The DOI matches its Crossref record; 36 of the 36 references it cites were found in a registry or an index.
Variability in recovery from aphasia
Abstract
Clinicians have long recognized the enormous variability of recovery among patients with aphasia. Accordingly, the identification of specific factors most important in determining the extent of recovery has been the subject of many investigations. Yet, the reasons for two patients of the same age, nearly identical clinical presentations, and similar MRI findings having completely dissimilar recoveries are still unknown. It remains difficult for a clinician to make a valid prognosis of language recovery in an individual patient. This article provides a review of aphasia-recovery research and a framework for approaching the variability of recovery in clinical practice.
Overview
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“It is well established that inter-individual variability in TLI in post-stroke aphasia is influenced by an array of factors, including, but not limited to, age12–15, education16–19, aphasia severity11,14,15,20,21, baseline cognitive abilities13,22,23, and, specific to bPWA, bilingual language experience and language of treatment (e.g., whether therapy is delivered in L1 or L2)24,25.”
From Machine Learning Predictions of Recovery in Bilingual Poststroke Aphasia: Aligning Insights With Clinical Evidence (2025) · cites this paper as [16]
Citations
Cites
Sex differences in the functional organization of the brain for language
Shaywitz, B. A., Shaywltz, S. E., Pugh, K. R., Constable, R. T., Skudlarski, P., Fulbright, R. K., Bronen, R. A., Fletcher, J. M., Shankweiler, D., Katz, L., et al. (1995) · Nature · doi:10.1038/373607a0 · Cited by 1,374
Speech and language therapy for aphasia following stroke
Brady, M. C., Kelly, H., Godwin, J., Enderby, P., & Campbell, P. (2016) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd000425.pub4 · Cited by 1,159
Aphasia in acute stroke: Incidence, determinants, and recovery
Pedersen, P. M., Jørgensen, H. S., Nakayama, H., Raaschou, H. O., & Olsen, T. S. (1995) · Annals of Neurology · doi:10.1002/ana.410380416 · Cited by 823
Aphasia after Stroke: Type, Severity and Prognosis
Pedersen, P. M., Vinter, K., & Olsen, T. S. (2003) · Cerebrovascular Diseases · doi:10.1159/000073896 · Cited by 627
Evaluating Single-Subject Treatment Research: Lessons Learned from the Aphasia Literature
Beeson, P. M., & Robey, R. R. (2006) · Neuropsychology Review · doi:10.1007/s11065-006-9013-7 · Cited by 549 · cited 1×
“the everyday functional requirements of the individual [ 35 ,36], even years after injury.”
BackgroundAphasia in acute stroke and relation to outcome
Laska, A. C., Hellblom, A., Murray, V., Kahan, T., & von Arbin, M. (2001) · Journal of Internal Medicine · doi:10.1046/j.1365-2796.2001.00812.x · Cited by 528
RECOVERY PATTERNS AND PROGNOSIS IN APHASIA
KERTESZ, A. E., & MCCABE, P. (1977) · Brain · doi:10.1093/brain/100.1.1 · Cited by 515
Aphasia after stroke: natural history and associated deficits.
Wade, D. T., Hewer, R. L., DAVID, R. M., & Enderby, P. (1986) · Journal of Neurology Neurosurgery & Psychiatry · doi:10.1136/jnnp.49.1.11 · Cited by 417
Hillis, A. E. (2007) · Neurology · doi:10.1212/01.wnl.0000265600.69385.6f · Cited by 318
NAESER, M. A., PALUMBO, C. L., HELM-ESTABROOKS, N., STIASSNY-EDER, D., & ALBERT, M. L. (1989) · Brain · doi:10.1093/brain/112.1.1 · Cited by 298
Left brain, right brain : perspectives from cognitive neuroscience
Springer, S. P., & DEUTSCH, G. (1998) · Medical Entomology and Zoology · Cited by 294
Computer tomographic localization, lesion size, and prognosis in aphasia and nonverbal impairment
KERTESZ, A. E., Harlock, W., & Coates, R. (1979) · Brain and Language · doi:10.1016/0093-934x(79)90038-5 · Cited by 248
Comparison of Clinic, Home, and Deferred Language Treatment for Aphasia
Wertz, R. T. (1986) · Archives of Neurology · doi:10.1001/archneur.1986.00520070011008 · Cited by 246
Variability in language recovery after first-time stroke
Lazar, R. M., Speizer, A., Festa, J. R., Krakauer, J. W., & Marshall, R. S. (2007) · Journal of Neurology Neurosurgery & Psychiatry · doi:10.1136/jnnp.2007.122457 · Cited by 217
Self-citationEvolution of Aphasia and Language Rehabilitation: A Retrospective Exploratory Study
Vignolo, L. A. (1964) · Cortex · doi:10.1016/s0010-9452(64)80008-3 · Cited by 184
Spontaneous recovery of language in patients with aphasia between 4 and 34 weeks after stroke.
Lendrem, W., & Lincoln, N. B. (1985) · Journal of Neurology Neurosurgery & Psychiatry · doi:10.1136/jnnp.48.8.743 · Cited by 170
Naeser, M. A., Helm‐Estabrooks, N., Haas, G. L., Auerbach, S. H., & Srinivasan, M. (1987) · Archives of Neurology · doi:10.1001/archneur.1987.00520130057018 · Cited by 158
The natural history of acute cerebrovascular disease: a retrospective study of 769 patients.
Marquardsen, J. (1969) · PubMed · Cited by 133
Aphasia during the Acute Phase in Ischemic Stroke
Inatomi, Y., Yonehara, T., Omiya, S., Hashimoto, Y., Hirano, T., & Uchino, M. (2008) · Cerebrovascular Diseases · doi:10.1159/000118376 · Cited by 131
Selnes, O. A., Knopman, D. S., Niccum, N., Rubens, A. B., & Larson, D. A. (1983) · Annals of Neurology · doi:10.1002/ana.410130515 · Cited by 128
The Structural Determinants of Recovery in Wernicke′s Aphasia
KERTESZ, A. E., Lau, W. K., & Polk, M. J. (1993) · Brain and Language · doi:10.1006/brln.1993.1010 · Cited by 126
THE EPIDEMIOLOGY OF APHASIC AND COGNITIVE IMPAIRMENT IN STROKE
KERTESZ, A. E., & Sheppard, A. (1981) · Brain · doi:10.1093/brain/104.1.117 · Cited by 120
Godefroy, O., Dubois, C., Debachy, B., Leclerc, M., & Kreisler, A. (2002) · Stroke · doi:10.1161/hs0302.103653 · Cited by 119
Recovery in treated aphasia in the first year post-stroke.
Sarno, M. T., & Levita, E. (1979) · Stroke · doi:10.1161/01.str.10.6.663 · Cited by 113
Quantitative study of the rate of recovery from aphasia due to ischemic stroke.
Demeurisse, G., Demol, O., Derouck, M., De Beuckelaer, R., Coekaerts, M. J., & Capon, A. (1980) · Stroke · doi:10.1161/01.str.11.5.455 · Cited by 106
Bakheit, A. M. O., Shaw, S. R., Carrington, S., & Griffiths, S. (2007) · Clinical Rehabilitation · doi:10.1177/0269215507078452 · Cited by 101
Speech and language therapy for aphasia following stroke
Greener, J., Enderby, P., & Whurr, R. (1999) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd000425 · Cited by 98
Code, C. (2001) · Brain and Language · doi:10.1006/brln.2000.2420 · Cited by 82
Evolution of Aphasia in the First Year Post-Onset
Pashek, G. V., & Holland, A. L. (1988) · Cortex · doi:10.1016/s0010-9452(88)80004-2 · Cited by 77
Recovery from aphasia following brain injury: the role of reorganization
Marsh, E. B., & Hillis, A. E. (2006) · Progress in brain research · doi:10.1016/s0079-6123(06)57009-8 · Cited by 67
Effect of Socioeconomic Status on Aphasia Severity and Recovery
Connor, L. T., Obler, L. K., Tocco, M., Fitzpatrick, P. M., & Albert, M. L. (2001) · Brain and Language · doi:10.1006/brln.2001.2459 · Cited by 62
Predictors of Language Restitution Following Stroke
Holland, A. L., Greenhouse, J. B., Fromm, D., & Swindell, C. S. (1989) · Journal of Speech Language and Hearing Research · doi:10.1044/jshr.3202.232 · Cited by 55
Naeser, M. A., Palumbo, C. L., Prete, M. N., Fitzpatrick, P. M., Mimura, M., Samaraweera, R. N., & Albert, M. L. (1998) · Brain and Language · doi:10.1006/brln.1997.1866 · Cited by 53
Aphasia after stroke: a detailed study of recovery in the first 3 months
Enderby, P., WOOD, V. A., Wade, D. T., & Hewer, R. L. (1986) · International Rehabilitation Medicine · doi:10.3109/03790798709166207 · Cited by 36
Basso, A., FAGLIONI, P., & La, V. (1975) · PubMed · Cited by 30
THE RED NUCLEUS, THE CEREBELLUM AND THE INFERIOR OLIVE IN MAN
Verhaart, W. J. C. (2009) · Acta Neurologica Scandinavica · doi:10.1111/j.1600-0404.1962.tb01079.x · Cited by 15
Research works printed but not linked: 1
- Saffran EM, Bogyo LC, Schwartz M, et al.: Does deep dyslexia reflect right hemisphere reading? In Deep Dyslexia. Edited by Coltheart M, Patterson K, Marshall J. London: Routledge and Kegan Paul; 1980:381–406.
Cited by
Sorted by citations
Stroke, Cognitive Deficits, and Rehabilitation: Still an Incomplete Picture
Cumming, T. B., Marshall, R. S., & Lazar, R. M. (2012) · International Journal of Stroke · doi:10.1111/j.1747-4949.2012.00972.x · Cited by 435
Self-citationImprovement in Aphasia Scores After Stroke Is Well Predicted by Initial Severity
Lazar, R. M., Minzer, B., Antoniello, D., Festa, J. R., Krakauer, J. W., & Marshall, R. S. (2010) · Stroke · doi:10.1161/strokeaha.109.577338 · Cited by 291
Self-citationPredicting outcome and recovery after stroke with lesions extracted from MRI images
Hope, T. M. H., Seghier, M. L., Leff, A. P., & Price, C. J. (2013) · NeuroImage: Clinical · doi:10.1016/j.nicl.2013.03.005 · Cited by 243
Re-emergence of modular brain networks in stroke recovery
Siegel, J. S., Seitzman, B. A., Ramsey, L., Ortega, M., Gordon, E. M., Dosenbach, N. U. F., Petersen, S. E., Shulman, G. L., & Corbetta, M. (2018) · Cortex · doi:10.1016/j.cortex.2017.12.019 · Cited by 237
Impairment of speech production predicted by lesion load of the left arcuate fasciculus
Marchina, S., Zhu, L. L., Norton, A., Zipse, L., Wan, C. Y., & Schlaug, G. (2011) · Stroke · doi:10.1161/strokeaha.110.606103 · Cited by 230
Metadata
- Authors
- Lazar, R. M., & Antoniello, D.
- Affiliations
- Columbia University Irving Medical Center (US)
- Corresponding author
- Lazar, Ronald M.
- Venue
- Current Neurology and Neuroscience Reports
- Published
- 2008-11
- Volume
- 8
- Issue
- 6
- Pages
- 497-502
- ISSN
- 1528-4042 (ISSN-L)
- 1534-6293
- OpenAlex
- W2083676933
- Cited by
- 132
- References
- 36
- Citations by year
- 2026: 3 · 2025: 5 · 2024: 7 · 2023: 18 · 2022: 12 · 2021: 10 · 2020: 10 · 2019: 7 · 2018: 7 · 2017: 6 · 2016: 9 · 2015: 8 · 2014: 3 · 2013: 8 · 2012: 2
- FWCI
- 0.43
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- www.springer.com/tdm (tdm)
- Locations
- Current Neurology and Neuroscience Reports (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (R01HD043249)
- Topics
- Life Sciences › Neuroscience › Cognitive Neuroscience › Neurobiology of Language and Bilingualism
- Health Sciences › Medicine › Clinical Neurology › Traumatic Brain Injury Research
- Health Sciences › Medicine › Rehabilitation › Stroke Rehabilitation and Recovery
- Keywords
- aphasia, language recovery, prognosis, predictors of recovery, stroke, brain MRI findings
- MeSH terms
- Stroke Rehabilitation, Aphasia, Female, Humans, Functional Laterality, Male, Neuropsychological Tests, Recovery of Function, Stroke
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review