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PrEP Stigma: Implicit and Explicit Drivers of Disparity
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Purpose of review Despite its promise as an HIV prevention strategy, PrEP uptake remains slow, especially among highest priority populations. One factor that may be impeding implementation and driving disparities is PrEP-related stigma. This paper reviews the role of PrEP-related stigma in PrEP access, adherence, and persistence and examines its antecedents and consequences. Recent findings Although PrEP stigma is often experienced at the community level (i.e., by potential and current users), it can be reinforced and even amplified by public health programs, policy, and research. PrEP stigma disproportionately impacts disadvantaged groups and impedes scalability by influencing behavior of both patients and providers. Reducing PrEP stigma and its negative impact on the epidemic requires a significant shift in perspective, language, and programs. Such a shift is necessary to ensure broader reach of PrEP as a prevention strategy and improve its utilization by the individuals who need it most.
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“In terms of health domains, HIV/AIDS accounted for 40% of included studies, consistent with prior reviews (112).”
From Applications and implementation considerations for stepped-wedge designs in sub-Saharan Africa: a systematic review (2026) · cites this paper as [112]
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Metadata
- Authors
- Golub, S. A.
- Affiliations
- The Graduate Center, CUNY (US)
- Corresponding author
- Golub, Sarit A.
- ORCID
- Golub, Sarit A.
- Venue
- Current HIV/AIDS Reports
- Published
- 2018-02-19
- Volume
- 15
- Issue
- 2
- Pages
- 190-197
- ISSN
- 1548-3568 (ISSN-L)
- 1548-3576
- PMC
- PMC5884731
- OpenAlex
- W2792635178
- Cited by
- 383
- References
- 67
- Citations by year
- 2026: 47 · 2025: 56 · 2024: 52 · 2023: 50 · 2022: 51 · 2021: 63 · 2020: 39 · 2019: 21 · 2018: 4
- FWCI
- 4.65
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Licence
- www.springer.com/tdm (tdm)
- Locations
- Current HIV/AIDS Reports (publishedVersion)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- Funders
- Gilead Sciences
- Topics
- Health Sciences › Medicine › Infectious Diseases › HIV/AIDS Research and Interventions
- Health Sciences › Medicine › Epidemiology › HIV, Drug Use, Sexual Risk
- Health Sciences › Medicine › Infectious Diseases › HIV/AIDS drug development and treatment
- Keywords
- HIV PrEP, PrEP stigma, HIV prevention, PrEP uptake, health disparities, PrEP adherence, PrEP persistence, HIV prevention programs, HIV prevention policy, HIV prevention research, provider behavior, community stigma
- MeSH terms
- Humans, Male, HIV Infections, Anti-HIV Agents, Social Stigma, Pre-Exposure Prophylaxis
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