Cited by 407Phytochemicals and Antioxidant ActivitiesAgricultural and Biological ResearchEdible Oils Quality and Analysis

Recent advances and comparisons of conventional and alternative extraction techniques of phenolic compounds

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Osorio-Tobón, J. Felipe·2020·Journal of Food Science and Technology

Abstract

Phenolic compounds are a group of secondary metabolites produced by plants under stressful conditions. Phenolic compounds play an important role in the prevention and treatment of certain illnesses and are exploited by the food and pharmaceutical industries. Conventional methods are commonly used as models to compare the efficiencies of alternative extraction methods. Among alternative extraction processes, microwave-assisted extraction (MAE), pressurized liquid extraction (PLE), supercritical fluid extraction (SFE) and ultrasonic-assisted extraction (UAE) are the most studied. These methods produce extracts rich in phenolic compounds using moderate temperatures, short extraction times, and solvents generally recognized as safe. The combination of extraction time and temperature plays a critical role in the stability of the compounds. Solvents of higher polarity enhance the extraction of phenolic compounds. The use of the ethanol-water mixture for MAE, PLE, and UAE is recommended. MAE and UAE involve shorter extraction times than do PLE and SFE. SFE requires a low average temperature (40 °C). MAE produces the highest total phenolic content [227.63 mg GAE/g dry basis (d.b.)], followed by PLE (173.65 mg GAE/g d.b.), UAE (92.99 mg GAE/g d.b.) and SFE (37 mg GAE/g d.b.). Extraction yields and recovery rates of the phenolic compounds can be enhanced by combining and integrating extraction methods.

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Authors
Osorio-Tobón, J. F.
Affiliations
Institución Universitaria Colegio Mayor de Antioquia (CO)
Corresponding author
Osorio-Tobón, J. Felipe
Venue
Journal of Food Science and Technology
Published
2020-05-28
Volume
57
Issue
12
Pages
4299-4315
ISSN
  • 0022-1155 (ISSN-L)
  • 0975-8402
OpenAlex
W3029959204
Cited by
407
References
80
Citations by year
2026: 96 · 2025: 113 · 2024: 76 · 2023: 53 · 2022: 37 · 2021: 30 · 2020: 2
FWCI
2.65
Type
journal article
Language
en
Open access
Locations
  • Journal of Food Science and Technology (publishedVersion)
  • PubMed Central (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Biochemistry › Phytochemicals and Antioxidant Activities
  • Life Sciences › Agricultural and Biological Sciences › Food Science › Agricultural and Biological Research
  • Physical Sciences › Chemistry › Organic Chemistry › Edible Oils Quality and Analysis
Keywords
phenolic compounds, extraction methods, microwave-assisted extraction, accelerated solvent extraction, supercritical fluid extraction, ultrasound-assisted extraction, ethanol-water solvent, extraction temperature and time, total phenolic content, extraction yield, plant secondary metabolites

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