Pro-Resolving Lipid Mediators Improve Neuronal Survival and Increase Aβ42 Phagocytosis

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Immunoresolvent Resolvin D1 Maintains the Health of the Ocular Surface

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Maresin1 Decreased Microglial Chemotaxis and Ameliorated Inflammation Induced by Amyloid-β 42 in Neuron-Microglia Co-Culture Models

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DHA Selectively Protects SAMP-8-Associated Cognitive Deficits Through Inhibition of JNK

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Resolvin D1 Attenuates Innate Immune Reactions in Experimental Subarachnoid Hemorrhage Rat Model

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Pro-resolving lipid mediators in diseases: exploring the molecular basis and clinical implication

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Sex and Age-Related Differences in Neuroinflammation and Apoptosis in Balb/c Mice Retina Involve Resolvin D1

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Prostaglandins in the Inflamed Central Nervous System: Potential Therapeutic Targets

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Pathogenesis, Animal Models, and Drug Discovery of Alzheimer’s Disease

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Bioenergetics and lipid metabolism in Alzheimer's disease: From cell biology to systemic health

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Microglia Biomarkers in Alzheimer’s Disease

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Aging, sex, metabolic and life experience factors: Contributions to neuro-inflammaging in Alzheimer’s disease research

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Sleep Disturbance and Alzheimer’s Disease: The Glial Connection

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Differential effect of an evolving amyloid and tau pathology on brain phospholipids and bioactive lipid mediators in rat models of Alzheimer-like pathology

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The role of n-3-derived specialised pro-resolving mediators (SPMs) in microglial mitochondrial respiration and inflammation resolution in Alzheimer’s disease

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Probing changes in brain esterified oxylipin concentrations during the early stages of pathogenesis in Alzheimer’s Disease transgenic rats

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Docosahexaenoic acid inhibits ischemic stroke to reduce vascular dementia and Alzheimer’s disease

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Neuroprotective effects of some epigenetic modifying drugs’ on Chlamydia pneumoniae-induced neuroinflammation: A novel model

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Reduced Levels of Plasma Lipoxin A4 Are Associated with Post-Stroke Cognitive Impairment

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Prostaglandin E2, 9S-, 13S-HODE and resolvin D1 are strongly associated with the post-stroke cognitive impairment

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Pharmacokinetics and Changes in Lipid Mediator Profiling after Consumption of Specialized Pro-Resolving Lipid-Mediator-Enriched Marine Oil in Healthy Subjects

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n-3 Polyunsaturated Fatty Acids Modulate LPS-Induced ARDS and the Lung–Brain Axis of Communication in Wild-Type versus Fat-1 Mice Genetically Modified for Leukotriene B4 Receptor 1 or Chemerin Receptor 23 Knockout

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NPD1 Enhances Autophagy and Reduces Hyperphosphorylated Tau and Amyloid-β42 by Inhibiting GSK3β Activation in N2a/APP695swe Cells

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Lipoxins A4 and B4 inhibit glial cell activation via CXCR3 signaling in acute retinal neuroinflammation

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High throughput screening of mesenchymal stromal cell morphological response to inflammatory signals for bioreactor-based manufacturing of extracellular vesicles that modulate microglia

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Eicosanoid signaling in neuroinflammation associated with Alzheimer's disease

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The Multifaceted Role of Neuroprotectin D1: Physiological, Pathophysiological, and Pharmacological Insights in Neurodegenerative Diseases

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Prospective study on Maresin-1 and cytokine levels in medication-naïve adolescents with first-episode major depressive disorder

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Maresin1: A multifunctional regulator in inflammatory bone diseases

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Ultra‐Performance Liquid Chromatography‐Mass Spectrometry Analysis of Free and Esterified Oxygenated Derivatives from Docosahexaenoic Acid in Rat Brain

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Intravenous chaperone treatment of late-stage Alzheimer´s disease (AD) mouse model affects amyloid plaque load, reactive gliosis and AD-related genes

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The Evolving Role of Specialized Pro-resolving Mediators in Modulating Neuroinflammation in Perioperative Neurocognitive Disorders

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Mass Spectrometry-Based Analysis of Lipid Involvement in Alzheimer’s Disease Pathology—A Review

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Exploiting formyl peptide receptor 2 to promote microglial resolution: a new approach to Alzheimer’s disease treatment

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Research progress in the mechanisms and functions of specialized pro-resolving mediators in neurological diseases

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Fundamentals of and Critical Issues in Lipid Autacoid Medicine: A Review

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Molecular underpinnings of programming by early-life stress and the protective effects of early dietary ω6/ω3 ratio, basally and in response to LPS: Integrated mRNA-miRNAs approach

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Pro-resolving lipid mediator reduces amyloid-β42–induced gene expression in human monocyte–derived microglia

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Oligomeropathies, inflammation and prion protein binding

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Neurons regulate the esterification of bioactive lipid mediators in the brain of acid sphingomyelinase deficient mice

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A single meal has the potential to alter brain oxylipin content

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Maresins

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Early evidence of beneficial and protective effects of Protectin DX treatment on behavior responses and type-1 diabetes mellitus related-parameters: A non-clinical approach

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Current experimental methods to investigate the impact of specialized pro-resolving lipid mediators on Sjögren’s syndrome

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Maresin-like 1 Ameliorates Neuropathology of Alzheimer’s Disease in Brains of a Transgenic Mouse Model

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Can Dietary n-3 Polyunsaturated Fatty Acids Affect Apelin and Resolvin in Testis and Sperm of Male Rabbits?

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Sphingosine kinase-dependent regulation of pro-resolving lipid mediators in Alzheimer's disease

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Neuroinflammation in Preclinical Alzheimer's Disease: A Review of Current Evidence

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Integrating downstream mediators of Omega-3 fatty acids into enteral nutrition for improved patient care: An expert panel consensus

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Unveiling enigmatic essence of Sphingolipids: A promising avenue for glaucoma treatment

Iezhitsa, I. N., Agarwal, R., & Agarwal, P. (2024) · Vision Research · doi:10.1016/j.visres.2024.108434 · Cited by 4

Maresin1 restrains chronic inflammation and Aβ production to ameliorate Alzheimer's disease via modulating ADAM10/17 and its associated neuroprotective signal pathways: A pilot study

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Neuroprotectin D1 Attenuates Blast Overpressure Induced Reactive Microglial Cells in the Cochlea

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Sex-dependent upregulation in oxylipins involved in inflammation resolution in the cerebellum of Niemann-Pick disease C1 mice

Camunas-Alberca, S. M., Morán-Garrido, M., Gaudioso, Á., Souza, F. D. C., Gradillas, A., Ledesma, M. D., Barbas, C., & Taha, A. Y. (2025) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2025.111387 · Cited by 3

Chronic Airway Allergy Induces Pro-Inflammatory Responses in the Brain of Wildtype Mice but Not 3xTgAD Mice

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Modifiable Innate Biology within the Gut–Brain Axis for Alzheimer’s Disease

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Lipid mediators in post-mortem brain samples from patients with Alzheimer's disease: A systematic review

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Antiinflammatory Properties of Dietary n-3 Polyunsaturated Fatty Acids Protect Against Cognitive Decline in Aging and Neurodegenerative Diseases

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Pro-resolving Mediators

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Early Prophylactic Hypothermia for Patients With Severe Traumatic Injury: Premature to Close the Case

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Differential Lipid Mediator Involvement in the Different Forms of Genetic Frontotemporal Dementia: Novel Insights into Neuroinflammation

Sogorb‐Esteve, A., Colas, R. A., Dalli, J., & Rohrer, J. D. (2021) · Journal of Alzheimer s Disease · doi:10.3233/jad-210559 · Cited by 3

Pro-resolving Lipid Mediators Within Brain Esterified Lipid Pools are Reduced in Female Rats Chronically Exposed to Traffic-Related Air Pollution or Genetically Susceptible to Alzheimer’s Disease PhenotypePreprint

Shen, Q. X., Liang, N., Patten, K. T., Otoki, Y., Valenzuela, A. E., Wallis, C., Bein, K. J., Wexler, A. S., Lein, P. J., & Taha, A. Y. (2022) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2022.02.16.480656 · Cited by 3

HMC3 revealed: how much do these “Microglia” really tell us?

Buccarello, L., Privitera, A., Partsinevelos, K., Serwa, K., Carota, G., Pietro, L. D., Cardaci, V., Mangione, R., Sibbitts, J., Lazzarino, G., et al. (2026) · Frontiers in Immunology · doi:10.3389/fimmu.2026.1778798 · Cited by 2

Specialized pro-resolving mediator (SPM)-enriched supplementation modulates inflammatory biomarkers in patients with symptomatic knee osteoarthritis: Blood plasma analysis from the GAUDI study

Möller, I., Rodas, G., Villalón, J. M., Rodas, J. A., Angulo, F., Martínez, N., & Vergés, J. (2026) · Prostaglandins Leukotrienes and Essential Fatty Acids · doi:10.1016/j.plefa.2026.102758 · Cited by 2

Omega-3 Fatty Acids and Alzheimer’s Disease: Toward a New Understanding of Neuroprotective Mechanisms and Intervention Strategies

Galizzi, G. (2026) · Marine Drugs · doi:10.3390/md24070224 · Cited by 2

Palmitoylethanolamid and Other Lipid Autacoids Against Neuroinflammation, Pain, and Spasms in Multiple Sclerosis

Hesselink, J. M. K. (2017) · Elsevier eBooks · doi:10.1016/b978-0-12-805298-3.00004-9 · Cited by 2

Contribution of neuroinflammation, resolution, and neuroprotection in neuropsychiatric diseases

Farooqui, A. A. (2021) · Elsevier eBooks · doi:10.1016/b978-0-323-88460-0.00002-3 · Cited by 2

Contribution of neuroinflammation, resolution, and neuroprotection in neurodegenerative diseases

Farooqui, A. A. (2021) · Elsevier eBooks · doi:10.1016/b978-0-323-88460-0.00010-2 · Cited by 2

Resolvin D1 Induces mTOR-independent and ATG5-dependent Autophagy in BV-2 Microglial Cells

Pan, S., Hu, L., Wang, H., Li, R.-T., He, Y.-J., Shang, Y., Dai, Z.-L., Chen, L., & Xiong, W. (2023) · Current Medical Science · doi:10.1007/s11596-023-2787-5 · Cited by 2

Lack of effects of Resolvin D1 after spinal cord injury in mice

Francos-Quijorna, I., López-González, N., Caro-Canton, M., Sánchez‐Fernández, A., Hernández-Mir, G., & López‐Vales, R. (2025) · Experimental Neurology · doi:10.1016/j.expneurol.2025.115226 · Cited by 2

Resolving acute inflammation; what happens when inflammation goes haywire? How can it get back in line?

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Small Molecule Decoy of Amyloid-β Aggregation Blocks Activation of Microglia-Like Cells

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Air pollution and Alzheimer disease phenotype deplete esterified proresolving lipid mediator reserves in the brain

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Maresin1 mitigates morphine analgesic tolerance via the Lgr6 pathway

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Rescue of Neurons by Resolving Inflammation

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Omega-3 fatty acids and neuroinflammation in Alzheimer's disease: the unraveling of neurorestorative cell signaling

Bazan, N. G. (2016) · Future Neurology · doi:10.2217/fnl-2016-0008 · Cited by 1

The Formyl Peptide Receptor 2 Regulates Microglial Phenotype Through Immunometabolism: Implications for Alzheimer’s Disease

Wickstead, E. S. (2019) · WestminsterResearch (University of Westminster) · doi:10.34737/qy292 · Cited by 1

The Application of Natural Abundance Carbon Isotope Ratio Analysis to Study Brain Fatty Acid Metabolism

Lacombe, R. J. S. (2019) · TSpace (University of Toronto) · Cited by 1

Role of the Specialized Proresolving Mediator in Amyotrophic lateral sclerosisPreprint

Wei, X., Li, X.-X., Sun, H., Qiu, R.-Q., & Yu, X. (2022) · Research Square · doi:10.21203/rs.3.rs-1592743/v1 · Cited by 1

Encapsulation of DHA oil as Pickering emulsion : effect on DHA bioaccessibility and metabolism

Wang, J. (2022) · theses.fr (ABES) · doi:10.70675/8bd2ed1az4d01z4bb6za7a2zc9317ad41d3e · Cited by 1

Rôle des acides gras polyinsaturés n-3 dans le développement cérébral normal et pathologique

Leyrolle, Q. (2018) · theses.fr (ABES) · doi:10.70675/fdca5023zf0e0z4e14za647z153137b2be38

Contribution of Neural Membrane Phospholipids, Sphingolipids, and Cholesterol in the Pathogenesis of Alzheimer’s Disease

Farooqui, A. A. (2017) · Elsevier eBooks · doi:10.1016/b978-0-12-809937-7.00003-3

The effect of phospholipid supplementation on cognitive performance across the lifespan

Champ, C. (2019) · White Rose eTheses Online (University of Leeds, The University of Sheffield, University of York)

Role of Caveolin-1 in microglial phenotype: impact on Glioblastoma

Neto, C. (2021) · ORCA Online Research @Cardiff (Cardiff University)

Role of the Specialized Proresolving Mediator in Amyotrophic lateral sclerosisPreprint

Wei, X., Li, X.-X., Sun, H., Qiu, R.-Q., & Yu, X. (2022) · Research Square · doi:10.21203/rs.3.rs-1592743/v2

The Mediterranean diet: Unsaturated fatty acids and prevention of Alzheimer's disease

Estrada, J. A., & Contreras, I. (2023) · Elsevier eBooks · doi:10.1016/b978-0-323-89834-8.00041-6

Lipid metabolism in neurodegenerative diseases

Bogie, J. F. J., Guns, J., & Vanherle, S. (2023) · Elsevier eBooks · doi:10.1016/b978-0-323-95582-9.00008-5

Étude du rôle de l'obésité dans les pertes cognitives liées à la chirurgie

Tropis, C. (2023) · theses.fr (ABES) · doi:10.70675/f7f83567z03b5z4ff7z8ef8z8a658f3b5ac7

Distinct lipid mediator pathways contribute to neuroinflammation in the temporal and occipital cortex of Alzheimer’s disease subjectsPreprint

Vacondio, D., Coenen, L., Lygeroudi, A., Konings, J., Chornyi, S., Franßen, M., Severin, M., Hof, B. V. H., Karsten, M., van der Pol, S. M. A., et al. (2024) · Research Square · doi:10.21203/rs.3.rs-5456142/v1

Additional file 2 of Age-related changes in brain phospholipids and bioactive lipids in the APP knock-in mouse model of Alzheimer’s disease

Emre, C., Khanh, V., Jun, B., Hjorth, E., Alcalde, S. G., Kautzmann, M.-A. I., Gordon, W. C., Nilsson, P., Bazan, N. G., & Schultzberg, M. (2021) · Figshare · doi:10.6084/m9.figshare.14880548

Additional file 1 of Age-related changes in brain phospholipids and bioactive lipids in the APP knock-in mouse model of Alzheimer’s disease

Emre, C., Khanh, V., Jun, B., Hjorth, E., Alcalde, S. G., Kautzmann, M.-A. I., Gordon, W. C., Nilsson, P., Bazan, N. G., & Schultzberg, M. (2021) · Figshare · doi:10.6084/m9.figshare.14880545

Additional file 5 of Age-related changes in brain phospholipids and bioactive lipids in the APP knock-in mouse model of Alzheimer’s disease

Emre, C., Khanh, V., Jun, B., Hjorth, E., Alcalde, S. G., Kautzmann, M.-A. I., Gordon, W. C., Nilsson, P., Bazan, N. G., & Schultzberg, M. (2021) · Figshare · doi:10.6084/m9.figshare.14880560

Additional file 1 of Lipoxins A4 and B4 inhibit glial cell activation via CXCR3 signaling in acute retinal neuroinflammation

Livne‐Bar, I., Maurya, S., Gronert, K., & Sivak, J. M. (2024) · Figshare · doi:10.6084/m9.figshare.24987777

Additional file 3 of Age-related changes in brain phospholipids and bioactive lipids in the APP knock-in mouse model of Alzheimer’s disease

Emre, C., Khanh, V., Jun, B., Hjorth, E., Alcalde, S. G., Kautzmann, M.-A. I., Gordon, W. C., Nilsson, P., Ng, B., & Schultzberg, M. (2021) · Figshare · doi:10.6084/m9.figshare.14880551

Additional file 1 of Randomized, double-blind, placebo-controlled study to evaluate the effect of treatment with an SPMs-enriched oil on chronic pain and inflammation, functionality, and quality of life in patients with symptomatic knee osteoarthritis: GAUDI study

Möller, I., Rodas, G., Villalón, J. M., Rodas, J. A., Angulo, F., Martínez, N., & Vergés, J. (2024) · Figshare · doi:10.6084/m9.figshare.26600674

Maresin-1 Ameliorates Chronic Unpredictable Stress-Induced Depressive-like Behaviors Associated with Dynamic Modulation of Hippocampal Microglial Activity and TSPO PET Signals

Zheng, A., Qiu, T., Shi, L., Wang, L., Xia, Z., Peng, Z., Kuang, L., & Guo, J. (2026) · Biomedicines · doi:10.3390/biomedicines14020335

Caractérisation de métabolites oxygénés dérivés des acides arachidonique et docosahexaénoïque dans le cerveau de rat

Jouvene, C. C. (2016) · theses.fr (ABES) · doi:10.70675/48490179zca84z4fb2z8a6dzbc32351d6d47

Effets des acides gras ω-3 sur l'inflammation cérébro-vasculaire associée à la maladie d'Alzheimer et aux angiopathies amyloïdes cérébrales

Hur, J. (2017) · theses.fr (ABES) · doi:10.70675/74388921za6fcz4e1ez8033z6d776311f983

Impact d'une supplémentation en actifs d'origine marine sur la neuroinflammation associée au déclin cognitif lié à l'âge

Chataigner, M. (2021) · theses.fr (ABES) · doi:10.70675/a4317690zc4c8z4ba6za738zd457c6bb9b74

Développement d'un agoniste anti-ChemR23 en tant que vecteur de résolution de l'inflammation

Trilleaud, C. (2020) · theses.fr (ABES) · doi:10.70675/40b56131z5a56z4dd4za92bzfd9b187295f2

Resolution of inflammation in Alzheimer’s disease

Wang, X. (2014) · Figshare

Maresin 1 attenuates pro‐inflammatory activation induced by β‐amyloid and stimulates its uptake

Wang, Y., Leppert, A., Tan, S., van der Gaag, B., Li, N., Schultzberg, M., & Hjorth, E. (2021) · Journal of Cellular and Molecular Medicine · doi:10.1111/jcmm.16098 · Cited by 33

P1‐099: ALTERED LIPID MEDIATORS AND RECEPTORS OF RESOLUTION IN THE ENTORHINAL CORTEX OF ALZHEIMER'S DISEASE

Wang, X., Granholm, A., Fitzgerald, J. M., Serhan, C. N., & Schultzberg, M. (2014) · Alzheimer s & Dementia · doi:10.1016/j.jalz.2014.05.335 · Cited by 3

Maresin1 Decreased Microglial Chemotaxis and Ameliorated Inflammation Induced by Amyloid-β 42 in Neuron-Microglia Co-Culture Models

Yin, P., Wang, S., Wei, Y., Wang, X., Zhang, J., Yin, X., Feng, J., & Zhu, M. (2020) · Journal of Alzheimer’s Disease · doi:10.3233/jad-190682 · Cited by 24

P4‐194: STIMULATE RESOLUTION OF INFLAMMATION AS A STRATEGY FOR ALZHEIMER'S DISEASE

Hjorth, E., Zhu, M., & Schultzberg, M. (2014) · Alzheimer s & Dementia · doi:10.1016/j.jalz.2014.05.1711