The DOI matches its Crossref record; 10 of the 10 references it cites were found in a registry or an index.
Environmental Chemicals and Type 2 Diabetes: An Updated Systematic Review of the Epidemiologic Evidence
Open accessAbstract
The burden of diabetes is increasing globally. Identifying novel preventable risk factors is an urgent need. In 2011, the U.S. National Toxicological Program (NTP) conducted a workshop to evaluate the epidemiologic and experimental evidence on the relationship of environmental chemicals with obesity, diabetes, and metabolic syndrome. Although the evidence was insufficient to establish causality, the NTP workshop review identified an overall positive association between some environmental chemicals and diabetes. In the present systematic review, our objective was to summarize the epidemiological research published since the NTP workshop. We identified a total of 29 articles (7 on arsenic, 3 on cadmium, 2 on mercury, 11 on persistent organic pollutants, 3 on phthalates, and 4 on bisphenol A), including 7 prospective studies. Considering consistency, temporality, strength, dose–response relationship, and biological plausibility (confounding), we concluded that the evidence is suggestive but not sufficient for a relationship between arsenic and persistent organic pollutants and is insufficient for mercury, phthalates, and bisphenol A. For cadmium, the epidemiologic evidence does not seem to suggest an association with diabetes. Important research questions include the need for additional prospective studies and the evaluation of the dose–response relationship, the role of joint exposures, and effect modification with other comorbidities and genetic variants.
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Cites
Preferred reporting items for systematic reviews and meta-analyses: The PRISMA statement
Moher, D., Liberati, A., Tetzlaff, J., Altman, D. G., & the PRISMA Group* (2009) · Annals of Internal Medicine · doi:10.7326/0003-4819-151-4-200908180-00135 · Cited by 37,554
Standards of medical care in diabetes—2013
American Diabetes Association (2013) · Diabetes Care · doi:10.2337/dc13-s011 · Cited by 4,369
DeFronzo, R. A., Ferrannini, E., Groop, L., Henry, R. R., Herman, W. H., Holst, J. J., Hu, F. B., Kahn, C. R., Raz, I., Shulman, G. I., et al. (2015) · Nature Reviews Disease Primers · doi:10.1038/nrdp.2015.19 · Cited by 2,611
Exposure of the U.S. Population to Bisphenol A and 4- tertiary -Octylphenol: 2003–2004
Calafat, A. M., Ye, X., Wong, L.-Y., Reidy, J. A., & Needham, L. L. (2008) · Environmental Health Perspectives · doi:10.1289/ehp.10753 · Cited by 1,743
Active Smoking and the Risk of Type 2 Diabetes: A Systematic Review and Meta-analysis
Willi, C., Bodenmann, P., Ghali, W. A., Faris, P. D., & Cornuz, J. (2007) · JAMA · doi:10.1001/jama.298.22.2654 · Cited by 1,268
Exposure to Bisphenol A and Other Phenols in Neonatal Intensive Care Unit Premature Infants
Calafat, A. M., Weuve, J., Ye, X., Jia, L. T., Hu, H., Ringer, S., Huttner, K., & Hauser, R. (2009) · Environmental Health Perspectives · doi:10.1289/ehp.0800265 · Cited by 374 · cited 1×
“Dietary exposure to BPA-contaminated food and beverages likely represents the major source of exposure for general populations [106], although it is clear that we do not understand all the sources of exposure to BPA, as evidenced by findings in medical devices [107] and thermal paper [108].”
Variability and predictors of urinary bisphenol A concentrations during pregnancy
Braun, J. M., Kalkbrenner, A. E., Calafat, A. M., Bernert, J. T., Ye, X., Silva, M. J., Barr, D. B., Sathyanarayana, S., & Lanphear, B. P. (2011) · Environmental Health Perspectives · doi:10.1289/ehp.1002366 · Cited by 352
Navas-Acien, A., Silbergeld, E. K., Streeter, R. A., Clark, J. M., Burke, T. A., & Guallar, E. (2006) · Environmental Health Perspectives · doi:10.1289/ehp.8551 · Cited by 339
Porta, M., Puigdomènech, E., Ballester, F., Selva, J., Ribas-Fitó, N., Llop, S., & López, T. (2008) · Environment International · doi:10.1016/j.envint.2007.10.004 · Cited by 200
Douillet, C., Currier, J., Saunders, J., Bodnar, W. M., Matoušek, T., & Stýblo, M. (2013) · Toxicology and Applied Pharmacology · doi:10.1016/j.taap.2012.12.007 · Cited by 104
Cited by
EDC-2: the endocrine society's second scientific statement on endocrine-disrupting chemicals
Gore, A. C., Chappell, V. A., Fenton, S. E., Flaws, J. A., Nadal, A., Prins, G. S., Toppari, J., & Zoeller, R. T. (2015) · Endocrine Reviews · doi:10.1210/er.2015-1010 · Cited by 2,407
Social determinants of health and diabetes: A scientific review
Hill-Briggs, F., Adler, N. E., Berkowitz, S. A., Chin, M. H., Gary-Webb, T. L., Navas-Acien, A., Thornton, P. L., & Haire-Joshu, D. (2021) · Diabetes Care · doi:10.2337/dci20-0053 · Cited by 1,732
A Review of Biomonitoring of Phthalate Exposures
Wang, Y., Zhu, H., & Kannan, K. (2019) · Toxics · doi:10.3390/toxics7020021 · Cited by 755
Phthalates impact human health: Epidemiological evidences and plausible mechanism of action
Benjamin, S., Masai, E., Kamimura, N., Takahashi, K., Anderson, R. C., & Faisal, P. A. (2017) · Journal of Hazardous Materials · doi:10.1016/j.jhazmat.2017.06.036 · Cited by 747
Environmental factors in cardiovascular disease
Cosselman, K. E., Navas-Acien, A., & Kaufman, J. D. (2015) · Nature Reviews Cardiology · doi:10.1038/nrcardio.2015.152 · Cited by 613
Self-citation
Metadata
- Authors
- Kuo, C.-C., Moon, K., Thayer, K. A., & Navas-Acien, A.
- Venue
- Current Diabetes Reports
- Published
- 2013-10-11
- Volume
- 13
- Issue
- 6
- Pages
- 831-849
- ISSN
- 1534-4827 (ISSN-L)
- 1539-0829
- OpenAlex
- W2037898660
- Cited by
- 274
- References
- 10
- FWCI
- 5.80
- Type
- journal article
- Language
- en
- Open access
- green
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