Substance use disorder and personality disorder
Abstract
Personality disorders (PDs) and substance use disorders (SUDs) frequently co-occur in both the general population and in clinical settings. Literature is reviewed documenting high comorbidity between these two classes of disorders, possible mechanisms of comorbidity, and the clinical implications of this comorbidity. Special emphasis is given to antisocial personality disorder (ASPD) and borderline personality disorder (BPD) as these disorders not only co-occur frequently with SUDs in the clinical populations and present clinical challenges, but also because recent research points to etiologic processes that are common to these specific PDs and SUDs. Although most attention on comorbidity between PDs and SUDs has focused on ASPD and BPD, it is also clear that other PDs (in particular, avoidant PD and paranoid PD) are prevalent among those suffering from SUDs.
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Another influential dispositional profile combines high negative emotionality, impulsivity, and low agreeableness.
“Another influential dispositional profile combines high negative emotionality, impulsivity, and low agreeableness (Sher and Trull 2002; Krueger et al. 2002; Miller et al. 2003).”
From Decoding the bidirectional links between alcohol misuse and aggression: toward a unified translational framework (2026) · cites this paper as Sher and Trull 2002
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Affective Factors in the Co-Occurrence of Personality Disorders and Substance Use Disorders
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Borderline Personality Disorder: Contemporary Approaches to Conceptualization and Etiology
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Self-citationProfile of egyptian patients with borderline personality disorder with and without comorbidity
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Birds of a Feather Flock Together: Concurrent Personality Disorders and Substance Use Disorders
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Alcohol Use and Alcohol Use Disorders
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Self-citationSubstance use disorders and unauthorized drug use in an Australian forensic mental health hospital
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- Authors
- Sher, K. J., & Trull, T. J.
- Affiliations
- University of Missouri (US)
- Venue
- Current Psychiatry Reports
- Published
- 2002-01
- Volume
- 4
- Issue
- 1
- Pages
- 25-29
- ISSN
- 1523-3812 (ISSN-L)
- 1535-1645
- OpenAlex
- W1965263208
- Cited by
- 84
- References
- 53
- Citations by year
- 2026: 2 · 2025: 4 · 2024: 3 · 2023: 7 · 2022: 7 · 2021: 8 · 2020: 2 · 2019: 5 · 2018: 7 · 2017: 1 · 2016: 6 · 2015: 2 · 2014: 5 · 2013: 4 · 2012: 5
- FWCI
- 0.18
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- www.springer.com/tdm (tdm)
- Locations
- Current Psychiatry Reports (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Institute on Alcohol Abuse and Alcoholism (R01 AA07231, R01AA007231, P50AA011998)
- National Institute of Mental Health (R01MH52695, R01MH052695)
- Topics
- Social Sciences › Psychology › Clinical Psychology › Personality Disorders and Psychopathology
- Health Sciences › Medicine › Epidemiology › Substance Abuse Treatment and Outcomes
- Social Sciences › Psychology › Clinical Psychology › Personality Traits and Psychology
- Keywords
- substance use disorders, personality disorders, comorbidities, antisocial personality disorder, borderline personality disorder, avoidant personality disorder, paranoid personality disorder
- MeSH terms
- Humans, Personality Disorders, Comorbidity, Substance-Related Disorders
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