Salivary Alpha-Amylase as a Biomarker of Stress in Behavioral Medicine

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Influence of a “Warm Touch” Support Enhancement Intervention Among Married Couples on Ambulatory Blood Pressure, Oxytocin, Alpha Amylase, and Cortisol

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Self-compassion training modulates alpha-amylase, heart rate variability, and subjective responses to social evaluative threat in women

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Salivary Amylase: Digestion and Metabolic Syndrome

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Simultaneous measurement of salivary cortisol and alpha-amylase: Application and recommendations

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Low copy number of the salivary amylase gene predisposes to obesity

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Biologic cost of caring for a cancer patient: dysregulation of pro- and anti-inflammatory signaling pathways

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Individual Differences in AMY1 Gene Copy Number, Salivary α-Amylase Levels, and the Perception of Oral Starch

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The salivary alpha amylase over cortisol ratio as a marker to assess dysregulations of the stress systems

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Chronic stress, salivary cortisol, and α-amylase in children with asthma and healthy children

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Evaluation of Stress Systems by Applying Noninvasive Methodologies: Measurements of Neuroimmune Biomarkers in the Sweat, Heart Rate Variability and Salivary Cortisol

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Salivary α-Amylase Levels after Yohimbine Challenge in Healthy Men

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Salivary flow and alpha-amylase: Collection technique, duration, and oral fluid type

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A Small Randomized Pilot Study of a Workplace Mindfulness-Based Intervention for Surgical Intensive Care Unit Personnel: Effects on Salivary α-Amylase Levels

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Stress management interventions in the workplace improve stress reactivity: a randomised controlled trial

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Giving support to others reduces sympathetic nervous system‐related responses to stress

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Developmental differences in infant salivary alpha-amylase and cortisol responses to stress

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Burnout is associated with reduced parasympathetic activity and reduced hpa axis responsiveness, predominantly in males

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Norepinephrine transporter blocker atomoxetine increases salivary alpha amylase

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Immediate stress reduction effects of yoga during pregnancy: One group pre–post test

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The diurnal course of salivary alpha-amylase in nurses: An investigation of potential confounders and associations with stress

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Differences in saliva collection location and disparities in baseline and diurnal rhythms of alpha-amylase: A preliminary note of caution

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Associations between salivary alpha-amylase and catecholamines--a multilevel modeling approach.

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Reduction in salivary α-amylase levels following a mind–body intervention in cancer survivors—An exploratory study

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Psychophysiological Responses to Stress after Stress Management Training in Patients with Rheumatoid Arthritis

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Biological markers of stress in pediatric acute burn injury

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Effects of maternity yoga on the autonomic nervous system during pregnancy

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Norepinephrine infusion with and without alpha-adrenergic blockade by phentolamine increases salivary alpha amylase in healthy men

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Psychobiological impact of ethnic discrimination in Turkish immigrants living in Germany

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Salivary alpha‐amylase during pregnancy: Diurnal course and associations with obstetric history, maternal demographics, and mood

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Recent trends in behavioral medicine

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The multidimensionality of stress and its assessment

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The pro-inflammatory cytokines, salivary cortisol and alpha-amylase are associated with generalized anxiety disorder (GAD) in patients with asthma

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Salivary Stress-Related Responses in Tinnitus: A Preliminary Study in Young Male Subjects with Tinnitus

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Psychosocial determinants of diurnal alpha-amylase among healthy Quebec workers

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Sexual Orientation and Salivary Alpha-Amylase Diurnal Rhythms in a Cohort of U.S. Young Adults

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Saliva sampling method affects performance of a salivary α‐amylase biosensor

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Diurnal Salivary Alpha-amylase Dynamics among Dementia Family Caregivers

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Reduced professional efficacy is associated with a blunted salivary alpha-amylase awakening response

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Goal-Focused Emotion-Regulation Therapy (GET) for young adult survivors of testicular cancer: a pilot randomized controlled trial of a biobehavioral intervention protocol

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Neuroendocrine Mechanisms of Stress Regulation in Humans

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Saliva Amylase as a Measure of Sympathetic Change Elicited by Autogenic Training in Patients with Functional Somatic Syndromes

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Effects of distraction on negative behaviors and salivary α-amylase under mildly stressful medical procedures for brief inpatient children

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Relationship Between Meditation Depth and Waking Salivary Alpha‐Amylase Secretion Among Long‐Term MBSR Instructors

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Stress Monitoring and Recent Advancements in Wearable Biosensors

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Developments in diagnostic applications of saliva in human organ diseases

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Salivary analysis: An emerging paradigm for non‐invasive healthcare diagnosis and monitoring

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Physiological and affective responses to green space virtual reality among pregnant women

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A Review of Psychological Stress among Students and Its Assessment Using Salivary Biomarkers

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Changes in Salivary Amylase and Glucose in Diabetes: A Scoping Review

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Mental Stress Assessment in the Workplace: A Review

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Evidence for a modulating effect of transcutaneous auricular vagus nerve stimulation (taVNS) on salivary alpha-amylase as indirect noradrenergic marker: A pooled mega-analysis

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Differential responses of salivary cortisol, amylase, and chromogranin A to academic stress

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Music listening and stress recovery in healthy individuals: A systematic review with meta-analysis of experimental studies

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Music performance anxiety from the challenge and threat perspective: psychophysiological and performance outcomes

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Reducing Stress with Yoga: A Systematic Review Based on Multimodal Biosignals

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Psychosocial stress-induced intestinal permeability in healthy humans: What is the evidence?

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Virtual reality environments for stress reduction and management: a scoping review

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Music therapy for health workers to reduce stress, mental workload and anxiety: a systematic review

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Studying caregiver-infant co-regulation in dynamic, diverse cultural contexts: A call to action

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Measurement of Human Stress: A Multidimensional Approach

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Frontal Electroencephalogram Alpha Asymmetry during Mental Stress Related to Workplace Noise

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Psychophysiological assessment of stress reactivity and recovery in anxiety disorders

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Wellbeing of a selection of seafarers in Eastern Adriatic Sea during the COVID-19 pandemic 2020

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Stress response in dissociation and conversion disorders: A systematic review

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Stress and Stress-Induced Glucocorticoids Facilitate Empathic Accuracy in Men but Have No Effects for Women

Nitschke, J. P., Pruessner, J. C., & Bartz, J. A. (2022) · Psychological Science · doi:10.1177/09567976221101315 · Cited by 32 · see citing works

The effects of acute stress on eyewitness memory: An integrative review for eyewitness researchers

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Psychobiological mechanisms underlying the health-beneficial effects of music in people living with dementia: A systematic review of the literature

Hillebrand, M. C., Worschech, F., Wilz, G., Fellgiebel, A., & Wuttke, A. (2021) · Physiology & Behavior · doi:10.1016/j.physbeh.2021.113338 · Cited by 32 · see citing works

Interactive teaching enhances students' physiological arousal during online learning

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Guidelines for the standardization of pre‐analytical variables for salivary biomarker studies in Alzheimer's disease research: An updated review and consensus of the Salivary Biomarkers for Dementia Research Working Group

Ng, T. K. S., Udeh‐Momoh, C. T., Lim, M. A., Gleerup, H. S., Leifert, W. R., Ajalo, C., Ashton, N. J., Zetterberg, H., Rissman, R. A., Winston, C. N., et al. (2024) · Alzheimer s & Dementia · doi:10.1002/alz.14420 · Cited by 30 · see citing works

Early-diagnosis of major depressive disorder: From biomarkers to point-of-care testing

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Factors contributing to stability and instability in alpha-amylase activity in diluted saliva samples over time

Skoluda, N., Dhrami, I., & Nater, U. M. (2020) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2020.104847 · Cited by 28 · see citing works

Cortisol and α-amylase awakening response in children and adolescents with functional neurological (conversion) disorder

Chung, J., Mukerji, S., & Kozlowska, K. (2023) · Australian & New Zealand Journal of Psychiatry · doi:10.1177/00048674221082520 · Cited by 27 · see citing works

Changes in stress pathways as a possible mechanism of aerobic exercise training on brain health: a scoping review of existing studies

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Neurostressology: A systematic review of EEG-based automated mental stress perspectives

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Biomarkers of Stress in Music Interventions: A Systematic Review

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Role of amygdala in stress-induced upregulation of airway IL-1 signaling in asthma

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Methods for eliciting and measuring behavioral and physiological consequences of stress and uncertainty in virtual reality

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Decreased CO2 saturation during circular breathwork supports emergence of altered states of consciousness

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Effects of a Bacopa monnieri extract (Bacognize®) on stress, fatigue, quality of life and sleep in adults with self-reported poor sleep: A randomised, double-blind, placebo-controlled study

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Salivary Biomarkers as a Predictive Factor in Anxiety, Depression, and Stress

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Stress responses in high-fidelity simulation among anesthesiology students

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Hyperarousal, Dissociation, Emotion Dysregulation and Re-Experiencing—Towards Understanding Molecular Aspects of PTSD Symptoms

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The effects of Animal Assisted Therapy on autonomic and endocrine activity in adults with autism spectrum disorder: A randomized controlled trial

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Systemic, Lifestyle and Environmental Modifying Factors in the Pathogenesis of Periodontitis

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Beyond the Bottle: Exploring Health-Promoting Compounds in Wine and Wine-Related Products—Extraction, Detection, Quantification, Aroma Properties, and Terroir Effects

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Impact of Stimulation Duration in taVNS—Exploring Multiple Physiological and Cognitive Outcomes

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From threat to challenge—Improving medical students’ stress response and communication skills performance through the combination of stress arousal reappraisal and preparatory worked example-based learning when breaking bad news to simulated patients: study protocol for a randomized controlled trial

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The Stress Phenotyping Framework: A multidisciplinary biobehavioral approach for assessing and therapeutically targeting maladaptive stress physiology

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Stress Salivary Biomarkers Variation during the Work Day in Emergencies in Healthcare Professionals

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The effect of music on stress recovery

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Salivary Biomarkers (Opiorphin, Cortisol, Amylase, and IgA) Related to Age, Sex, and Stress Perception in a Prospective Cohort of Healthy Schoolchildren

Krahel, A., Paszyńska, E., Otulakowska-Skrzyńska, J., Rzatowski, S., Hernik, A., Słopień, A., Hanć, T., Szcześniewska, P., Bryl, E., Boucher, Y., et al. (2021) · Mediators of Inflammation · doi:10.1155/2021/3639441 · Cited by 18 · see citing works

Exploring the Impact of α-Amylase Enzyme Activity and pH on Flavor Perception of Alcoholic Drinks

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Stress level experienced by participants in realistic simulation: a systematic review

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Association of salivary alpha-amylase with anxiety and stress in nursing professionals

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Neurobiological stress markers in educational research: A systematic review of physiological insights in health science education.

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The Effect of Continuous Intake of Lactobacillus gasseri OLL2716 on Mild to Moderate Delayed Gastric Emptying: A Randomized Controlled Study

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An Impact of Psychological Stress on the Interplay between Salivary Oxidative Stress and the Classic Psychological Stress‐Related Parameters

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The promotion of play behaviour in grow-finish pigs: The relationship between behaviours indicating positive experience and physiological measures

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Motorcycling performance and sleepiness during an extended ride on a dynamic simulator: relationship with stress biomarkers

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Biophysiological stress markers relate differently to grit and school engagement among lower‐ and higher‐track secondary school students

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Effect of transcutaneous vagus nerve stimulation on stress‐reactive neuroendocrine measures in a sample of persons with temporal lobe epilepsy

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The impact of psychological stress on salivary cortisol levels in periodontitis patients: a case-control study

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Salivary Cortisol and Alpha‐Amylase in Posttraumatic Stress Disorder and Their Potential Role in the Evaluation of Cognitive Behavioral Treatment Outcomes

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Multi-trajectory analysis uncovers latent associations between psychological and physiological acute stress response patterns

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Exposure to prenatal stressors and infant autonomic nervous system regulation of stress

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Instructed Partnership Appreciation in Depression: Effects on Mood, Momentary Relationship Satisfaction, and Psychobiological Arousal

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Fluorometric biosensing of α-amylase using an artificial allosteric biosensor immobilized on nanostructured interface

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A psychobioecological model to understand the income-food insecurity-obesity relationship

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Biomarkers of stress and disease

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The Effect of Acute Hypohydration on Indicators of Glycemic Regulation, Appetite, Metabolism and Stress: A Systematic Review and Meta-Analysis

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Goal-Focused Emotion-Regulation Therapy (GET) for young adult survivors of testicular cancer: a pilot randomized controlled trial of a biobehavioral intervention protocol

Hoyt, M. A., Wang, A. W.-T., Ryan, S. J., Breen, E. C., Cheavens, J. S., & Nelson, C. J. (2020) · Trials · doi:10.1186/s13063-020-04242-0 · Cited by 11 · see citing works

The effects of suppressing the biological stress systems on social threat-assessment following acute stress

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Support from parents, teachers, and peers and the moderation of subjective and objective stress of secondary school student

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The Impact of Hearing Aids on Listening Effort and Listening-Related Fatigue - Investigations in a Virtual Realistic Listening Environment

Blümer, M., Heeren, J., Mirkovic, B., Latzel, M., Gordon, C. A., Crowhen, D., Meis, M., Wagener, K. C., & Schulte, M. (2024) · Trends in Hearing · doi:10.1177/23312165241265199 · Cited by 10 · see citing works

Ionising radiation exposure-induced regulation of selected biomarkers and their impact in cancer and treatment

Mzizi, Y., Mbambara, S., Moetlhoa, B., Mahapane, J., Mdanda, S., Sathekge, M. M., & Kgatle, M. (2024) · Frontiers in Nuclear Medicine · doi:10.3389/fnume.2024.1469897 · Cited by 10 · see citing works

Exploring Salivary Alpha-Amylase as a Biomarker in Periodontitis: A Comparative Analysis of Disease Stages and Clinical Correlations

Hashim, N. T., Fathima, S. S., Hisham, N. M., Shivappa, P., Magaogao, M., Islam, M. S., Ahmed, S. F., Babiker, R. A., & Rahman, M. M. (2024) · Current Issues in Molecular Biology · doi:10.3390/cimb46110726 · Cited by 10 · see citing works

Electroencephalographic Biomarkers of Relaxation: A Systematic Review and Meta-analysis

Sugimoto, K., Kurashiki, H., Xu, Y., Takemi, M., & Amano, K. (2026) · Journal of Cognitive Neuroscience · doi:10.1162/jocn.a.2392 · Cited by 10 · see citing works

Real sweating in a virtual stress environment: Investigation of the stress reactivity in people with primary focal hyperhidrosis

Schote, A. B., Dietrich, K., Linden, A. E., Dzionsko, I., Moreno, L. D. L. A. M., Winnikes, U., Zimmer, P., Domes, G., & Meyer, J. (2022) · PLoS ONE · doi:10.1371/journal.pone.0272247 · Cited by 11 · see citing works

Automatic Detection of Subjective, Annotated and Physiological Stress Responses from Video Data

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Can you smell my stress? Influence of stress chemosignals on empathy and emotion recognition in depressed individuals and healthy controls

Wunder, A., Ludwig, J., Haertl, T., Arnhardt, S., Schwinn, L., Chellapandian, D. C., Weinmair, E., Mühle, C., Thürauf, N., Kornhuber, J., et al. (2023) · Physiology & Behavior · doi:10.1016/j.physbeh.2023.114309 · Cited by 10 · see citing works

The independent association between salivary alpha-amylase activity and arterial stiffness in Japanese men and women: the Toon Health Study

Tajima, T., Ikeda, A., Steptoe, A., Takahashi, K., Maruyama, K., Tomooka, K., Saito, I., & Tanigawa, T. (2022) · Hypertension Research · doi:10.1038/s41440-022-00963-8 · Cited by 10 · see citing works

Longitudinal analysis of academic stress and its effects on salivary cortisol, alpha-amylase, and academic outcomes: Study protocol

Castillo-Navarrete, J.-L., Guzmán-Castillo, A., & Bustos, C. (2024) · PLoS ONE · doi:10.1371/journal.pone.0315650 · Cited by 9 · see citing works

Analyzing the Biochemistry of Saliva: Flow, Total Protein, Amylase Enzymatic Activity, and Their Interconnections

Parraça, J. A., Rubio-Zarapuz, A., Tornero-Aguilera, J. F., Clemente‐Suárez, V. J., Tomás-Carús, P., & Costa, A. R. (2025) · International Journal of Molecular Sciences · doi:10.3390/ijms26031164 · Cited by 9 · see citing works

Psychoneuroendocrine interactions in response to the motivational climate in a sport setting: An experimental investigation

Hogue, C. M., Fry, M. D., Fry, A. C., Wineinger, T. O., Chamberlin, J. M., Čabarkapa, D., & Eserhaut, D. A. (2025) · Psychology of sport and exercise · doi:10.1016/j.psychsport.2025.102849 · Cited by 9 · see citing works

The impact of camouflaging autistic traits on psychological and physiological stress: a co-twin control study

Zubizarreta, S. C.-P., Isaksson, J., Faresjö, Å., Faresjö, T., Carracedo, Á., Fernández‐Prieto, M., Bölte, S., & Remnélius, K. L. (2025) · Molecular Autism · doi:10.1186/s13229-025-00695-9 · Cited by 9 · see citing works

Stress Evaluation by Hemoglobin Concentration Change Using Mobile NIRS

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Bioluminescent-Triple-Enzyme-Based Biosensor with Lactate Dehydrogenase for Non-Invasive Training Load Monitoring

Zhukova, G. V., Sutormin, O. S., Егоровна, С. И., Maznyak, N. V., & Kratasyuk, V. A. (2023) · Sensors · doi:10.3390/s23052865 · Cited by 9 · see citing works

Influence of the cooking system, chemical composition, and α-amylase activity on the sensory profile of chestnut cultivars - longal and judia - and their consequence on consumer's acceptability

Santos, M. J., Pinto, T., Mota, J. V. M., Correia, E., & Vilela, A. (2023) · International Journal of Gastronomy and Food Science · doi:10.1016/j.ijgfs.2023.100799 · Cited by 9 · see citing works

Hypnotherapy for procedural pain, itch, and state anxiety in children with acute burns: a feasibility and acceptability study protocol

Geagea, D., Griffin, B. R., Kimble, R. M., Polito, V., Terhune, D. B., & Tyack, Z. F. (2022) · Pilot and Feasibility Studies · doi:10.1186/s40814-022-01017-z · Cited by 9 · see citing works

Immersive virtual plus-maze to examine behavior and psychophysiological-related variables in young people with problematic alcohol and cannabis consumption

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Upregulation of Amy1 in the salivary glands of mice exposed to a lunar gravity environment using the multiple artificial gravity research system

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Salivary Markers as Potential Stress Descriptors for Pediatric Dental Patients: A Literature Review

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Evaluating effects of animal-assisted therapy on pediatric dental care patients

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Prenatal witness stress induces intergenerational anxiety-like behaviors and altered gene expression profiles in male mice

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Examining surgeon stress in robotic and laparoscopic surgery

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Salivary Cortisol Reaction Norms in Zoo-Housed Great Apes: Diurnal Slopes and Intercepts as Indicators of Stress Response Quality

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Salivary α‐Amylase in Biobehavioral Research: Recent Developments and Applications

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Salivary α-Amylase: A Reliable Stress Biomarker

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Is Salivary Alpha Amylase Useful as a Biomarker of Stress in Oral Diseases?

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Is salivary alpha-amylase an indicator of autonomic nervous system dysregulations in mental disorders?—A review of preliminary findings and the interactions with cortisol

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