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Cited by 854

The DOI matches its Crossref record; 37 of the 37 references it cites were found in a registry or an index.

Too little exercise and too much sitting: Inactivity physiology and the need for new recommendations on sedentary behavior

Open access
Hamilton, Marc T., Healy, Genevieve N., Dunstan, David W., Zderic, Theodore W., Owen, Neville·2008·Current Cardiovascular Risk Reports

Abstract

Moderate-to vigorous-intensity physical activity has an established preventive role in cardiovascular disease, type 2 diabetes, obesity, and some cancers. However, recent epidemiologic evidence suggests that sitting time has deleterious cardiovascular and metabolic effects that are independent of whether adults meet physical activity guidelines. Evidence from “inactivity physiology” laboratory studies has identified unique mechanisms that are distinct from the biologic bases of exercising. Opportunities for sedentary behaviors are ubiquitous and are likely to increase with further innovations in technologies. We present a compelling selection of emerging evidence on the deleterious effects of sedentary behavior, as it is underpinned by the unique physiology of inactivity. It is time to consider excessive sitting a serious health hazard, with the potential for ultimately giving consideration to the inclusion of too much sitting (or too few breaks from sitting) in physical activity and health guidelines.

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Crossref · 10.1007/s12170-008-0054-8

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Metadata

Authors
Hamilton, M. T., Healy, G. N., Dunstan, D. W., Zderic, T. W., & Owen, N.
Venue
Current Cardiovascular Risk Reports
Published
2008-07
Volume
2
Issue
4
Pages
292-298
ISSN
  • 1932-9520 (ISSN-L)
  • 1932-9563
OpenAlex
W2087194820
Cited by
854
References
37
FWCI
19.50
Type
journal article
Language
en
Open access
green

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CoChat. (2026). Citation check: Too little exercise and too much sitting: Inactivity physiology and the need for new recommendations on sedentary behavior. https://app.cochat.ai/papers/10.1007/s12170-008-0054-8
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Hamilton, M. T., Healy, G. N., Dunstan, D. W., Zderic, T. W., & Owen, N. (2008). Too little exercise and too much sitting: Inactivity physiology and the need for new recommendations on sedentary behavior. Current Cardiovascular Risk Reports. https://doi.org/10.1007/s12170-008-0054-8

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.