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Short- and Mid-term Changes in Bone Mineral Density After Laparoscopic Sleeve Gastrectomy
Abstract
Background Bariatric surgery is the most effective treatment for achieving a significant weight loss. Morbidities present a significant reduction after bariatric surgery, but it may also result in several health complications, related to nutritional deficiencies, including bone metabolism. Several studies have reported a decrease in bone mineral density (BMD), but most of them referring to malabsorptive procedures. Restrictive procedures do not imply changes in gastrointestinal anatomy, so that one may expect fewer metabolic disturbances.Methods We performed a retrospective observational study of all morbidly obese patients undergoing LSG between 2008 and 2011 at our institution. Bone densitometry was performed before surgery and 1 and 2 years after the intervention. Body size measurements, analytical variables and densitometric values in the lumbar spine (BMD, t score and z score) were investigated.Results Forty-two patients were included, 39 females and 3 males. Mean BMI was 51.21 kg/m(2). Mean excessive BMI loss was 79.9 % after 1 year and 80.6 % after 2 years. Mean BMD values for spine increased progressively, reaching statistical significance at 1 and at 2 years. Percentage of BMD increase was 5.7 % at 1 year and 7.9 % at 2 years. An inverse correlation was observed between BMD increase and parathyroid hormone (PTH) decrease and a direct correlation between BMD and vitamin D increase.Conclusion Bone mineral density showed a progressive increase during the first and second year after sleeve gastrectomy. BMD changes are not associated with weight loss, but showed a direct correlation with vitamin D and an inverse correlation with PTH levels.
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Sleeve gastrectomy produces weight loss between that of purely restrictive and malabsorptive procedures.
“Sleeve gastrectomy is becoming increasingly common, with weight loss falling between the purely restrictive and malabsorptive procedures (1 to 2 year weight loss: 20-30%; excess BMI loss: 45-80%).36, 46-50.”
From Bone loss after bariatric surgery: causes, consequences, and management (2014) · cites this paper as [49]
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Bone loss after bariatric surgery: causes, consequences, and management
Stein, E. M., & Silverberg, S. J. (2014) · The Lancet Diabetes & Endocrinology · doi:10.1016/s2213-8587(13)70183-9 · Cited by 199
Metadata
- Authors
- Ruiz-Tovar, J., Oller, I., Priego, P., Arroyo, A., Calero, A., Diez, M., Zubiaga, L., & Calpena, R.
- Affiliations
- Universitat de Miguel Hernández d'Elx (ES)
- ORCID
- Zubiaga, Lorea
- Venue
- Obesity Surgery
- Published
- 2013-01-14
- Volume
- 23
- Issue
- 7
- Pages
- 861-866
- ISSN
- 0960-8923 (ISSN-L)
- 1708-0428
- OpenAlex
- W2162215100
- Cited by
- 78
- References
- 30
- Citations by year
- 2025: 1 · 2024: 2 · 2023: 4 · 2022: 6 · 2021: 9 · 2020: 13 · 2019: 6 · 2018: 11 · 2017: 7 · 2016: 3 · 2015: 5 · 2014: 10 · 2013: 1
- FWCI
- 6.23
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- www.springer.com/tdm (tdm)
- Locations
- Obesity Surgery (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Surgery › Bariatric Surgery and Outcomes
- Health Sciences › Medicine › Orthopedics and Sports Medicine › Bone health and osteoporosis research
- Health Sciences › Medicine › Surgery › Body Contouring and Surgery
- Keywords
- laparoscopic sleeve gastrectomy, bone mineral density
- MeSH terms
- Adult, Female, Follow-Up Studies, Humans, Intestinal Absorption, Lumbar Vertebrae, Male, Middle Aged, Nutritional Status, Obesity, Morbid, Parathyroid Hormone, Laparoscopy, Retrospective Studies, Spain, Time Factors, Vitamin D, Gastroplasty, Weight Loss, Absorptiometry, Photon, Bone Density, Body Mass Index, Treatment Outcome, Malnutrition
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