The DOI matches its Crossref record; 37 of the 37 references it cites were found in a registry or an index.
Too little exercise and too much sitting: Inactivity physiology and the need for new recommendations on sedentary behavior
Open accessAbstract
Moderate-to vigorous-intensity physical activity has an established preventive role in cardiovascular disease, type 2 diabetes, obesity, and some cancers. However, recent epidemiologic evidence suggests that sitting time has deleterious cardiovascular and metabolic effects that are independent of whether adults meet physical activity guidelines. Evidence from “inactivity physiology” laboratory studies has identified unique mechanisms that are distinct from the biologic bases of exercising. Opportunities for sedentary behaviors are ubiquitous and are likely to increase with further innovations in technologies. We present a compelling selection of emerging evidence on the deleterious effects of sedentary behavior, as it is underpinned by the unique physiology of inactivity. It is time to consider excessive sitting a serious health hazard, with the potential for ultimately giving consideration to the inclusion of too much sitting (or too few breaks from sitting) in physical activity and health guidelines.
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Cites
Physical Activity in the United States Measured by Accelerometer
TROIANO, R. P., BERRIGAN, D., DODD, K. W., MÂSSE, L. C., TILERT, T., & MCDOWELL, M. (2008) · Medicine & Science in Sports & Exercise · doi:10.1249/mss.0b013e31815a51b3 · Cited by 7,638
HASKELL, W. L., LEE, I.-M., PATE, R. R., POWELL, K. E., BLAIR, S. N., FRANKLIN, B. A., MACERA, C. A., HEATH, G. W., THOMPSON, P. D., & BAUMAN, A. (2007) · Medicine & Science in Sports & Exercise · doi:10.1249/mss.0b013e3180616b27 · Cited by 4,616
Amount of Time Spent in Sedentary Behaviors in the United States, 2003-2004
Matthews, C. E., Chen, K. Y., Freedson, P. S., Buchowski, M. S., Beech, B. M., Pate, R. R., & Troiano, R. P. (2008) · American Journal of Epidemiology · doi:10.1093/aje/kwm390 · Cited by 2,631
CORONARY HEART-DISEASE AND PHYSICAL ACTIVITY OF WORK
Morris, J. N., Heady, J. A., Raffle, P. A. B., Roberts, C. G., & Parks, J. W. (1953) · The Lancet · doi:10.1016/s0140-6736(53)90665-5 · Cited by 1,698
Hamilton, M. T., Hamilton, D. G., & Zderic, T. W. (2007) · Diabetes · doi:10.2337/db07-0882 · Cited by 1,655
Self-citationHealy, G. N., Dunstan, D. W., Salmon, J., Cerin, E., Shaw, J. E., Zimmet, P. Z., & Owen, N. (2008) · Diabetes Care · doi:10.2337/dc07-2046 · Cited by 1,465
Self-citationObjectively Measured Sedentary Time, Physical Activity, and Metabolic Risk
Healy, G. N., Wijndaele, K., Dunstan, D. W., Shaw, J. E., Salmon, J., Zimmet, P. Z., & Owen, N. (2008) · Diabetes Care · doi:10.2337/dc07-1795 · Cited by 1,100
Self-citationSalmon, J., Owen, N., Crawford, D., Bauman, A., & Sallis, J. F. (2003) · Health Psychology · doi:10.1037/0278-6133.22.2.178 · Cited by 915
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Cited by
Too Much Sitting: The Population Health Science of Sedentary Behavior
Owen, N., Healy, G. N., Matthews, C. E., & Dunstan, D. W. (2010) · Exercise and Sport Sciences Reviews · doi:10.1097/jes.0b013e3181e373a2 · Cited by 2,202
Self-citationWilmot, E. G., Edwardson, C. L., Achana, F. A., Davies, M. J., Gorely, T., Gray, L. J., Khunti, K., Yates, T., & Biddle, S. J. H. (2012) · Diabetologia · doi:10.1007/s00125-012-2677-z · Cited by 1,789
Sitting time and mortality from all causes, cardiovascular disease, and cancer
KATZMARZYK, P. T., CHURCH, T. S., CRAIG, C. L., & BOUCHARD, C. (2009) · Medicine & Science in Sports & Exercise · doi:10.1249/mss.0b013e3181930355 · Cited by 1,611
Age Group Comparability of Raw Accelerometer Output from Wrist- and Hip-Worn Monitors
HILDEBRAND, M., VAN HEES, V. T., HANSEN, B. H., & EKELUND, U. (2014) · Medicine & Science in Sports & Exercise · doi:10.1249/mss.0000000000000289 · Cited by 1,043
Sitting time and all-cause mortality risk in 222,497 Australian adults
van der Ploeg, H. P. (2012) · Archives of Internal Medicine · doi:10.1001/archinternmed.2011.2174 · Cited by 884
Metadata
- Authors
- Hamilton, M. T., Healy, G. N., Dunstan, D. W., Zderic, T. W., & Owen, N.
- Venue
- Current Cardiovascular Risk Reports
- Published
- 2008-07
- Volume
- 2
- Issue
- 4
- Pages
- 292-298
- ISSN
- 1932-9520 (ISSN-L)
- 1932-9563
- OpenAlex
- W2087194820
- Cited by
- 854
- References
- 37
- FWCI
- 19.50
- Type
- journal article
- Language
- en
- Open access
- green
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- Hamilton, M. T., Healy, G. N., Dunstan, D. W., Zderic, T. W., & Owen, N. (2008). Too little exercise and too much sitting: Inactivity physiology and the need for new recommendations on sedentary behavior. Current Cardiovascular Risk Reports. https://doi.org/10.1007/s12170-008-0054-8
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.