Emerging Technologies for Use in the Study, Diagnosis, and Treatment of Patients with COVID-19
Open accessAbstract
INTRODUCTION: The COVID-19 pandemic has caused an unprecedented health and economic worldwide crisis. Innovative solutions are imperative given limited resources and immediate need for medical supplies, healthcare support and treatments. AIM: The purpose of this review is to summarize emerging technologies being implemented in the study, diagnosis, and treatment of COVID-19. RESULTS: Key focus areas include the applications of artificial intelligence, the use of Big Data and Internet of Things, the importance of mathematical modeling for predictions, utilization of technology for community screening, the use of nanotechnology for treatment and vaccine development, the utility of telemedicine, the implementation of 3D-printing to manage new demands and the potential of robotics. CONCLUSION: The review concludes by highlighting the need for collaboration in the scientific community with open sharing of knowledge, tools, and expertise.
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Robots, including humanoids, performed surgeries and medical operations to limit staff exposure during COVID-19.
“Medical surgeries and operations were also carried out by robots including humanoids to reduce the exposure of medical staff that was already stressed out due to high COVID-19 cases [124, 125].”
From Robotics cyber security: vulnerabilities, attacks, countermeasures, and recommendations (2022) · cites this paper as [124]
The Robotics section (page not provided) says robotic surgery can reduce medical staff exposure during COVID-19 and that robots can perform procedures. It does not identify humanoid robots or establish that they carried out surgeries, rather than describing robotic surgery as an option. (LLM, conf=0.87)
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Cites
COVID-19: consider cytokine storm syndromes and immunosuppression
Mehta, P., McAuley, D. F., Brown, M., Sanchez, E., Tattersall, R. S., & Manson, J. J. (2020) · The Lancet · doi:10.1016/s0140-6736(20)30628-0 · Cited by 9,664 · see citing works
mRNA vaccines — a new era in vaccinology
Pardi, N., Hogan, M. J., Porter, F. W., & Weissman, D. (2018) · Nature Reviews Drug Discovery · doi:10.1038/nrd.2017.243 · Cited by 4,667 · see citing works
Artificial intelligence in radiology
Hosny, A., Parmar, C., Quackenbush, J., Schwartz, L. H., & Aerts, H. J. W. L. (2018) · Nature Reviews Cancer · doi:10.1038/s41568-018-0016-5 · Cited by 3,803 · see citing works
COVID-19 and mental health: A review of the existing literature
Rajkumar, R. P. (2020) · Asian Journal of Psychiatry · doi:10.1016/j.ajp.2020.102066 · Cited by 3,574 · see citing works
Key challenges for delivering clinical impact with artificial intelligence
Kelly, C. J., Karthikesalingam, A., Suleyman, M., Corrado, G., & King, D. (2019) · BMC Medicine · doi:10.1186/s12916-019-1426-2 · Cited by 3,136 · see citing works
Effective treatment of severe COVID-19 patients with tocilizumab
Xu, X., Han, M., Li, T., Sun, W., Wang, D., Fu, B., Zhou, Y., Zheng, X., Yang, Y., Li, X., et al. (2020) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2005615117 · Cited by 2,636 · see citing works
Pathological inflammation in patients with COVID-19: a key role for monocytes and macrophages
Merad, M., & Martin, J. C. (2020) · Nature Reviews Immunology · doi:10.1038/s41577-020-0331-4 · Cited by 2,472 · see citing works
Pharmacologic Treatments for Coronavirus Disease 2019 (COVID-19)
Sanders, J. M., Monogue, M. L., Jodlowski, T. Z., & Cutrell, J. B. (2020) · JAMA · doi:10.1001/jama.2020.6019 · Cited by 2,357 · see citing works
Narin, A., Kaya, C., & Pamuk, Z. (2021) · Pattern Analysis and Applications · doi:10.1007/s10044-021-00984-y · Cited by 2,054 · see citing works
The COVID-19 vaccine development landscape
Le, T. T., Andreadakis, Z., Kumar, A., Román, R. G., Tollefsen, S., Saville, M. K., & Mayhew, S. (2020) · Nature Reviews Drug Discovery · doi:10.1038/d41573-020-00073-5 · Cited by 1,959 · see citing works
Developing Covid-19 Vaccines at Pandemic Speed
Lurie, N., Saville, M., Hatchett, R., & Halton, J. (2020) · New England Journal of Medicine · doi:10.1056/nejmp2005630 · Cited by 1,557 · see citing works
Site-specific glycan analysis of the SARS-CoV-2 spike
Watanabe, Y., Allen, J. D., Wrapp, D., McLellan, J. S., & Crispin, M. (2020) · Science · doi:10.1126/science.abb9983 · Cited by 1,507 · see citing works
Shi, F., Wang, J., Shi, J., Wu, Z., Wang, Q., Tang, Z., He, K., Shi, Y., & Shen, D. (2021) · IEEE Reviews in Biomedical Engineering · doi:10.1109/rbme.2020.2987975 · Cited by 1,404 · see citing works
Response to COVID-19 in Taiwan: Big Data Analytics, New Technology, and Proactive Testing
Wang, C. J., Ng, C. Y., & Brook, R. H. (2020) · JAMA · doi:10.1001/jama.2020.3151 · Cited by 1,391 · see citing works
COVID-19 transforms health care through telemedicine: Evidence from the field
Mann, D. M., Chen, J., Chunara, R., Testa, P. A., & Nov, O. (2020) · Journal of the American Medical Informatics Association · doi:10.1093/jamia/ocaa072 · Cited by 1,361 · see citing works
A human monoclonal antibody blocking SARS-CoV-2 infection
Wang, C., Li, W., Drabek, D., Okba, N. M. A., van Haperen, R., Osterhaus, A. D. M. E., van Kuppeveld, F. J. M., Haagmans, B. L., Grosveld, F. G., & Bosch, B. (2020) · Nature Communications · doi:10.1038/s41467-020-16256-y · Cited by 1,115 · see citing works
Artificial intelligence–enabled rapid diagnosis of patients with COVID-19
Mei, X., Lee, H.-C., Diao, K.-Y., Huang, M., Lin, B., Liu, C., Xie, Z., Ma, Y., Robson, P. M., Chung, M., et al. (2020) · Nature Medicine · doi:10.1038/s41591-020-0931-3 · Cited by 1,084 · see citing works
Randhawa, G. S., Soltysiak, M. P. M., El Roz, H., de Souza, C. P. E., Hill, K. A., & Kari, L. (2020) · PLOS ONE · doi:10.1371/journal.pone.0232391 · Cited by 1,023 · see citing works
Deep Learning-based Detection for COVID-19 from Chest CT using Weak LabelPreprint
Zheng, C., Deng, X., Fu, Q., et al. (2020) · medRxiv · doi:10.1101/2020.03.12.20027185 · Cited by 727 · see citing works
Internet of things (IoT) applications to fight against COVID-19 pandemic
Singh, R. P., Javaid, M., Haleem, A., & Suman, R. (2020) · Diabetes & Metabolic Syndrome: Clinical Research & Reviews · doi:10.1016/j.dsx.2020.04.041 · Cited by 664 · see citing works
Gozes, O., Frid-Adar, M., Greenspan, H. K., Browning, P. D., Zhang, H., Ji, W., Bernheim, A., & Siegel, E. L. (2020) · arXiv (Cornell University) · doi:10.48550/arxiv.2003.05037 · Cited by 638 · see citing works
Dhama, K., Sharun, K., Tiwari, R., Dadar, M., Malik, Y. S., Singh, K. P., & Chaicumpa, W. (2020) · Human Vaccines & Immunotherapeutics · doi:10.1080/21645515.2020.1735227 · Cited by 622 · see citing works
Combating COVID-19—The role of robotics in managing public health and infectious diseases
Yang, G., Nelson, B. J., Murphy, R. R., Choset, H., Christensen, H. I., Collins, S. H., Dario, P., Goldberg, K., Ikuta, K., Jacobstein, N., et al. (2020) · Science Robotics · doi:10.1126/scirobotics.abb5589 · Cited by 564 · see citing works
The race for coronavirus vaccines: a graphical guide
Callaway, E. (2020) · Nature · doi:10.1038/d41586-020-01221-y · Cited by 492 · see citing works
On the responsible use of digital data to tackle the COVID-19 pandemic
Ienca, M., & Vayena, E. (2020) · Nature Medicine · doi:10.1038/s41591-020-0832-5 · Cited by 491 · see citing works
Jiang, X., Coffee, M. P., Bari, A., Wang, J., Jiang, X., Huang, J., Shi, J., Dai, J., Cai, J., Zhang, T., et al. (2020) · Computers, materials & continua/Computers, materials & continua (Print) · doi:10.32604/cmc.2020.010691 · Cited by 450 · see citing works
Special report: The simulations driving the world’s response to COVID-19
Adam, D. (2020) · Nature · doi:10.1038/d41586-020-01003-6 · Cited by 447 · see citing works
A machine learning-based model for survival prediction in patients with severe COVID-19 infectionPreprint
Li, Y., Zhang, H., Gonçalves, J. M., et al. (2020) · medRxiv · doi:10.1101/2020.02.27.20028027 · Cited by 426 · see citing works
Artificial Intelligence Forecasting of Covid-19 in China
Hu, Z., Ge, Q., Li, S., & Xiong, M. (2020) · International Journal of Educational Excellence · doi:10.18562/ijee.054 · Cited by 385 · see citing works
Computational Design of ACE2-Based Peptide Inhibitors of SARS-CoV‑2
Han, Y., & Král, P. (2020) · ACS Nano · doi:10.1021/acsnano.0c02857 · Cited by 378 · see citing works
Artificial intelligence vs COVID-19: limitations, constraints and pitfalls
Naudé, W. (2020) · AI & SOCIETY · doi:10.1007/s00146-020-00978-0 · Cited by 368 · see citing works
Insights from nanomedicine into chloroquine efficacy against COVID-19
Hu, Y., Frieman, M. B., & Wolfram, J. (2020) · Nature Nanotechnology · doi:10.1038/s41565-020-0674-9 · Cited by 321 · see citing works
Replicating and non-replicating viral vectors for vaccine development
Robert-Guroff, M. (2007) · Current Opinion in Biotechnology · doi:10.1016/j.copbio.2007.10.010 · Cited by 276 · see citing works
COVID-19 and the role of 3D printing in medicine
Tino, R., Moore, R. A., Antoline, S., et al. (2020) · 3D Printing in Medicine · doi:10.1186/s41205-020-00064-7 · Cited by 247 · see citing works
Hong, Y.-R., Lawrence, J., Williams Jr, D., & Mainous III, A. (2020) · JMIR Public Health and Surveillance · doi:10.2196/18961 · Cited by 236 · see citing works
Chauhan, V., Galwankar, S., Arquilla, B., Garg, M., Somma, S., El-Menyar, A., Krishnan, V., Gerber, J., Holland, R., & Stawicki, S. (2020) · Journal of Emergencies Trauma and Shock · doi:10.4103/jets.jets_32_20 · Cited by 234 · see citing works
Swennen, G. R. J., Pottel, L., & Haers, P. E. J. J. (2020) · International Journal of Oral and Maxillofacial Surgery · doi:10.1016/j.ijom.2020.03.015 · Cited by 211 · see citing works
Global Preparedness Against COVID-19: We Must Leverage the Power of Digital Health
Mahmood, S., Hasan, K., Carras, M. C., & Labrique, A. B. (2020) · JMIR Public Health and Surveillance · doi:10.2196/18980 · Cited by 201 · see citing works
Pimentel, T. A. P. F., Yan, Z., Jeffers, S. A., Holmes, K. V., Hodges, R. S., & Burkhard, P. (2008) · Chemical Biology & Drug Design · doi:10.1111/j.1747-0285.2008.00746.x · Cited by 182 · see citing works
Applications of 3D Printing Technology to Address COVID-19–Related Supply Shortages
Ishack, S., & Lipner, S. R. (2020) · The American Journal of Medicine · doi:10.1016/j.amjmed.2020.04.002 · Cited by 168 · see citing works
Outbreak dynamics of COVID-19 in China and the United States
Peirlinck, M., Linka, K., Costabal, F. S., & Ellen Kuhl, A. (2020) · Biomechanics and Modeling in Mechanobiology · doi:10.1007/s10237-020-01332-5 · Cited by 152 · see citing works
Yang, T., Gentile, M., Shen, C., et al. (2020) · Diagnostics · doi:10.3390/diagnostics10040224 · Cited by 140 · see citing works
Can mathematical modelling solve the current Covid-19 crisis?
Panovska‐Griffiths, J. (2020) · BMC Public Health · doi:10.1186/s12889-020-08671-z · Cited by 133 · see citing works
Dormont, F., Brusini, R., Cailleau, C., Reynaud, F., Peramo, A., Gendron, A., Mougin, J., Gaudin, F., Varna, M., & Couvreur, P. (2020) · Science Advances · doi:10.1126/sciadv.aaz5466 · Cited by 123 · see citing works
Artificial Intelligence Forecasting of Covid-19 in ChinaPreprint
Hu, Z., Ge, Q., Li, S., et al. (2020) · arXiv (Cornell University) · doi:10.48550/arxiv.2002.07112 · Cited by 117 · see citing works
Kimmig, R., Verheijen, R. H. M., & Rudnicki, M. (2020) · Journal of Gynecologic Oncology · doi:10.3802/jgo.2020.31.e59 · Cited by 117 · see citing works
COVID-19 vaccines: breaking record times to first-in-human trials
Kim, Y. C., Dema, B., & Reyes-Sandoval, A. (2020) · npj Vaccines · doi:10.1038/s41541-020-0188-3 · Cited by 117 · see citing works
Potential 2019-nCoV 3C-like Protease Inhibitors Designed Using Generative Deep Learning ApproachesPreprint
Zhavoronkov, A., Aladinskiy, V., Zhebrak, A., Zagribelnyy, B. A., Terentiev, V. A., Bezrukov, D., Polykovskiy, D. A., Shayakhmetov, R., Filimonov, A., Orekhov, P., et al. (2020) · ChemRxiv · doi:10.26434/chemrxiv.11829102.v1 · Cited by 106 · see citing works
Forecasting and Evaluating Multiple Interventions for COVID-19 Worldwide
Hu, Z., Ge, Q., Li, S., Boerwinkle, E., Li, J., & Xiong, M. (2020) · Frontiers in Artificial Intelligence · doi:10.3389/frai.2020.00041 · Cited by 101 · see citing works
Call for transparency of COVID-19 models
Barton, C. M., Alberti, M., Ames, D. P., Occhipinti, J., Bales, J. D., Burke, E., Chen, M., Diallo, S. Y., Earn, D. J. D., Fath, B. D., et al. (2020) · Science · doi:10.1126/science.abb8637 · Cited by 100 · see citing works
3-D Printed Protective Equipment during COVID-19 Pandemic
Wesemann, C., Pieralli, S., Fretwurst, T., Nold, J., Nelson, K., Schmelzeisen, R., Hellwig, E., & Spies, B. C. (2020) · Materials · doi:10.3390/ma13081997 · Cited by 92 · see citing works
A model society: maths, models and expertise in viral outbreaks
Rhodes, T., Lancaster, K., & Rosengarten, M. (2020) · Critical Public Health · doi:10.1080/09581596.2020.1748310 · Cited by 88 · see citing works
Mohammed, M. N., Hazairin, N. A., Al-Zubaidi, S., et al. (2020) · International Journal of Psychosocial Rehabilitation · doi:10.37200/ijpr/v24i7/pr270220 · Cited by 82 · see citing works
SBDiEM: A new mathematical model of infectious disease dynamics
Bekiros, S. D., & Kouloumpou, D. (2020) · Chaos Solitons & Fractals · doi:10.1016/j.chaos.2020.109828 · Cited by 81 · see citing works
Mohapatra, S., Nath, P., Chatterjee, M., Das, N., Kalita, D., Roy, P., & Satapathi, S. (2020) · PLoS ONE · doi:10.1371/journal.pone.0241543 · Cited by 77 · see citing works
Boosting the arsenal against COVID-19 through computational drug repurposing
Ciliberto, G., & Cardone, L. (2020) · Drug Discovery Today · doi:10.1016/j.drudis.2020.04.005 · Cited by 60 · see citing works
Mathematic modeling of COVID-19 in the United States
Tang, Y., & Wang, S. (2020) · Emerging Microbes & Infections · doi:10.1080/22221751.2020.1760146 · Cited by 58 · see citing works
The Deployment of Drones in Sending Drugs and Patient Blood Samples COVID-19
Anggraeni, S. W., Maulidina, A., Dewi, M. W., et al. (2020) · Indonesian Journal of Science and Technology · doi:10.17509/ijost.v5i2.24462 · Cited by 35 · see citing works
Wang, Y., Lu, X., Zhang, Y., Zhang, X., Wang, K., Liu, J., Li, X., Hu, R., Meng, X., Dou, S., et al. (2020) · EBioMedicine · doi:10.1016/j.ebiom.2020.102724 · Cited by 34 · see citing works
Mohapatra, S., Nath, P., Chatterjee, M., et al. (2020) · medRxiv · doi:10.1101/2020.04.05.20054254 · Cited by 31 · see citing works
Big data integration and analytics to prevent a potential hospital outbreak of COVID-19 in Taiwan
Chen, F., Feng, M., Chen, T., et al. (2020) · Journal of Microbiology Immunology and Infection · doi:10.1016/j.jmii.2020.04.010 · Cited by 23 · see citing works
Logistics of Aggressive Community Screening for Coronavirus 2019
Kaplan, E. H., & Forman, H. P. (2020) · JAMA Health Forum · doi:10.1001/jamahealthforum.2020.0565 · Cited by 17 · see citing works
Report Proposes COVID-19 National Surveillance Plan
Stephenson, J. (2020) · JAMA Health Forum · doi:10.1001/jamahealthforum.2020.0499 · Cited by 6 · see citing works
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Applications of artificial intelligence in battling against covid-19: A literature review
Tayarani N., M.-H. (2021) · Chaos, Solitons & Fractals · doi:10.1016/j.chaos.2020.110338 · Cited by 210 · see citing works
- Authors
- Tsikala Vafea, M., Atalla, E., Georgakas, J., Shehadeh, F., Mylona, E. K., Kalligeros, M., & Mylonakis, E.
- Affiliations
- Brown University (US)
- Corresponding author
- Mylonakis, Eleftherios
- Venue
- Cellular and Molecular Bioengineering
- Published
- 2020-06-24
- Volume
- 13
- Issue
- 4
- Pages
- 249-257
- ISSN
- 1865-5025 (ISSN-L)
- 1865-5033
- PMC
- PMC7314428
- OpenAlex
- W3036966675
- Cited by
- 153
- References
- 63
- Citations by year
- 2026: 2 · 2025: 8 · 2024: 16 · 2023: 14 · 2022: 31 · 2021: 64 · 2020: 18
- FWCI
- 29.88
- Type
- journal article
- Language
- en
- Open access
- hybrid
- doi.org
- Licence
- Locations
- Cellular and Molecular Bioengineering (publishedVersion, other-oa)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Physical Sciences › Computer Science › Information Systems › Healthcare during COVID-19 Pandemic
- Health Sciences › Medicine › Health Informatics › Artificial Intelligence in Healthcare and Education
- Health Sciences › Medicine › Infectious Diseases › COVID-19 Clinical Research Studies
- Keywords
- COVID-19 pandemic, emerging technologies, artificial intelligence, big data, Internet of Things, mathematical modeling, community-based screening, nanotechnology, vaccine development, telemedicine, 3D printing, robotics, diagnosis, treatment
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