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Cited by 43Essential Oils and Antimicrobial ActivityAgricultural and Biological ResearchPlant biochemistry and biosynthesis

Factors that influence the extraction methods of terpenes from natural sources

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González-Hernández, Ricardo A., Valdez-Cruz, Norma A., Trujillo-Roldán, Mauricio A.·2024·Chemical Papers
DOI 10.1007/s11696-024-03339-z
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Abstract

Due to their various applications, terpenes and terpenoids are secondary metabolites of industrial interest. These compounds can be found in a wide variety of organisms from virtually all biological kingdoms. However, it has been identified that various factors in the production process, such as the place and time of harvest, pretreatments, extraction, and purification, generate differences in the profile of terpenes and terpenoids that can be obtained from organisms. The first factor that influences the extraction of compounds is drying since an inappropriate choice of the drying method can lead to the loss of the compounds of interest or the appearance of others that arise due to the decomposition of the original molecules. Similarly, Soxhlet extraction is the most used method in the recovery of terpenoids due to its high extraction efficiency. However, unconventional extraction methods have proven to be effective alternatives for terpenoid recovery, particularly the use of microwave and high-pressure extraction, as well as the use of unconventional solvents, achieving extraction efficiencies equal to or greater than Soxhlet in shorter times. This review will address the differences observed in the extraction of terpenoids and the main factors that cause them, as well as a comparison of the advantages and disadvantages of the various methodologies for drying, extraction, and separation of these compounds.

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  • For MAE-assisted extractions in hydroethanolic systems, it is essential to evaluate the effect of pH, extraction time, and voltage of the equipment used during extraction.

    “For MAE-assisted extractions in hydroethanolic systems, it is essential to evaluate the effect of pH, extraction time, and voltage of the equipment used during extraction [36,37]”

    From Optimized microwave-assisted azadirachtin extraction using response surface methodology (2024) · cites this paper as [36]

    The Microwave-assisted extraction (MAE) section recommends optimizing power, temperature, and time, and discusses MAE using aqueous ethanol. It does not recommend evaluating pH or equipment voltage for hydroethanolic MAE: its discussion of pH concerns liquid-liquid extraction, while electrical potential concerns pulsed electric fields. Page numbers were not available in our copy. (LLM, conf=0.87)

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Cited by

Sorted by citations

Authors
González-Hernández, R. A., Valdez-Cruz, N. A., & Trujillo-Roldán, M. A.
Affiliations
Instituto de Investigaciones Biomédicas, Universidad Nacional Autónoma de México (MX)
Corresponding author
González-Hernández, Ricardo A.
ORCID
Venue
Chemical Papers
Publisher
Springer Science and Business Media LLC
Published
2024-02-19
Volume
78
Issue
5
Pages
2783-2810
ISSN
  • 0366-6352 (ISSN-L)
  • 2585-7290
DOI
10.1007/s11696-024-03339-z
OpenAlex
W4391947347
Cited by
43
References
6
Citations by year
2026: 14 · 2025: 20 · 2024: 9
FWCI
9.27
Type
journal article
Language
en
Open access
Licence
Locations
Chemical Papers (publishedVersion, cc-by)
Funders
  • Consejo Nacional de Ciencia y Tecnología (717832, CF-2023-I-1248, CF-2023-I-1549)
  • Posgrado en Ciencias Biológicas, Universidad Nacional Autónoma de México (305115298)
  • Dirección General de Asuntos del Personal Académico, Universidad Nacional Autónoma de México (IN210822, IN211422, IV201220)
Topics
  • Life Sciences › Agricultural and Biological Sciences › Food Science › Essential Oils and Antimicrobial Activity
  • Life Sciences › Agricultural and Biological Sciences › Food Science › Agricultural and Biological Research
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Plant biochemistry and biosynthesis
Keywords
terpenes, terpenoids, extraction methods, drying methods, Soxhlet extraction, microwave-assisted extraction, high-pressure extraction, secondary metabolites, harvest time, sample preparation, extraction efficiency

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