Objectively Measured Sedentary Time, Physical Activity, and Metabolic Risk
Open accessAbstract
OBJECTIVE—We examined the associations of objectively measured sedentary time and physical activity with continuous indexes of metabolic risk in Australian adults without known diabetes. RESEARCH DESIGN AND METHODS—An accelerometer was used to derive the percentage of monitoring time spent sedentary and in light-intensity and moderate-to-vigorous–intensity activity, as well as mean activity intensity, in 169 Australian Diabetes, Obesity and Lifestyle Study (AusDiab) participants (mean age 53.4 years). Associations with waist circumference, triglycerides, HDL cholesterol, resting blood pressure, fasting plasma glucose, and a clustered metabolic risk score were examined. RESULTS—Independent of time spent in moderate-to-vigorous–intensity activity, there were significant associations of sedentary time, light-intensity time, and mean activity intensity with waist circumference and clustered metabolic risk. Independent of waist circumference, moderate-to-vigorous–intensity activity time was significantly beneficially associated with triglycerides. CONCLUSIONS—These findings highlight the importance of decreasing sedentary time, as well as increasing time spent in physical activity, for metabolic health.
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Sedentary behaviors are emerging as important in determining metabolic risk.
“Finally, the emerging importance of sedentary behaviors in determining metabolic risk ( 106 , 107 ) suggests that future interventions may also benefit from attempting to decrease sitting time and periods of extended sedentary activity.”
From Exercise and Type 2 Diabetes (2010) · cites this paper as [107]
Low-intensity physical activity, defined as 15 minutes per day or 90 minutes per week, can improve fasting glucose and cholesterol and increase life expectancy by 3 years.
“low intensity PA, defined as 15 minutes per day or 90 minutes per week, can help improve fasting glucose, cholesterol, and increase life expectancy by 3 years.”
From The Impact of Physical Activity in Patients With Type 2 Diabetes (2025) · cites this paper as [50]
Recent studies with objectively measured sedentary time data have shown that prolonged time in sedentary behaviors is a cardiometabolic risk factor independent of moderate to vigorous physical activity.
“Recent studies with objectively measured sedentary time data have shown that prolonged time in sedentary behaviors is a cardiometabolic risk factor independent of moderate to vigorous physical activity [6], [7].”
From Association of sedentary time with mortality independent of moderate to vigorous physical activity (2012) · cites this paper as [7]
Light activities, even below moderate intensity, can provide health benefits.
“Interestingly, light activities, even done below the moderate-intensity level (eg, daily tasks done while standing or walking slowly), can provide health benefits [19-21].”
From A Community-Based Physical Activity Counselling Program for People With Knee Osteoarthritis: Feasibility and Preliminary Efficacy of the Track-OA Study (2017) · cites this paper as [20]
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Hawley, J. A., & Gibala, M. J. (2009) · Diabetologia · doi:10.1007/s00125-009-1425-5 · Cited by 41 · see citing works
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Pilcher, J. J., Morris, D. M., Bryant, S. A., Merritt, P. A., & Feigl, H. B. (2017) · Frontiers in Neuroscience · doi:10.3389/fnins.2017.00219 · Cited by 33 · see citing works
Activity Tracker–Based Metrics as Digital Markers of Cardiometabolic Health: Cross-Sectional Study
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Koll, T. T., Semin, J. N., Grieb, B. M., & Dale, W. (2017) · Current Oncology Reports · doi:10.1007/s11912-017-0623-4 · Cited by 16 · see citing works
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Yang, J., Zhang, Y. L., Ye, J., Guo, Q., Sun, Y. N., & Zeng, Q. (2018) · Public Health · doi:10.1016/j.puhe.2018.07.010 · Cited by 9 · see citing works
- Authors
- Healy, G. N., Wijndaele, K., Dunstan, D. W., Shaw, J. E., Salmon, J., Zimmet, P. Z., & Owen, N.
- Affiliations
- The University of Queensland (AU)
- International Diabetes Institute, Melbourne, Australia
- Deakin University (AU)
- ORCID
- Venue
- Diabetes Care
- Publisher
- American Diabetes Association
- Published
- 2008-02-01
- Volume
- 31
- Issue
- 2
- Pages
- 369-371
- ISSN
- 0149-5992 (ISSN-L)
- 1935-5548
- OpenAlex
- W2126096950
- Cited by
- 1,100
- References
- 20
- Citations by year
- 2026: 18 · 2025: 20 · 2024: 23 · 2023: 38 · 2022: 36 · 2021: 56 · 2020: 54 · 2019: 70 · 2018: 83 · 2017: 79 · 2016: 80 · 2015: 101 · 2014: 119 · 2013: 94 · 2012: 62
- FWCI
- 37.54
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Diabetes Care (publishedVersion)
- PubMed (publishedVersion)
- eSpace (Curtin University) (submittedVersion)
- Topics
- Health Sciences › Medicine › Physiology › Physical Activity and Health
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes, Cardiovascular Risks, and Lipoproteins
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Obesity, Physical Activity, Diet
- Keywords
- sedentary behavior, physical activity, metabolic risk, accelerometer-measured activity, light physical activity, waist circumference, triglycerides, HDL cholesterol, blood pressure, fasting blood glucose, adults without diabetes
- MeSH terms
- Adult, Aged, Aged, 80 and over, Australia, Blood Pressure, Diabetes Mellitus, Physical Exertion, Humans, Income, Life Style, Lipids, Middle Aged, Obesity, Regression Analysis, Risk Factors, Triglycerides, Exercise, Patient Selection, Body Size
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