes, H. B., & Raymond, L. A. (2008) · Frontiers in neuroscience · doi:10.1201/9781420044157.ch2 · Cited by 21

Construction and Evaluation of Quantitative Small-Animal PET Probabilistic Atlases for [18F]FDG and [18F]FECT Functional Mapping of the Mouse Brain

Casteels, C., Vunckx, K., Aelvoet, S., Baekelandt, V., Bormans, G. M., Laere, K. V., & Koole, M. J. B. (2013) · PLoS ONE · doi:10.1371/journal.pone.0065286 · Cited by 20

Impairments in Neurogenesis Are Not Tightly Linked to Depressive Behavior in a Transgenic Mouse Model of Alzheimer's Disease

Iascone, D. M., Padidam, S., Pyfer, M. S., Zhang, X., Zhao, L., & Chin, J. (2013) · PLoS ONE · doi:10.1371/journal.pone.0079651 · Cited by 20

Quantitative activation-induced manganese-enhanced MRI reveals severity of Parkinson’s disease in mice

Kikuta, S., Nakamura, Y., Yamamura, Y., Tamura, A., Homma, N., Yanagawa, Y., Tamura, H., Kasahara, J., & Osanai, M. (2015) · Scientific Reports · doi:10.1038/srep12800 · Cited by 20

In vivo detection of amyloid plaques by gadolinium-stained MRI can be used to demonstrate the efficacy of an anti-amyloid immunotherapy.

Santin, M. D., Vandenberghe, M. E., Herard, A.-S., Pradier, L., Cohen, C., Debeir, T., Delzescaux, T., Rooney, T., & Dhenain, M. (2016) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2016.00055 · Cited by 20

Moving toward a gene therapy for Huntington’s disease

Glorioso, J. C., Cohen, J. B., Carlisle, D. L., Munoz-Sanjuan, I., & Friedlander, R. M. (2015) · Gene Therapy · doi:10.1038/gt.2015.102 · Cited by 20

PET Imaging a MPTP-Induced Mouse Model of Parkinson’s Disease Using the Fluoropropyl-Dihydrotetrabenazine Analog [18F]-DTBZ (AV-133)

Toomey, J. S., Bhatia, S., Moon, L. T., Orchard, E. A., Tainter, K. H., Lokitz, S. J., Terry, T., Mathis, J. M., & Penman, A. D. (2012) · PLoS ONE · doi:10.1371/journal.pone.0039041 · Cited by 19

Erratum to: Cuprizone Model as a Tool for Preclinical Studies of the Effi cacy of Multiple Sclerosis Diagnosis and Therapy

Abakumova, T. O., Kuzkina, A., Zharova, M. E., Pozdeeva, D. A., Gubskiy, I. L., Shepeleva, I. I., Antonova, O. M., Nukolova, N. V., Kekelidze, Z. I., & Chekhonin, V. P. (2015) · Bulletin of Experimental Biology and Medicine · doi:10.1007/s10517-015-2976-8 · Cited by 18

Noninvasive Quantification of Metabotropic Glutamate Receptor Type 1 with [ 11 C]ITDM: a Small-Animal PET Study

Yamasaki, T., Fujinaga, M., Yui, J., Ikoma, Y., Hatori, A., Xie, L., Wakizaka, H., Kumata, K., Nengaki, N., Kawamura, K., et al. (2014) · Journal of Cerebral Blood Flow & Metabolism · doi:10.1038/jcbfm.2013.243 · Cited by 18

A novel behavioral method to detect motoneuron disease in Wobbler mice aged three to seven days old

Bose, P., Fielding, R., Ameis, K., & Vacca-Galloway, L. L. (1998) · Brain Research · doi:10.1016/s0006-8993(98)01033-6 · Cited by 17

The Emerging Use ofIn VivoOptical Imaging in the Study of Neurodegenerative Diseases

Patterson, A. P., Booth, S. A., & Saba, R. (2014) · BioMed Research International · doi:10.1155/2014/401306 · Cited by 17

Correlation of Brain Atrophy, Disability, and Spinal Cord Atrophy in a Murine Model of Multiple Sclerosis

Soldán, M. M. P., Raman, M. R., Gamez, J. D., Lohrey, A. K., Chen, Y., Pirko, I., & Johnson, A. J. (2015) · Journal of Neuroimaging · doi:10.1111/jon.12250 · Cited by 17

Neonatal Iron Supplementation Induces Striatal Atrophy in Female YAC128 Huntington’s Disease Mice

Berggren, K. L., Lu, Z., Fox, J. A., Dudenhoeffer, M., Agrawal, S., & Fox, J. H. (2016) · Journal of Huntington s Disease · doi:10.3233/jhd-150182 · Cited by 16

Serial in vivo imaging of transplanted allogeneic neural stem cell survival in a mouse model of amyotrophic lateral sclerosis

Srivastava, A. K., Gross, S. K., Almad, A. A., Bulte, C. A., Maragakis, N. J., & Bulte, J. W. M. (2016) · Experimental Neurology · doi:10.1016/j.expneurol.2016.12.011 · Cited by 16

Endogenous murine Aβ increases amyloid deposition in APP23 but not in APPPS1 transgenic mice

Mahler, J., Morales‐Corraliza, J., Stolz, J., Skodras, A., Radde, R., Duma, C. C., Eisele, Y. S., Mazzella, M. J., Wong, H. K. A., Klunk, W. E., et al. (2015) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2015.03.011 · Cited by 15

Circadian Dysfunction in Response to in Vivo Treatment with the Mitochondrial Toxin 3-Nitropropionic Acid

Kudo, T., Loh, D. H., Tahara, Y., Truong, D. A., Hernández, E., & Colwell, C. S. (2013) · ASN NEURO · doi:10.1042/an20130042 · Cited by 15

Two-Point Magnitude MRI for Rapid Mapping of Brown Adipose Tissue and Its Application to the R6/2 Mouse Model of Huntington Disease

Lindenberg, K. S., Weydt, P., Müller, H., Bornstedt, A., Ludolph, A. C., Landwehrmeyer, G. B., Rottbauer, W., Kassubek, J., & Rasche, V. (2014) · PLoS ONE · doi:10.1371/journal.pone.0105556 · Cited by 15

Late onset vascular dysfunction in the R6/1 model of Huntington’s disease

Rahman, A., Ekman, M., Shakirova, Y., Andersson, K. E., Mörgelin, M., Erjefalt, J. S., Brundin, P., Li, J., & Swärd, K. (2012) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2012.10.026 · Cited by 14

Alterations of striatal glutamate transmission in rotenone-treated mice: MRI/MRS in vivo studies

Moussa, C., Rusnak, M., Hailu, A., Sidhu, A., & Fricke, S. T. (2007) · Experimental Neurology · doi:10.1016/j.expneurol.2007.09.023 · Cited by 14

High-Resolution Diffusion Tensor Spinal Cord MRI Measures as Biomarkers of Disability Progression in a Rodent Model of Progressive Multiple Sclerosis

Gilli, F., Chen, X., Pachner, A. R., & Gimi, B. (2016) · PLoS ONE · doi:10.1371/journal.pone.0160071 · Cited by 14

The role of SPECT imaging of the dopaminergic system in translational research on Parkinson's disease

Suwijn, S. R., de Bruin, K. M., de Bie, R. M. A., & Booij, J. (2013) · Parkinsonism & Related Disorders · doi:10.1016/s1353-8020(13)70043-9 · Cited by 13

Detecting Deoxyhemoglobin in Spinal Cord Vasculature of the Experimental Autoimmune Encephalomyelitis Mouse Model of Multiple Sclerosis Using Susceptibility MRI and Hyperoxygenation

Nathoo, N., Rogers, J. A., Yong, V. W., & Dunn, J. F. (2015) · PLoS ONE · doi:10.1371/journal.pone.0127033 · Cited by 12

Decreased Myelinated Fibers in the Hippocampal Dentate Gyrus of the Tg2576 Mouse Model of Alzheimer's Disease

Lü, W., Shu, Y., Zhang, L., Chen, L., Chao, F., Luo, Y., Xiao, Q., Gu, H., Jiang, R., & Tang, Y. C. (2016) · Current Alzheimer Research · doi:10.2174/1567205013666160314150709 · Cited by 12

Original Research: Feasibility and safety of two surgical techniques for the development of an animal model of jugular vein occlusion

Auletta, L., Greco, A., Albanese, S., Meomartino, L., Salvatore, M., & Mancini, M. (2016) · Experimental Biology and Medicine · doi:10.1177/1535370216657446 · Cited by 12

Molecular Imaging of PDE10A Knockout Mice with a Novel PET Radiotracer: [11C]T-773

Tóth, M., Häggkvist, J., Stepanov, V. A., Takano, A., Nakao, R., Amini, N., Miura, S., Kimura, H., Taniguchi, T., Gulyás, B. Z., et al. (2015) · Molecular Imaging and Biology · doi:10.1007/s11307-015-0822-z · Cited by 12

Autophagic induction of amyotrophic lateral sclerosislinked Cu/Zn superoxide dismutase 1 G93A mutant in NSC34 cells

Wei, Y. (2014) · Neural Regeneration Research · doi:10.4103/1673-5374.125325 · Cited by 12

Intraendosomal flow cytometry: A novel approach to analyze the protein composition of antigen‐loaded endosomes

Zehner, M., Rauen, J., Chasan, A. I., Embgenbroich, M., Camps, M. G. M., Kaden, S., Haas, A., Kurts, C., Endl, E., Beyer, M., et al. (2012) · European Journal of Immunology · doi:10.1002/eji.201142089 · Cited by 11

Deficits in hippocampal‐dependent transfer generalization learning accompany synaptic dysfunction in a mouse model of amyloidosis

Montgomery, K. S., Edwards, G. A., Levites, Y., Kumar, A., Myers, C. E., Gluck, M. A., Setlow, B., & Bizon, J. L. (2015) · Hippocampus · doi:10.1002/hipo.22535 · Cited by 10

Molecular Imaging of Cell Death in an Experimental Model of Parkinson’s Disease with a Novel Apoptosis-Targeting Peptide

Lee, M. J., Wang, K., Kim, I.-S., Lee, B.-H., & Han, H. S. (2011) · Molecular Imaging and Biology · doi:10.1007/s11307-011-0497-z · Cited by 10

A constraint-based modelling approach to metabolic dysfunction in Parkinson's disease

Mao, L., Nicolae, A., Oliveira, M. A. P., HeFeng, F. Q., Hachi, S., & Fleming, R. M. T. (2015) · Computational and Structural Biotechnology Journal · doi:10.1016/j.csbj.2015.08.002 · Cited by 9

Cerebrovascular contributions to Alzheimer's disease pathophysiology and potential therapeutic interventions in mouse models

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