Exposure to Bisphenol A and Other Phenols in Neonatal Intensive Care Unit Premature Infants
Open accessAbstract
OBJECTIVE: We previously demonstrated that exposure to polyvinyl chloride plastic medical devices containing di(2-ethylhexyl) phthalate (DEHP) was associated with higher urinary concentrations of several DEHP metabolites in 54 premature infants in two neonatal intensive care units than in the general population. For 42 of these infants, we evaluated urinary concentrations of several phenols, including bisphenol A (BPA), in association with the use of the same medical devices. MEASUREMENTS: We measured the urinary concentrations of free and total (free plus conjugated) species of BPA, triclosan, benzophenone-3, methyl paraben, and propyl paraben. RESULTS: The percentage of BPA present as its conjugated species was > 90% in more than three-quarters of the premature infants. Intensity of use of products containing DEHP was strongly associated with BPA total concentrations but not with any other phenol. Adjusting for institution and sex, BPA total concentrations among infants in the group of high use of DEHP-containing products were 8.75 times as high as among infants in the low use group (p < 0.0001). Similarly, after adjusting for sex and DEHP-containing product use category, BPA total concentrations among infants in Institution A were 16.6 times as high as those among infants in Institution B (p < 0.0001). CONCLUSION: BPA geometric mean urinary concentration (30.3 microg/L) among premature infants undergoing intensive therapeutic medical interventions was one order of magnitude higher than that among the general population. Conjugated species were the primary urinary metabolites of BPA, suggesting that premature infants have some capacity to metabolize BPA. The differences in exposure to BPA by intensity of use of DEHP-containing medical products highlight the need for further studies to determine the specific source(s) of exposure to BPA.
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Neonates who receive medical treatments such as transfusions are widely recognized as potentially highly exposed.
“Neonates who receive medical treatments such as transfusions are widely recognized as potentially highlexposed [148].”
From A Review of Biomonitoring of Phthalate Exposures (2019) · cites this paper as [148]
The Conclusion describes premature infants receiving intensive medical treatment as a potential high-risk population for chemical exposure, and the Discussion reports elevated BPA exposure associated with greater use of medical products. The paper does not identify transfusions as an example or assess exposure from them, so that specific part of the claim is unsupported. (LLM, conf=0.84)
Experimental — accuracy not yet measured
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Cites
Estimation of Average Concentration in the Presence of Nondetectable Values
Hornung, R. W., & Reed, L. D. (1990) · Applied Occupational and Environmental Hygiene · doi:10.1080/1047322x.1990.10389587 · Cited by 3,495 · see citing works
Human exposure to bisphenol A (BPA)
Vandenberg, L. N., Hauser, R. B., Marcus, M., Olea, N., & Welshons, W. V. (2007) · Reproductive Toxicology · doi:10.1016/j.reprotox.2007.07.010 · Cited by 2,897 · see citing works
Self-citationExposure of the U.S. Population to Bisphenol A and 4- <i>tertiary</i> -Octylphenol: 2003–2004
Calafat, A. M., Ye, X., Wong, L.-Y., Reidy, J. A., & Needham, L. L. (2008) · Environmental Health Perspectives · doi:10.1289/ehp.10753 · Cited by 1,743 · see citing works
Self-citationSaal, F. S. V., & Hughes, C. L. (2005) · Environmental Health Perspectives · doi:10.1289/ehp.7713 · Cited by 1,174 · see citing works
Kang, J., Kondo, F., & Katayama, Y. (2006) · Toxicology · doi:10.1016/j.tox.2006.06.009 · Cited by 878 · see citing works
In Vitro and in Vivo Estrogenicity of UV Screens
Schlumpf, M., Cotton, B., Conscience-Egli, M., Haller, V., Steinmann, B., & LICHTENSTEIGER, W. (2001) · Environmental Health Perspectives · doi:10.1289/ehp.01109239 · Cited by 847 · see citing works
Exposure to bisphenol A advances puberty
Howdeshell, K. L., Hotchkiss, A. K., Thayer, K. A., Vandenbergh, J. G., & vom Saal, F. S. (1999) · Nature · doi:10.1038/44517 · Cited by 820 · see citing works
Ho, S.-M., Tang, W.-Y., Belmonte de Frausto, J., & Prins, G. S. (2006) · Cancer Research · doi:10.1158/0008-5472.can-06-0516 · Cited by 796 · see citing works
Darbre, P. D., & Harvey, P. W. (2008) · Journal of Applied Toxicology · doi:10.1002/jat.1358 · Cited by 702 · see citing works
Quality assurance of chemical measurements
Taylor, J. K., & Tranter, R. L. (1989) · Analytica Chimica Acta · doi:10.1016/s0003-2670(00)80373-6 · Cited by 690 · see citing works
Urinary Concentrations of Triclosan in the U.S. Population: 2003–2004
Calafat, A. M., Ye, X., Wong, L.-Y., Reidy, J. A., & Needham, L. L. (2007) · Environmental Health Perspectives · doi:10.1289/ehp.10768 · Cited by 553 · see citing works
Self-citationQuality Assurance of Chemical Measurements
Lodge, J. P. (1988) · Atmospheric Environment (1967) · doi:10.1016/0004-6981(88)90464-7 · Cited by 518 · see citing works
NTP‐CERHR expert panel report on the reproductive and developmental toxicity of bisphenol A
Chapin, R. E., Adams, J., Boekelheide, K., Gray, L. E., Hayward, S. W., Lees, P. S. J., Mcintyre, B., Portier, K. M., Schnorr, T. M., Selevan, S. G., et al. (2008) · Birth Defects Research Part B Developmental and Reproductive Toxicology · doi:10.1002/bdrb.20147 · Cited by 504 · see citing works
Triclosan: A review of effectiveness and safety in health care settings
Jones, R. D., Jampani, H. B., Newman, J. L., & Lee, A. S. (2000) · American Journal of Infection Control · doi:10.1067/mic.2000.102378 · Cited by 487 · see citing works
Ye, X., Kuklenyik, Z., Needham, L. L., & Calafat, A. M. (2005) · Analytical Chemistry · doi:10.1021/ac050390d · Cited by 412 · see citing works
Self-citationTimms, B. G., Howdeshell, K. L., Barton, L., Bradley, S., Richter, C. A., & vom Saal, F. S. (2005) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0502544102 · Cited by 394 · see citing works
de Wildt, S. N., KEARNS, G., Leeder, J. S., & van den Anker, J. N. (1999) · Clinical Pharmacokinetics · doi:10.2165/00003088-199936060-00005 · Cited by 392 · see citing works
Calafat, A., Wong, L.-Y., Ye, X.-Y., Reidy, J., & Needham, L. (2008) · Environmental Health Perspectives · doi:10.1289/ehp.11269 · Cited by 389 · see citing works
Self-citationMurray, T. J., Maffini, M. V., Ucci, A. A., Sonnenschein, C., & Soto, A. M. (2006) · Reproductive Toxicology · doi:10.1016/j.reprotox.2006.10.002 · Cited by 323 · see citing works
Prenatal Bisphenol A Exposure Induces Preneoplastic Lesions in the Mammary Gland in Wistar Rats
Durando, M., Kass, L., Piva, J., Sonnenschein, C., Soto, A. M., Luque, E. H., & Muñoz‐de‐Toro, M. (2006) · Environmental Health Perspectives · doi:10.1289/ehp.9282 · Cited by 323 · see citing works
Parabens as Urinary Biomarkers of Exposure in Humans
Ye, X., Bishop, A. M., Reidy, J. A., Needham, L. L., & Calafat, A. M. (2006) · Environmental Health Perspectives · doi:10.1289/ehp.9413 · Cited by 311 · see citing works
Self-citationGreen, R., Hauser, R. B., Calafat, A. M., Weuve, J., Schettler, T., Ringer, S. A., Huttner, K. M., & Hu, H. (2005) · Environmental Health Perspectives · doi:10.1289/ehp.7932 · Cited by 270 · see citing works
Self-citationPalanza, P. L., Howdeshell, K. L., Parmigiani, S., & vom Saal, F. S. (2002) · Environmental Health Perspectives · doi:10.1289/ehp.02110s3415 · Cited by 268 · see citing works
Exposure to Di-(2-Ethylhexyl) Phthalate Among Premature Neonates in a Neonatal Intensive Care Unit
Calafat, A. M., Needham, L. L., Silva, M. J., & Lambert, G. H. (2004) · PEDIATRICS · doi:10.1542/peds.113.5.e429 · Cited by 264 · see citing works
Self-citationNTP-CERHR monograph on the potential human reproductive and developmental effects of bisphenol A.
Shelby, M. D. (2008) · PubMed · Cited by 262 · see citing works
Ontogeny of drug metabolizing enzymes in the neonate
Blake, M. J., Castro, L., Leeder, J. S., & Kearns, G. L. (2005) · Seminars in Fetal and Neonatal Medicine · doi:10.1016/j.siny.2004.11.001 · Cited by 200 · see citing works
Developmental exposure to environmental estrogens alters anxiety and spatial memory in female mice
Ryan, B. C., & Vandenbergh, J. G. (2006) · Hormones and Behavior · doi:10.1016/j.yhbeh.2006.01.007 · Cited by 180 · see citing works
Gonzalez, H., Farbrot, A., Larkö, O., & Wennberg, A.-M. (2005) · British Journal of Dermatology · doi:10.1111/j.1365-2133.2005.07007.x · Cited by 174 · see citing works
Weuve, J., Sánchez, B. N., Calafat, A. M., Schettler, T., Green, R. A., Hu, H., & Hauser, R. B. (2006) · Environmental Health Perspectives · doi:10.1289/ehp.8926 · Cited by 166 · see citing works
Self-citationGioiosa, L., Fissore, E., Ghirardelli, G., Parmigiani, S., & Palanza, P. (2007) · Hormones and Behavior · doi:10.1016/j.yhbeh.2007.05.006 · Cited by 160 · see citing works
Parabens: A Review of Epidemiology, Structure, Allergenicity, and Hormonal Properties
Cashman, A. L., & Warshaw, E. M. (2005) · Dermatitis · doi:10.1097/01206501-200506000-00001 · Cited by 153 · see citing works
Safety assessment of Di-(2-ethylhexyl) phthalate (DEHP) released from PVC medical devices
Fda, U. (2001) · Cited by 153 · see citing works
Ye, X., Kuklenyik, Z., BISHOP, A., Needham, L. L., & Calafat, A. M. (2006) · Journal of Chromatography B · doi:10.1016/j.jchromb.2006.06.037 · Cited by 148 · see citing works
Self-citationGoodman, J. E., McConnell, E. E., Sipes, I. G., Witorsch, R. J., Slayton, T. M., Yu, C. J., Lewis, A. S., & Rhomberg, L. R. (2006) · Critical Reviews in Toxicology · doi:10.1080/10408440600758317 · Cited by 131 · see citing works
Negishi, T., Kawasaki, K., Suzaki, S., Maeda, H., Ishii, Y., Kyuwa, S., Kuroda, Y., & Yoshikawa, Y. (2004) · Environmental Health Perspectives · doi:10.1289/ehp.6961 · Cited by 126 · see citing works
Jansen, P. L. M., Mulder, G. J., Burchell, B., & Bock, K. W. (1992) · Hepatology · doi:10.1002/hep.1840150328 · Cited by 103 · see citing works
Weight-of-Evidence Evaluation of Reproductive and Developmental Effects of Low Doses of Bisphenol A
Goodman, J. E., Witorsch, R. J., McConnell, E. E., Sipes, I. G., Slayton, T. M., Yu, C. J., Franz, A. M., & Rhomberg, L. R. (2008) · Critical Reviews in Toxicology · doi:10.1080/10408440802157839 · Cited by 102 · see citing works
Ye, X., Bishop, A. M., Reidy, J. A., Needham, L. L., & Calafat, A. M. (2007) · Journal of Exposure Science & Environmental Epidemiology · doi:10.1038/sj.jes.7500566 · Cited by 100 · see citing works
Self-citationDevelopment of multiple activities of UDP-glucuronyltransferase in human liver
Leakey, J. E. A., Hume, R., & Burchell, B. (1987) · Biochemical Journal · doi:10.1042/bj2430859 · Cited by 98 · see citing works
Development of Human Liver UDP-Glucuronosyltransferases
Burchell, B., Coughtrie, M. W. H., Jackson, M. R., Harding, D., Fournel‐Gigleux, S., Leakey, J., & Hume, R. (2017) · Developmental Pharmacology and Therapeutics · doi:10.1159/000457587 · Cited by 93 · see citing works
Weight of the Evidence Evaluation of Low-Dose Reproductive and Developmental Effects of Bisphenol A
Gray, G. M., Cohen, J. T., Cunha, G. R., Hughes, C. L., McConnell, E. E., Rhomberg, L. R., Sipes, I. G., & Mattison, D. R. (2004) · Human and Ecological Risk Assessment An International Journal · doi:10.1080/10807030490513883 · Cited by 92 · see citing works
Pubertal exposure to estrogenic chemicals affects behavior in juvenile and adult male rats
Della Seta, D., Minder, I., Belloni, V., Aloisi, A. M., Dessì-Fulgheri, F., & Farabollini, F. (2006) · Hormones and Behavior · doi:10.1016/j.yhbeh.2006.03.015 · Cited by 86 · see citing works
Weber, D. J., & Rutala, W. A. (2006) · Infection Control and Hospital Epidemiology · doi:10.1086/507964 · Cited by 82 · see citing works
Chapin, R. E., Augustine‐Rauch, K. A., Beyer, B. K., Daston, G. P., Finnell, R. H., Flynn, T. J., Hunter, S., Mirkes, P., O’Shea, K. S., Piersma, A. H., et al. (2008) · Birth Defects Research Part B Developmental and Reproductive Toxicology · doi:10.1002/bdrb.20158 · Cited by 78 · see citing works
Estrogenic chemicals at puberty change ERα in the hypothalamus of male and female rats
Ceccarelli, I., Seta, D. D., Fiorenzani, P., Farabollini, F., & Aloisi, A. M. (2006) · Neurotoxicology and Teratology · doi:10.1016/j.ntt.2006.10.011 · Cited by 70 · see citing works
Laviola, G., Gioiosa, L., Adriani, W., & Palanza, P. (2005) · Brain Research Bulletin · doi:10.1016/j.brainresbull.2004.11.015 · Cited by 54 · see citing works
Karin, A., Sharon, M., Heidi, O., Sazan, P., Grazia, P., Stefania, V., & Ana, P. P. (2010) · Joint Research Centre (European Commission) · doi:10.2788/40195 · Cited by 49 · see citing works
Flagged first, then by citations
Cited by
Sorted by citations
Plastics, the environment and human health: current consensus and future trends
Thompson, R. C., Moore, C. J., Saal, F. S. V., & Swan, S. H. (2009) · Philosophical Transactions of the Royal Society B Biological Sciences · doi:10.1098/rstb.2009.0053 · Cited by 3,068 · see citing works
Bisphenol A: An endocrine disruptor with widespread exposure and multiple effects
Rubin, B. S. (2011) · The Journal of Steroid Biochemistry and Molecular Biology · doi:10.1016/j.jsbmb.2011.05.002 · Cited by 1,420 · see citing works
Urinary, Circulating, and Tissue Biomonitoring Studies Indicate Widespread Exposure to Bisphenol A
Vandenberg, L. N., Chahoud, I., Heindel, J. J., Padmanabhan, V., Paumgartten, F. J. R., & Schönfelder, G. (2010) · Environmental Health Perspectives · doi:10.1289/ehp.0901716 · Cited by 1,232 · see citing works
Bisphenol A – Sources, toxicity and biotransformation
Michałowicz, J. (2014) · Environmental Toxicology and Pharmacology · doi:10.1016/j.etap.2014.02.003 · Cited by 1,095 · see citing works
EFSA Panel on Food Contact Materials, E. (2015) · EFSA Journal · doi:10.2903/j.efsa.2015.3978 · Cited by 1,026 · see citing works
A review of dietary and non-dietary exposure to bisphenol-A
Geens, T., Aerts, D., Berthot, C., Bourguignon, J.-P., Goeyens, L., Lecomte, P., Maghuin‐Rogister, G., Pironnet, A.-M., Pussemier, L., Scippo, M., et al. (2012) · Food and Chemical Toxicology · doi:10.1016/j.fct.2012.07.059 · Cited by 976 · see citing works
Global Assessment of Bisphenol A in the Environment
Corrales, J., Kristofco, L. A., Steele, W. B., Yates, B. S., Breed, C. S., Williams, E. S., & Brooks, B. W. (2015) · Dose-Response · doi:10.1177/1559325815598308 · Cited by 778 · see citing works
A Review of Biomonitoring of Phthalate Exposures
Wang, Y., Zhu, H., & Kannan, K. (2019) · Toxics · doi:10.3390/toxics7020021 · Cited by 755 · see citing works
Giulivo, M., de Alda, M. L., Capri, E., & Barceló, . (2016) · Environmental Research · doi:10.1016/j.envres.2016.07.011 · Cited by 577 · see citing works
A review of the carcinogenic potential of bisphenol A
Seachrist, D. D., Bonk, K. W., Ho, S., Prins, G. S., Soto, A. M., & Keri, R. A. (2015) · Reproductive Toxicology · doi:10.1016/j.reprotox.2015.09.006 · Cited by 493 · see citing works
Urinary, Circulating, and Tissue Biomonitoring Studies Indicate Widespread Exposure to Bisphenol A
Vandenberg, L. N., Chahoud, I., Heindel, J. J., Padmanabhan, V., Paumgartten, F. J. R., & Schönfelder, G. (2012) · Ciência & Saúde Coletiva · doi:10.1590/s1413-81232012000200015 · Cited by 433 · see citing works
Stahlhut, R. W., Welshons, W. V., & Swan, S. H. (2009) · Environmental Health Perspectives · doi:10.1289/ehp.0800376 · Cited by 425 · see citing works
Prenatal bisphenol A exposure and early childhood behavior.
Braun, J. M., Yolton, K., Dietrich, K. N., Hornung, R., Ye, X., Calafat, A. M., & Lanphear, B. P. (2009) · Environmental Health Perspectives · doi:10.1289/ehp.0900979 · Cited by 481 · see citing works
Self-citationYe, X., Wong, L.-Y., Kramer, J. P., Zhou, X., Jia, T., & Calafat, A. M. (2015) · Environmental Science & Technology · doi:10.1021/acs.est.5b02135 · Cited by 395 · see citing works
Self-citationWidespread Occurrence of Bisphenol A in Paper and Paper Products: Implications for Human Exposure
Liao, C., & Kannan, K. (2011) · Environmental Science & Technology · doi:10.1021/es202507f · Cited by 392 · see citing works
Molecular Mechanisms of Action of BPA
Acconcia, F., Pallottini, V., & Marino, M. (2015) · Dose-Response · doi:10.1177/1559325815610582 · Cited by 390 · see citing works
Critical evaluation of key evidence on the human health hazards of exposure to bisphenol A
Hengstler, J. G., Foth, H., Gebel, T., Kramer, P.-J., Lilienblum, W., Schweinfurth, H., Völkel, W., Wollin, K., & Gundert‐Remy, U. (2011) · Critical Reviews in Toxicology · doi:10.3109/10408444.2011.558487 · Cited by 345 · see citing works
Pharmacokinetics of bisphenol A in humans following a single oral administration
Thayer, K. A., Doerge, D. R., Hunt, D., Schurman, S. H., Twaddle, N. C., Churchwell, M. I., Garantziotis, S., Kissling, G. E., Easterling, M. R., Bucher, J. R., et al. (2015) · Environment International · doi:10.1016/j.envint.2015.06.008 · Cited by 328 · see citing works
Exposure to environmental endocrine disruptors and child development
Meeker, J. D. (2012) · Archives of Pediatrics & Adolescent Medicine · doi:10.1001/archpediatrics.2012.241 · Cited by 294 · see citing works
Lee, J., Choi, K., Park, J., Moon, H., Choi, G., Lee, J. J., Suh, E., Kim, H., Eun, S.-H., Kim, G.-H., et al. (2018) · The Science of The Total Environment · doi:10.1016/j.scitotenv.2017.10.042 · Cited by 286 · see citing works
Kuo, C.-C., Moon, K. A., Thayer, K. A., & Navas‐Acién, A. (2013) · Current Diabetes Reports · doi:10.1007/s11892-013-0432-6 · Cited by 271 · see citing works
LaKind, J. S., & Naiman, D. Q. (2010) · Journal of Exposure Science & Environmental Epidemiology · doi:10.1038/jes.2010.9 · Cited by 269 · see citing works
Health risk of exposure to Bisphenol A (BPA).
Konieczna, A., Rutkowska, A. Z., & Rachoń, D. (2015) · PubMed · Cited by 269 · see citing works
Fernandez, M. O., Bourguignon, N. S., Lux-Lantos, V. A., & Libertun, C. (2010) · Environmental Health Perspectives · doi:10.1289/ehp.0901257 · Cited by 266 · see citing works
Mustieles, V., D’Cruz, S. C., Couderq, S., Rodríguez‐Carrillo, A., Fini, J., Hofer, T., Steffensen, I., Dirven, H. A. A. M., Barouki, R., Olea, N., et al. (2020) · Environment International · doi:10.1016/j.envint.2020.105811 · Cited by 269 · see citing works
Zhou, X., Kramer, J. P., Calafat, A. M., & Ye, X. (2013) · Journal of Chromatography B · doi:10.1016/j.jchromb.2013.11.009 · Cited by 261 · see citing works
Self-citationLong-term effects of environmental endocrine disruptors on reproductive physiology and behavior
Patisaul, H. B. (2009) · Frontiers in Behavioral Neuroscience · doi:10.3389/neuro.08.010.2009 · Cited by 245 · see citing works
Urinary bisphenol A concentrations and early reproductive health outcomes among women undergoing IVF
Ehrlich, S., Williams, P. L., Missmer, S. A., Flaws, J. A., Ye, X., Calafat, A. M., Petrozza, J. C., Wright, D. L., & Hauser, R. B. (2012) · Human Reproduction · doi:10.1093/humrep/des328 · Cited by 246 · see citing works
Self-citationLi, Y., Burns, K. A., Arao, Y., Luh, C. J., & Korach, K. S. (2012) · Environmental Health Perspectives · doi:10.1289/ehp.1104689 · Cited by 234 · see citing works
Chemical recycling of poly(bisphenol A carbonate)
Kim, J. G. (2020) · Polymer Chemistry · doi:10.1039/c9py01927h · Cited by 232 · see citing works
State of the evidence 2017: an update on the connection between breast cancer and the environment
Gray, J., Rasanayagam, S., Engel, C. L., & Rizzo, J. (2017) · Environmental Health · doi:10.1186/s12940-017-0287-4 · Cited by 230 · see citing works
Song, Y., Chou, E. L., Baecker, A., You, N. Y., Song, Y., Sun, Q., & Liu, S. (2016) · Journal of Diabetes · doi:10.1111/1753-0407.12325 · Cited by 228 · see citing works
Ullah, A., Pirzada, M., Jahan, S., Ullah, H., Shaheen, G., Rehman, H., Siddiqui, M. F., & Butt, M. A. (2018) · Chemosphere · doi:10.1016/j.chemosphere.2018.06.089 · Cited by 224 · see citing works
Human Excretion of Bisphenol A: Blood, Urine, and Sweat (BUS) Study
Genuis, S. J., Beesoon, S., Birkholz, D., & Lobo, R. A. (2011) · Journal of Environmental and Public Health · doi:10.1155/2012/185731 · Cited by 216 · see citing works
Twenty-Four Hour Human Urine and Serum Profiles of Bisphenol A during High-Dietary Exposure
Teeguarden, J. G., Calafat, A. M., Ye, X., Doerge, D. R., Churchwell, M. I., Gunawan, R., & Graham, M. K. (2011) · Toxicological Sciences · doi:10.1093/toxsci/kfr160 · Cited by 215 · see citing works
Self-citationCabaton, N. J., Wadia, P. R., Rubin, B. S., Zalko, D., Schaeberle, C. M., Askenase, M. H., Gadbois, J. L., Tharp, A. P., Whitt, G. S., Sonnenschein, C., et al. (2010) · Environmental Health Perspectives · doi:10.1289/ehp.1002559 · Cited by 211 · see citing works
Gerona, R. R. L., Woodruff, T. J., Dickenson, C. A., Pan, J., Schwartz, J. M., Sen, Ś., Friesen, M. W., Fujimoto, V. Y., & Hunt, P. A. (2013) · Environmental Science & Technology · doi:10.1021/es402764d · Cited by 203 · see citing works
Zhang, Y., Ren, X., Li, Y., Yao, X., Li, C.-H., Qin, Z., & Guo, L. (2017) · Environmental Pollution · doi:10.1016/j.envpol.2017.11.027 · Cited by 202 · see citing works
Bisphenol A: Human exposure and neurobehavior
Mustieles, V., Pérez‐Lobato, R., Olea, N., & Fernández, M. F. (2015) · NeuroToxicology · doi:10.1016/j.neuro.2015.06.002 · Cited by 203 · see citing works
Adewale, H. B., Jefferson, W. N., Newbold, R. R., & Patisaul, H. B. (2009) · Biology of Reproduction · doi:10.1095/biolreprod.109.078261 · Cited by 198 · see citing works
Obesity II: Establishing causal links between chemical exposures and obesity
Heindel, J., Howard, S., Agay-Shay, K., Arrebola, J., Audouze, K., Babin, P. J., Barouki, R., Bansal, A., Blanc, E. B., Cave, M., et al. (2022) · Biochemical Pharmacology · doi:10.1016/j.bcp.2022.115015 · Cited by 173 · see citing works
Li, X., Ying, G., Zhao, J., Chen, Z., Lai, H., & Su, H. (2011) · Environment International · doi:10.1016/j.envint.2011.03.026 · Cited by 187 · see citing works
Ahmed, S., & Atlas, E. (2016) · International Journal of Obesity · doi:10.1038/ijo.2016.95 · Cited by 189 · see citing works
Bio-Based Aromatic Epoxy Monomers for Thermoset Materials
Ng, F., Couture, G., Philippe, C., Boutevin, B., & Caillol, S. (2017) · Molecules · doi:10.3390/molecules22010149 · Cited by 185 · see citing works
Bisphenol A concentrations in maternal breast milk and infant urine
Mendonca, K., Hauser, R. B., Calafat, A. M., Arbuckle, T. E., & Duty, S. M. (2012) · International Archives of Occupational and Environmental Health · doi:10.1007/s00420-012-0834-9 · Cited by 183 · see citing works
Self-citationKoch, H. M., Kolossa‐Gehring, M., Schröter‐Kermani, C., Angerer, J., & Brüning, T. (2012) · Journal of Exposure Science & Environmental Epidemiology · doi:10.1038/jes.2012.39 · Cited by 180 · see citing works
Biomass-derived chemical substitutes for bisphenol A: recent advancements in catalytic synthesis
Liguori, F., Moreno‐Marrodán, C., & Barbaro, P. (2020) · Chemical Society Reviews · doi:10.1039/d0cs00179a · Cited by 171 · see citing works
Allard, P., & Colaiácovo, M. P. (2010) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1010386107 · Cited by 170 · see citing works
Gao, X., & Wang, H. (2014) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph110808399 · Cited by 168 · see citing works
Vandenberg, L. N., Chahoud, I., Padmanabhan, V., Paumgartten, F. J. R., & Schönfelder, G. (2010) · Environmental Health Perspectives · doi:10.1289/ehp.0901717 · Cited by 166 · see citing works
Hanna, C. W., Bloom, M. S., Robinson, W. P., Kim, D., Parsons, P. J., vom Saal, F. S., Taylor, J. A., Steuerwald, A. J., & Fujimoto, V. Y. (2012) · Human Reproduction · doi:10.1093/humrep/des038 · Cited by 163 · see citing works
Epigenetic effects of endocrine-disrupting chemicals on female reproduction: An ovarian perspective
Zama, A. M., & Uzumcu, M. (2010) · Frontiers in Neuroendocrinology · doi:10.1016/j.yfrne.2010.06.003 · Cited by 165 · see citing works
EFSA Panel on food contact materials, E. (2010) · EFSA Journal · doi:10.2903/j.efsa.2010.1829 · Cited by 165 · see citing works
Neurological Effects of Bisphenol A and its Analogues
Inadera, H. (2015) · International Journal of Medical Sciences · doi:10.7150/ijms.13267 · Cited by 159 · see citing works
Shafei, A., Ramzy, M. M., Hegazy, A. I., Husseny, A. K., EL-hadary, U. G., Taha, M. M., & Mosa, A. A. (2018) · Gene · doi:10.1016/j.gene.2018.01.016 · Cited by 158 · see citing works
Adverse Effects of Bisphenol A on Male Reproductive Function
Manfo, F. P. T., Jubendradass, R., Nantia, E. A., Moundipa, P. F., & Mathur, P. P. (2013) · Reviews of Environmental Contamination and Toxicology · doi:10.1007/978-3-319-01619-1_3 · Cited by 154 · see citing works
Prins, G. S., Ye, S.-H., Birch, L. A., Ho, S., & Kannan, K. (2010) · Reproductive Toxicology · doi:10.1016/j.reprotox.2010.09.009 · Cited by 152 · see citing works
Mikołajewska, K., Stragierowicz, J., & Gromadzińska, J. (2015) · International Journal of Occupational Medicine and Environmental Health · doi:10.13075/ijomeh.1896.00343 · Cited by 153 · see citing works
Recent trends in biomonitoring of bisphenol A, 4-t-octylphenol, and 4-nonylphenol
Asimakopoulos, A. G., Τhomaidis, Ν. S., & Koupparis, M. Α. (2011) · Toxicology Letters · doi:10.1016/j.toxlet.2011.07.032 · Cited by 151 · see citing works
Veiga‐Lopez, A., Luense, L. J., Christenson, L. K., & Padmanabhan, V. (2013) · Endocrinology · doi:10.1210/en.2012-2129 · Cited by 148 · see citing works
Effects of Low Doses of Bisphenol A on the Metabolome of Perinatally Exposed CD-1 Mice
Cabaton, N. J., Canlet, C., Wadia, P. R., Tremblay‐Franco, M., Gautier, R., Molina, J., Sonnenschein, C., Cravedi, J., Rubin, B. S., Soto, A. M., et al. (2013) · Environmental Health Perspectives · doi:10.1289/ehp.1205588 · Cited by 147 · see citing works
Predictors of urinary bisphenol A and phthalate metabolite concentrations in Mexican children
Lewis, R. C., Meeker, J. D., Peterson, K. E., Lee, J. M., Pace, G. G., Cantoral, A., & Téllez‐Rojo, M. M. (2013) · Chemosphere · doi:10.1016/j.chemosphere.2013.08.038 · Cited by 145 · see citing works
Bisphenol A and children's health
Braun, J. M., & Hauser, R. B. (2011) · Current Opinion in Pediatrics · doi:10.1097/mop.0b013e3283445675 · Cited by 143 · see citing works
Self-citationDo, T., Baral, E. R., & Kim, J. G. (2018) · Polymer · doi:10.1016/j.polymer.2018.04.015 · Cited by 143 · see citing works
Casas, M., Valvi, D., Luque, N., Ballesteros‐Gómez, A., Carsin, A., Fernandez, M. F., Koch, H. M., Méndez, M. A., Sunyer, J., Rubio, S., et al. (2013) · Environment International · doi:10.1016/j.envint.2013.02.014 · Cited by 139 · see citing works
Gruber, E. S., Stadlbauer, V., Pichler, V., Resch‐Fauster, K., Todorovic, A., Meisel, T., Trawoeger, S., Hollóczki, O., Turner, S., Wadsak, W., et al. (2022) · Exposure and Health · doi:10.1007/s12403-022-00470-8 · Cited by 112 · see citing works
Impact of hospital-based environmental exposures on neurodevelopmental outcomes of preterm infants
Santos, J., Pearce, S. E., & Stroustrup, A. (2015) · Current Opinion in Pediatrics · doi:10.1097/mop.0000000000000190 · Cited by 135 · see citing works
Estrogenic Effects of Several BPA Analogs in the Developing Zebrafish Brain
Cano‐Nicolau, J., Vaillant, C., Pellegrini, E., Charlier, T. D., Kah, O., & Coumailleau, P. (2016) · Frontiers in Neuroscience · doi:10.3389/fnins.2016.00112 · Cited by 135 · see citing works
Bisphenol A-induced metabolic disorders: From exposure to mechanism of action
Akash, M. S. H., Sabir, S., & Rehman, K. (2020) · Environmental Toxicology and Pharmacology · doi:10.1016/j.etap.2020.103373 · Cited by 133 · see citing works
Recent advances on bisphenol-A and endocrine disruptor effects on human prostate cancer
Donato, M. D., Cernera, G., Giovannelli, P., Galasso, G., Bilancio, A., Migliaccio, A., & Castoria, G. (2017) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2017.02.045 · Cited by 130 · see citing works
Concentration of bisphenol A in thermal paper
Mendum, T., Stoler, E., VanBenschoten, H., & Warner, J. C. (2010) · Green Chemistry Letters and Reviews · doi:10.1080/17518253.2010.502908 · Cited by 128 · see citing works
Meng, Z., Tian, S., Yan, J., Jia, M., Yan, S., Li, R., Zhang, R., Zhu, W., & Zhou, Z. (2019) · Environmental Pollution · doi:10.1016/j.envpol.2019.01.116 · Cited by 128 · see citing works
Kim, S., Kim, S., Won, S., & Choi, K. (2017) · Environment International · doi:10.1016/j.envint.2017.06.013 · Cited by 127 · see citing works
Chemical Properties, Environmental Fate, and Degradation of Seven Classes of Pollutants
Manzetti, S., van der Spoel, E. R., & van der Spoel, D. (2014) · Chemical Research in Toxicology · doi:10.1021/tx500014w · Cited by 125 · see citing works
Hu, W.-Y., Shi, G., Hu, D.-P., Nelles, J. L., & Prins, G. S. (2011) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2011.08.032 · Cited by 118 · see citing works
The Adverse Cardiac Effects of Di(2-ethylhexyl)phthalate and Bisphenol A
Posnack, N. G. (2014) · Cardiovascular Toxicology · doi:10.1007/s12012-014-9258-y · Cited by 116 · see citing works
Préau, L., Fini, J., Morvan-Dubois, G., & DEMENEIX, B. A. (2014) · Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms · doi:10.1016/j.bbagrm.2014.06.015 · Cited by 116 · see citing works
Urinary Paraben Concentrations and Ovarian Aging among Women from a Fertility Center
Smith, K. W., Souter, I. C., Dimitriadis, I., Ehrlich, S., Williams, P. L., Calafat, A. M., & Hauser, R. B. (2013) · Environmental Health Perspectives · doi:10.1289/ehp.1205350 · Cited by 118 · see citing works
Self-citationPharmacokinetics of bisphenol A in neonatal and adult rhesus monkeys
Doerge, D. R., Twaddle, N. C., Woodling, K. A., & Fisher, J. W. (2010) · Toxicology and Applied Pharmacology · doi:10.1016/j.taap.2010.07.009 · Cited by 109 · see citing works
Obesogenic Endocrine Disrupting Chemicals: Identifying Knowledge Gaps
Veiga‐Lopez, A., Pu, Y., Gingrich, J., & Padmanabhan, V. (2018) · Trends in Endocrinology and Metabolism · doi:10.1016/j.tem.2018.06.003 · Cited by 111 · see citing works
Bisphenol A, an endocrine‐disrupting chemical, and brain development
Itoh, K., Yaoi, T., & Fushiki, S. (2012) · Neuropathology · doi:10.1111/j.1440-1789.2011.01287.x · Cited by 102 · see citing works
Teeguarden, J., & Hanson-Drury, S. (2013) · Food and Chemical Toxicology · doi:10.1016/j.fct.2013.07.007 · Cited by 98 · see citing works
Determination of free and total bisphenol A in urine of infants
Völkel, W., Kiranoglu, M., & Fromme, H. (2010) · Environmental Research · doi:10.1016/j.envres.2010.10.001 · Cited by 97 · see citing works
Ramadan, M., Cooper, B. L., & Posnack, N. G. (2020) · Birth Defects Research · doi:10.1002/bdr2.1752 · Cited by 98 · see citing works
Zhang, Y., Wei, F., Zhang, J., Hao, L., Jiang, J., Dang, L., Mei, D., Fan, S., Yu, Y., & Jiang, L. (2017) · Archives of Biochemistry and Biophysics · doi:10.1016/j.abb.2017.09.002 · Cited by 97 · see citing works
Wang, H., Li, Q., Zhang, S., Chen, Z., Wang, W., Zhao, G., Zhuang, L., Hu, B., & Wang, X. (2018) · Catalysis Today · doi:10.1016/j.cattod.2018.09.037 · Cited by 95 · see citing works
Fisher, J. W., Twaddle, N. C., Vanlandingham, M. M., & Doerge, D. R. (2011) · Toxicology and Applied Pharmacology · doi:10.1016/j.taap.2011.08.026 · Cited by 93 · see citing works
Teeguarden, J., Hanson-Drury, S., Fisher, J. W., & Doerge, D. R. (2013) · Food and Chemical Toxicology · doi:10.1016/j.fct.2013.08.001 · Cited by 93 · see citing works
Huygh, J., Clotman, K., Malarvannan, G., Covaci, A., Schepens, T., Verbrugghe, W., Dirinck, E. L., Gaal, L. V., & Jorens, P. G. (2015) · Environment International · doi:10.1016/j.envint.2015.04.008 · Cited by 88 · see citing works
Potential Sources of Bisphenol A in the Neonatal Intensive Care Unit
Duty, S. M., Mendonca, K., Hauser, R. B., Calafat, A. M., Ye, X., Meeker, J. D., Ackerman, R. M., Cullinane, J., Atinaja-Faller, J., & Ringer, S. A. (2013) · PEDIATRICS · doi:10.1542/peds.2012-1380 · Cited by 87 · see citing works
Self-citationMaternal and infant exposure to environmental phenols as measured in multiple biological matrices
Arbuckle, T. E., Weiss, L., Fisher, M. M., Hauser, R. B., Dumas, P., Bérubé, R., Neisa, A., LeBlanc, A., Lang, C., Ayotte, P., et al. (2014) · The Science of The Total Environment · doi:10.1016/j.scitotenv.2014.10.107 · Cited by 86 · see citing works
Self-citationTyl, R. W. (2009) · Environmental Health Perspectives · doi:10.1289/ehp.0900893 · Cited by 86 · see citing works
Adewale, H. B., Todd, K. L., Mickens, J. A., & Patisaul, H. B. (2011) · NeuroToxicology · doi:10.1016/j.neuro.2010.07.008 · Cited by 86 · see citing works
Key Characteristics of Cardiovascular Toxicants
Lind, L., Araujo, J. A., Barchowsky, A., Belcher, S. M., Berridge, B. R., Chiamvimonvat, N., Chiu, W. A., Cogliano, V. J., Elmore, S., Farraj, A. K., et al. (2021) · Environmental Health Perspectives · doi:10.1289/ehp9321 · Cited by 86 · see citing works
Analytical methods for the determination of personal care products in human samples: An overview
Jiménez-Díaz, I., Zafra‐Gómez, A., Ballesteros, O., & Navalón, A. (2014) · Talanta · doi:10.1016/j.talanta.2014.05.052 · Cited by 81 · see citing works
Polinski, K. J., Dabelea, D., Hamman, R. F., Adgate, J. L., Calafat, A. M., Ye, X., & Starling, A. P. (2018) · Environmental Research · doi:10.1016/j.envres.2018.01.025 · Cited by 83 · see citing works
Self-citationLiu, Y., & Lu, X. (2022) · Journal of Polymer Science · doi:10.1002/pol.20220118 · Cited by 81 · see citing works
Morgan, M. K., Jones, P. A., Calafat, A. M., Ye, X., Croghan, C. W., Chuang, J. C., Wilson, N. K., Clifton, M. S., Figueroa, Z. I., & Sheldon, L. S. (2011) · Environmental Science & Technology · doi:10.1021/es200537u · Cited by 78 · see citing works
Self-citationIjaz, S., Ullah, A., Shaheen, G., & Jahan, S. (2019) · Toxicology Mechanisms and Methods · doi:10.1080/15376516.2019.1652873 · Cited by 78 · see citing works
Calafat, A. M., & Needham, L. L. (2009) · Environmental Health Perspectives · doi:10.1289/ehp.0901108 · Cited by 78 · see citing works
Self-citation
- Authors
- Calafat, A. M., Weuve, J., Ye, X., Jia, L. T., Hu, H., Ringer, S., Huttner, K., & Hauser, R.
- Affiliations
- Centers for Disease Control and Prevention (US)
- Rush University Medical Center (US)
- University of Michigan (US)
- Brigham and Women's Hospital (US)
- Neonatology Unit and
- Harvard University (US)
- Corresponding author
- Calafat, Antonia M.
- Venue
- Environmental Health Perspectives
- Publisher
- American Chemical Society (ACS)
- Published
- 2008-12-10
- Volume
- 117
- Issue
- 4
- Pages
- 639-644
- ISSN
- 0091-6765 (ISSN-L)
- 1552-9924
- PMC
- PMC2679610
- OpenAlex
- W2119352549
- Cited by
- 374
- References
- 47
- Citations by year
- 2026: 9 · 2025: 13 · 2024: 20 · 2023: 10 · 2022: 28 · 2021: 21 · 2020: 23 · 2019: 18 · 2018: 26 · 2017: 25 · 2016: 17 · 2015: 36 · 2014: 19 · 2013: 31 · 2012: 28
- FWCI
- 11.52
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- public-domain
- creativecommons.org/licenses/by/4.0/ (vor, 3306 d)
- Locations
- Environmental Health Perspectives (publishedVersion, public-domain)
- PubMed Central (publishedVersion, public-domain)
- PubMed (publishedVersion)
- Digital Access to Scholarship at Harvard (DASH) (Harvard University) (submittedVersion, cc-by)
- Topics
- Physical Sciences › Environmental Science › Health, Toxicology and Mutagenesis › Effects and risks of endocrine disrupting chemicals
- Physical Sciences › Environmental Science › Health, Toxicology and Mutagenesis › Toxic Organic Pollutants Impact
- Physical Sciences › Environmental Science › Health, Toxicology and Mutagenesis › Health, Environment, Cognitive Aging
- Keywords
- bisphenol A, phenols, preterm infants, neonatal intensive care, DEHP, DEHP metabolites, urinary biomonitoring, triclosan, benzophenone-3, methylparaben, propylparaben, endocrine disruptors
- MeSH terms
- Bisphenol A Compounds, Benzhydryl Compounds, Benzophenones, Diethylhexyl Phthalate, Environmental Exposure, Equipment and Supplies, Estrogens, Non-Steroidal, Female, Humans, Infant, Newborn, Infant, Premature, Intensive Care Units, Neonatal, Male, Parabens, Phenols, Plasticizers, Risk Factors, Triclosan, Epidemiologic Studies
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review